Peripheral Nervous System

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Helen Morrison - One of the best experts on this subject based on the ideXlab platform.

  • the Peripheral Nervous System in hematopoietic stem cell aging
    Mechanisms of Ageing and Development, 2020
    Co-Authors: Leopold Bohm, Dariolucas Helbing, Nova Oraha, Helen Morrison
    Abstract:

    Abstract Hematopoietic stem cell performance and identity, crucial for homeostasis of the blood-forming System, is governed by extrinsic factors found in the bone marrow microenvironment. Communication within hematopoietic stem cell niches occurs via soluble factors or cell-to-cell contacts between niche and blood-forming cells – which in turn are influenced by Systemic factors distributed by the bone marrow extracellular fluid. Although hematopoietic cell-intrinsic aging contributes to the aging phenotype of the hematopoietic System, the architecture and cellular composition of the bone marrow microenvironment have emerged to be highly dynamic during aging and suggested as a major driver for the functional limitations of the blood System observable in old individuals. Recent attention has been paid to the interface between the Peripheral Nervous System and blood-forming cells in the bone marrow in several clinical contexts and in aging – the latter is reviewed here.

Zhong Lin Wang - One of the best experts on this subject based on the ideXlab platform.

  • artificial tactile Peripheral Nervous System supported by self powered transducers
    Nano Energy, 2021
    Co-Authors: Libo Chen, Chenyu Wen, Shili Zhang, Zhong Lin Wang, Zhibin Zhang
    Abstract:

    Abstract The tactile Peripheral Nervous System innervating human hands, which is essential for sensitive haptic exploration and dexterous object manipulation, features overlapped receptive fields in the skin, arborization of Peripheral neurons and many-to-many synaptic connections. Inspired by the structural features of the natural System, we report a supersensitive artificial slowly adapting tactile afferent Nervous System based on the triboelectric nanogenerator technology. Using tribotronic transistors in the design of mechanoreceptors, the artificial afferent Nervous System exhibits the typical adapting behaviours of the biological counterpart in response to mechanical stimulations. The artificial afferent Nervous System is self-powered in the transduction and event-driven in the operation. Moreover, it has inherent proficiency of neuromorphic signal processing, delivering a minimum resolvable dimension two times smaller than the inter-receptor distance which is the lower limit of the dimension that existing electronic skins can resolve. These results open up a route to scalable neuromorphic skins aiming at the level of human’s exceptional perception for neurorobotic and neuroprosthetic applications.

Zhibin Zhang - One of the best experts on this subject based on the ideXlab platform.

  • artificial tactile Peripheral Nervous System supported by self powered transducers
    Nano Energy, 2021
    Co-Authors: Libo Chen, Chenyu Wen, Shili Zhang, Zhong Lin Wang, Zhibin Zhang
    Abstract:

    Abstract The tactile Peripheral Nervous System innervating human hands, which is essential for sensitive haptic exploration and dexterous object manipulation, features overlapped receptive fields in the skin, arborization of Peripheral neurons and many-to-many synaptic connections. Inspired by the structural features of the natural System, we report a supersensitive artificial slowly adapting tactile afferent Nervous System based on the triboelectric nanogenerator technology. Using tribotronic transistors in the design of mechanoreceptors, the artificial afferent Nervous System exhibits the typical adapting behaviours of the biological counterpart in response to mechanical stimulations. The artificial afferent Nervous System is self-powered in the transduction and event-driven in the operation. Moreover, it has inherent proficiency of neuromorphic signal processing, delivering a minimum resolvable dimension two times smaller than the inter-receptor distance which is the lower limit of the dimension that existing electronic skins can resolve. These results open up a route to scalable neuromorphic skins aiming at the level of human’s exceptional perception for neurorobotic and neuroprosthetic applications.

Leopold Bohm - One of the best experts on this subject based on the ideXlab platform.

  • the Peripheral Nervous System in hematopoietic stem cell aging
    Mechanisms of Ageing and Development, 2020
    Co-Authors: Leopold Bohm, Dariolucas Helbing, Nova Oraha, Helen Morrison
    Abstract:

    Abstract Hematopoietic stem cell performance and identity, crucial for homeostasis of the blood-forming System, is governed by extrinsic factors found in the bone marrow microenvironment. Communication within hematopoietic stem cell niches occurs via soluble factors or cell-to-cell contacts between niche and blood-forming cells – which in turn are influenced by Systemic factors distributed by the bone marrow extracellular fluid. Although hematopoietic cell-intrinsic aging contributes to the aging phenotype of the hematopoietic System, the architecture and cellular composition of the bone marrow microenvironment have emerged to be highly dynamic during aging and suggested as a major driver for the functional limitations of the blood System observable in old individuals. Recent attention has been paid to the interface between the Peripheral Nervous System and blood-forming cells in the bone marrow in several clinical contexts and in aging – the latter is reviewed here.

Brad Bolon - One of the best experts on this subject based on the ideXlab platform.