The Experts below are selected from a list of 531054 Experts worldwide ranked by ideXlab platform
Wei Zhang - One of the best experts on this subject based on the ideXlab platform.
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increased lipid production of the marine oleaginous microalgae isochrysis zhangjiangensis chrysophyta by nitrogen supplement
Bioresource Technology, 2011Co-Authors: Dina Feng, Zhaoan Chen, Wei ZhangAbstract:Effects of nitrate feeding on the cell growth and lipid accumulation of marine microalgae isochrysis zhangjiangensis were investigated. when nitrate was supplied at interval of 24 h, instead of 72 h, a high lipid content of 40.9% and a biomass density of 3.1 g l-1 were obtained. to confirm whether 1. zhangjiangensis accumulates lipid during nitrogen-repletion, a two-stage cultivation method was applied. this algal strain had a high lipid content during sustained nitrate addition and showed a high carbohydrate content under nitrate-Depletion conditions. these results revealed that this algal strain can accumulate lipids under nitrogen-repletion conditions and accumulate carbohydrate under nitrogen-Depletion conditions. when cultured in an extremely high nitrate concentration, 9 g l-1 at 24 h intervals, the growth of algal cells was suppressed, but the highest lipid content of 53% was attained. this special characteristic of lipid accumulation makes i. zhangjiangensis an ideal candidate for producing biodiesel using n-rich wastewater. (c) 2011 elsevier ltd. all rights reserved.
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increased lipid production of the marine oleaginous microalgae isochrysis zhangjiangensis chrysophyta by nitrogen supplement
Bioresource Technology, 2011Co-Authors: Dina Feng, Zhaoan Chen, Song Xue, Wei ZhangAbstract:Effects of nitrate feeding on the cell growth and lipid accumulation of marine microalgae Isochrysis zhangjiangensis were investigated. When nitrate was supplied at interval of 24h, instead of 72 h, a high lipid content of 40.9% and a biomass density of 3.1 g L(-1) were obtained. To confirm whether I. zhangjiangensis accumulates lipid during nitrogen-repletion, a two-stage cultivation method was applied. This algal strain had a high lipid content during sustained nitrate addition and showed a high carbohydrate content under nitrate-Depletion conditions. These results revealed that this algal strain can accumulate lipids under nitrogen-repletion conditions and accumulate carbohydrate under nitrogen-Depletion conditions. When cultured in an extremely high nitrate concentration, 9 g L(-1) at 24h intervals, the growth of algal cells was suppressed, but the highest lipid content of 53% was attained. This special characteristic of lipid accumulation makes I. zhangjiangensis an ideal candidate for producing biodiesel using N-rich wastewater.
Dina Feng - One of the best experts on this subject based on the ideXlab platform.
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increased lipid production of the marine oleaginous microalgae isochrysis zhangjiangensis chrysophyta by nitrogen supplement
Bioresource Technology, 2011Co-Authors: Dina Feng, Zhaoan Chen, Wei ZhangAbstract:Effects of nitrate feeding on the cell growth and lipid accumulation of marine microalgae isochrysis zhangjiangensis were investigated. when nitrate was supplied at interval of 24 h, instead of 72 h, a high lipid content of 40.9% and a biomass density of 3.1 g l-1 were obtained. to confirm whether 1. zhangjiangensis accumulates lipid during nitrogen-repletion, a two-stage cultivation method was applied. this algal strain had a high lipid content during sustained nitrate addition and showed a high carbohydrate content under nitrate-Depletion conditions. these results revealed that this algal strain can accumulate lipids under nitrogen-repletion conditions and accumulate carbohydrate under nitrogen-Depletion conditions. when cultured in an extremely high nitrate concentration, 9 g l-1 at 24 h intervals, the growth of algal cells was suppressed, but the highest lipid content of 53% was attained. this special characteristic of lipid accumulation makes i. zhangjiangensis an ideal candidate for producing biodiesel using n-rich wastewater. (c) 2011 elsevier ltd. all rights reserved.
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increased lipid production of the marine oleaginous microalgae isochrysis zhangjiangensis chrysophyta by nitrogen supplement
Bioresource Technology, 2011Co-Authors: Dina Feng, Zhaoan Chen, Song Xue, Wei ZhangAbstract:Effects of nitrate feeding on the cell growth and lipid accumulation of marine microalgae Isochrysis zhangjiangensis were investigated. When nitrate was supplied at interval of 24h, instead of 72 h, a high lipid content of 40.9% and a biomass density of 3.1 g L(-1) were obtained. To confirm whether I. zhangjiangensis accumulates lipid during nitrogen-repletion, a two-stage cultivation method was applied. This algal strain had a high lipid content during sustained nitrate addition and showed a high carbohydrate content under nitrate-Depletion conditions. These results revealed that this algal strain can accumulate lipids under nitrogen-repletion conditions and accumulate carbohydrate under nitrogen-Depletion conditions. When cultured in an extremely high nitrate concentration, 9 g L(-1) at 24h intervals, the growth of algal cells was suppressed, but the highest lipid content of 53% was attained. This special characteristic of lipid accumulation makes I. zhangjiangensis an ideal candidate for producing biodiesel using N-rich wastewater.
Zhaoan Chen - One of the best experts on this subject based on the ideXlab platform.
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increased lipid production of the marine oleaginous microalgae isochrysis zhangjiangensis chrysophyta by nitrogen supplement
Bioresource Technology, 2011Co-Authors: Dina Feng, Zhaoan Chen, Wei ZhangAbstract:Effects of nitrate feeding on the cell growth and lipid accumulation of marine microalgae isochrysis zhangjiangensis were investigated. when nitrate was supplied at interval of 24 h, instead of 72 h, a high lipid content of 40.9% and a biomass density of 3.1 g l-1 were obtained. to confirm whether 1. zhangjiangensis accumulates lipid during nitrogen-repletion, a two-stage cultivation method was applied. this algal strain had a high lipid content during sustained nitrate addition and showed a high carbohydrate content under nitrate-Depletion conditions. these results revealed that this algal strain can accumulate lipids under nitrogen-repletion conditions and accumulate carbohydrate under nitrogen-Depletion conditions. when cultured in an extremely high nitrate concentration, 9 g l-1 at 24 h intervals, the growth of algal cells was suppressed, but the highest lipid content of 53% was attained. this special characteristic of lipid accumulation makes i. zhangjiangensis an ideal candidate for producing biodiesel using n-rich wastewater. (c) 2011 elsevier ltd. all rights reserved.
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increased lipid production of the marine oleaginous microalgae isochrysis zhangjiangensis chrysophyta by nitrogen supplement
Bioresource Technology, 2011Co-Authors: Dina Feng, Zhaoan Chen, Song Xue, Wei ZhangAbstract:Effects of nitrate feeding on the cell growth and lipid accumulation of marine microalgae Isochrysis zhangjiangensis were investigated. When nitrate was supplied at interval of 24h, instead of 72 h, a high lipid content of 40.9% and a biomass density of 3.1 g L(-1) were obtained. To confirm whether I. zhangjiangensis accumulates lipid during nitrogen-repletion, a two-stage cultivation method was applied. This algal strain had a high lipid content during sustained nitrate addition and showed a high carbohydrate content under nitrate-Depletion conditions. These results revealed that this algal strain can accumulate lipids under nitrogen-repletion conditions and accumulate carbohydrate under nitrogen-Depletion conditions. When cultured in an extremely high nitrate concentration, 9 g L(-1) at 24h intervals, the growth of algal cells was suppressed, but the highest lipid content of 53% was attained. This special characteristic of lipid accumulation makes I. zhangjiangensis an ideal candidate for producing biodiesel using N-rich wastewater.
Nikita S Kolhatkar - One of the best experts on this subject based on the ideXlab platform.
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b cell intrinsic tlr7 signals promote Depletion of the marginal zone in a murine model of wiskott aldrich syndrome
European Journal of Immunology, 2015Co-Authors: Nikita S Kolhatkar, Nicole E Scharping, Jenna M Sullivan, Holly M Jacobs, Marc A Schwartz, Socheath Khim, Luigi D Notarangelo, Adrian J ThrasherAbstract:Patients with Wiskott-Aldrich syndrome (WAS) exhibit prominent defects in splenic marginal zone (MZ), resulting in abnormal T-cell-independent antibody responses and increased bacterial infections. B-cell-intrinsic deletion of the affected gene WAS protein (WASp) markedly reduces splenic MZ B cells, without impacting the rate of MZ B-cell development, suggesting that abnormal B-cell retention within the MZ accounts for MZ defects in WAS. Since WASp regulates integrin-dependent actin cytoskeletal rearrangement, we previously hypothesized that defective B-cell integrin function promotes MZ Depletion. In contrast, we now report that B-cell-intrinsic deletion of the toll-like receptor (TLR) signaling adaptor MyD88 is sufficient to restore the MZ in WAS. We further identify TLR7, an endosomal single-stranded RNA (ssRNA) receptor, as the MyD88-dependent receptor responsible for WAS MZ Depletion. These findings implicate spontaneous activation of MZ B cells by ssRNA-containing self-ligands (likely derived from circulating apoptotic material) as the mechanism underlying MZ Depletion in WAS. Together, these data suggest a previously unappreciated role for B-cell intrinsic TLR signals in MZ homeostasis, of relevance to both pathogen responses and to the development of systemic autoimmunity.
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b cell intrinsic tlr7 signals promote Depletion of the marginal zone in a murine model of wiskott aldrich syndrome
European Journal of Immunology, 2015Co-Authors: Nikita S Kolhatkar, Nicole E Scharping, Jenna M Sullivan, Holly M Jacobs, Marc A Schwartz, Socheath Khim, Luigi D Notarangelo, Adrian J ThrasherAbstract:Patients with Wiskott-Aldrich syndrome (WAS) exhibit prominent defects in splenic marginal zone (MZ), resulting in abnormal T-cell-independent antibody responses and increased bacterial infections. B-cell-intrinsic deletion of the affected gene WAS protein (WASp) markedly reduces splenic MZ B cells, without impacting the rate of MZ B-cell development, suggesting that abnormal B-cell retention within the MZ accounts for MZ defects in WAS. Since WASp regulates integrin-dependent actin cytoskeletal rearrangement, we previously hypothesized that defective B-cell integrin function promotes MZ Depletion. In contrast, we now report that B-cell-intrinsic deletion of the TLR signaling adaptor MyD88 is sufficient to restore the MZ in WAS. We further identify TLR7, an endosomal single-stranded RNA (ssRNA) receptor, as the MyD88-dependent receptor responsible for WAS MZ Depletion. These findings implicate spontaneous activation of MZ B cells by ssRNA-containing self-ligands (likely derived from circulating apoptotic material) as the mechanism underlying MZ Depletion in WAS. Together, these data suggest a previously unappreciated role for B-cell intrinsic TLR signals in MZ homeostasis, of relevance to both pathogen responses and to the development of systemic autoimmunity.
Adrian J Thrasher - One of the best experts on this subject based on the ideXlab platform.
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b cell intrinsic tlr7 signals promote Depletion of the marginal zone in a murine model of wiskott aldrich syndrome
European Journal of Immunology, 2015Co-Authors: Nikita S Kolhatkar, Nicole E Scharping, Jenna M Sullivan, Holly M Jacobs, Marc A Schwartz, Socheath Khim, Luigi D Notarangelo, Adrian J ThrasherAbstract:Patients with Wiskott-Aldrich syndrome (WAS) exhibit prominent defects in splenic marginal zone (MZ), resulting in abnormal T-cell-independent antibody responses and increased bacterial infections. B-cell-intrinsic deletion of the affected gene WAS protein (WASp) markedly reduces splenic MZ B cells, without impacting the rate of MZ B-cell development, suggesting that abnormal B-cell retention within the MZ accounts for MZ defects in WAS. Since WASp regulates integrin-dependent actin cytoskeletal rearrangement, we previously hypothesized that defective B-cell integrin function promotes MZ Depletion. In contrast, we now report that B-cell-intrinsic deletion of the toll-like receptor (TLR) signaling adaptor MyD88 is sufficient to restore the MZ in WAS. We further identify TLR7, an endosomal single-stranded RNA (ssRNA) receptor, as the MyD88-dependent receptor responsible for WAS MZ Depletion. These findings implicate spontaneous activation of MZ B cells by ssRNA-containing self-ligands (likely derived from circulating apoptotic material) as the mechanism underlying MZ Depletion in WAS. Together, these data suggest a previously unappreciated role for B-cell intrinsic TLR signals in MZ homeostasis, of relevance to both pathogen responses and to the development of systemic autoimmunity.
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b cell intrinsic tlr7 signals promote Depletion of the marginal zone in a murine model of wiskott aldrich syndrome
European Journal of Immunology, 2015Co-Authors: Nikita S Kolhatkar, Nicole E Scharping, Jenna M Sullivan, Holly M Jacobs, Marc A Schwartz, Socheath Khim, Luigi D Notarangelo, Adrian J ThrasherAbstract:Patients with Wiskott-Aldrich syndrome (WAS) exhibit prominent defects in splenic marginal zone (MZ), resulting in abnormal T-cell-independent antibody responses and increased bacterial infections. B-cell-intrinsic deletion of the affected gene WAS protein (WASp) markedly reduces splenic MZ B cells, without impacting the rate of MZ B-cell development, suggesting that abnormal B-cell retention within the MZ accounts for MZ defects in WAS. Since WASp regulates integrin-dependent actin cytoskeletal rearrangement, we previously hypothesized that defective B-cell integrin function promotes MZ Depletion. In contrast, we now report that B-cell-intrinsic deletion of the TLR signaling adaptor MyD88 is sufficient to restore the MZ in WAS. We further identify TLR7, an endosomal single-stranded RNA (ssRNA) receptor, as the MyD88-dependent receptor responsible for WAS MZ Depletion. These findings implicate spontaneous activation of MZ B cells by ssRNA-containing self-ligands (likely derived from circulating apoptotic material) as the mechanism underlying MZ Depletion in WAS. Together, these data suggest a previously unappreciated role for B-cell intrinsic TLR signals in MZ homeostasis, of relevance to both pathogen responses and to the development of systemic autoimmunity.
