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A Huber - One of the best experts on this subject based on the ideXlab platform.

  • brain perfusion ct for acute stroke using a 256 slice ct improvement of Diagnostic Information by large volume coverage
    European Radiology, 2011
    Co-Authors: Franziska Dorn, Daniela Muenzel, R Meier, Holger Poppert, Ernst J Rummeny, A Huber
    Abstract:

    To compare a 256-slice CT with a simulated standard CT for brain CT perfusion (CTP). CTP was obtained in 51 patients using a 256-slice CT (128 detector rows, flying z-focus, 8-cm detector width, 80 kV, 120mAs, 20 measurements, 1 CT image/2.5 s). Signal-to-noise ratios (SNR) were compared in grey and white matter. Perfusion maps were evaluated for cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT) in hypoperfused areas and corresponding contralateral regions. Two reconstructed 10-mm slices for simulation of a standard CT (SDCT) were compared with the complete data sets (large-volume CT, LVCT). Adequate image quality was achieved in 50/51 cases. SNR were significantly different in grey and white matter. A perfusion deficit was present in 27 data sets. Differences between the hypoperfusions and the control regions were significant for MTT and CBF, but not for CBV. Three lesions were missed by SDCT but detected by LVCT; 24 lesions were covered incompletely by SDCT, and 6 by LVCT. 21 lesions were detected completely by LVCT, but none by SDCT. CTP imaging of the brain using an increased detector width can detect additional ischaemic lesions and cover most ischaemic lesions completely.

  • brain perfusion ct for acute stroke using a 256 slice ct improvement of Diagnostic Information by large volume coverage
    European Radiology, 2011
    Co-Authors: Franziska Dorn, Daniela Muenzel, R Meier, Holger Poppert, Ernst J Rummeny, A Huber
    Abstract:

    Objectives To compare a 256-slice CT with a simulated standard CT for brain CT perfusion (CTP).

Jonathan J Deeks - One of the best experts on this subject based on the ideXlab platform.

  • graphical presentation of Diagnostic Information
    BMC Medical Research Methodology, 2008
    Co-Authors: Penny Whiting, Marie Westwood, Roger M Harbord, Lucas M Bachmann, Matthias Egger, Jonathan A C Sterne, Jonathan J Deeks
    Abstract:

    BACKGROUND: Graphical displays of results allow researchers to summarise and communicate the key findings of their study. Diagnostic Information should be presented in an easily interpretable way, which conveys both test characteristics (Diagnostic accuracy) and the potential for use in clinical practice (predictive value). METHODS: We discuss the types of graphical display commonly encountered in primary Diagnostic accuracy studies and systematic reviews of such studies, and systematically review the use of graphical displays in recent Diagnostic primary studies and systematic reviews. RESULTS: We identified 57 primary studies and 49 systematic reviews. Fifty-six percent of primary studies and 53% of systematic reviews used graphical displays to present results. Dot-plot or box-and- whisker plots were the most commonly used graph in primary studies and were included in 22 (39%) studies. ROC plots were the most common type of plot included in systematic reviews and were included in 22 (45%) reviews. One primary study and five systematic reviews included a probability-modifying plot. CONCLUSION: Graphical displays are currently underused in primary Diagnostic accuracy studies and systematic reviews of such studies. Diagnostic accuracy studies need to include multiple types of graphic in order to provide both a detailed overview of the results (Diagnostic accuracy) and to communicate Information that can be used to inform clinical practice (predictive value). Work is required to improve graphical displays, to better communicate the utility of a test in clinical practice and the implications of test results for individual patients.

  • graphical presentation of Diagnostic Information
    BMC Medical Research Methodology, 2008
    Co-Authors: Penny Whiting, Marie Westwood, Roger M Harbord, Lucas M Bachmann, Matthias Egger, Jonathan A C Sterne, Jonathan J Deeks
    Abstract:

    Background Graphical displays of results allow researchers to summarise and communicate the key findings of their study. Diagnostic Information should be presented in an easily interpretable way, which conveys both test characteristics (Diagnostic accuracy) and the potential for use in clinical practice (predictive value).

  • graphical presentation of Diagnostic Information
    BMC Medical Research Methodology, 2008
    Co-Authors: Penny Whiting, Marie Westwood, Roger M Harbord, Lucas M Bachmann, Matthias Egger, Jonathan A C Sterne, Jonathan J Deeks
    Abstract:

    Graphical displays of results allow researchers to summarise and communicate the key findings of their study. Diagnostic Information should be presented in an easily interpretable way, which conveys both test characteristics (Diagnostic accuracy) and the potential for use in clinical practice (predictive value). We discuss the types of graphical display commonly encountered in primary Diagnostic accuracy studies and systematic reviews of such studies, and systematically review the use of graphical displays in recent Diagnostic primary studies and systematic reviews. We identified 57 primary studies and 49 systematic reviews. Fifty-six percent of primary studies and 53% of systematic reviews used graphical displays to present results. Dot-plot or box-and- whisker plots were the most commonly used graph in primary studies and were included in 22 (39%) studies. ROC plots were the most common type of plot included in systematic reviews and were included in 22 (45%) reviews. One primary study and five systematic reviews included a probability-modifying plot. Graphical displays are currently underused in primary Diagnostic accuracy studies and systematic reviews of such studies. Diagnostic accuracy studies need to include multiple types of graphic in order to provide both a detailed overview of the results (Diagnostic accuracy) and to communicate Information that can be used to inform clinical practice (predictive value). Work is required to improve graphical displays, to better communicate the utility of a test in clinical practice and the implications of test results for individual patients.

Franziska Dorn - One of the best experts on this subject based on the ideXlab platform.

  • brain perfusion ct for acute stroke using a 256 slice ct improvement of Diagnostic Information by large volume coverage
    European Radiology, 2011
    Co-Authors: Franziska Dorn, Daniela Muenzel, R Meier, Holger Poppert, Ernst J Rummeny, A Huber
    Abstract:

    To compare a 256-slice CT with a simulated standard CT for brain CT perfusion (CTP). CTP was obtained in 51 patients using a 256-slice CT (128 detector rows, flying z-focus, 8-cm detector width, 80 kV, 120mAs, 20 measurements, 1 CT image/2.5 s). Signal-to-noise ratios (SNR) were compared in grey and white matter. Perfusion maps were evaluated for cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT) in hypoperfused areas and corresponding contralateral regions. Two reconstructed 10-mm slices for simulation of a standard CT (SDCT) were compared with the complete data sets (large-volume CT, LVCT). Adequate image quality was achieved in 50/51 cases. SNR were significantly different in grey and white matter. A perfusion deficit was present in 27 data sets. Differences between the hypoperfusions and the control regions were significant for MTT and CBF, but not for CBV. Three lesions were missed by SDCT but detected by LVCT; 24 lesions were covered incompletely by SDCT, and 6 by LVCT. 21 lesions were detected completely by LVCT, but none by SDCT. CTP imaging of the brain using an increased detector width can detect additional ischaemic lesions and cover most ischaemic lesions completely.

  • brain perfusion ct for acute stroke using a 256 slice ct improvement of Diagnostic Information by large volume coverage
    European Radiology, 2011
    Co-Authors: Franziska Dorn, Daniela Muenzel, R Meier, Holger Poppert, Ernst J Rummeny, A Huber
    Abstract:

    Objectives To compare a 256-slice CT with a simulated standard CT for brain CT perfusion (CTP).

R Meier - One of the best experts on this subject based on the ideXlab platform.

  • brain perfusion ct for acute stroke using a 256 slice ct improvement of Diagnostic Information by large volume coverage
    European Radiology, 2011
    Co-Authors: Franziska Dorn, Daniela Muenzel, R Meier, Holger Poppert, Ernst J Rummeny, A Huber
    Abstract:

    To compare a 256-slice CT with a simulated standard CT for brain CT perfusion (CTP). CTP was obtained in 51 patients using a 256-slice CT (128 detector rows, flying z-focus, 8-cm detector width, 80 kV, 120mAs, 20 measurements, 1 CT image/2.5 s). Signal-to-noise ratios (SNR) were compared in grey and white matter. Perfusion maps were evaluated for cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT) in hypoperfused areas and corresponding contralateral regions. Two reconstructed 10-mm slices for simulation of a standard CT (SDCT) were compared with the complete data sets (large-volume CT, LVCT). Adequate image quality was achieved in 50/51 cases. SNR were significantly different in grey and white matter. A perfusion deficit was present in 27 data sets. Differences between the hypoperfusions and the control regions were significant for MTT and CBF, but not for CBV. Three lesions were missed by SDCT but detected by LVCT; 24 lesions were covered incompletely by SDCT, and 6 by LVCT. 21 lesions were detected completely by LVCT, but none by SDCT. CTP imaging of the brain using an increased detector width can detect additional ischaemic lesions and cover most ischaemic lesions completely.

  • brain perfusion ct for acute stroke using a 256 slice ct improvement of Diagnostic Information by large volume coverage
    European Radiology, 2011
    Co-Authors: Franziska Dorn, Daniela Muenzel, R Meier, Holger Poppert, Ernst J Rummeny, A Huber
    Abstract:

    Objectives To compare a 256-slice CT with a simulated standard CT for brain CT perfusion (CTP).

Holger Poppert - One of the best experts on this subject based on the ideXlab platform.

  • brain perfusion ct for acute stroke using a 256 slice ct improvement of Diagnostic Information by large volume coverage
    European Radiology, 2011
    Co-Authors: Franziska Dorn, Daniela Muenzel, R Meier, Holger Poppert, Ernst J Rummeny, A Huber
    Abstract:

    To compare a 256-slice CT with a simulated standard CT for brain CT perfusion (CTP). CTP was obtained in 51 patients using a 256-slice CT (128 detector rows, flying z-focus, 8-cm detector width, 80 kV, 120mAs, 20 measurements, 1 CT image/2.5 s). Signal-to-noise ratios (SNR) were compared in grey and white matter. Perfusion maps were evaluated for cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT) in hypoperfused areas and corresponding contralateral regions. Two reconstructed 10-mm slices for simulation of a standard CT (SDCT) were compared with the complete data sets (large-volume CT, LVCT). Adequate image quality was achieved in 50/51 cases. SNR were significantly different in grey and white matter. A perfusion deficit was present in 27 data sets. Differences between the hypoperfusions and the control regions were significant for MTT and CBF, but not for CBV. Three lesions were missed by SDCT but detected by LVCT; 24 lesions were covered incompletely by SDCT, and 6 by LVCT. 21 lesions were detected completely by LVCT, but none by SDCT. CTP imaging of the brain using an increased detector width can detect additional ischaemic lesions and cover most ischaemic lesions completely.

  • brain perfusion ct for acute stroke using a 256 slice ct improvement of Diagnostic Information by large volume coverage
    European Radiology, 2011
    Co-Authors: Franziska Dorn, Daniela Muenzel, R Meier, Holger Poppert, Ernst J Rummeny, A Huber
    Abstract:

    Objectives To compare a 256-slice CT with a simulated standard CT for brain CT perfusion (CTP).