The Experts below are selected from a list of 126 Experts worldwide ranked by ideXlab platform
Amod Gupta - One of the best experts on this subject based on the ideXlab platform.
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fixed Diameter scan Protocol preferable for retinal nerve fibre layer measurement by optical coherence tomography in all sizes of optic discs
British Journal of Ophthalmology, 2009Co-Authors: Sushmita Kaushik, Surinder Singh Pandav, Parul Ichhpujani, Amod GuptaAbstract:Background: Retinal nerve fibre layer (RNFL) measurements using a fixed-Diameter versus a user-defined scan-Protocol of optical coherence tomography (Stratus OCT) were compared in 32 normal, 62 glaucoma suspects and 36 glaucomatous eyes. Methods: Peripapillary RNFL thickness was measured using the standard “fast” RNFL scan-Protocol and proportional 2.27×disc scan Protocol. Disc size was measured using the “fast” optic disc Protocol. The correlation between RNFL thickness for each scan-Protocol and disc size was analysed. Results: In normal eyes, RNFL thickness was independent of the optic-disc area using the fixed-Diameter Protocol (p = 0.92) but was inversely proportional to disc size using the proportional Protocol (p Conclusion: In normal subjects, disc size does not appear to affect RNFL measurements by OCT using the fixed-Diameter Protocol, thus indicating that RNFL thickness may be related to distance from the centre of the optic disc rather than the margin. The thicker RNFL observed in large glaucomatous discs in this study may be related to the earlier stage of glaucoma, though it may not apply to the general population.
Guo Yanza - One of the best experts on this subject based on the ideXlab platform.
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leak mining of Diameter Protocol flow for ims network
Computer Engineering, 2013Co-Authors: Guo YanzaAbstract:In order to mine the potential vulnerabilities in Diameter Protocol dialog flow of IP Multimedia Subsystem(IMS) abnormal scenarios,this paper proposes a leak mining method of Diameter Protocol flow based on the Genetic Algorithm(GA).The method makes a given scenario by mutating network configuration,user state,and servers' state.And generates multi-dimension fuzziness test data for the scenario using GA.This paper makes decisions that whether there are related vulnerabilities by watching the network's response to the test messages.Simulation experimental result shows that the test messages' generating method both ensures the messages' randomness and improves the effectiveness,it can mine the vulnerabilities of Diameter Protocol flow effectively.
Robert N Weinreb - One of the best experts on this subject based on the ideXlab platform.
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reproducibility of rtvue retinal nerve fiber layer thickness and optic disc measurements and agreement with stratus optical coherence tomography measurements
American Journal of Ophthalmology, 2009Co-Authors: Alberto O Gonzalezgarcia, Gianmarco Vizzeri, Christopher Bowd, Felipe A Medeiros, Linda M Zangwill, Robert N WeinrebAbstract:Purpose To evaluate RTVue spectral-domain optical coherence tomography (OCT) (Optovue Inc, Fremont, California, USA) reproducibility and to assess agreement with Stratus time-domain OCT (Carl Zeiss Meditec, Dublin, California, USA) measurements. Design Observational clinical study. Methods Scans were obtained from both eyes of all participants 3 times using the RTVue nerve head map 4-mm Diameter Protocol and once using Stratus OCT within the same session. RTVue reproducibility and agreement with Stratus OCT were evaluated for retinal nerve fiber layer (RNFL) and optic disc measurements. Results Thirty healthy participants (60 eyes) and 38 glaucoma patients (76 eyes) were included in the study. RTVue reproducibility was good in both healthy participants and patients. For average RNFL thickness, the intraclass correlation coefficients in healthy eyes and patient eyes were 0.97 whereas for rim area they were 0.97 and 0.96, respectively. The correlation between RTVue and Stratus measurements generally was good, especially for average RNFL thickness (healthy eyes and patient eyes, r 2 = 0.82 and 0.86, respectively) and rim volume (healthy eyes and patient eyes, r 2 = 0.78 and 0.76, respectively). Bland-Altman plots showed good agreement between the instruments, with better agreement for average RNFL thickness (95% limits of agreement in healthy eyes and patient eyes, −8.6 to 12 μm and −5.6 to −14.8 μm, respectively) than optic disc parameters. Cup-to-disc ratio 95% limits of agreement in healthy eyes and patient eyes were −0.3 to 0.4 and −0.2 to 0.3, respectively. Optic disc measurements with RTVue were smaller than those with Stratus OCT (eg, disc area was on average 0.4 mm 2 smaller and rim area was 0.3 mm 2 smaller with RTVue). Conclusions Reproducibility of RTVue RNFL and optic disc measurements was excellent in both groups. The level of agreement between RTVue and Stratus measurements suggests that RTVue has the potential to detect glaucomatous structural changes.
Sushmita Kaushik - One of the best experts on this subject based on the ideXlab platform.
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fixed Diameter scan Protocol preferable for retinal nerve fibre layer measurement by optical coherence tomography in all sizes of optic discs
British Journal of Ophthalmology, 2009Co-Authors: Sushmita Kaushik, Surinder Singh Pandav, Parul Ichhpujani, Amod GuptaAbstract:Background: Retinal nerve fibre layer (RNFL) measurements using a fixed-Diameter versus a user-defined scan-Protocol of optical coherence tomography (Stratus OCT) were compared in 32 normal, 62 glaucoma suspects and 36 glaucomatous eyes. Methods: Peripapillary RNFL thickness was measured using the standard “fast” RNFL scan-Protocol and proportional 2.27×disc scan Protocol. Disc size was measured using the “fast” optic disc Protocol. The correlation between RNFL thickness for each scan-Protocol and disc size was analysed. Results: In normal eyes, RNFL thickness was independent of the optic-disc area using the fixed-Diameter Protocol (p = 0.92) but was inversely proportional to disc size using the proportional Protocol (p Conclusion: In normal subjects, disc size does not appear to affect RNFL measurements by OCT using the fixed-Diameter Protocol, thus indicating that RNFL thickness may be related to distance from the centre of the optic disc rather than the margin. The thicker RNFL observed in large glaucomatous discs in this study may be related to the earlier stage of glaucoma, though it may not apply to the general population.
Alberto O Gonzalezgarcia - One of the best experts on this subject based on the ideXlab platform.
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reproducibility of rtvue retinal nerve fiber layer thickness and optic disc measurements and agreement with stratus optical coherence tomography measurements
American Journal of Ophthalmology, 2009Co-Authors: Alberto O Gonzalezgarcia, Gianmarco Vizzeri, Christopher Bowd, Felipe A Medeiros, Linda M Zangwill, Robert N WeinrebAbstract:Purpose To evaluate RTVue spectral-domain optical coherence tomography (OCT) (Optovue Inc, Fremont, California, USA) reproducibility and to assess agreement with Stratus time-domain OCT (Carl Zeiss Meditec, Dublin, California, USA) measurements. Design Observational clinical study. Methods Scans were obtained from both eyes of all participants 3 times using the RTVue nerve head map 4-mm Diameter Protocol and once using Stratus OCT within the same session. RTVue reproducibility and agreement with Stratus OCT were evaluated for retinal nerve fiber layer (RNFL) and optic disc measurements. Results Thirty healthy participants (60 eyes) and 38 glaucoma patients (76 eyes) were included in the study. RTVue reproducibility was good in both healthy participants and patients. For average RNFL thickness, the intraclass correlation coefficients in healthy eyes and patient eyes were 0.97 whereas for rim area they were 0.97 and 0.96, respectively. The correlation between RTVue and Stratus measurements generally was good, especially for average RNFL thickness (healthy eyes and patient eyes, r 2 = 0.82 and 0.86, respectively) and rim volume (healthy eyes and patient eyes, r 2 = 0.78 and 0.76, respectively). Bland-Altman plots showed good agreement between the instruments, with better agreement for average RNFL thickness (95% limits of agreement in healthy eyes and patient eyes, −8.6 to 12 μm and −5.6 to −14.8 μm, respectively) than optic disc parameters. Cup-to-disc ratio 95% limits of agreement in healthy eyes and patient eyes were −0.3 to 0.4 and −0.2 to 0.3, respectively. Optic disc measurements with RTVue were smaller than those with Stratus OCT (eg, disc area was on average 0.4 mm 2 smaller and rim area was 0.3 mm 2 smaller with RTVue). Conclusions Reproducibility of RTVue RNFL and optic disc measurements was excellent in both groups. The level of agreement between RTVue and Stratus measurements suggests that RTVue has the potential to detect glaucomatous structural changes.