Dietary Intervention

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Christos Manes - One of the best experts on this subject based on the ideXlab platform.

  • obese patients with type 2 diabetes on conventional versus intensive insulin therapy efficacy of low calorie Dietary Intervention
    Advances in Therapy, 2016
    Co-Authors: Dimitrios Baltzis, Maria G Grammatikopoulou, Nikolaos Papanas, Christinamaria Trakatelli, Evangelia Kintiraki, Maria Hassapidou, Christos Manes
    Abstract:

    Introduction The aim of this prospective study was to assess the results of a standard low-calorie Dietary Intervention (7.5 MJ/day) on body weight (BW) and the metabolic profile of obese patients with type 2 diabetes mellitus (T2DM) on intensive insulin therapy (IIT: 4 insulin injections/day) versus conventional insulin therapy (CIT: 2/3 insulin injections/day).

  • Obese Patients with Type 2 Diabetes on Conventional Versus Intensive Insulin Therapy: Efficacy of Low-Calorie Dietary Intervention
    Advances in Therapy, 2016
    Co-Authors: Dimitrios Baltzis, Maria G Grammatikopoulou, Nikolaos Papanas, Christinamaria Trakatelli, Evangelia Kintiraki, Maria Hassapidou, Christos Manes
    Abstract:

    Introduction The aim of this prospective study was to assess the results of a standard low-calorie Dietary Intervention (7.5 MJ/day) on body weight (BW) and the metabolic profile of obese patients with type 2 diabetes mellitus (T2DM) on intensive insulin therapy (IIT: 4 insulin injections/day) versus conventional insulin therapy (CIT: 2/3 insulin injections/day). Methods A total of 60 patients ( n  = 60, 23 males and 37 postmenopausal females) were recruited and categorized into two groups according to the scheme of insulin treatment. Thirty were on IIT (13 males and 17 females) and an equal number on CIT (10 males and 20 females). BW, body mass index (BMI), HbA1c, and metabolic parameters were compared at 6 and 12 months after baseline. Results Significant reductions were observed in the BW, BMI, HbA1c ( p  ≤ 0.001 for all) and cholesterol ( p  ≤ 0.05) at 6 months post-Intervention. At 1 year, median BW reduction was 4.5 kg (3.3, 5.8) for patients on IIT and 4.8 kg (3.6, 7.0) for those on CIT. The 12-month Dietary Intervention increased prevalence of normoglycemia in the IIT group and reduced the prevalence of obesity prevalence among the CIT participants (all p  

Dana Laake - One of the best experts on this subject based on the ideXlab platform.

  • Comprehensive nutritional and Dietary Intervention for autism spectrum disorder—a randomized, controlled 12-month trial
    Nutrients, 2018
    Co-Authors: James B Adams, Valeria Fimbres, Elena L. Pollard, Robert Hellmers, Tapan Audhya, Elizabeth Geis, Jessica Mitchell, Julie Ingram, Eva Gehn, Dana Laake
    Abstract:

    This study involved a randomized, controlled, single-blind 12-month treatment study of a comprehensive nutritional and Dietary Intervention. Participants were 67 children and adults with autism spectrum disorder (ASD) ages 3–58 years from Arizona and 50 non-sibling neurotypical controls of similar age and gender. Treatment began with a special vitamin/mineral supplement, and additional treatments were added sequentially, including essential fatty acids, Epsom salt baths, carnitine, digestive enzymes, and a healthy gluten-free, casein-free, soy-free (HGCSF) diet. There was a significant improvement in nonverbal intellectual ability in the treatment group compared to the non-treatment group (+6.7 ± 11 IQ points vs. −0.6 ± 11 IQ points, p = 0.009) based on a blinded clinical assessment. Based on semi-blinded assessment, the treatment group, compared to the non-treatment group, had significantly greater improvement in autism symptoms and developmental age. The treatment group had significantly greater increases in EPA, DHA, carnitine, and vitamins A, B2, B5, B6, B12, folic acid, and Coenzyme Q10. The positive results of this study suggest that a comprehensive nutritional and Dietary Intervention is effective at improving nutritional status, non-verbal IQ, autism symptoms, and other symptoms in most individuals with ASD. Parents reported that the vitamin/mineral supplements, essential fatty acids, and HGCSF diet were the most beneficial.

  • comprehensive nutritional and Dietary Intervention for autism spectrum disorder a randomized controlled 12 month trial
    Nutrients, 2018
    Co-Authors: James B Adams, Valeria Fimbres, Robert Hellmers, Tapan Audhya, Elizabeth Geis, Jessica Mitchell, Julie Ingram, Eva Gehn, Elena Pollard, Dana Laake
    Abstract:

    This study involved a randomized, controlled, single-blind 12-month treatment study of a comprehensive nutritional and Dietary Intervention. Participants were 67 children and adults with autism spectrum disorder (ASD) ages 3–58 years from Arizona and 50 non-sibling neurotypical controls of similar age and gender. Treatment began with a special vitamin/mineral supplement, and additional treatments were added sequentially, including essential fatty acids, Epsom salt baths, carnitine, digestive enzymes, and a healthy gluten-free, casein-free, soy-free (HGCSF) diet. There was a significant improvement in nonverbal intellectual ability in the treatment group compared to the non-treatment group (+6.7 ± 11 IQ points vs. −0.6 ± 11 IQ points, p = 0.009) based on a blinded clinical assessment. Based on semi-blinded assessment, the treatment group, compared to the non-treatment group, had significantly greater improvement in autism symptoms and developmental age. The treatment group had significantly greater increases in EPA, DHA, carnitine, and vitamins A, B2, B5, B6, B12, folic acid, and Coenzyme Q10. The positive results of this study suggest that a comprehensive nutritional and Dietary Intervention is effective at improving nutritional status, non-verbal IQ, autism symptoms, and other symptoms in most individuals with ASD. Parents reported that the vitamin/mineral supplements, essential fatty acids, and HGCSF diet were the most beneficial.

Dimitrios Baltzis - One of the best experts on this subject based on the ideXlab platform.

  • obese patients with type 2 diabetes on conventional versus intensive insulin therapy efficacy of low calorie Dietary Intervention
    Advances in Therapy, 2016
    Co-Authors: Dimitrios Baltzis, Maria G Grammatikopoulou, Nikolaos Papanas, Christinamaria Trakatelli, Evangelia Kintiraki, Maria Hassapidou, Christos Manes
    Abstract:

    Introduction The aim of this prospective study was to assess the results of a standard low-calorie Dietary Intervention (7.5 MJ/day) on body weight (BW) and the metabolic profile of obese patients with type 2 diabetes mellitus (T2DM) on intensive insulin therapy (IIT: 4 insulin injections/day) versus conventional insulin therapy (CIT: 2/3 insulin injections/day).

  • Obese Patients with Type 2 Diabetes on Conventional Versus Intensive Insulin Therapy: Efficacy of Low-Calorie Dietary Intervention
    Advances in Therapy, 2016
    Co-Authors: Dimitrios Baltzis, Maria G Grammatikopoulou, Nikolaos Papanas, Christinamaria Trakatelli, Evangelia Kintiraki, Maria Hassapidou, Christos Manes
    Abstract:

    Introduction The aim of this prospective study was to assess the results of a standard low-calorie Dietary Intervention (7.5 MJ/day) on body weight (BW) and the metabolic profile of obese patients with type 2 diabetes mellitus (T2DM) on intensive insulin therapy (IIT: 4 insulin injections/day) versus conventional insulin therapy (CIT: 2/3 insulin injections/day). Methods A total of 60 patients ( n  = 60, 23 males and 37 postmenopausal females) were recruited and categorized into two groups according to the scheme of insulin treatment. Thirty were on IIT (13 males and 17 females) and an equal number on CIT (10 males and 20 females). BW, body mass index (BMI), HbA1c, and metabolic parameters were compared at 6 and 12 months after baseline. Results Significant reductions were observed in the BW, BMI, HbA1c ( p  ≤ 0.001 for all) and cholesterol ( p  ≤ 0.05) at 6 months post-Intervention. At 1 year, median BW reduction was 4.5 kg (3.3, 5.8) for patients on IIT and 4.8 kg (3.6, 7.0) for those on CIT. The 12-month Dietary Intervention increased prevalence of normoglycemia in the IIT group and reduced the prevalence of obesity prevalence among the CIT participants (all p  

Sylwia M Figarska - One of the best experts on this subject based on the ideXlab platform.

Evangelia Kintiraki - One of the best experts on this subject based on the ideXlab platform.

  • obese patients with type 2 diabetes on conventional versus intensive insulin therapy efficacy of low calorie Dietary Intervention
    Advances in Therapy, 2016
    Co-Authors: Dimitrios Baltzis, Maria G Grammatikopoulou, Nikolaos Papanas, Christinamaria Trakatelli, Evangelia Kintiraki, Maria Hassapidou, Christos Manes
    Abstract:

    Introduction The aim of this prospective study was to assess the results of a standard low-calorie Dietary Intervention (7.5 MJ/day) on body weight (BW) and the metabolic profile of obese patients with type 2 diabetes mellitus (T2DM) on intensive insulin therapy (IIT: 4 insulin injections/day) versus conventional insulin therapy (CIT: 2/3 insulin injections/day).

  • Obese Patients with Type 2 Diabetes on Conventional Versus Intensive Insulin Therapy: Efficacy of Low-Calorie Dietary Intervention
    Advances in Therapy, 2016
    Co-Authors: Dimitrios Baltzis, Maria G Grammatikopoulou, Nikolaos Papanas, Christinamaria Trakatelli, Evangelia Kintiraki, Maria Hassapidou, Christos Manes
    Abstract:

    Introduction The aim of this prospective study was to assess the results of a standard low-calorie Dietary Intervention (7.5 MJ/day) on body weight (BW) and the metabolic profile of obese patients with type 2 diabetes mellitus (T2DM) on intensive insulin therapy (IIT: 4 insulin injections/day) versus conventional insulin therapy (CIT: 2/3 insulin injections/day). Methods A total of 60 patients ( n  = 60, 23 males and 37 postmenopausal females) were recruited and categorized into two groups according to the scheme of insulin treatment. Thirty were on IIT (13 males and 17 females) and an equal number on CIT (10 males and 20 females). BW, body mass index (BMI), HbA1c, and metabolic parameters were compared at 6 and 12 months after baseline. Results Significant reductions were observed in the BW, BMI, HbA1c ( p  ≤ 0.001 for all) and cholesterol ( p  ≤ 0.05) at 6 months post-Intervention. At 1 year, median BW reduction was 4.5 kg (3.3, 5.8) for patients on IIT and 4.8 kg (3.6, 7.0) for those on CIT. The 12-month Dietary Intervention increased prevalence of normoglycemia in the IIT group and reduced the prevalence of obesity prevalence among the CIT participants (all p