The Experts below are selected from a list of 255 Experts worldwide ranked by ideXlab platform

Yuki Ohno - One of the best experts on this subject based on the ideXlab platform.

  • Disseminated Herpes Zoster infection with urinary retention and incontinence
    Journal of Infectious Diseases and Therapy, 2020
    Co-Authors: Yuta Norimatsu, Yuki Ohno
    Abstract:

    Herpes Zoster is one of the most commonly encountered dermatological diseases. Disseminated Herpes Zoster is one of the severe forms of a Herpes Zoster infection. Patients with Herpes Zoster occasionally experience urinary retention and incontinence, which can greatly affect their quality of life. Urinary retention and incontinence appear to improve with or after the treatment of Herpes Zoster. There are some reports of urinary retention caused by Herpes Zoster, but case reports of incontinence are rare. Here a case of Disseminated Herpes Zoster is reported that caused both urinary retention and incontinence. An 87-year-old woman visited the JR Tokyo General Hospital with complaints of erythema and headache in the right forehead, pain in the left buttock, and urinary retention that had started two days prior. Two days after the onset, the patient was hospitalized (Day 0) and treatment with acyclovir (750 mg/day) was initiated. For urinary retention, in addition to indwelling a urinary catheter, distigmine bromide at 5 mg/day was initiated. After admission, the patient experienced bowel incontinence on Day 1. Continued acyclovir treatment eliminated the blisters and alleviated pain, and incontinence did not reoccur after Day 2. At the end of the acyclovir administration, an attempt was made to remove the urinary tract catheter, but the catheter was reinserted the same day because urinary retention continued. The urinary tract catheter was ultimately removed on Day 36, after which urinary retention did not reoccur, even after distigmine bromide treatment was completed on Day 71. Similar to previous reports., it is thought that a skin rash on the head or buttocks or the onset of the disease in the elderly may be an indication for disease course with higher risk of incontinence. As the case described here was of an elderly woman with Disseminated Herpes Zoster with skin eruptions on the face and left buttock, the combination of symptoms and the patient’s older age placed her at higher risk for incontinence. Patients with Herpes Zoster on the face who were previously reported with urinary retention also had a skin rash on the trunk. Urinary retention without a skin rash on the trunk is considered rare. Moreover, blood tests for this case did not indicate renal dysfunction. Urinary disorders due to Herpes Zoster and renal dysfunction identified by blood tests may not be related.

Erik J Stratman - One of the best experts on this subject based on the ideXlab platform.

  • visceral Zoster as the presenting feature of Disseminated Herpes Zoster
    Journal of The American Academy of Dermatology, 2002
    Co-Authors: Erik J Stratman
    Abstract:

    Abstract Visceral dissemination of Herpes Zoster may follow cutaneous dissemination in immunocompromised patients. The skin is not necessarily the only organ affected and may not even be the presenting organ. Immunohistochemical stains available for routine paraffin-embedded tissue biopsy specimens allow for rapid diagnosis of varicella Zoster virus. We describe a patient in whom gastric dissemination of Herpes Zoster was proven by immunohistochemistry. Unexplained hepatitis, pancreatitis, gastritis, or complaints of abdominal pain in immunocompromised patients with Herpes Zoster should prompt a high degree of suspicion for visceral Zoster and immediate treatment with intravenous acyclovir. (J Am Acad Dermatol 2002;46:771-4.)

Hyun-soon Jeon - One of the best experts on this subject based on the ideXlab platform.

  • Risk factors of severe infections in patients with rheumatoid arthritis treated with leflunomide
    Modern Rheumatology, 2013
    Co-Authors: Hea Min Yu, Hyun-soon Jeon
    Abstract:

    Objectives To determine the risk of severe infection requiring or complicating hospitalization associated with leflunomide therapy in patients with rheumatoid arthritis (RA). Methods We performed a retrospective study of RA patients who were prescribed leflunomide between 2004 and 2011. Background clinical and laboratory features were compared between patients who suffered severe leflunomide-associated infections and those who did not. Results Since January 2005, 401 RA patients have started on leflunomide. Among those, 33 (8.2 %) developed severe infections: pneumonia, oral candidiasis, pyelonephritis, pulmonary tuberculosis, cellulitis, Disseminated Herpes Zoster, tonsillitis, and pulmonary cryptococcosis. Logistic regression showed that age at entry, the presence of DM, and daily dosage of corticosteroid were associated with development of severe infections. Conclusions These results showed that some patients with RA who were taking leflunomide developed severe infections requiring hospitalization, and that older age, DM, and a higher daily dosage of corticosteroid were risk factors associated with leflunomide-associated severe infections.

Jorge D Blanco - One of the best experts on this subject based on the ideXlab platform.

Yuta Norimatsu - One of the best experts on this subject based on the ideXlab platform.

  • Disseminated Herpes Zoster infection with urinary retention and incontinence
    Journal of Infectious Diseases and Therapy, 2020
    Co-Authors: Yuta Norimatsu, Yuki Ohno
    Abstract:

    Herpes Zoster is one of the most commonly encountered dermatological diseases. Disseminated Herpes Zoster is one of the severe forms of a Herpes Zoster infection. Patients with Herpes Zoster occasionally experience urinary retention and incontinence, which can greatly affect their quality of life. Urinary retention and incontinence appear to improve with or after the treatment of Herpes Zoster. There are some reports of urinary retention caused by Herpes Zoster, but case reports of incontinence are rare. Here a case of Disseminated Herpes Zoster is reported that caused both urinary retention and incontinence. An 87-year-old woman visited the JR Tokyo General Hospital with complaints of erythema and headache in the right forehead, pain in the left buttock, and urinary retention that had started two days prior. Two days after the onset, the patient was hospitalized (Day 0) and treatment with acyclovir (750 mg/day) was initiated. For urinary retention, in addition to indwelling a urinary catheter, distigmine bromide at 5 mg/day was initiated. After admission, the patient experienced bowel incontinence on Day 1. Continued acyclovir treatment eliminated the blisters and alleviated pain, and incontinence did not reoccur after Day 2. At the end of the acyclovir administration, an attempt was made to remove the urinary tract catheter, but the catheter was reinserted the same day because urinary retention continued. The urinary tract catheter was ultimately removed on Day 36, after which urinary retention did not reoccur, even after distigmine bromide treatment was completed on Day 71. Similar to previous reports., it is thought that a skin rash on the head or buttocks or the onset of the disease in the elderly may be an indication for disease course with higher risk of incontinence. As the case described here was of an elderly woman with Disseminated Herpes Zoster with skin eruptions on the face and left buttock, the combination of symptoms and the patient’s older age placed her at higher risk for incontinence. Patients with Herpes Zoster on the face who were previously reported with urinary retention also had a skin rash on the trunk. Urinary retention without a skin rash on the trunk is considered rare. Moreover, blood tests for this case did not indicate renal dysfunction. Urinary disorders due to Herpes Zoster and renal dysfunction identified by blood tests may not be related.