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Fredrick W Schueler - One of the best experts on this subject based on the ideXlab platform.
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Hormonal induction of spawning in 4 species of frogs by coinjection with a gonadotropin-releasing hormone agonist and a Dopamine Antagonist
Reproductive Biology and Endocrinology, 2010Co-Authors: Vance L Trudeau, Gustavo M Somoza, Guillermo S Natale, Bruce Pauli, Jacqui Wignall, Paula Jackman, Ken Doe, Fredrick W SchuelerAbstract:Background It is well known that many anurans do not reproduce easily in captivity. Some methods are based on administration of mammalian hormones such as human chorionic gonadotropin, which are not effective in many frogs. There is a need for simple, cost-effective alternative techniques to induce spawning. Methods Our new method is based on the injection of a combination of a gonadotropin-releasing hormone (GnRH) agonist and a Dopamine Antagonist. We have named this formulation AMPHIPLEX, which is derived from the combination of the words amphibian and amplexus. This name refers to the specific reproductive behavior of frogs when the male mounts and clasps the female to induce ovulation and to fertilize the eggs as they are laid. Results We describe the use of the method and demonstrate its applicability for captive breeding in 3 different anuran families. We tested several combinations of GnRH agonists with Dopamine Antagonists using Lithobates pipiens. The combination of des-Gly^10, D-Ala^6, Pro-LHRH (0.4 microrams/g body weight) and metoclopramide (10 micrograms/g BWt. MET) was most effective. It was used in-season, after short-term captivity and in frogs artificially hibernated under laboratory conditions. The AMPHIPLEX method was also effective in 3 Argentinian frogs, Ceratophrys ornata , Ceratophrys cranwelli and Odontophrynus americanus . Conclusion Our approach offers some advantages over other hormonally-based techniques. Both sexes are injected only once and at the same time, reducing handling stress. AMPHIPLEX is a new reproductive management tool for captive breeding in Anura.
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hormonal induction of spawning in 4 species of frogs by coinjection with a gonadotropin releasing hormone agonist and a Dopamine Antagonist
Reproductive Biology and Endocrinology, 2010Co-Authors: Vance L Trudeau, Gustavo M Somoza, Guillermo S Natale, Jacqui Wignall, Paula Jackman, Ken Doe, Bruce D Pauli, Fredrick W SchuelerAbstract:It is well known that many anurans do not reproduce easily in captivity. Some methods are based on administration of mammalian hormones such as human chorionic gonadotropin, which are not effective in many frogs. There is a need for simple, cost-effective alternative techniques to induce spawning. Our new method is based on the injection of a combination of a gonadotropin-releasing hormone (GnRH) agonist and a Dopamine Antagonist. We have named this formulation AMPHIPLEX, which is derived from the combination of the words amphibian and amplexus. This name refers to the specific reproductive behavior of frogs when the male mounts and clasps the female to induce ovulation and to fertilize the eggs as they are laid. We describe the use of the method and demonstrate its applicability for captive breeding in 3 different anuran families. We tested several combinations of GnRH agonists with Dopamine Antagonists using Lithobates pipiens. The combination of des-Gly10, D-Ala6, Pro-LHRH (0.4 microrams/g body weight) and metoclopramide (10 micrograms/g BWt. MET) was most effective. It was used in-season, after short-term captivity and in frogs artificially hibernated under laboratory conditions. The AMPHIPLEX method was also effective in 3 Argentinian frogs, Ceratophrys ornata, Ceratophrys cranwelli and Odontophrynus americanus. Our approach offers some advantages over other hormonally-based techniques. Both sexes are injected only once and at the same time, reducing handling stress. AMPHIPLEX is a new reproductive management tool for captive breeding in Anura.
Jacqui Wignall - One of the best experts on this subject based on the ideXlab platform.
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Hormonal induction of spawning in 4 species of frogs by coinjection with a gonadotropin-releasing hormone agonist and a Dopamine Antagonist
Reproductive Biology and Endocrinology, 2010Co-Authors: Vance L Trudeau, Gustavo M Somoza, Guillermo S Natale, Bruce Pauli, Jacqui Wignall, Paula Jackman, Ken Doe, Fredrick W SchuelerAbstract:Background It is well known that many anurans do not reproduce easily in captivity. Some methods are based on administration of mammalian hormones such as human chorionic gonadotropin, which are not effective in many frogs. There is a need for simple, cost-effective alternative techniques to induce spawning. Methods Our new method is based on the injection of a combination of a gonadotropin-releasing hormone (GnRH) agonist and a Dopamine Antagonist. We have named this formulation AMPHIPLEX, which is derived from the combination of the words amphibian and amplexus. This name refers to the specific reproductive behavior of frogs when the male mounts and clasps the female to induce ovulation and to fertilize the eggs as they are laid. Results We describe the use of the method and demonstrate its applicability for captive breeding in 3 different anuran families. We tested several combinations of GnRH agonists with Dopamine Antagonists using Lithobates pipiens. The combination of des-Gly^10, D-Ala^6, Pro-LHRH (0.4 microrams/g body weight) and metoclopramide (10 micrograms/g BWt. MET) was most effective. It was used in-season, after short-term captivity and in frogs artificially hibernated under laboratory conditions. The AMPHIPLEX method was also effective in 3 Argentinian frogs, Ceratophrys ornata , Ceratophrys cranwelli and Odontophrynus americanus . Conclusion Our approach offers some advantages over other hormonally-based techniques. Both sexes are injected only once and at the same time, reducing handling stress. AMPHIPLEX is a new reproductive management tool for captive breeding in Anura.
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hormonal induction of spawning in 4 species of frogs by coinjection with a gonadotropin releasing hormone agonist and a Dopamine Antagonist
Reproductive Biology and Endocrinology, 2010Co-Authors: Vance L Trudeau, Gustavo M Somoza, Guillermo S Natale, Jacqui Wignall, Paula Jackman, Ken Doe, Bruce D Pauli, Fredrick W SchuelerAbstract:It is well known that many anurans do not reproduce easily in captivity. Some methods are based on administration of mammalian hormones such as human chorionic gonadotropin, which are not effective in many frogs. There is a need for simple, cost-effective alternative techniques to induce spawning. Our new method is based on the injection of a combination of a gonadotropin-releasing hormone (GnRH) agonist and a Dopamine Antagonist. We have named this formulation AMPHIPLEX, which is derived from the combination of the words amphibian and amplexus. This name refers to the specific reproductive behavior of frogs when the male mounts and clasps the female to induce ovulation and to fertilize the eggs as they are laid. We describe the use of the method and demonstrate its applicability for captive breeding in 3 different anuran families. We tested several combinations of GnRH agonists with Dopamine Antagonists using Lithobates pipiens. The combination of des-Gly10, D-Ala6, Pro-LHRH (0.4 microrams/g body weight) and metoclopramide (10 micrograms/g BWt. MET) was most effective. It was used in-season, after short-term captivity and in frogs artificially hibernated under laboratory conditions. The AMPHIPLEX method was also effective in 3 Argentinian frogs, Ceratophrys ornata, Ceratophrys cranwelli and Odontophrynus americanus. Our approach offers some advantages over other hormonally-based techniques. Both sexes are injected only once and at the same time, reducing handling stress. AMPHIPLEX is a new reproductive management tool for captive breeding in Anura.
Vance L Trudeau - One of the best experts on this subject based on the ideXlab platform.
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Hormonal induction of spawning in 4 species of frogs by coinjection with a gonadotropin-releasing hormone agonist and a Dopamine Antagonist
Reproductive Biology and Endocrinology, 2010Co-Authors: Vance L Trudeau, Gustavo M Somoza, Guillermo S Natale, Bruce Pauli, Jacqui Wignall, Paula Jackman, Ken Doe, Fredrick W SchuelerAbstract:Background It is well known that many anurans do not reproduce easily in captivity. Some methods are based on administration of mammalian hormones such as human chorionic gonadotropin, which are not effective in many frogs. There is a need for simple, cost-effective alternative techniques to induce spawning. Methods Our new method is based on the injection of a combination of a gonadotropin-releasing hormone (GnRH) agonist and a Dopamine Antagonist. We have named this formulation AMPHIPLEX, which is derived from the combination of the words amphibian and amplexus. This name refers to the specific reproductive behavior of frogs when the male mounts and clasps the female to induce ovulation and to fertilize the eggs as they are laid. Results We describe the use of the method and demonstrate its applicability for captive breeding in 3 different anuran families. We tested several combinations of GnRH agonists with Dopamine Antagonists using Lithobates pipiens. The combination of des-Gly^10, D-Ala^6, Pro-LHRH (0.4 microrams/g body weight) and metoclopramide (10 micrograms/g BWt. MET) was most effective. It was used in-season, after short-term captivity and in frogs artificially hibernated under laboratory conditions. The AMPHIPLEX method was also effective in 3 Argentinian frogs, Ceratophrys ornata , Ceratophrys cranwelli and Odontophrynus americanus . Conclusion Our approach offers some advantages over other hormonally-based techniques. Both sexes are injected only once and at the same time, reducing handling stress. AMPHIPLEX is a new reproductive management tool for captive breeding in Anura.
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hormonal induction of spawning in 4 species of frogs by coinjection with a gonadotropin releasing hormone agonist and a Dopamine Antagonist
Reproductive Biology and Endocrinology, 2010Co-Authors: Vance L Trudeau, Gustavo M Somoza, Guillermo S Natale, Jacqui Wignall, Paula Jackman, Ken Doe, Bruce D Pauli, Fredrick W SchuelerAbstract:It is well known that many anurans do not reproduce easily in captivity. Some methods are based on administration of mammalian hormones such as human chorionic gonadotropin, which are not effective in many frogs. There is a need for simple, cost-effective alternative techniques to induce spawning. Our new method is based on the injection of a combination of a gonadotropin-releasing hormone (GnRH) agonist and a Dopamine Antagonist. We have named this formulation AMPHIPLEX, which is derived from the combination of the words amphibian and amplexus. This name refers to the specific reproductive behavior of frogs when the male mounts and clasps the female to induce ovulation and to fertilize the eggs as they are laid. We describe the use of the method and demonstrate its applicability for captive breeding in 3 different anuran families. We tested several combinations of GnRH agonists with Dopamine Antagonists using Lithobates pipiens. The combination of des-Gly10, D-Ala6, Pro-LHRH (0.4 microrams/g body weight) and metoclopramide (10 micrograms/g BWt. MET) was most effective. It was used in-season, after short-term captivity and in frogs artificially hibernated under laboratory conditions. The AMPHIPLEX method was also effective in 3 Argentinian frogs, Ceratophrys ornata, Ceratophrys cranwelli and Odontophrynus americanus. Our approach offers some advantages over other hormonally-based techniques. Both sexes are injected only once and at the same time, reducing handling stress. AMPHIPLEX is a new reproductive management tool for captive breeding in Anura.
Aaron Ettenberg - One of the best experts on this subject based on the ideXlab platform.
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haloperidol does not affect motivational processes in an operant runway model of food seeking behavior
Behavioral Neuroscience, 1998Co-Authors: Krista Mcfarland, Aaron EttenbergAbstract:The present experiment examined the effects of Dopamine receptor antagonism on subjects' motivation to seek food. Rats were trained to discriminate between 2 olfactory cues predicting either the presence (S+) or absence (S-) of food reinforcement in the goal box of a straight-arm runway. Rats learned to traverse the alley quickly when presented with the S+ and much more slowly when presented with the S-. Haloperidol pretreatment was unable to alter this pattern of behavior (i.e., rats still ran quickly when presented with the scent that predicted food availability). Thus, it seems that the same Dopamine Antagonist treatments that have been shown to disrupt food reinforcement do not prevent the food-seeking behavior produced by presentation of food-predictive cues.
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opposite effects of prefrontal cortex and nucleus accumbens infusions of flupenthixol on stimulant induced locomotion and brain stimulation reward
Brain Research, 1992Co-Authors: Christine L. Duvauchelle, Mark Levitin, Leigh A Macconell, Linda K Lee, Aaron EttenbergAbstract:Ventral tegmental area (VTA) stimulation produced conditioned place preferences for stimulation-paired environments the magnitudes of which were dose-dependently reduced by systemic application of the Dopamine Antagonist, haloperidol (0.0, 0.15, 0.3 mg/kg). Bilateral microinjections of cis-flupenthixol (FLU) into the nucleus accumbens (0.0, 1.0, 5.0 or 10.0 μg) also resulted in reductions in the size of stimulation-induced place preferences was either unaffected (1.0 and 5.0 μg groups) or slightly increased (10 μg group) and amphetamine-stimulated hyperlocomotion was dose-dependently potentiated. These behavioral findings suggest a Dopamine-mediated modulatory role for the PFC over reward relevant elements within the nucleus accumbens.
Ken Doe - One of the best experts on this subject based on the ideXlab platform.
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Hormonal induction of spawning in 4 species of frogs by coinjection with a gonadotropin-releasing hormone agonist and a Dopamine Antagonist
Reproductive Biology and Endocrinology, 2010Co-Authors: Vance L Trudeau, Gustavo M Somoza, Guillermo S Natale, Bruce Pauli, Jacqui Wignall, Paula Jackman, Ken Doe, Fredrick W SchuelerAbstract:Background It is well known that many anurans do not reproduce easily in captivity. Some methods are based on administration of mammalian hormones such as human chorionic gonadotropin, which are not effective in many frogs. There is a need for simple, cost-effective alternative techniques to induce spawning. Methods Our new method is based on the injection of a combination of a gonadotropin-releasing hormone (GnRH) agonist and a Dopamine Antagonist. We have named this formulation AMPHIPLEX, which is derived from the combination of the words amphibian and amplexus. This name refers to the specific reproductive behavior of frogs when the male mounts and clasps the female to induce ovulation and to fertilize the eggs as they are laid. Results We describe the use of the method and demonstrate its applicability for captive breeding in 3 different anuran families. We tested several combinations of GnRH agonists with Dopamine Antagonists using Lithobates pipiens. The combination of des-Gly^10, D-Ala^6, Pro-LHRH (0.4 microrams/g body weight) and metoclopramide (10 micrograms/g BWt. MET) was most effective. It was used in-season, after short-term captivity and in frogs artificially hibernated under laboratory conditions. The AMPHIPLEX method was also effective in 3 Argentinian frogs, Ceratophrys ornata , Ceratophrys cranwelli and Odontophrynus americanus . Conclusion Our approach offers some advantages over other hormonally-based techniques. Both sexes are injected only once and at the same time, reducing handling stress. AMPHIPLEX is a new reproductive management tool for captive breeding in Anura.
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hormonal induction of spawning in 4 species of frogs by coinjection with a gonadotropin releasing hormone agonist and a Dopamine Antagonist
Reproductive Biology and Endocrinology, 2010Co-Authors: Vance L Trudeau, Gustavo M Somoza, Guillermo S Natale, Jacqui Wignall, Paula Jackman, Ken Doe, Bruce D Pauli, Fredrick W SchuelerAbstract:It is well known that many anurans do not reproduce easily in captivity. Some methods are based on administration of mammalian hormones such as human chorionic gonadotropin, which are not effective in many frogs. There is a need for simple, cost-effective alternative techniques to induce spawning. Our new method is based on the injection of a combination of a gonadotropin-releasing hormone (GnRH) agonist and a Dopamine Antagonist. We have named this formulation AMPHIPLEX, which is derived from the combination of the words amphibian and amplexus. This name refers to the specific reproductive behavior of frogs when the male mounts and clasps the female to induce ovulation and to fertilize the eggs as they are laid. We describe the use of the method and demonstrate its applicability for captive breeding in 3 different anuran families. We tested several combinations of GnRH agonists with Dopamine Antagonists using Lithobates pipiens. The combination of des-Gly10, D-Ala6, Pro-LHRH (0.4 microrams/g body weight) and metoclopramide (10 micrograms/g BWt. MET) was most effective. It was used in-season, after short-term captivity and in frogs artificially hibernated under laboratory conditions. The AMPHIPLEX method was also effective in 3 Argentinian frogs, Ceratophrys ornata, Ceratophrys cranwelli and Odontophrynus americanus. Our approach offers some advantages over other hormonally-based techniques. Both sexes are injected only once and at the same time, reducing handling stress. AMPHIPLEX is a new reproductive management tool for captive breeding in Anura.