Drug Analysis

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The Experts below are selected from a list of 303 Experts worldwide ranked by ideXlab platform

Sabine Bladt - One of the best experts on this subject based on the ideXlab platform.

Hildebert Wagner - One of the best experts on this subject based on the ideXlab platform.

Shi-xin He - One of the best experts on this subject based on the ideXlab platform.

  • Research Progress of Raman Spectroscopy in Drug Analysis
    Aaps Pharmscitech, 2018
    Co-Authors: Wen-ting Wang, Hua Zhang, Yuan Yuan, Shi-xin He
    Abstract:

    : Raman spectroscopy is a spectroscopic Analysis technique that enables rapid qualitative and quantitative detection based on inelastic collision and Raman scattering intensity. This review detailed the generation principle, instrument composition, influencing factors, and common classifications of Raman spectrum. Furthermore, it summarized and forecast the research progress of Raman spectroscopy in the field of Drug Analysis simultaneously over the past decade, including the identification of active pharmaceutical ingredients (APIs), qualitative and quantitative studies of pharmaceutical preparations, detection of illicit Drugs, the identification of Chinese herbal medicines, and the combination with other technologies. The development of Raman spectroscopy in other fields is additionally summarized.

Isaac O Kibwage - One of the best experts on this subject based on the ideXlab platform.

  • Drug Quality Control in Kenya: Observation in the Drug Analysis and Research Unit During the Period 2001-2005
    The East and Central African Journal of Pharmaceutical Sciences, 2009
    Co-Authors: Grace N. Thoithi, K.o. Abuga, Jm Nguyo, Jk Ngugi, Ok King’ondu, Hn Mugo, Gg Mukindia, Isaac O Kibwage
    Abstract:

    During the five-year period January 2001 to December 2005, the Drug Analysis and Research Unit received and analyzed 394 Drug samples. Samples were received from regulatory authorities, local industry, non-governmental organizations, hospitals and private practitioners. The samples analyzed constituted 37.8 % locally manufactured and 62.2 % imported products. In contrast to previous years when failure rates of over 20 % were recorded, the overall rate of failure to comply with compendial quality specifications was 6.1 %, comprising of 8.7 % locally manufactured and 4.5 % imported Drugs.

  • Quality of antiretroviral Drugs analyzed in the Drug Analysis and research unit during 2000--2003
    The East and Central African Journal of Pharmaceutical Sciences, 2005
    Co-Authors: K.o. Abuga, Pm Mwagiru, Grace N. Thoithi, Jm Nguyo, Jk Ngugi, Ok King’ondu, Hn Mugo, Isaac O Kibwage
    Abstract:

    During the period 2000-2003 the Drug Analysis and Research Unit received and analyzed 33 samples of antiretroviral Drugs. Locally manufactured products accounted for 57.6 % of the samples, while the imported Drugs constituted 42.4 %. The Drugs consisted of single, double and triple component preparations. They were subjected to the identity, assay and dissolution tests. 30 samples (90.9 %) complied with compedial specifications for these tests, while 3 failed. The results obtained show that manufacture of quality generic antiretroviral Drugs is achievable. Key Words: Antiretroviral, assay, dissolution, nucleoside reverse-transcriptase inhibitor East & Central African Journal of Pharmaceutical Sciences Vol.6(1) 2003: 20-23

Hn Mugo - One of the best experts on this subject based on the ideXlab platform.

  • Quality performance of Drugs analyzed in the Drug Analysis and Research unit (DARU) during the period 2006-2010.
    The East and Central African Journal of Pharmaceutical Sciences, 2020
    Co-Authors: K.o. Abuga, Grace N. Thoithi, Jm Nguyo, Ok King’ondu, Beatrice K Amugune, S.n. Ndwigah, Fn Kamau, Jo Ogeto, Alex O. Okaru, Hn Mugo
    Abstract:

    During the period 2006-2010, the Drug Analysis and Research Unit analyzed 583 samples. The samples comprised 50.6% local and 49.4% imported products. Samples were subjected to compendial or in-house specifications. The failure rate was 12.2% for local products and 14.2% for imports.  Antibacterial products recorded the highest failure rate (21.6%) while  anticancers and Drugs acting on the gastrointestinal, respiratory and  reproductive systems all passed in the tests performed. The failure rate for antiprotozoals, antimalarials, antifungals, anthelminthics and analgesics was 14.3%, 12.5%, 11.8%, 8.9% and 11.5%, respectively. Key words : DARU, Drug product, assay, dissolution, antimicrobial, antimalarial

  • Drug Quality Control in Kenya: Observation in the Drug Analysis and Research Unit During the Period 2001-2005
    The East and Central African Journal of Pharmaceutical Sciences, 2009
    Co-Authors: Grace N. Thoithi, K.o. Abuga, Jm Nguyo, Jk Ngugi, Ok King’ondu, Hn Mugo, Gg Mukindia, Isaac O Kibwage
    Abstract:

    During the five-year period January 2001 to December 2005, the Drug Analysis and Research Unit received and analyzed 394 Drug samples. Samples were received from regulatory authorities, local industry, non-governmental organizations, hospitals and private practitioners. The samples analyzed constituted 37.8 % locally manufactured and 62.2 % imported products. In contrast to previous years when failure rates of over 20 % were recorded, the overall rate of failure to comply with compendial quality specifications was 6.1 %, comprising of 8.7 % locally manufactured and 4.5 % imported Drugs.

  • Quality of antiretroviral Drugs analyzed in the Drug Analysis and research unit during 2000--2003
    The East and Central African Journal of Pharmaceutical Sciences, 2005
    Co-Authors: K.o. Abuga, Pm Mwagiru, Grace N. Thoithi, Jm Nguyo, Jk Ngugi, Ok King’ondu, Hn Mugo, Isaac O Kibwage
    Abstract:

    During the period 2000-2003 the Drug Analysis and Research Unit received and analyzed 33 samples of antiretroviral Drugs. Locally manufactured products accounted for 57.6 % of the samples, while the imported Drugs constituted 42.4 %. The Drugs consisted of single, double and triple component preparations. They were subjected to the identity, assay and dissolution tests. 30 samples (90.9 %) complied with compedial specifications for these tests, while 3 failed. The results obtained show that manufacture of quality generic antiretroviral Drugs is achievable. Key Words: Antiretroviral, assay, dissolution, nucleoside reverse-transcriptase inhibitor East & Central African Journal of Pharmaceutical Sciences Vol.6(1) 2003: 20-23

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