Drug Delivery System

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Zhong Lin Wang - One of the best experts on this subject based on the ideXlab platform.

  • a self powered implantable Drug Delivery System using biokinetic energy
    Advanced Materials, 2017
    Co-Authors: Peiyi Song, Shuangyang Kuang, Nishtha Panwar, Guang Yang, Danny Jian Hang Tng, Swee Chuan Tjin, Maszenan Bin Abdul Majid, Guang Zhu, Kentye Yong, Zhong Lin Wang
    Abstract:

    The first triboelectric-nanogenerator (TENG)-based self-powered implantable Drug-Delivery System is presented. Pumping flow rates from 5.3 to 40 µL min-1 under different rotating speeds of the TENG are realized. The implantable Drug-Delivery System can be powered with a TENG device rotated by human hand motion. Ex vivo trans-sclera Drug Delivery in porcine eyes is demonstrated by utilizing the biokinetic energies of human hands.

Chandra Datta Sumi - One of the best experts on this subject based on the ideXlab platform.

  • Implantable microchip: The futuristic controlled Drug Delivery System
    Drug Delivery, 2016
    Co-Authors: Kumar Bishwajit Sutradhar, Chandra Datta Sumi
    Abstract:

    Abstract There is no doubt that controlled and pulsatile Drug Delivery System is an important challenge in medicine over the conventional Drug Delivery System in case of therapeutic efficacy. However, the conventional Drug Delivery Systems often offer a limited by their inability to Drug Delivery which consists of Systemic toxicity, narrow therapeutic window, complex dosing schedule for long term treatment etc. Therefore, there has been a search for the Drug Delivery System that exhibit broad enhancing activity for more Drugs with less complication. More recently, some elegant study has noted that, a new type of micro-electrochemical System or MEMS-based Drug Delivery Systems called microchip has been improved to overcome the problems related to conventional Drug Delivery. Moreover, micro-fabrication technology has enabled to develop the implantable controlled released microchip devices with improved Drug administration and patient compliance. In this article, we have presented an overview of the investigations on the feasibility and application of microchip as an advanced Drug Delivery System. Commercial manufacturing materials and methods, related other research works and current advancement of the microchips for controlled Drug Delivery have also been summarized.

Ramandeep Singh - One of the best experts on this subject based on the ideXlab platform.

  • A REVIEW ON TRANSDERMAL Drug Delivery System
    International journal of sciences, 2016
    Co-Authors: Satinder Kakkar, Pooja Rani, Ramandeep Singh
    Abstract:

    This article deals with the study of transdermal Drug Delivery System . Transdermal Drug Delivery System is the System in which the Delivery of the active ingredients of the Drug occurs through the skin. A transdermal patch is defined as medicated adhesive patch which is placed above the skin to deliver a specific dose of medication through the skin with a predetermined rate of release to reach into the bloodstream.This article includes study of transdermal Drug Delivery System regarding its advantages, disadvantages, mechanism of action, types, developments, components, methods, factors affecting transdermal Delivery, and its evaluation.

Peiyi Song - One of the best experts on this subject based on the ideXlab platform.

  • a self powered implantable Drug Delivery System using biokinetic energy
    Advanced Materials, 2017
    Co-Authors: Peiyi Song, Shuangyang Kuang, Nishtha Panwar, Guang Yang, Danny Jian Hang Tng, Swee Chuan Tjin, Maszenan Bin Abdul Majid, Guang Zhu, Kentye Yong, Zhong Lin Wang
    Abstract:

    The first triboelectric-nanogenerator (TENG)-based self-powered implantable Drug-Delivery System is presented. Pumping flow rates from 5.3 to 40 µL min-1 under different rotating speeds of the TENG are realized. The implantable Drug-Delivery System can be powered with a TENG device rotated by human hand motion. Ex vivo trans-sclera Drug Delivery in porcine eyes is demonstrated by utilizing the biokinetic energies of human hands.

Kumar Bishwajit Sutradhar - One of the best experts on this subject based on the ideXlab platform.

  • Implantable microchip: The futuristic controlled Drug Delivery System
    Drug Delivery, 2016
    Co-Authors: Kumar Bishwajit Sutradhar, Chandra Datta Sumi
    Abstract:

    Abstract There is no doubt that controlled and pulsatile Drug Delivery System is an important challenge in medicine over the conventional Drug Delivery System in case of therapeutic efficacy. However, the conventional Drug Delivery Systems often offer a limited by their inability to Drug Delivery which consists of Systemic toxicity, narrow therapeutic window, complex dosing schedule for long term treatment etc. Therefore, there has been a search for the Drug Delivery System that exhibit broad enhancing activity for more Drugs with less complication. More recently, some elegant study has noted that, a new type of micro-electrochemical System or MEMS-based Drug Delivery Systems called microchip has been improved to overcome the problems related to conventional Drug Delivery. Moreover, micro-fabrication technology has enabled to develop the implantable controlled released microchip devices with improved Drug administration and patient compliance. In this article, we have presented an overview of the investigations on the feasibility and application of microchip as an advanced Drug Delivery System. Commercial manufacturing materials and methods, related other research works and current advancement of the microchips for controlled Drug Delivery have also been summarized.