The Experts below are selected from a list of 23532 Experts worldwide ranked by ideXlab platform
Qing Zhang - One of the best experts on this subject based on the ideXlab platform.
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analysis of the positive rate of 4254 cases of covid 19 nucleic acid tests in different aites in wuhan china
Journal of Medical Virology, 2021Co-Authors: Kebin Deng, Ying Chen, Bo Tian, Qing ZhangAbstract:BACKGROUND: There's an outbreak of COVID-19 since December 2019, first in Wuhan. It has caused huge medical challenges to Hubei Province with currently more than 67 thousand confirmed cases till March 08, 2020. Identification, there is no clinically effective Drug. Isolation and masks are essential to limit human-to-human transmission initially. The nucleic acid test (NAT) of COVID-19 currently was the most reliable established laboratory diagnosis method in clinical. METHODS: From February 8th, 2020 to March 7th, 2020, 4254 cases were collected for analysis at six nucleic acid collection sites in the community medical team of Hubei Provincial Hospital of Traditional Chinese Medicine, which cover almost all groups who need NAT in Wuhan. Distribution of positive rates in different sites by genders, ages or occupations were compared. RESULTS: The positive rates of different sites from high to low were: hospital wards (24.71%) > fever clinics (16.57%) > nursing homes (5.51%) > Isolation hotels (5.30%) > rehabilitation stations (1.36%) > close contact sites (0.17%). The confirmed patients in Isolation hotels, hospital ward and fever clinical were mainly middle-aged and elderly, and most of them were women. The positive rate in Isolation hotels and fever clinics gradually decreased over time. There were no significant differences between genders among those six nucleic acid collection sites (P <0.05). CONCLUSIONS: The hospital wards have the highest positive rate; however, close contact sites have lowest one. Patients who are discharged from hospitals may still have potential risks. Middle-aged and older people remain the focus of epidemic prevention and control. This article is protected by copyright. All rights reserved.
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Analysis of the positive rate of 4254 cases of COVID-19 nucleic acid tests in different aites in Wuhan, China.
Journal of medical virology, 2020Co-Authors: Kebin Deng, Ying Chen, Bo Tian, Qing ZhangAbstract:BACKGROUND: There's an outbreak of COVID-19 since December 2019, first in Wuhan. It has caused huge medical challenges to Hubei Province with currently more than 67 thousand confirmed cases till March 08, 2020. Identification, there is no clinically effective Drug. Isolation and masks are essential to limit human-to-human transmission initially. The nucleic acid test (NAT) of COVID-19 currently was the most reliable established laboratory diagnosis method in clinical. METHODS: From February 8th, 2020 to March 7th, 2020, 4254 cases were collected for analysis at six nucleic acid collection sites in the community medical team of Hubei Provincial Hospital of Traditional Chinese Medicine, which cover almost all groups who need NAT in Wuhan. Distribution of positive rates in different sites by genders, ages or occupations were compared. RESULTS: The positive rates of different sites from high to low were: hospital wards (24.71%) > fever clinics (16.57%) > nursing homes (5.51%) > Isolation hotels (5.30%) > rehabilitation stations (1.36%) > close contact sites (0.17%). The confirmed patients in Isolation hotels, hospital ward and fever clinical were mainly middle-aged and elderly, and most of them were women. The positive rate in Isolation hotels and fever clinics gradually decreased over time. There were no significant differences between genders among those six nucleic acid collection sites (P
Kebin Deng - One of the best experts on this subject based on the ideXlab platform.
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analysis of the positive rate of 4254 cases of covid 19 nucleic acid tests in different aites in wuhan china
Journal of Medical Virology, 2021Co-Authors: Kebin Deng, Ying Chen, Bo Tian, Qing ZhangAbstract:BACKGROUND: There's an outbreak of COVID-19 since December 2019, first in Wuhan. It has caused huge medical challenges to Hubei Province with currently more than 67 thousand confirmed cases till March 08, 2020. Identification, there is no clinically effective Drug. Isolation and masks are essential to limit human-to-human transmission initially. The nucleic acid test (NAT) of COVID-19 currently was the most reliable established laboratory diagnosis method in clinical. METHODS: From February 8th, 2020 to March 7th, 2020, 4254 cases were collected for analysis at six nucleic acid collection sites in the community medical team of Hubei Provincial Hospital of Traditional Chinese Medicine, which cover almost all groups who need NAT in Wuhan. Distribution of positive rates in different sites by genders, ages or occupations were compared. RESULTS: The positive rates of different sites from high to low were: hospital wards (24.71%) > fever clinics (16.57%) > nursing homes (5.51%) > Isolation hotels (5.30%) > rehabilitation stations (1.36%) > close contact sites (0.17%). The confirmed patients in Isolation hotels, hospital ward and fever clinical were mainly middle-aged and elderly, and most of them were women. The positive rate in Isolation hotels and fever clinics gradually decreased over time. There were no significant differences between genders among those six nucleic acid collection sites (P <0.05). CONCLUSIONS: The hospital wards have the highest positive rate; however, close contact sites have lowest one. Patients who are discharged from hospitals may still have potential risks. Middle-aged and older people remain the focus of epidemic prevention and control. This article is protected by copyright. All rights reserved.
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Analysis of the positive rate of 4254 cases of COVID-19 nucleic acid tests in different aites in Wuhan, China.
Journal of medical virology, 2020Co-Authors: Kebin Deng, Ying Chen, Bo Tian, Qing ZhangAbstract:BACKGROUND: There's an outbreak of COVID-19 since December 2019, first in Wuhan. It has caused huge medical challenges to Hubei Province with currently more than 67 thousand confirmed cases till March 08, 2020. Identification, there is no clinically effective Drug. Isolation and masks are essential to limit human-to-human transmission initially. The nucleic acid test (NAT) of COVID-19 currently was the most reliable established laboratory diagnosis method in clinical. METHODS: From February 8th, 2020 to March 7th, 2020, 4254 cases were collected for analysis at six nucleic acid collection sites in the community medical team of Hubei Provincial Hospital of Traditional Chinese Medicine, which cover almost all groups who need NAT in Wuhan. Distribution of positive rates in different sites by genders, ages or occupations were compared. RESULTS: The positive rates of different sites from high to low were: hospital wards (24.71%) > fever clinics (16.57%) > nursing homes (5.51%) > Isolation hotels (5.30%) > rehabilitation stations (1.36%) > close contact sites (0.17%). The confirmed patients in Isolation hotels, hospital ward and fever clinical were mainly middle-aged and elderly, and most of them were women. The positive rate in Isolation hotels and fever clinics gradually decreased over time. There were no significant differences between genders among those six nucleic acid collection sites (P
John J. Walsh - One of the best experts on this subject based on the ideXlab platform.
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nature s cholesterol lowering Drug Isolation and structure elucidation of lovastatin from red yeast rice containing dietary supplements
Journal of Chemical Education, 2012Co-Authors: Maisarah Mohd Nazri, Farah D. Samat, Pierce V. Kavanagh, John J. WalshAbstract:Red yeast rice, produced by fermenting the fungus, Monascus purpureus, on rice (Oryza sativa L. gramineae), is commonly used as a dietary supplement. It contains lovastatin, a member of the statin family of compounds, and is licensed for use as a cholesterol-lowering agent. This experiment involves the Isolation and structure elucidation of lovastatin from red yeast rice-containing dietary supplements. Isolation of the neutral constituents in red yeast rice can be performed using either ether or ethyl acetate as extracting solvent, and flash column chromatography combined with thin-layer chromatography is used to isolate lovastatin in pure form from the extract. During the course of the experiment, the students isolate lovastatin with an average recovery of 0.31%. IR, MS, and detailed NMR spectroscopic analyses confirm the structure of lovastatin. The experiment can be completed over two, 3-h laboratory sessions and is suitable for students at the third- or fourth-year undergraduate level. Overall the exp...
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Nature’s Cholesterol-Lowering Drug: Isolation and Structure Elucidation of Lovastatin from Red Yeast Rice-Containing Dietary Supplements
Journal of Chemical Education, 2011Co-Authors: Maisarah Mohd Nazri, Farah D. Samat, Pierce V. Kavanagh, John J. WalshAbstract:Red yeast rice, produced by fermenting the fungus, Monascus purpureus, on rice (Oryza sativa L. gramineae), is commonly used as a dietary supplement. It contains lovastatin, a member of the statin family of compounds, and is licensed for use as a cholesterol-lowering agent. This experiment involves the Isolation and structure elucidation of lovastatin from red yeast rice-containing dietary supplements. Isolation of the neutral constituents in red yeast rice can be performed using either ether or ethyl acetate as extracting solvent, and flash column chromatography combined with thin-layer chromatography is used to isolate lovastatin in pure form from the extract. During the course of the experiment, the students isolate lovastatin with an average recovery of 0.31%. IR, MS, and detailed NMR spectroscopic analyses confirm the structure of lovastatin. The experiment can be completed over two, 3-h laboratory sessions and is suitable for students at the third- or fourth-year undergraduate level. Overall the exp...
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nature s anti alzheimer s Drug Isolation and structure elucidation of galantamine from leucojum aestivum
Journal of Chemical Education, 2010Co-Authors: Catherine M. Halpin, Ciara Reilly, John J. WalshAbstract:The discovery that galantamine penetrates the blood−brain barrier has led to its clinical use in the treatment of choline-deficiency conditions in the brain, such as Alzheimer’s disease. This experiment involves the Isolation and structure elucidation of galantamine from Leucojum aestivum. Isolation of the alkaloid constituents in L. aestivum is performed using an acidic solvent extraction system, and flash-column chromatography combined with thin-layer chromatography is used to isolate galantamine in pure form from the extract. During the course of the experiment, the students isolate galantamine with an average recovery of 0.15%. IR, MS, 1D-NMR, and 2D-NMR spectra confirm the structure of galantamine. The experiment can be completed over two, 3-h laboratory sessions and is suitable for upper-level undergraduate students. The experiment acquaints the students with the techniques required to isolate and complete structural elucidation studies on natural products.
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Nature’s Anti-Alzheimer’s Drug: Isolation and Structure Elucidation of Galantamine from Leucojum aestivum
Journal of Chemical Education, 2010Co-Authors: Catherine M. Halpin, Ciara Reilly, John J. WalshAbstract:The discovery that galantamine penetrates the blood−brain barrier has led to its clinical use in the treatment of choline-deficiency conditions in the brain, such as Alzheimer’s disease. This experiment involves the Isolation and structure elucidation of galantamine from Leucojum aestivum. Isolation of the alkaloid constituents in L. aestivum is performed using an acidic solvent extraction system, and flash-column chromatography combined with thin-layer chromatography is used to isolate galantamine in pure form from the extract. During the course of the experiment, the students isolate galantamine with an average recovery of 0.15%. IR, MS, 1D-NMR, and 2D-NMR spectra confirm the structure of galantamine. The experiment can be completed over two, 3-h laboratory sessions and is suitable for upper-level undergraduate students. The experiment acquaints the students with the techniques required to isolate and complete structural elucidation studies on natural products.
Bo Tian - One of the best experts on this subject based on the ideXlab platform.
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analysis of the positive rate of 4254 cases of covid 19 nucleic acid tests in different aites in wuhan china
Journal of Medical Virology, 2021Co-Authors: Kebin Deng, Ying Chen, Bo Tian, Qing ZhangAbstract:BACKGROUND: There's an outbreak of COVID-19 since December 2019, first in Wuhan. It has caused huge medical challenges to Hubei Province with currently more than 67 thousand confirmed cases till March 08, 2020. Identification, there is no clinically effective Drug. Isolation and masks are essential to limit human-to-human transmission initially. The nucleic acid test (NAT) of COVID-19 currently was the most reliable established laboratory diagnosis method in clinical. METHODS: From February 8th, 2020 to March 7th, 2020, 4254 cases were collected for analysis at six nucleic acid collection sites in the community medical team of Hubei Provincial Hospital of Traditional Chinese Medicine, which cover almost all groups who need NAT in Wuhan. Distribution of positive rates in different sites by genders, ages or occupations were compared. RESULTS: The positive rates of different sites from high to low were: hospital wards (24.71%) > fever clinics (16.57%) > nursing homes (5.51%) > Isolation hotels (5.30%) > rehabilitation stations (1.36%) > close contact sites (0.17%). The confirmed patients in Isolation hotels, hospital ward and fever clinical were mainly middle-aged and elderly, and most of them were women. The positive rate in Isolation hotels and fever clinics gradually decreased over time. There were no significant differences between genders among those six nucleic acid collection sites (P <0.05). CONCLUSIONS: The hospital wards have the highest positive rate; however, close contact sites have lowest one. Patients who are discharged from hospitals may still have potential risks. Middle-aged and older people remain the focus of epidemic prevention and control. This article is protected by copyright. All rights reserved.
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Analysis of the positive rate of 4254 cases of COVID-19 nucleic acid tests in different aites in Wuhan, China.
Journal of medical virology, 2020Co-Authors: Kebin Deng, Ying Chen, Bo Tian, Qing ZhangAbstract:BACKGROUND: There's an outbreak of COVID-19 since December 2019, first in Wuhan. It has caused huge medical challenges to Hubei Province with currently more than 67 thousand confirmed cases till March 08, 2020. Identification, there is no clinically effective Drug. Isolation and masks are essential to limit human-to-human transmission initially. The nucleic acid test (NAT) of COVID-19 currently was the most reliable established laboratory diagnosis method in clinical. METHODS: From February 8th, 2020 to March 7th, 2020, 4254 cases were collected for analysis at six nucleic acid collection sites in the community medical team of Hubei Provincial Hospital of Traditional Chinese Medicine, which cover almost all groups who need NAT in Wuhan. Distribution of positive rates in different sites by genders, ages or occupations were compared. RESULTS: The positive rates of different sites from high to low were: hospital wards (24.71%) > fever clinics (16.57%) > nursing homes (5.51%) > Isolation hotels (5.30%) > rehabilitation stations (1.36%) > close contact sites (0.17%). The confirmed patients in Isolation hotels, hospital ward and fever clinical were mainly middle-aged and elderly, and most of them were women. The positive rate in Isolation hotels and fever clinics gradually decreased over time. There were no significant differences between genders among those six nucleic acid collection sites (P
Ying Chen - One of the best experts on this subject based on the ideXlab platform.
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analysis of the positive rate of 4254 cases of covid 19 nucleic acid tests in different aites in wuhan china
Journal of Medical Virology, 2021Co-Authors: Kebin Deng, Ying Chen, Bo Tian, Qing ZhangAbstract:BACKGROUND: There's an outbreak of COVID-19 since December 2019, first in Wuhan. It has caused huge medical challenges to Hubei Province with currently more than 67 thousand confirmed cases till March 08, 2020. Identification, there is no clinically effective Drug. Isolation and masks are essential to limit human-to-human transmission initially. The nucleic acid test (NAT) of COVID-19 currently was the most reliable established laboratory diagnosis method in clinical. METHODS: From February 8th, 2020 to March 7th, 2020, 4254 cases were collected for analysis at six nucleic acid collection sites in the community medical team of Hubei Provincial Hospital of Traditional Chinese Medicine, which cover almost all groups who need NAT in Wuhan. Distribution of positive rates in different sites by genders, ages or occupations were compared. RESULTS: The positive rates of different sites from high to low were: hospital wards (24.71%) > fever clinics (16.57%) > nursing homes (5.51%) > Isolation hotels (5.30%) > rehabilitation stations (1.36%) > close contact sites (0.17%). The confirmed patients in Isolation hotels, hospital ward and fever clinical were mainly middle-aged and elderly, and most of them were women. The positive rate in Isolation hotels and fever clinics gradually decreased over time. There were no significant differences between genders among those six nucleic acid collection sites (P <0.05). CONCLUSIONS: The hospital wards have the highest positive rate; however, close contact sites have lowest one. Patients who are discharged from hospitals may still have potential risks. Middle-aged and older people remain the focus of epidemic prevention and control. This article is protected by copyright. All rights reserved.
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Analysis of the positive rate of 4254 cases of COVID-19 nucleic acid tests in different aites in Wuhan, China.
Journal of medical virology, 2020Co-Authors: Kebin Deng, Ying Chen, Bo Tian, Qing ZhangAbstract:BACKGROUND: There's an outbreak of COVID-19 since December 2019, first in Wuhan. It has caused huge medical challenges to Hubei Province with currently more than 67 thousand confirmed cases till March 08, 2020. Identification, there is no clinically effective Drug. Isolation and masks are essential to limit human-to-human transmission initially. The nucleic acid test (NAT) of COVID-19 currently was the most reliable established laboratory diagnosis method in clinical. METHODS: From February 8th, 2020 to March 7th, 2020, 4254 cases were collected for analysis at six nucleic acid collection sites in the community medical team of Hubei Provincial Hospital of Traditional Chinese Medicine, which cover almost all groups who need NAT in Wuhan. Distribution of positive rates in different sites by genders, ages or occupations were compared. RESULTS: The positive rates of different sites from high to low were: hospital wards (24.71%) > fever clinics (16.57%) > nursing homes (5.51%) > Isolation hotels (5.30%) > rehabilitation stations (1.36%) > close contact sites (0.17%). The confirmed patients in Isolation hotels, hospital ward and fever clinical were mainly middle-aged and elderly, and most of them were women. The positive rate in Isolation hotels and fever clinics gradually decreased over time. There were no significant differences between genders among those six nucleic acid collection sites (P
