The Experts below are selected from a list of 3120 Experts worldwide ranked by ideXlab platform
Chen Xiao-li - One of the best experts on this subject based on the ideXlab platform.
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The Diagnosis of primary malignant Tumors of the Duodenum Tumor
Chinese Journal of Medicine, 2006Co-Authors: Chen Xiao-liAbstract:Objective To rise the diagnosis rate of primary duodenal malignances through analyzing its clinical characteristic and diagnosis.Methods The clinical data of 81 patients with primary malignant duodenal neoplasm from 1990 to 2002 were analyzed respectively in West China Hospital of Sichuan University.Results According to the locations of the Tumors,the Tumors above,around and below the duodenal papilla accounted for 16%,78% and 6% respectively.The common clinical manifestations were epigastralgia,obstructive jaundice,upper alimentary tract bleeding,abdomen mass and weight loss.The diagnosis rate of preoperation was 80%.Surgery was curative in 54 patients and palliative in 27 patients.3-and 5-years survival for the radical resection was 36% and 21% respectively.Conclusion The clinical manifestation of this patients is upper digestive tract symptom,biliary tract obstruction or haemorrhage,and the patients in different locations have their own characters relatively.Combination of duodenoscope and computer tomography imaging can improve the preoperative diagnosis rate.
Huang Jian-min - One of the best experts on this subject based on the ideXlab platform.
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Image analysis of leiomyosarcoma in descending Duodenum
Chinese Journal of Medical Imaging Technology, 2004Co-Authors: Huang Jian-minAbstract:Objects To evaluate different radiological methods in diagnosis of leimyosarcoma in descending Duodenum. Methods To analyze the radiological imaging of 7 cases which post operation pathology is leimyosarcoma in descending Duodenum. Results Barium study (gastro-intestinal) and CT scan are sensitive in detect extraluminal type of Duodenum Tumor and B type ultrasound, endoscopy are less valuable. Conclusion Barium study is the standard investigation for the diagnosis and detecting Duodenum Tumor, while CT is helpful in making correct diagnosis and clinical treatment.
Ronald L Prior - One of the best experts on this subject based on the ideXlab platform.
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Lack of efficacy of blueberry in nutritional prevention of azoxymethane-initiated cancers of rat small intestine and colon
BMC Gastroenterology, 2009Co-Authors: Frank A Simmen, Julie A Frank, Rijin Xiao, Leah J Hennings, Ronald L PriorAbstract:Background Blueberries may lower relative risk for cancers of the gastrointestinal tract. Previous work indicated an inhibitory effect of consumed blueberry (BB) on formation of aberrant crypt foci (ACF) in colons of male Fisher F344 rats (inbred strain). However, effects of BB on colon Tumors and in both genders are unknown. Methods We examined efficacy of BB in inhibition of azoxymethane (AOM)-induced colon ACF and intestine Tumors in male and female Sprague-Dawley rats (outbred strain). Pregnant rats were fed a diet with or without 10% BB powder; progeny were weaned to the same diet as their dam and received AOM as young adults. Results Male and female rats on control diet had similar numbers of ACF at 6 weeks after AOM administration. BB increased ( P < 0.05) ACF numbers within the distal colon of female but not male rats. There was a significant ( P < 0.05) diet by gender interaction with respect to total colon ACF number. Colon and Duodenum Tumor incidences were less in females than males at 17 weeks after AOM. BB tended (0.1 > P > 0.05) to reduce overall gastrointestinal tract Tumor incidence in males, however, Tumor incidence in females was unaffected ( P > 0.1) by BB. There was a tendency (0.1 > P > 0.05) for fewer adenocarcinomas (relative to total of adenomatous polyps plus adenocarcinomas) in colons of female than male Tumor-bearing rats; in small intestine, this gender difference was significant ( P < 0.05). BB favored ( P < 0.05) fewer adenocarcinomas and more adenomatous polyps (as a proportion of total Tumor number) in female rat small intestine. Conclusion Results did not indicate robust cancer-preventive effects of BB. Blueberry influenced ACF occurrence in distal colon and Tumor progression in Duodenum, in gender-specific fashion. Data indicate the potential for slowing Tumor progression (adenomatous polyp to adenocarcinoma) by BB.
Frank A Simmen - One of the best experts on this subject based on the ideXlab platform.
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Lack of efficacy of blueberry in nutritional prevention of azoxymethane-initiated cancers of rat small intestine and colon
BMC Gastroenterology, 2009Co-Authors: Frank A Simmen, Julie A Frank, Rijin Xiao, Leah J Hennings, Ronald L PriorAbstract:Background Blueberries may lower relative risk for cancers of the gastrointestinal tract. Previous work indicated an inhibitory effect of consumed blueberry (BB) on formation of aberrant crypt foci (ACF) in colons of male Fisher F344 rats (inbred strain). However, effects of BB on colon Tumors and in both genders are unknown. Methods We examined efficacy of BB in inhibition of azoxymethane (AOM)-induced colon ACF and intestine Tumors in male and female Sprague-Dawley rats (outbred strain). Pregnant rats were fed a diet with or without 10% BB powder; progeny were weaned to the same diet as their dam and received AOM as young adults. Results Male and female rats on control diet had similar numbers of ACF at 6 weeks after AOM administration. BB increased ( P < 0.05) ACF numbers within the distal colon of female but not male rats. There was a significant ( P < 0.05) diet by gender interaction with respect to total colon ACF number. Colon and Duodenum Tumor incidences were less in females than males at 17 weeks after AOM. BB tended (0.1 > P > 0.05) to reduce overall gastrointestinal tract Tumor incidence in males, however, Tumor incidence in females was unaffected ( P > 0.1) by BB. There was a tendency (0.1 > P > 0.05) for fewer adenocarcinomas (relative to total of adenomatous polyps plus adenocarcinomas) in colons of female than male Tumor-bearing rats; in small intestine, this gender difference was significant ( P < 0.05). BB favored ( P < 0.05) fewer adenocarcinomas and more adenomatous polyps (as a proportion of total Tumor number) in female rat small intestine. Conclusion Results did not indicate robust cancer-preventive effects of BB. Blueberry influenced ACF occurrence in distal colon and Tumor progression in Duodenum, in gender-specific fashion. Data indicate the potential for slowing Tumor progression (adenomatous polyp to adenocarcinoma) by BB.
Julie A Frank - One of the best experts on this subject based on the ideXlab platform.
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Lack of efficacy of blueberry in nutritional prevention of azoxymethane-initiated cancers of rat small intestine and colon
BMC Gastroenterology, 2009Co-Authors: Frank A Simmen, Julie A Frank, Rijin Xiao, Leah J Hennings, Ronald L PriorAbstract:Background Blueberries may lower relative risk for cancers of the gastrointestinal tract. Previous work indicated an inhibitory effect of consumed blueberry (BB) on formation of aberrant crypt foci (ACF) in colons of male Fisher F344 rats (inbred strain). However, effects of BB on colon Tumors and in both genders are unknown. Methods We examined efficacy of BB in inhibition of azoxymethane (AOM)-induced colon ACF and intestine Tumors in male and female Sprague-Dawley rats (outbred strain). Pregnant rats were fed a diet with or without 10% BB powder; progeny were weaned to the same diet as their dam and received AOM as young adults. Results Male and female rats on control diet had similar numbers of ACF at 6 weeks after AOM administration. BB increased ( P < 0.05) ACF numbers within the distal colon of female but not male rats. There was a significant ( P < 0.05) diet by gender interaction with respect to total colon ACF number. Colon and Duodenum Tumor incidences were less in females than males at 17 weeks after AOM. BB tended (0.1 > P > 0.05) to reduce overall gastrointestinal tract Tumor incidence in males, however, Tumor incidence in females was unaffected ( P > 0.1) by BB. There was a tendency (0.1 > P > 0.05) for fewer adenocarcinomas (relative to total of adenomatous polyps plus adenocarcinomas) in colons of female than male Tumor-bearing rats; in small intestine, this gender difference was significant ( P < 0.05). BB favored ( P < 0.05) fewer adenocarcinomas and more adenomatous polyps (as a proportion of total Tumor number) in female rat small intestine. Conclusion Results did not indicate robust cancer-preventive effects of BB. Blueberry influenced ACF occurrence in distal colon and Tumor progression in Duodenum, in gender-specific fashion. Data indicate the potential for slowing Tumor progression (adenomatous polyp to adenocarcinoma) by BB.
