The Experts below are selected from a list of 29898 Experts worldwide ranked by ideXlab platform
Jurgen J Futterer - One of the best experts on this subject based on the ideXlab platform.
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prostate cancer localization with Dynamic Contrast enhanced mr imaging and proton mr spectroscopic imaging
Radiology, 2006Co-Authors: Jurgen J Futterer, Arend Heerschap, Stijn W. T. P. J. Heijmink, Tom W. J. Scheenen, Jeroen Veltman, Paul F. M. Krabbe, Henkjan J Huisman, Alfred J Witjes, Jelle O BarentszAbstract:Purpose: To prospectively determine the accuracies of T2-weighted magnetic resonance (MR) imaging, Dynamic Contrast material–enhanced MR imaging, and quantitative three-dimensional (3D) proton MR spectroscopic imaging of the entire prostate for prostate cancer localization, with whole-mount histopathologic section findings as the reference standard. Materials and Methods: This study was approved by the institutional review board, and informed consent was obtained from all patients. Thirty-four consecutive men with a mean age of 60 years and a mean prostate-specific antigen level of 8 ng/mL were examined. The median biopsy Gleason score was 6. T2-weighted MR imaging, Dynamic Contrast-enhanced MR imaging, and 3D MR spectroscopic imaging were performed, and on the basis of the image data, two readers with different levels of experience recorded the location of the suspicious peripheral zone and central gland tumor nodules on each of 14 standardized regions of interest (ROIs) in the prostate. The degree of di...
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Prostate Cancer Localization with Dynamic Contrast-enhanced MR Imaging and Proton MR Spectroscopic Imaging
Radiology, 2006Co-Authors: Jurgen J Futterer, Stijn W. T. P. J. Heijmink, Tom W. J. Scheenen, Jeroen Veltman, Pieter Vos, Christina A. Hulsbergen–van De Kaa, Paul F. M. Krabbe, J. Alfred Witjes, Henkjan J Huisman, Arend HeerschapAbstract:Purpose: To prospectively determine the accuracies of T2-weighted magnetic resonance (MR) imaging, Dynamic Contrast material-enhanced MR imaging, and quantitative three-dimensional (3D) proton MR spectroscopic imaging of the entire prostate for prostate cancer localization, with whole-mount histopathologic section findings as the reference standard. Materials and Methods: This study was approved by the institutional review board, and informed consent was obtained from all patients. Thirty-four consecutive men with a mean age of 60 years and a mean prostate-specific antigen level of 8 ng/mL were examined. The median biopsy Gleason score was 6. T2-weighted MR imaging, Dynamic Contrast-enhanced MR imaging, and 3D MR spectroscopic imaging were performed, and on the basis of the image data, two readers with different levels of experience recorded the location of the suspicious peripheral zone and central gland tumor nodules on each of 14 standardized regions of interest (ROIs) in the prostate. The degree of diagnostic confidence for each ROI was recorded on a five-point scale. Localization accuracy and ROI-based receiver operating characteristic (ROC) curves were calculated. Results: For both readers, areas under the ROC curve for T2-weighted MR, Dynamic Contrast-enhanced MR, and 3D MR spectroscopic imaging were 0.68, 0.91, and 0.80, respectively. Reader accuracy in tumor localization with Dynamic Contrast-enhanced imaging was significantly better than that with quantitative spectroscopic imaging (P < .01). Reader accuracy in tumor localization with both Dynamic Contrast-enhanced imaging and spectroscopic imaging was significantly better than that with T2-weighted imaging (P < .01). Conclusion: Compared with use of T2-weighted MR imaging, use of Dynamic Contrast-enhanced MR imaging and 3D MR spectroscopic imaging facilitated significantly improved accuracy in prostate cancer localization. (C) RSNA, 2006
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staging prostate cancer with Dynamic Contrast enhanced endorectal mr imaging prior to radical prostatectomy experienced versus less experienced readers
Radiology, 2005Co-Authors: Jurgen J Futterer, Henkjan J Huisman, Alfred J Witjes, Marc R Engelbrecht, G J Jager, Jelle O BarentszAbstract:PURPOSE: To prospectively determine the accuracy of experienced and less experienced readers in the interpretation of combined T2-weighted fast spin-echo (SE) magnetic resonance (MR) images and Dynamic Contrast material–enhanced MR images compared with T2-weighted fast SE alone, with respect to differentiation of stage T2 versus stage T3 prostate carcinoma, with histologic analysis serving as the reference standard. MATERIALS AND METHODS: Institutional review board approval and informed consent were obtained, and 124 consecutive men (age range, 42–74 years; median age, 63 years) with biopsy-proved prostate cancer underwent MR imaging and were candidates for radical prostatectomy. T2-weighted fast SE MR images and multisection Dynamic Contrast-enhanced MR images with a 2-second time resolution for the whole prostate were obtained. The T2-weighted and fused color-coded parametric Dynamic Contrast-enhanced MR images with T2-weighted images were evaluated prospectively and scored with regard to local extent b...
Jelle O Barentsz - One of the best experts on this subject based on the ideXlab platform.
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prostate cancer localization with Dynamic Contrast enhanced mr imaging and proton mr spectroscopic imaging
Radiology, 2006Co-Authors: Jurgen J Futterer, Arend Heerschap, Stijn W. T. P. J. Heijmink, Tom W. J. Scheenen, Jeroen Veltman, Paul F. M. Krabbe, Henkjan J Huisman, Alfred J Witjes, Jelle O BarentszAbstract:Purpose: To prospectively determine the accuracies of T2-weighted magnetic resonance (MR) imaging, Dynamic Contrast material–enhanced MR imaging, and quantitative three-dimensional (3D) proton MR spectroscopic imaging of the entire prostate for prostate cancer localization, with whole-mount histopathologic section findings as the reference standard. Materials and Methods: This study was approved by the institutional review board, and informed consent was obtained from all patients. Thirty-four consecutive men with a mean age of 60 years and a mean prostate-specific antigen level of 8 ng/mL were examined. The median biopsy Gleason score was 6. T2-weighted MR imaging, Dynamic Contrast-enhanced MR imaging, and 3D MR spectroscopic imaging were performed, and on the basis of the image data, two readers with different levels of experience recorded the location of the suspicious peripheral zone and central gland tumor nodules on each of 14 standardized regions of interest (ROIs) in the prostate. The degree of di...
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staging prostate cancer with Dynamic Contrast enhanced endorectal mr imaging prior to radical prostatectomy experienced versus less experienced readers
Radiology, 2005Co-Authors: Jurgen J Futterer, Henkjan J Huisman, Alfred J Witjes, Marc R Engelbrecht, G J Jager, Jelle O BarentszAbstract:PURPOSE: To prospectively determine the accuracy of experienced and less experienced readers in the interpretation of combined T2-weighted fast spin-echo (SE) magnetic resonance (MR) images and Dynamic Contrast material–enhanced MR images compared with T2-weighted fast SE alone, with respect to differentiation of stage T2 versus stage T3 prostate carcinoma, with histologic analysis serving as the reference standard. MATERIALS AND METHODS: Institutional review board approval and informed consent were obtained, and 124 consecutive men (age range, 42–74 years; median age, 63 years) with biopsy-proved prostate cancer underwent MR imaging and were candidates for radical prostatectomy. T2-weighted fast SE MR images and multisection Dynamic Contrast-enhanced MR images with a 2-second time resolution for the whole prostate were obtained. The T2-weighted and fused color-coded parametric Dynamic Contrast-enhanced MR images with T2-weighted images were evaluated prospectively and scored with regard to local extent b...
Arend Heerschap - One of the best experts on this subject based on the ideXlab platform.
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prostate cancer localization with Dynamic Contrast enhanced mr imaging and proton mr spectroscopic imaging
Radiology, 2006Co-Authors: Jurgen J Futterer, Arend Heerschap, Stijn W. T. P. J. Heijmink, Tom W. J. Scheenen, Jeroen Veltman, Paul F. M. Krabbe, Henkjan J Huisman, Alfred J Witjes, Jelle O BarentszAbstract:Purpose: To prospectively determine the accuracies of T2-weighted magnetic resonance (MR) imaging, Dynamic Contrast material–enhanced MR imaging, and quantitative three-dimensional (3D) proton MR spectroscopic imaging of the entire prostate for prostate cancer localization, with whole-mount histopathologic section findings as the reference standard. Materials and Methods: This study was approved by the institutional review board, and informed consent was obtained from all patients. Thirty-four consecutive men with a mean age of 60 years and a mean prostate-specific antigen level of 8 ng/mL were examined. The median biopsy Gleason score was 6. T2-weighted MR imaging, Dynamic Contrast-enhanced MR imaging, and 3D MR spectroscopic imaging were performed, and on the basis of the image data, two readers with different levels of experience recorded the location of the suspicious peripheral zone and central gland tumor nodules on each of 14 standardized regions of interest (ROIs) in the prostate. The degree of di...
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Prostate Cancer Localization with Dynamic Contrast-enhanced MR Imaging and Proton MR Spectroscopic Imaging
Radiology, 2006Co-Authors: Jurgen J Futterer, Stijn W. T. P. J. Heijmink, Tom W. J. Scheenen, Jeroen Veltman, Pieter Vos, Christina A. Hulsbergen–van De Kaa, Paul F. M. Krabbe, J. Alfred Witjes, Henkjan J Huisman, Arend HeerschapAbstract:Purpose: To prospectively determine the accuracies of T2-weighted magnetic resonance (MR) imaging, Dynamic Contrast material-enhanced MR imaging, and quantitative three-dimensional (3D) proton MR spectroscopic imaging of the entire prostate for prostate cancer localization, with whole-mount histopathologic section findings as the reference standard. Materials and Methods: This study was approved by the institutional review board, and informed consent was obtained from all patients. Thirty-four consecutive men with a mean age of 60 years and a mean prostate-specific antigen level of 8 ng/mL were examined. The median biopsy Gleason score was 6. T2-weighted MR imaging, Dynamic Contrast-enhanced MR imaging, and 3D MR spectroscopic imaging were performed, and on the basis of the image data, two readers with different levels of experience recorded the location of the suspicious peripheral zone and central gland tumor nodules on each of 14 standardized regions of interest (ROIs) in the prostate. The degree of diagnostic confidence for each ROI was recorded on a five-point scale. Localization accuracy and ROI-based receiver operating characteristic (ROC) curves were calculated. Results: For both readers, areas under the ROC curve for T2-weighted MR, Dynamic Contrast-enhanced MR, and 3D MR spectroscopic imaging were 0.68, 0.91, and 0.80, respectively. Reader accuracy in tumor localization with Dynamic Contrast-enhanced imaging was significantly better than that with quantitative spectroscopic imaging (P < .01). Reader accuracy in tumor localization with both Dynamic Contrast-enhanced imaging and spectroscopic imaging was significantly better than that with T2-weighted imaging (P < .01). Conclusion: Compared with use of T2-weighted MR imaging, use of Dynamic Contrast-enhanced MR imaging and 3D MR spectroscopic imaging facilitated significantly improved accuracy in prostate cancer localization. (C) RSNA, 2006
Henkjan J Huisman - One of the best experts on this subject based on the ideXlab platform.
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prostate cancer localization with Dynamic Contrast enhanced mr imaging and proton mr spectroscopic imaging
Radiology, 2006Co-Authors: Jurgen J Futterer, Arend Heerschap, Stijn W. T. P. J. Heijmink, Tom W. J. Scheenen, Jeroen Veltman, Paul F. M. Krabbe, Henkjan J Huisman, Alfred J Witjes, Jelle O BarentszAbstract:Purpose: To prospectively determine the accuracies of T2-weighted magnetic resonance (MR) imaging, Dynamic Contrast material–enhanced MR imaging, and quantitative three-dimensional (3D) proton MR spectroscopic imaging of the entire prostate for prostate cancer localization, with whole-mount histopathologic section findings as the reference standard. Materials and Methods: This study was approved by the institutional review board, and informed consent was obtained from all patients. Thirty-four consecutive men with a mean age of 60 years and a mean prostate-specific antigen level of 8 ng/mL were examined. The median biopsy Gleason score was 6. T2-weighted MR imaging, Dynamic Contrast-enhanced MR imaging, and 3D MR spectroscopic imaging were performed, and on the basis of the image data, two readers with different levels of experience recorded the location of the suspicious peripheral zone and central gland tumor nodules on each of 14 standardized regions of interest (ROIs) in the prostate. The degree of di...
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Prostate Cancer Localization with Dynamic Contrast-enhanced MR Imaging and Proton MR Spectroscopic Imaging
Radiology, 2006Co-Authors: Jurgen J Futterer, Stijn W. T. P. J. Heijmink, Tom W. J. Scheenen, Jeroen Veltman, Pieter Vos, Christina A. Hulsbergen–van De Kaa, Paul F. M. Krabbe, J. Alfred Witjes, Henkjan J Huisman, Arend HeerschapAbstract:Purpose: To prospectively determine the accuracies of T2-weighted magnetic resonance (MR) imaging, Dynamic Contrast material-enhanced MR imaging, and quantitative three-dimensional (3D) proton MR spectroscopic imaging of the entire prostate for prostate cancer localization, with whole-mount histopathologic section findings as the reference standard. Materials and Methods: This study was approved by the institutional review board, and informed consent was obtained from all patients. Thirty-four consecutive men with a mean age of 60 years and a mean prostate-specific antigen level of 8 ng/mL were examined. The median biopsy Gleason score was 6. T2-weighted MR imaging, Dynamic Contrast-enhanced MR imaging, and 3D MR spectroscopic imaging were performed, and on the basis of the image data, two readers with different levels of experience recorded the location of the suspicious peripheral zone and central gland tumor nodules on each of 14 standardized regions of interest (ROIs) in the prostate. The degree of diagnostic confidence for each ROI was recorded on a five-point scale. Localization accuracy and ROI-based receiver operating characteristic (ROC) curves were calculated. Results: For both readers, areas under the ROC curve for T2-weighted MR, Dynamic Contrast-enhanced MR, and 3D MR spectroscopic imaging were 0.68, 0.91, and 0.80, respectively. Reader accuracy in tumor localization with Dynamic Contrast-enhanced imaging was significantly better than that with quantitative spectroscopic imaging (P < .01). Reader accuracy in tumor localization with both Dynamic Contrast-enhanced imaging and spectroscopic imaging was significantly better than that with T2-weighted imaging (P < .01). Conclusion: Compared with use of T2-weighted MR imaging, use of Dynamic Contrast-enhanced MR imaging and 3D MR spectroscopic imaging facilitated significantly improved accuracy in prostate cancer localization. (C) RSNA, 2006
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staging prostate cancer with Dynamic Contrast enhanced endorectal mr imaging prior to radical prostatectomy experienced versus less experienced readers
Radiology, 2005Co-Authors: Jurgen J Futterer, Henkjan J Huisman, Alfred J Witjes, Marc R Engelbrecht, G J Jager, Jelle O BarentszAbstract:PURPOSE: To prospectively determine the accuracy of experienced and less experienced readers in the interpretation of combined T2-weighted fast spin-echo (SE) magnetic resonance (MR) images and Dynamic Contrast material–enhanced MR images compared with T2-weighted fast SE alone, with respect to differentiation of stage T2 versus stage T3 prostate carcinoma, with histologic analysis serving as the reference standard. MATERIALS AND METHODS: Institutional review board approval and informed consent were obtained, and 124 consecutive men (age range, 42–74 years; median age, 63 years) with biopsy-proved prostate cancer underwent MR imaging and were candidates for radical prostatectomy. T2-weighted fast SE MR images and multisection Dynamic Contrast-enhanced MR images with a 2-second time resolution for the whole prostate were obtained. The T2-weighted and fused color-coded parametric Dynamic Contrast-enhanced MR images with T2-weighted images were evaluated prospectively and scored with regard to local extent b...
Tom W. J. Scheenen - One of the best experts on this subject based on the ideXlab platform.
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prostate cancer localization with Dynamic Contrast enhanced mr imaging and proton mr spectroscopic imaging
Radiology, 2006Co-Authors: Jurgen J Futterer, Arend Heerschap, Stijn W. T. P. J. Heijmink, Tom W. J. Scheenen, Jeroen Veltman, Paul F. M. Krabbe, Henkjan J Huisman, Alfred J Witjes, Jelle O BarentszAbstract:Purpose: To prospectively determine the accuracies of T2-weighted magnetic resonance (MR) imaging, Dynamic Contrast material–enhanced MR imaging, and quantitative three-dimensional (3D) proton MR spectroscopic imaging of the entire prostate for prostate cancer localization, with whole-mount histopathologic section findings as the reference standard. Materials and Methods: This study was approved by the institutional review board, and informed consent was obtained from all patients. Thirty-four consecutive men with a mean age of 60 years and a mean prostate-specific antigen level of 8 ng/mL were examined. The median biopsy Gleason score was 6. T2-weighted MR imaging, Dynamic Contrast-enhanced MR imaging, and 3D MR spectroscopic imaging were performed, and on the basis of the image data, two readers with different levels of experience recorded the location of the suspicious peripheral zone and central gland tumor nodules on each of 14 standardized regions of interest (ROIs) in the prostate. The degree of di...
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Prostate Cancer Localization with Dynamic Contrast-enhanced MR Imaging and Proton MR Spectroscopic Imaging
Radiology, 2006Co-Authors: Jurgen J Futterer, Stijn W. T. P. J. Heijmink, Tom W. J. Scheenen, Jeroen Veltman, Pieter Vos, Christina A. Hulsbergen–van De Kaa, Paul F. M. Krabbe, J. Alfred Witjes, Henkjan J Huisman, Arend HeerschapAbstract:Purpose: To prospectively determine the accuracies of T2-weighted magnetic resonance (MR) imaging, Dynamic Contrast material-enhanced MR imaging, and quantitative three-dimensional (3D) proton MR spectroscopic imaging of the entire prostate for prostate cancer localization, with whole-mount histopathologic section findings as the reference standard. Materials and Methods: This study was approved by the institutional review board, and informed consent was obtained from all patients. Thirty-four consecutive men with a mean age of 60 years and a mean prostate-specific antigen level of 8 ng/mL were examined. The median biopsy Gleason score was 6. T2-weighted MR imaging, Dynamic Contrast-enhanced MR imaging, and 3D MR spectroscopic imaging were performed, and on the basis of the image data, two readers with different levels of experience recorded the location of the suspicious peripheral zone and central gland tumor nodules on each of 14 standardized regions of interest (ROIs) in the prostate. The degree of diagnostic confidence for each ROI was recorded on a five-point scale. Localization accuracy and ROI-based receiver operating characteristic (ROC) curves were calculated. Results: For both readers, areas under the ROC curve for T2-weighted MR, Dynamic Contrast-enhanced MR, and 3D MR spectroscopic imaging were 0.68, 0.91, and 0.80, respectively. Reader accuracy in tumor localization with Dynamic Contrast-enhanced imaging was significantly better than that with quantitative spectroscopic imaging (P < .01). Reader accuracy in tumor localization with both Dynamic Contrast-enhanced imaging and spectroscopic imaging was significantly better than that with T2-weighted imaging (P < .01). Conclusion: Compared with use of T2-weighted MR imaging, use of Dynamic Contrast-enhanced MR imaging and 3D MR spectroscopic imaging facilitated significantly improved accuracy in prostate cancer localization. (C) RSNA, 2006
