The Experts below are selected from a list of 822 Experts worldwide ranked by ideXlab platform
Paeprer H - One of the best experts on this subject based on the ideXlab platform.
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Stress Echocardiography: evaluation of left ventricular function after administration of the transpulmonary Echo Contrast Medium SHU 508 A
Zeitschrift fur Kardiologie, 1993Co-Authors: Beckmann S, Schartl M, W. Bocksch, Paeprer HAbstract:Stress Echocardiography has recently gained increased importance as a method for assessment of left ventricular function. However, suboptimal image quality in some patients may limit use of this technique. In the present study, 10 patients with moderate image quality in the resting Echocardiograms (apical 4-chamberview) were reinvestigated after administration of the intravenous transpulmonary saccharide-based left heart Contrast agent SHU 508 A. Duration of Contrast enhancement in the left ventricle determined by visual assessment was 135 s (SEE +/- 39) at rest and 112 s (+/- 24) during maximum exercise. On a scale ranging from O (no Contrast) to 4 (excessively strong Contrast) enhancement averaged 2.5 at rest and during exercise. The left ventricle was divided into three segments (septum, apex, lateral wall) and delineation of the endocardial border was assessed. Detection of the border improved significantly after Contrast administration, especially at the lateral wall. Despite better visual assessment of the endocardial border, there was no improvement in automatic or semi-automatic contour recognition. No clinically significant side-effects were observed. Three patients reported a sensation of warmth at the injection site. In conclusion, intravenous administration of SHU 508 A improves visual detection of the left ventricular endocardial border in patients with suboptimal image quality and helps to achieve acceptable diagnostic accuracy with stress Echocardiography in these patients.
Hongjen Chiou - One of the best experts on this subject based on the ideXlab platform.
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soft tissue tumor differentiation using 3d power doppler ultrasonography with Echo Contrast Medium injection
Journal of The Chinese Medical Association, 2010Co-Authors: Hongjen Chiou, Yihong Chou, Weiming Chen, Winby Chen, Hsinkai Wang, Chengyen ChangAbstract:Background We aimed to evaluate the ability of 3-dimensional power Doppler ultrasonography to differentiate soft-tissue masses from blood flow and vascularization with Contrast Medium. Methods Twenty-five patients (mean age, 44.1 years; range, 12-77 years) with a palpable mass were enrolled in this study. Volume data were acquired using linear and convex 3-dimensional probes and Contrast Medium injected manually by bolus. Data were stored and traced slice by slice for 12 slices. All patients were scanned by the same senior sonologist. The vascular index (VI), flow index (FI), and vascular-flow index (VFI) were automatically calculated after the tumor was completely traced. All tumors were later confirmed by pathology. Results The study included 8 benign (mean, 36.5 mL; range, 2.4-124 mL) and 17 malignant (mean, 319.4 mL; range, 9.9-1,179.6 mL) tumors. Before Contrast Medium injection, mean VI, FI and VFI were, respectively, 3.22, 32.26 and 1.07 in benign tumors, and 1.97, 29.33 and 0.67 in malignant tumors. After Contrast Medium injection, they were, respectively, 20.85, 37.33 and 8.52 in benign tumors, and 40.12, 41.21 and 17.77 in malignant tumors. The mean differences between with and without Contrast injection for VI, FI and VFI were, respectively, 17.63, 5.07 and 7.45 in benign tumors, and 38.15, 11.88 and 16.55 in malignant tumors. Tumor volume, VI, FI and VFI were not significantly different between benign and malignant tumors before and after Echo-Contrast Medium injection. However, VI, FI and VFI under self-differentiation (differences between with and without Contrast injection) were significantly different between malignant and benign tumors. Conclusion Three-dimensional power Doppler ultrasound is a valuable tool for differential diagnosis of soft-tissue tumors, especially with the injection of an Echo-Contrast Medium.
H Schieffer - One of the best experts on this subject based on the ideXlab platform.
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femoral injection of Echo Contrast Medium may increase the sensitivity of testing for a patent foramen ovale
Neurology, 1998Co-Authors: Gerhard F Hamann, D Schatzerklotz, Gerd Frohlig, M Strittmatter, V Jost, G Berg, M Stopp, K Schimrigk, H SchiefferAbstract:Objective: The diagnosis of a patent foramen ovale (PFO) as a cause of stroke is of increasing interest especially in young ( Methods: We studied potential right-to-left shunting using transesophageal Echocardiography (TEE) and bilateral transcranial Doppler sonography (TCD) of the middle cerebral artery (MCA) simultaneously in 44 patients. All patients were younger than age 45 and suffered from an acute ischemic stroke or transient ischemic attack. Other possible etiologies were excluded. Echo Contrast Medium was injected in an alternating mode via antecubital or femoral veins. Tests were performed with and without the Valsalva maneuver. The criteria for a PFO were that the Contrast pass from the right to the left atrium (TEE) and early detection ( Results: A PFO was diagnosed in 22 patients (50%). The detection rate with TEE/TCD was 11.4%/4.5% via antecubital injection, 18%/13.6% via antecubital injection plus the Valsalva maneuver, 38.6%/36% via femoral injection alone, and 50%/50% via femoral injection plus the Valsalva maneuver. The difference between femoral and antecubital injections was significant with and without the Valsalva maneuver ( p 2 test). There were no differences between TEE and TCD after femoral injection with the Valsalva maneuver. The brain transit time was 4.6 ± 2.1 seconds for femoral injection and 6.3 ± 4.1 seconds for antecubital injection. Conclusions: The sensitivity in detecting a PFO was markedly increased by femoral injection. This may be caused by different inflow patterns to the right atrium: inferior vena caval flow is directed to the right atrial septum, whereas superior vena caval flow is directed to the tricuspid valve. Thus, femoral injection may help to improve the detection of PFO and may explain the differences between TEE and TCD findings in previous studies.
Beckmann S - One of the best experts on this subject based on the ideXlab platform.
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Stress Echocardiography: evaluation of left ventricular function after administration of the transpulmonary Echo Contrast Medium SHU 508 A
Zeitschrift fur Kardiologie, 1993Co-Authors: Beckmann S, Schartl M, W. Bocksch, Paeprer HAbstract:Stress Echocardiography has recently gained increased importance as a method for assessment of left ventricular function. However, suboptimal image quality in some patients may limit use of this technique. In the present study, 10 patients with moderate image quality in the resting Echocardiograms (apical 4-chamberview) were reinvestigated after administration of the intravenous transpulmonary saccharide-based left heart Contrast agent SHU 508 A. Duration of Contrast enhancement in the left ventricle determined by visual assessment was 135 s (SEE +/- 39) at rest and 112 s (+/- 24) during maximum exercise. On a scale ranging from O (no Contrast) to 4 (excessively strong Contrast) enhancement averaged 2.5 at rest and during exercise. The left ventricle was divided into three segments (septum, apex, lateral wall) and delineation of the endocardial border was assessed. Detection of the border improved significantly after Contrast administration, especially at the lateral wall. Despite better visual assessment of the endocardial border, there was no improvement in automatic or semi-automatic contour recognition. No clinically significant side-effects were observed. Three patients reported a sensation of warmth at the injection site. In conclusion, intravenous administration of SHU 508 A improves visual detection of the left ventricular endocardial border in patients with suboptimal image quality and helps to achieve acceptable diagnostic accuracy with stress Echocardiography in these patients.
Gotz Von Bernuth - One of the best experts on this subject based on the ideXlab platform.
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pericardial effusions in infants and children injection of Echo Contrast Medium enhances the safety of Echocardiographically guided pericardiocentesis
Cardiology in The Young, 1998Co-Authors: E G Muhler, W Engelhardt, Gotz Von BernuthAbstract:Pericardiocentesis is usually an easy and uncomplicated procedure when guided by cross-sectional Echocardiography, but an abnormal intracardiac or extrapericardial position of the puncture system can occur, especially in children. Injection of Echo Contrast Medium through the puncture needle is a very sensitive, quick, easy and harmless procedure which can be performed at the bedside in all cases in which doubt remains concerning the location of the needle. Prompt enhancement of signal intensity of the peri-cardial fluid validates the correct intrapericardial position, and permits visualization of the tip of the needle. Absence of Echodense formations excludes an intrapericardial position. We recommend the use of Echo Contrast Medium during pericardiocentesis whenever blood is aspirated through the needle, or if there is any doubt concerning its location.
