The Experts below are selected from a list of 234 Experts worldwide ranked by ideXlab platform

Emmanuel J Barbeau - One of the best experts on this subject based on the ideXlab platform.

  • Déjà-rêvé: Prior dreams induced by direct Electrical Brain Stimulation.
    Brain stimulation, 2018
    Co-Authors: Jonathan Curot, Jérémie Pariente, Marie Denuelle, Luc Valton, Fabrice Bartolomei, Agnès Trébuchon, Louis Maillard, Jean-pierre Vignal, Emmanuel J Barbeau
    Abstract:

    Abstract Background Epileptic patients sometimes report experiential phenomena related to a previous dream they had during seizures or Electrical Brain Stimulation (EBS). This has been alluded to in the literature as “deja-reve” (“already dreamed”). However, there is no neuroscientific evidence to support its existence and this concept is commonly mixed up with deja-vu. We hypothesized that deja-reve would be a specific entity, i.e., different from other experiential phenomena reported in epileptic patients, induced by EBS of specific Brain areas. Methods We collected all experiential phenomena related to dreams induced by Electrical Brain Stimulations (EBS) in our epileptic patients (2003–2015) and in a review of the literature. The content of these deja-reve and the location of EBS were analyzed. Results We collected 7 deja-reve in our database and 35 from the literature, which corresponds to an estimated prevalence of 0.3‰ of all EBS-inducing deja-reve. Deja-reve is a generic term for three distinct entities: it can be the recollection of a specific dream (“episodic-like”), reminiscence of a vague dream (“familiarity-like”) or experiences in which the subject feels like they are dreaming (literally “a dreamy state”). EBS-inducing “episodic-like” and “familiarity-like” deja-reve were mostly located in the medial temporal lobes. “Dreamy states” were induced by less specific EBS areas although still related to the temporal lobes. Conclusions This study demonstrates that deja-reve is a heterogeneous entity that is different from deja-vu, the historical “dreamy state” definition and other experiential phenomena. This may be relevant for clinical practice as it points to temporal lobe dysfunction and could be valuable for studying the neural substrates of dreams.

  • Déjà-rêvé: Prior dreams induced by direct Electrical Brain Stimulation
    Brain Stimulation, 2018
    Co-Authors: Jonathan Curot, Jérémie Pariente, Marie Denuelle, Luc Valton, Fabrice Bartolomei, Agnès Trébuchon, Louis Maillard, Jean-pierre Vignal, Emmanuel J Barbeau
    Abstract:

    Background: Epileptic patients sometimes report experiential phenomena related to a previous dream they had during seizures or Electrical Brain Stimulation (EBS). This has been alluded to in the literature as “déjà-rêvé” (“already dreamed”). However, there is no neuroscientific evidence to support its existence and this concept is commonly mixed up with déjà-vu. We hypothesized that déjà-rêvé would be a specific entity, i.e., different from other experiential phenomena reported in epileptic patients, induced by EBS of specific Brain areas. Methods: We collected all experiential phenomena related to dreams induced by Electrical Brain Stimulations (EBS) in our epileptic patients (2003–2015) and in a review of the literature. The content of these déjà-rêvé and the location of EBS were analyzed. Results: We collected 7 déjà-rêvé in our database and 35 from the literature, which corresponds to an estimated prevalence of 0.3‰ of all EBS-inducing déjà-rêvé. Déjà-rêvé is a generic term for three distinct entities: it can be the recollection of a specific dream (“episodic-like”), reminiscence of a vague dream (“familiarity-like”) or experiences in which the subject feels like they are dreaming (literally “a dreamy state”). EBS-inducing “episodic-like” and “familiarity-like” déjà-rêvé were mostly located in the medial temporal lobes. “Dreamy states” were induced by less specific EBS areas although still related to the temporal lobes. Conclusions: This study demonstrates that déjà-rêvé is a heterogeneous entity that is different from déjà-vu, the historical “dreamy state” definition and other experiential phenomena. This may be relevant for clinical practice as it points to temporal lobe dysfunction and could be valuable for studying the neural substrates of dreams.

Jonathan Curot - One of the best experts on this subject based on the ideXlab platform.

  • Déjà-rêvé: Prior dreams induced by direct Electrical Brain Stimulation.
    Brain stimulation, 2018
    Co-Authors: Jonathan Curot, Jérémie Pariente, Marie Denuelle, Luc Valton, Fabrice Bartolomei, Agnès Trébuchon, Louis Maillard, Jean-pierre Vignal, Emmanuel J Barbeau
    Abstract:

    Abstract Background Epileptic patients sometimes report experiential phenomena related to a previous dream they had during seizures or Electrical Brain Stimulation (EBS). This has been alluded to in the literature as “deja-reve” (“already dreamed”). However, there is no neuroscientific evidence to support its existence and this concept is commonly mixed up with deja-vu. We hypothesized that deja-reve would be a specific entity, i.e., different from other experiential phenomena reported in epileptic patients, induced by EBS of specific Brain areas. Methods We collected all experiential phenomena related to dreams induced by Electrical Brain Stimulations (EBS) in our epileptic patients (2003–2015) and in a review of the literature. The content of these deja-reve and the location of EBS were analyzed. Results We collected 7 deja-reve in our database and 35 from the literature, which corresponds to an estimated prevalence of 0.3‰ of all EBS-inducing deja-reve. Deja-reve is a generic term for three distinct entities: it can be the recollection of a specific dream (“episodic-like”), reminiscence of a vague dream (“familiarity-like”) or experiences in which the subject feels like they are dreaming (literally “a dreamy state”). EBS-inducing “episodic-like” and “familiarity-like” deja-reve were mostly located in the medial temporal lobes. “Dreamy states” were induced by less specific EBS areas although still related to the temporal lobes. Conclusions This study demonstrates that deja-reve is a heterogeneous entity that is different from deja-vu, the historical “dreamy state” definition and other experiential phenomena. This may be relevant for clinical practice as it points to temporal lobe dysfunction and could be valuable for studying the neural substrates of dreams.

  • Déjà-rêvé: Prior dreams induced by direct Electrical Brain Stimulation
    Brain Stimulation, 2018
    Co-Authors: Jonathan Curot, Jérémie Pariente, Marie Denuelle, Luc Valton, Fabrice Bartolomei, Agnès Trébuchon, Louis Maillard, Jean-pierre Vignal, Emmanuel J Barbeau
    Abstract:

    Background: Epileptic patients sometimes report experiential phenomena related to a previous dream they had during seizures or Electrical Brain Stimulation (EBS). This has been alluded to in the literature as “déjà-rêvé” (“already dreamed”). However, there is no neuroscientific evidence to support its existence and this concept is commonly mixed up with déjà-vu. We hypothesized that déjà-rêvé would be a specific entity, i.e., different from other experiential phenomena reported in epileptic patients, induced by EBS of specific Brain areas. Methods: We collected all experiential phenomena related to dreams induced by Electrical Brain Stimulations (EBS) in our epileptic patients (2003–2015) and in a review of the literature. The content of these déjà-rêvé and the location of EBS were analyzed. Results: We collected 7 déjà-rêvé in our database and 35 from the literature, which corresponds to an estimated prevalence of 0.3‰ of all EBS-inducing déjà-rêvé. Déjà-rêvé is a generic term for three distinct entities: it can be the recollection of a specific dream (“episodic-like”), reminiscence of a vague dream (“familiarity-like”) or experiences in which the subject feels like they are dreaming (literally “a dreamy state”). EBS-inducing “episodic-like” and “familiarity-like” déjà-rêvé were mostly located in the medial temporal lobes. “Dreamy states” were induced by less specific EBS areas although still related to the temporal lobes. Conclusions: This study demonstrates that déjà-rêvé is a heterogeneous entity that is different from déjà-vu, the historical “dreamy state” definition and other experiential phenomena. This may be relevant for clinical practice as it points to temporal lobe dysfunction and could be valuable for studying the neural substrates of dreams.

  • Memory scrutinized through Electrical Brain Stimulation: A review of 80 years of experiential phenomena
    Neuroscience & Biobehavioral Reviews, 2017
    Co-Authors: Jonathan Curot, Jérémie Pariente, Marie Denuelle, Luc Valton, Agnès Trébuchon, Louis Maillard, Jean-pierre Vignal, Thomas Busigny, Patrick Chauvel, Fabrice Bartolomei
    Abstract:

    Electrical Brain Stimulations (EBS) sometimes induce reminiscences, but it is largely unknown what type of memories they can trigger. We reviewed 80 years of literature on reminiscences induced by EBS and added our own database. We classified them according to modern conceptions of memory. We observed a surprisingly large variety of reminiscences covering all aspects of declarative memory. However, most were poorly detailed and only a few were episodic. This result does not support theories of a highly stable and detailed memory, as initially postulated, and still widely believed as true by the general public. Moreover, memory networks could only be activated by some of their nodes: 94.1% of EBS were temporal, although the parietal and frontal lobes, also involved in memory networks, were stimulated. The qualitative nature of memories largely depended on the site of Stimulation: EBS to rhinal cortex mostly induced personal semantic reminiscences, while only hippocampal EBS induced episodic memories. This result supports the view that EBS can activate memory in predictable ways in humans.

Fabrice Bartolomei - One of the best experts on this subject based on the ideXlab platform.

  • Déjà-rêvé: Prior dreams induced by direct Electrical Brain Stimulation.
    Brain stimulation, 2018
    Co-Authors: Jonathan Curot, Jérémie Pariente, Marie Denuelle, Luc Valton, Fabrice Bartolomei, Agnès Trébuchon, Louis Maillard, Jean-pierre Vignal, Emmanuel J Barbeau
    Abstract:

    Abstract Background Epileptic patients sometimes report experiential phenomena related to a previous dream they had during seizures or Electrical Brain Stimulation (EBS). This has been alluded to in the literature as “deja-reve” (“already dreamed”). However, there is no neuroscientific evidence to support its existence and this concept is commonly mixed up with deja-vu. We hypothesized that deja-reve would be a specific entity, i.e., different from other experiential phenomena reported in epileptic patients, induced by EBS of specific Brain areas. Methods We collected all experiential phenomena related to dreams induced by Electrical Brain Stimulations (EBS) in our epileptic patients (2003–2015) and in a review of the literature. The content of these deja-reve and the location of EBS were analyzed. Results We collected 7 deja-reve in our database and 35 from the literature, which corresponds to an estimated prevalence of 0.3‰ of all EBS-inducing deja-reve. Deja-reve is a generic term for three distinct entities: it can be the recollection of a specific dream (“episodic-like”), reminiscence of a vague dream (“familiarity-like”) or experiences in which the subject feels like they are dreaming (literally “a dreamy state”). EBS-inducing “episodic-like” and “familiarity-like” deja-reve were mostly located in the medial temporal lobes. “Dreamy states” were induced by less specific EBS areas although still related to the temporal lobes. Conclusions This study demonstrates that deja-reve is a heterogeneous entity that is different from deja-vu, the historical “dreamy state” definition and other experiential phenomena. This may be relevant for clinical practice as it points to temporal lobe dysfunction and could be valuable for studying the neural substrates of dreams.

  • Déjà-rêvé: Prior dreams induced by direct Electrical Brain Stimulation
    Brain Stimulation, 2018
    Co-Authors: Jonathan Curot, Jérémie Pariente, Marie Denuelle, Luc Valton, Fabrice Bartolomei, Agnès Trébuchon, Louis Maillard, Jean-pierre Vignal, Emmanuel J Barbeau
    Abstract:

    Background: Epileptic patients sometimes report experiential phenomena related to a previous dream they had during seizures or Electrical Brain Stimulation (EBS). This has been alluded to in the literature as “déjà-rêvé” (“already dreamed”). However, there is no neuroscientific evidence to support its existence and this concept is commonly mixed up with déjà-vu. We hypothesized that déjà-rêvé would be a specific entity, i.e., different from other experiential phenomena reported in epileptic patients, induced by EBS of specific Brain areas. Methods: We collected all experiential phenomena related to dreams induced by Electrical Brain Stimulations (EBS) in our epileptic patients (2003–2015) and in a review of the literature. The content of these déjà-rêvé and the location of EBS were analyzed. Results: We collected 7 déjà-rêvé in our database and 35 from the literature, which corresponds to an estimated prevalence of 0.3‰ of all EBS-inducing déjà-rêvé. Déjà-rêvé is a generic term for three distinct entities: it can be the recollection of a specific dream (“episodic-like”), reminiscence of a vague dream (“familiarity-like”) or experiences in which the subject feels like they are dreaming (literally “a dreamy state”). EBS-inducing “episodic-like” and “familiarity-like” déjà-rêvé were mostly located in the medial temporal lobes. “Dreamy states” were induced by less specific EBS areas although still related to the temporal lobes. Conclusions: This study demonstrates that déjà-rêvé is a heterogeneous entity that is different from déjà-vu, the historical “dreamy state” definition and other experiential phenomena. This may be relevant for clinical practice as it points to temporal lobe dysfunction and could be valuable for studying the neural substrates of dreams.

  • Memory scrutinized through Electrical Brain Stimulation: A review of 80 years of experiential phenomena
    Neuroscience & Biobehavioral Reviews, 2017
    Co-Authors: Jonathan Curot, Jérémie Pariente, Marie Denuelle, Luc Valton, Agnès Trébuchon, Louis Maillard, Jean-pierre Vignal, Thomas Busigny, Patrick Chauvel, Fabrice Bartolomei
    Abstract:

    Electrical Brain Stimulations (EBS) sometimes induce reminiscences, but it is largely unknown what type of memories they can trigger. We reviewed 80 years of literature on reminiscences induced by EBS and added our own database. We classified them according to modern conceptions of memory. We observed a surprisingly large variety of reminiscences covering all aspects of declarative memory. However, most were poorly detailed and only a few were episodic. This result does not support theories of a highly stable and detailed memory, as initially postulated, and still widely believed as true by the general public. Moreover, memory networks could only be activated by some of their nodes: 94.1% of EBS were temporal, although the parietal and frontal lobes, also involved in memory networks, were stimulated. The qualitative nature of memories largely depended on the site of Stimulation: EBS to rhinal cortex mostly induced personal semantic reminiscences, while only hippocampal EBS induced episodic memories. This result supports the view that EBS can activate memory in predictable ways in humans.

Stephen G. Holtzman - One of the best experts on this subject based on the ideXlab platform.

  • Do adenosinergic substrates mediate methylxanthine effects upon reinforcement thresholds for Electrical Brain Stimulation in the rat
    Brain Research, 1991
    Co-Authors: Geoffrey K. Mumford, Stephen G. Holtzman
    Abstract:

    Abstract Caffeine and other methylxanthines elevate reinforcement threshold for Electrical Brain Stimulation with an order of potency suggesting that the effect is mediated by antagonism of adenosine A2 receptors. The purpose of this study was to evaluate further the possible mechanism by which caffeine and other methylxanthines elevate reinforcement thresholds for ICSS. Drugs known to affect adenosinergic transmission in predictable ways, adenosine receptor agonists and antagonists and benzodiazepine agonists and inverse agonists, were tested to determine their effect upon reinforcement threshold. Both the selective A1 adenosine agonist, R(-)-PIA, and the non-selective A1/A2 adenosine agonist NECA failed to alter reinforcement thresholds, as did CGS 15943, a potent non-xanthine non-selective adenosine receptor antagonist. Chlordiazepoxide, a benzodiazepine agonist, lowered reinforcement thresholds and FG 7142, a benzodiazepine inverse agonist, elevated reinforcement thresholds, perhaps corresponding to their anxiolytic and anxiogenic subjective effects in humans. However, another benzodiazepine agonist, midazolam and another inverse agonist, β-CCE, did not alter reinforcement thresholds. These results fail to support a general role for adenosinergic systems in the threshold-elevating effect of methylxanthines.

  • Do adenosinergic substrates mediate methylxanthine effects upon reinforcement thresholds for Electrical Brain Stimulation in the rat
    Brain Research, 1991
    Co-Authors: Geoffrey K. Mumford, Stephen G. Holtzman
    Abstract:

    Abstract Caffeine and other methylxanthines elevate reinforcement threshold for Electrical Brain Stimulation with an order of potency suggesting that the effect is mediated by antagonism of adenosine A2 receptors. The purpose of this study was to evaluate further the possible mechanism by which caffeine and other methylxanthines elevate reinforcement thresholds for ICSS. Drugs known to affect adenosinergic transmission in predictable ways, adenosine receptor agonists and antagonists and benzodiazepine agonists and inverse agonists, were tested to determine their effect upon reinforcement threshold. Both the selective A1 adenosine agonist, R(-)-PIA, and the non-selective A1/A2 adenosine agonist NECA failed to alter reinforcement thresholds, as did CGS 15943, a potent non-xanthine non-selective adenosine receptor antagonist. Chlordiazepoxide, a benzodiazepine agonist, lowered reinforcement thresholds and FG 7142, a benzodiazepine inverse agonist, elevated reinforcement thresholds, perhaps corresponding to their anxiolytic and anxiogenic subjective effects in humans. However, another benzodiazepine agonist, midazolam and another inverse agonist, β-CCE, did not alter reinforcement thresholds. These results fail to support a general role for adenosinergic systems in the threshold-elevating effect of methylxanthines.

Luc Valton - One of the best experts on this subject based on the ideXlab platform.

  • Déjà-rêvé: Prior dreams induced by direct Electrical Brain Stimulation.
    Brain stimulation, 2018
    Co-Authors: Jonathan Curot, Jérémie Pariente, Marie Denuelle, Luc Valton, Fabrice Bartolomei, Agnès Trébuchon, Louis Maillard, Jean-pierre Vignal, Emmanuel J Barbeau
    Abstract:

    Abstract Background Epileptic patients sometimes report experiential phenomena related to a previous dream they had during seizures or Electrical Brain Stimulation (EBS). This has been alluded to in the literature as “deja-reve” (“already dreamed”). However, there is no neuroscientific evidence to support its existence and this concept is commonly mixed up with deja-vu. We hypothesized that deja-reve would be a specific entity, i.e., different from other experiential phenomena reported in epileptic patients, induced by EBS of specific Brain areas. Methods We collected all experiential phenomena related to dreams induced by Electrical Brain Stimulations (EBS) in our epileptic patients (2003–2015) and in a review of the literature. The content of these deja-reve and the location of EBS were analyzed. Results We collected 7 deja-reve in our database and 35 from the literature, which corresponds to an estimated prevalence of 0.3‰ of all EBS-inducing deja-reve. Deja-reve is a generic term for three distinct entities: it can be the recollection of a specific dream (“episodic-like”), reminiscence of a vague dream (“familiarity-like”) or experiences in which the subject feels like they are dreaming (literally “a dreamy state”). EBS-inducing “episodic-like” and “familiarity-like” deja-reve were mostly located in the medial temporal lobes. “Dreamy states” were induced by less specific EBS areas although still related to the temporal lobes. Conclusions This study demonstrates that deja-reve is a heterogeneous entity that is different from deja-vu, the historical “dreamy state” definition and other experiential phenomena. This may be relevant for clinical practice as it points to temporal lobe dysfunction and could be valuable for studying the neural substrates of dreams.

  • Déjà-rêvé: Prior dreams induced by direct Electrical Brain Stimulation
    Brain Stimulation, 2018
    Co-Authors: Jonathan Curot, Jérémie Pariente, Marie Denuelle, Luc Valton, Fabrice Bartolomei, Agnès Trébuchon, Louis Maillard, Jean-pierre Vignal, Emmanuel J Barbeau
    Abstract:

    Background: Epileptic patients sometimes report experiential phenomena related to a previous dream they had during seizures or Electrical Brain Stimulation (EBS). This has been alluded to in the literature as “déjà-rêvé” (“already dreamed”). However, there is no neuroscientific evidence to support its existence and this concept is commonly mixed up with déjà-vu. We hypothesized that déjà-rêvé would be a specific entity, i.e., different from other experiential phenomena reported in epileptic patients, induced by EBS of specific Brain areas. Methods: We collected all experiential phenomena related to dreams induced by Electrical Brain Stimulations (EBS) in our epileptic patients (2003–2015) and in a review of the literature. The content of these déjà-rêvé and the location of EBS were analyzed. Results: We collected 7 déjà-rêvé in our database and 35 from the literature, which corresponds to an estimated prevalence of 0.3‰ of all EBS-inducing déjà-rêvé. Déjà-rêvé is a generic term for three distinct entities: it can be the recollection of a specific dream (“episodic-like”), reminiscence of a vague dream (“familiarity-like”) or experiences in which the subject feels like they are dreaming (literally “a dreamy state”). EBS-inducing “episodic-like” and “familiarity-like” déjà-rêvé were mostly located in the medial temporal lobes. “Dreamy states” were induced by less specific EBS areas although still related to the temporal lobes. Conclusions: This study demonstrates that déjà-rêvé is a heterogeneous entity that is different from déjà-vu, the historical “dreamy state” definition and other experiential phenomena. This may be relevant for clinical practice as it points to temporal lobe dysfunction and could be valuable for studying the neural substrates of dreams.

  • Memory scrutinized through Electrical Brain Stimulation: A review of 80 years of experiential phenomena
    Neuroscience & Biobehavioral Reviews, 2017
    Co-Authors: Jonathan Curot, Jérémie Pariente, Marie Denuelle, Luc Valton, Agnès Trébuchon, Louis Maillard, Jean-pierre Vignal, Thomas Busigny, Patrick Chauvel, Fabrice Bartolomei
    Abstract:

    Electrical Brain Stimulations (EBS) sometimes induce reminiscences, but it is largely unknown what type of memories they can trigger. We reviewed 80 years of literature on reminiscences induced by EBS and added our own database. We classified them according to modern conceptions of memory. We observed a surprisingly large variety of reminiscences covering all aspects of declarative memory. However, most were poorly detailed and only a few were episodic. This result does not support theories of a highly stable and detailed memory, as initially postulated, and still widely believed as true by the general public. Moreover, memory networks could only be activated by some of their nodes: 94.1% of EBS were temporal, although the parietal and frontal lobes, also involved in memory networks, were stimulated. The qualitative nature of memories largely depended on the site of Stimulation: EBS to rhinal cortex mostly induced personal semantic reminiscences, while only hippocampal EBS induced episodic memories. This result supports the view that EBS can activate memory in predictable ways in humans.