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Камилов Феликс Хусаинович - One of the best experts on this subject based on the ideXlab platform.

  • Assessment of the body’s nonspecific defense in workers exposed to noxious factors of chemical and petrochemical industry
    Kazan medical journal, 2016
    Co-Authors: R. Sabitova, Сабитова Регина Игоревна, E D Kravets, Кравец Екатерина Дмитриевна, E.f. Galiullina, Галиуллина Эльвира Фанузовна, D F Shakirov, Шакиров Дамир Фаизович, F Kh Kamilov, Камилов Феликс Хусаинович
    Abstract:

    Aim. To study the processes of free-radical oxidation, antioxidant defense, energy Metabolism, Electrolyte Metabolism, and cytokine system reflecting the state of the non-specific defense of the body in workers exposed to complex of toxic substances under the conditions of manufacturing, substantiating the importance of indicators of preclinical diagnosis of disease development risk. Methods. The study included 90 workers of JSC «Experimental Plant Neftekhim», 95 workers of JSC «Kaustic» and 101 workers of JSC «Ufa plant of elastomeric materials, products and structures». Materials for the study were blood, mixed saliva, gingival fluid and urine. The laboratory studies were performed to evaluate the free radical oxidation processes, antioxidant defense, energy Metabolism, Electrolyte Metabolism, and cytokine system. Taking into account the features of industrial factors, particularly their effects on the workers bodies, routes of toxic compounds entry by inhalation, oral cavity and skin of the hands, three professional groups were formed (A, B, C). Group A included employees having constant contact with chlororganic compounds. The group B included persons who have constant contact with the higher and lower aromatic hydrocarbons. A group C consisted of employees who have constant contact with a mixture of chemicals: rubber compound containing carcinogens - benzo(a)pyrene, NDMA, nitrosodiethylamine; white carbon black, rubber dust, talc, amine compounds, sulfur dioxide, carbon monoxide. The control group consisted of employees of administrative and managerial staff. Results. The study revealed that one of the major pathogenetic mechanisms of action of chemical and petrochemical industry hazards is activation of free radical oxidation. Conclusion. Among the mechanisms of the influence of chemical contaminants of working environment a leading role play intensification of free radical oxidation processes, failure and/or inhibition of the antioxidant defense components.

R. Sabitova - One of the best experts on this subject based on the ideXlab platform.

  • Assessment of the body’s nonspecific defense in workers exposed to noxious factors of chemical and petrochemical industry
    Kazan medical journal, 2016
    Co-Authors: R. Sabitova, Сабитова Регина Игоревна, E D Kravets, Кравец Екатерина Дмитриевна, E.f. Galiullina, Галиуллина Эльвира Фанузовна, D F Shakirov, Шакиров Дамир Фаизович, F Kh Kamilov, Камилов Феликс Хусаинович
    Abstract:

    Aim. To study the processes of free-radical oxidation, antioxidant defense, energy Metabolism, Electrolyte Metabolism, and cytokine system reflecting the state of the non-specific defense of the body in workers exposed to complex of toxic substances under the conditions of manufacturing, substantiating the importance of indicators of preclinical diagnosis of disease development risk. Methods. The study included 90 workers of JSC «Experimental Plant Neftekhim», 95 workers of JSC «Kaustic» and 101 workers of JSC «Ufa plant of elastomeric materials, products and structures». Materials for the study were blood, mixed saliva, gingival fluid and urine. The laboratory studies were performed to evaluate the free radical oxidation processes, antioxidant defense, energy Metabolism, Electrolyte Metabolism, and cytokine system. Taking into account the features of industrial factors, particularly their effects on the workers bodies, routes of toxic compounds entry by inhalation, oral cavity and skin of the hands, three professional groups were formed (A, B, C). Group A included employees having constant contact with chlororganic compounds. The group B included persons who have constant contact with the higher and lower aromatic hydrocarbons. A group C consisted of employees who have constant contact with a mixture of chemicals: rubber compound containing carcinogens - benzo(a)pyrene, NDMA, nitrosodiethylamine; white carbon black, rubber dust, talc, amine compounds, sulfur dioxide, carbon monoxide. The control group consisted of employees of administrative and managerial staff. Results. The study revealed that one of the major pathogenetic mechanisms of action of chemical and petrochemical industry hazards is activation of free radical oxidation. Conclusion. Among the mechanisms of the influence of chemical contaminants of working environment a leading role play intensification of free radical oxidation processes, failure and/or inhibition of the antioxidant defense components.

  • assessment of the body s nonspecific defense in workers exposed to noxious factors of chemical and petrochemical industry
    Kazanskiy meditsinskiy zhurnal, 2016
    Co-Authors: R. Sabitova, E D Kravets, E.f. Galiullina, D F Shakirov, сабитова регина игоревна, кравец екатерина дмитриевна, галиуллина эльвира фанузовна, шакиров дамир фаизович, Kh F Kamilov, камилов феликс хусаинович
    Abstract:

    Aim. To study the processes of free-radical oxidation, antioxidant defense, energy Metabolism, Electrolyte Metabolism, and cytokine system reflecting the state of the non-specific defense of the body in workers exposed to complex of toxic substances under the conditions of manufacturing, substantiating the importance of indicators of preclinical diagnosis of disease development risk. Methods. The study included 90 workers of JSC «Experimental Plant Neftekhim», 95 workers of JSC «Kaustic» and 101 workers of JSC «Ufa plant of elastomeric materials, products and structures». Materials for the study were blood, mixed saliva, gingival fluid and urine. The laboratory studies were performed to evaluate the free radical oxidation processes, antioxidant defense, energy Metabolism, Electrolyte Metabolism, and cytokine system. Taking into account the features of industrial factors, particularly their effects on the workers bodies, routes of toxic compounds entry by inhalation, oral cavity and skin of the hands, three professional groups were formed (A, B, C). Group A included employees having constant contact with chlororganic compounds. The group B included persons who have constant contact with the higher and lower aromatic hydrocarbons. A group C consisted of employees who have constant contact with a mixture of chemicals: rubber compound containing carcinogens - benzo(a)pyrene, NDMA, nitrosodiethylamine; white carbon black, rubber dust, talc, amine compounds, sulfur dioxide, carbon monoxide. The control group consisted of employees of administrative and managerial staff. Results. The study revealed that one of the major pathogenetic mechanisms of action of chemical and petrochemical industry hazards is activation of free radical oxidation. Conclusion. Among the mechanisms of the influence of chemical contaminants of working environment a leading role play intensification of free radical oxidation processes, failure and/or inhibition of the antioxidant defense components.

D F Shakirov - One of the best experts on this subject based on the ideXlab platform.

  • Assessment of the body’s nonspecific defense in workers exposed to noxious factors of chemical and petrochemical industry
    Kazan medical journal, 2016
    Co-Authors: R. Sabitova, Сабитова Регина Игоревна, E D Kravets, Кравец Екатерина Дмитриевна, E.f. Galiullina, Галиуллина Эльвира Фанузовна, D F Shakirov, Шакиров Дамир Фаизович, F Kh Kamilov, Камилов Феликс Хусаинович
    Abstract:

    Aim. To study the processes of free-radical oxidation, antioxidant defense, energy Metabolism, Electrolyte Metabolism, and cytokine system reflecting the state of the non-specific defense of the body in workers exposed to complex of toxic substances under the conditions of manufacturing, substantiating the importance of indicators of preclinical diagnosis of disease development risk. Methods. The study included 90 workers of JSC «Experimental Plant Neftekhim», 95 workers of JSC «Kaustic» and 101 workers of JSC «Ufa plant of elastomeric materials, products and structures». Materials for the study were blood, mixed saliva, gingival fluid and urine. The laboratory studies were performed to evaluate the free radical oxidation processes, antioxidant defense, energy Metabolism, Electrolyte Metabolism, and cytokine system. Taking into account the features of industrial factors, particularly their effects on the workers bodies, routes of toxic compounds entry by inhalation, oral cavity and skin of the hands, three professional groups were formed (A, B, C). Group A included employees having constant contact with chlororganic compounds. The group B included persons who have constant contact with the higher and lower aromatic hydrocarbons. A group C consisted of employees who have constant contact with a mixture of chemicals: rubber compound containing carcinogens - benzo(a)pyrene, NDMA, nitrosodiethylamine; white carbon black, rubber dust, talc, amine compounds, sulfur dioxide, carbon monoxide. The control group consisted of employees of administrative and managerial staff. Results. The study revealed that one of the major pathogenetic mechanisms of action of chemical and petrochemical industry hazards is activation of free radical oxidation. Conclusion. Among the mechanisms of the influence of chemical contaminants of working environment a leading role play intensification of free radical oxidation processes, failure and/or inhibition of the antioxidant defense components.

  • assessment of the body s nonspecific defense in workers exposed to noxious factors of chemical and petrochemical industry
    Kazanskiy meditsinskiy zhurnal, 2016
    Co-Authors: R. Sabitova, E D Kravets, E.f. Galiullina, D F Shakirov, сабитова регина игоревна, кравец екатерина дмитриевна, галиуллина эльвира фанузовна, шакиров дамир фаизович, Kh F Kamilov, камилов феликс хусаинович
    Abstract:

    Aim. To study the processes of free-radical oxidation, antioxidant defense, energy Metabolism, Electrolyte Metabolism, and cytokine system reflecting the state of the non-specific defense of the body in workers exposed to complex of toxic substances under the conditions of manufacturing, substantiating the importance of indicators of preclinical diagnosis of disease development risk. Methods. The study included 90 workers of JSC «Experimental Plant Neftekhim», 95 workers of JSC «Kaustic» and 101 workers of JSC «Ufa plant of elastomeric materials, products and structures». Materials for the study were blood, mixed saliva, gingival fluid and urine. The laboratory studies were performed to evaluate the free radical oxidation processes, antioxidant defense, energy Metabolism, Electrolyte Metabolism, and cytokine system. Taking into account the features of industrial factors, particularly their effects on the workers bodies, routes of toxic compounds entry by inhalation, oral cavity and skin of the hands, three professional groups were formed (A, B, C). Group A included employees having constant contact with chlororganic compounds. The group B included persons who have constant contact with the higher and lower aromatic hydrocarbons. A group C consisted of employees who have constant contact with a mixture of chemicals: rubber compound containing carcinogens - benzo(a)pyrene, NDMA, nitrosodiethylamine; white carbon black, rubber dust, talc, amine compounds, sulfur dioxide, carbon monoxide. The control group consisted of employees of administrative and managerial staff. Results. The study revealed that one of the major pathogenetic mechanisms of action of chemical and petrochemical industry hazards is activation of free radical oxidation. Conclusion. Among the mechanisms of the influence of chemical contaminants of working environment a leading role play intensification of free radical oxidation processes, failure and/or inhibition of the antioxidant defense components.

  • Electrolyte Metabolism in workers engaged in oil refining industry
    Gigiena i sanitariia, 2001
    Co-Authors: D F Shakirov
    Abstract:

    The influence of unfavourable factors of the industrial environment on Electrolyte balance in the red blood cells and plasma of workers engaged in petroleum-refining industry was studied. All examinees were divided into 3 groups in terms of the exposure to chemical pollutants: 1) workers unexposed to chemical pollutants; 2) those exposed to them 2-3 times a week; 3) those exposed constantly during their work for 3-5 years. A control group included individuals who were not engaged in chemical industry. Groups 2 and 3 showed decreases in the levels of K, Mg, and Ca and increases in the concentrations of Na and P in the red blood cells and in those of K, Mg, and P in the plasma while plasma Na and Ca reduced.

Gyula Telegdy - One of the best experts on this subject based on the ideXlab platform.

  • central effects of antiserum against human atrial natriuretic polypeptide on water and Electrolyte Metabolism and plasma arginine 8 vasopressin level in conscious rats
    Neuropeptides, 1991
    Co-Authors: F Laczi, Gyula Szabo, I Jojart, Miklos Vecsernyes, S Csati, Gabor L Kovacs, F Szarvas, Gyula Telegdy
    Abstract:

    Although synthetic atrial natriuretic polypeptide (ANP) is known to influence the water and Electrolyte Metabolism and arginine-8-vasopressin (AVP) secretion, the physiological role of endogenous ANP in the rat brain is still unclear. Accordingly, an investigation was made of the effects of intracerebroventricular (icv) administration of human h-ANP antiserum, which can neutralize endogenous ANP, on the water intake, urine output, urinary excretion of potassium and sodium, and plasma AVP level in normally hydrated rats. Apart from the water intake, all the parameters were also determined in 48-h water-deprived rats after h-ANP antiserum treatment. The icv administration of the h-ANP antiserum significantly increased the spontaneous water intake, urine output and urinary potassium excretion in rats given water ad libitum. These effects developed by 24 h after icv treatment. The h-ANP antiserum had no effect on the urine volume in 48-h water-deprived rats, suggesting a primary effect of endogenous ANP in the brain on the spontaneous water intake in rats given water ad libitum. These results suggest that ANP may have a physiologically important role in the central regulation of the water and Electrolyte Metabolism. The h-ANP antiserum did not alter the basal and dehydration-induced AVP release. This raises the possibility that the endogenous ANP in the brain may not participate in the control of AVP secretion.

E.f. Galiullina - One of the best experts on this subject based on the ideXlab platform.

  • Assessment of the body’s nonspecific defense in workers exposed to noxious factors of chemical and petrochemical industry
    Kazan medical journal, 2016
    Co-Authors: R. Sabitova, Сабитова Регина Игоревна, E D Kravets, Кравец Екатерина Дмитриевна, E.f. Galiullina, Галиуллина Эльвира Фанузовна, D F Shakirov, Шакиров Дамир Фаизович, F Kh Kamilov, Камилов Феликс Хусаинович
    Abstract:

    Aim. To study the processes of free-radical oxidation, antioxidant defense, energy Metabolism, Electrolyte Metabolism, and cytokine system reflecting the state of the non-specific defense of the body in workers exposed to complex of toxic substances under the conditions of manufacturing, substantiating the importance of indicators of preclinical diagnosis of disease development risk. Methods. The study included 90 workers of JSC «Experimental Plant Neftekhim», 95 workers of JSC «Kaustic» and 101 workers of JSC «Ufa plant of elastomeric materials, products and structures». Materials for the study were blood, mixed saliva, gingival fluid and urine. The laboratory studies were performed to evaluate the free radical oxidation processes, antioxidant defense, energy Metabolism, Electrolyte Metabolism, and cytokine system. Taking into account the features of industrial factors, particularly their effects on the workers bodies, routes of toxic compounds entry by inhalation, oral cavity and skin of the hands, three professional groups were formed (A, B, C). Group A included employees having constant contact with chlororganic compounds. The group B included persons who have constant contact with the higher and lower aromatic hydrocarbons. A group C consisted of employees who have constant contact with a mixture of chemicals: rubber compound containing carcinogens - benzo(a)pyrene, NDMA, nitrosodiethylamine; white carbon black, rubber dust, talc, amine compounds, sulfur dioxide, carbon monoxide. The control group consisted of employees of administrative and managerial staff. Results. The study revealed that one of the major pathogenetic mechanisms of action of chemical and petrochemical industry hazards is activation of free radical oxidation. Conclusion. Among the mechanisms of the influence of chemical contaminants of working environment a leading role play intensification of free radical oxidation processes, failure and/or inhibition of the antioxidant defense components.

  • assessment of the body s nonspecific defense in workers exposed to noxious factors of chemical and petrochemical industry
    Kazanskiy meditsinskiy zhurnal, 2016
    Co-Authors: R. Sabitova, E D Kravets, E.f. Galiullina, D F Shakirov, сабитова регина игоревна, кравец екатерина дмитриевна, галиуллина эльвира фанузовна, шакиров дамир фаизович, Kh F Kamilov, камилов феликс хусаинович
    Abstract:

    Aim. To study the processes of free-radical oxidation, antioxidant defense, energy Metabolism, Electrolyte Metabolism, and cytokine system reflecting the state of the non-specific defense of the body in workers exposed to complex of toxic substances under the conditions of manufacturing, substantiating the importance of indicators of preclinical diagnosis of disease development risk. Methods. The study included 90 workers of JSC «Experimental Plant Neftekhim», 95 workers of JSC «Kaustic» and 101 workers of JSC «Ufa plant of elastomeric materials, products and structures». Materials for the study were blood, mixed saliva, gingival fluid and urine. The laboratory studies were performed to evaluate the free radical oxidation processes, antioxidant defense, energy Metabolism, Electrolyte Metabolism, and cytokine system. Taking into account the features of industrial factors, particularly their effects on the workers bodies, routes of toxic compounds entry by inhalation, oral cavity and skin of the hands, three professional groups were formed (A, B, C). Group A included employees having constant contact with chlororganic compounds. The group B included persons who have constant contact with the higher and lower aromatic hydrocarbons. A group C consisted of employees who have constant contact with a mixture of chemicals: rubber compound containing carcinogens - benzo(a)pyrene, NDMA, nitrosodiethylamine; white carbon black, rubber dust, talc, amine compounds, sulfur dioxide, carbon monoxide. The control group consisted of employees of administrative and managerial staff. Results. The study revealed that one of the major pathogenetic mechanisms of action of chemical and petrochemical industry hazards is activation of free radical oxidation. Conclusion. Among the mechanisms of the influence of chemical contaminants of working environment a leading role play intensification of free radical oxidation processes, failure and/or inhibition of the antioxidant defense components.