The Experts below are selected from a list of 8421 Experts worldwide ranked by ideXlab platform
Vitalij D Shteingarts - One of the best experts on this subject based on the ideXlab platform.
-
skraup like cyclization of polyfluoro 2 naphthylamines vicarious Electrophilic Substitution of fluorine
ChemInform, 2012Co-Authors: Galina A Selivanova, Alexey V Reshetov, Irina Yu Bagryanskaya, Vitalij D ShteingartsAbstract:This rare fluorine Substitution process putatively proceeds via the mechanism of vicarious Electrophilic Substitution.
-
Skraup‐Like Cyclization of Polyfluoro‐2‐naphthylamines: Vicarious Electrophilic Substitution of Fluorine.
ChemInform, 2012Co-Authors: Galina A Selivanova, Alexey V Reshetov, Irina Yu Bagryanskaya, Vitalij D ShteingartsAbstract:This rare fluorine Substitution process putatively proceeds via the mechanism of vicarious Electrophilic Substitution.
-
Skraup-like cyclization of polyfluoro-2-naphthylamines: Vicarious Electrophilic Substitution of fluorine
Journal of Fluorine Chemistry, 2012Co-Authors: Galina A Selivanova, Alexey V Reshetov, Irina Yu Bagryanskaya, Vitalij D ShteingartsAbstract:Abstract Treatment of polyfluoro-2-naphthylamines with glycerol in H 2 SO 4 or CF 3 SO 3 H at 150–160 °C gives respective polyfluorobenzo[f]quinolines. The reaction is suggested to proceed via intramolecular vicarious Electrophilic Substitution of fluorine at the α-position of polyfluorinated naphthalene core.
Luisa Pisano - One of the best experts on this subject based on the ideXlab platform.
-
Metalation of arylmethyl methyl ethers and connection with their reductive Electrophilic Substitution
Tetrahedron Letters, 1995Co-Authors: Ugo Azzena, Giovanni Melloni, Salvatore Demartis, Maria Giovanna Fiori, Luisa PisanoAbstract:Abstract Stable α-methoxy arylmethyl carbanions can be generated by metalation of arylmethyl methyl ethers, 1 , with n -BuLi in THF at −40 °C, avoiding Wittig rearrangement to the corresponding alkoxides 2 . Reaction of these carbanions with various electrophiles afforded the expected products 3 in satisfactory yields. Connection between the metalation procedure and the reductive Electrophilic Substitution of arylmethyl methyl ethers allowed the transformation of compounds 1 into 2-arylpropanoic acids, 5 .
-
Reductive Electrophilic Substitution of phthalans and ring expansion to isochroman derivatives
Tetrahedron Letters, 1995Co-Authors: Ugo Azzena, Giovanni Melloni, Salvatore Demartis, Maria Giovanna Fiori, Luisa PisanoAbstract:Reductive cleavage of phthalun, 1a, with Li metal in the presence of a catalytic amount of naphthalene leads to the formation of a stable aromatic dilithium compound. The adducts of the latter with CO2, aldehydes or ketones undergo ring closure to isochroman derivatives, leading to ring expansion of the original heterocycle. The reductive Electrophilic Substitution procedure was successfully extended to the substituted phthalans 1b and 1c, to afford the corresponding isochroman-3ones in satisfactory yields.
-
Reductive Electrophilic Substitution of pyrogallol derivatives : synthesis of 2,3-disubstituted phenols
Tetrahedron Letters, 1993Co-Authors: Ugo Azzena, Giovanni Melloni, Luisa PisanoAbstract:Abstract 1-2-Dimethoxy-3-methoxymethoxybenzene, 1 , was used as the starting material for the transformation of a 1,2,3-trioxybenzene into various 1-oxy-2,3-dicarbobenzenes, via regioselective reductive Electrophilic Substitution of the 2-methoxy group followed by Pd-catalyzed cross-coupling reaction.
Galina A Selivanova - One of the best experts on this subject based on the ideXlab platform.
-
skraup like cyclization of polyfluoro 2 naphthylamines vicarious Electrophilic Substitution of fluorine
ChemInform, 2012Co-Authors: Galina A Selivanova, Alexey V Reshetov, Irina Yu Bagryanskaya, Vitalij D ShteingartsAbstract:This rare fluorine Substitution process putatively proceeds via the mechanism of vicarious Electrophilic Substitution.
-
Skraup‐Like Cyclization of Polyfluoro‐2‐naphthylamines: Vicarious Electrophilic Substitution of Fluorine.
ChemInform, 2012Co-Authors: Galina A Selivanova, Alexey V Reshetov, Irina Yu Bagryanskaya, Vitalij D ShteingartsAbstract:This rare fluorine Substitution process putatively proceeds via the mechanism of vicarious Electrophilic Substitution.
-
Skraup-like cyclization of polyfluoro-2-naphthylamines: Vicarious Electrophilic Substitution of fluorine
Journal of Fluorine Chemistry, 2012Co-Authors: Galina A Selivanova, Alexey V Reshetov, Irina Yu Bagryanskaya, Vitalij D ShteingartsAbstract:Abstract Treatment of polyfluoro-2-naphthylamines with glycerol in H 2 SO 4 or CF 3 SO 3 H at 150–160 °C gives respective polyfluorobenzo[f]quinolines. The reaction is suggested to proceed via intramolecular vicarious Electrophilic Substitution of fluorine at the α-position of polyfluorinated naphthalene core.
Ugo Azzena - One of the best experts on this subject based on the ideXlab platform.
-
Metalation of arylmethyl methyl ethers and connection with their reductive Electrophilic Substitution
Tetrahedron Letters, 1995Co-Authors: Ugo Azzena, Giovanni Melloni, Salvatore Demartis, Maria Giovanna Fiori, Luisa PisanoAbstract:Abstract Stable α-methoxy arylmethyl carbanions can be generated by metalation of arylmethyl methyl ethers, 1 , with n -BuLi in THF at −40 °C, avoiding Wittig rearrangement to the corresponding alkoxides 2 . Reaction of these carbanions with various electrophiles afforded the expected products 3 in satisfactory yields. Connection between the metalation procedure and the reductive Electrophilic Substitution of arylmethyl methyl ethers allowed the transformation of compounds 1 into 2-arylpropanoic acids, 5 .
-
Reductive Electrophilic Substitution of phthalans and ring expansion to isochroman derivatives
Tetrahedron Letters, 1995Co-Authors: Ugo Azzena, Giovanni Melloni, Salvatore Demartis, Maria Giovanna Fiori, Luisa PisanoAbstract:Reductive cleavage of phthalun, 1a, with Li metal in the presence of a catalytic amount of naphthalene leads to the formation of a stable aromatic dilithium compound. The adducts of the latter with CO2, aldehydes or ketones undergo ring closure to isochroman derivatives, leading to ring expansion of the original heterocycle. The reductive Electrophilic Substitution procedure was successfully extended to the substituted phthalans 1b and 1c, to afford the corresponding isochroman-3ones in satisfactory yields.
-
Reductive Electrophilic Substitution of pyrogallol derivatives : synthesis of 2,3-disubstituted phenols
Tetrahedron Letters, 1993Co-Authors: Ugo Azzena, Giovanni Melloni, Luisa PisanoAbstract:Abstract 1-2-Dimethoxy-3-methoxymethoxybenzene, 1 , was used as the starting material for the transformation of a 1,2,3-trioxybenzene into various 1-oxy-2,3-dicarbobenzenes, via regioselective reductive Electrophilic Substitution of the 2-methoxy group followed by Pd-catalyzed cross-coupling reaction.
Weihong Du - One of the best experts on this subject based on the ideXlab platform.
-
Molecular Engineering of Benzo[b]pyrylium Salts by Indirect Electrophilic Substitution
European Journal of Organic Chemistry, 1998Co-Authors: Alan Roy Katritzky, Peter Dr. Czerney, Julian R. Levell, Weihong DuAbstract:Benzotriazole-mediated indirect Electrophilic Substitution in the position para to the oxygen atom of benzo[b]pyrylium salts has been used for the synthesis of long-chain and bifunctional benzo[b]pyrylium species. The methodology has potential for application in high technology and the pharmaceutical industries, for the molecular engineering of new functionalized derivatives.