Embolization

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Oliver Dudeck - One of the best experts on this subject based on the ideXlab platform.

  • Embolization of the Gastroduodenal Artery Before Selective Internal Radiotherapy: A Prospectively Randomized Trial Comparing Platinum-Fibered Microcoils with the Amplatzer Vascular Plug II
    CardioVascular and Interventional Radiology, 2009
    Co-Authors: Maciej Pech, Annett Kraetsch, Gero Wieners, Ulf Redlich, Gunnar Gaffke, Jens Ricke, Oliver Dudeck
    Abstract:

    The Amplatzer Vascular Plug II (AVP II) is a novel device for transcatheter vessel occlusion, for which only limited comparative data exist. Embolotherapy of the gastroduodenal artery (GDA) is essential before internal radiotherapy (SIRT) in order to prevent radiation-induced peptic ulcerations due to migration of yttrium-90 microspheres. The purpose of this study was to compare the vascular anatomical limitations, procedure time, effectiveness, and safety of Embolization of the GDA with coils versus the AVP II. Fifty patients stratified for SIRT were prospectively randomized for Embolization of the GDA with either coils or the AVP II. The angle between the aorta and the celiac trunk, diameter of the GDA, fluoroscopy time and total time for Embolization, number of Embolization devices, complications, and durability of vessel occlusion at follow-up angiography for SIRT were recorded. A t -test was used for statistical analysis. Embolizations with either coils or the AVP II were technically feasible in all but two patients scheduled for Embolization of the GDA with the AVP II. In both cases the plug could not be positioned due to the small celiac trunk outlet angles of 17° and 21°. The mean diameter of the GDA was 3.7 mm (range, 2.2–4.8 mm) for both groups. The procedures differed significantly in fluoroscopy time (7.8 min for coils vs. 2.6 min for the AVP II; P  

  • Embolization of the gastroduodenal artery before selective internal radiotherapy a prospectively randomized trial comparing platinum fibered microcoils with the amplatzer vascular plug ii
    CardioVascular and Interventional Radiology, 2009
    Co-Authors: Maciej Pech, Annett Kraetsch, Gero Wieners, Ulf Redlich, Gunnar Gaffke, Jens Ricke, Oliver Dudeck
    Abstract:

    The Amplatzer Vascular Plug II (AVP II) is a novel device for transcatheter vessel occlusion, for which only limited comparative data exist. Embolotherapy of the gastroduodenal artery (GDA) is essential before internal radiotherapy (SIRT) in order to prevent radiation-induced peptic ulcerations due to migration of yttrium-90 microspheres. The purpose of this study was to compare the vascular anatomical limitations, procedure time, effectiveness, and safety of Embolization of the GDA with coils versus the AVP II. Fifty patients stratified for SIRT were prospectively randomized for Embolization of the GDA with either coils or the AVP II. The angle between the aorta and the celiac trunk, diameter of the GDA, fluoroscopy time and total time for Embolization, number of Embolization devices, complications, and durability of vessel occlusion at follow-up angiography for SIRT were recorded. A t-test was used for statistical analysis. Embolizations with either coils or the AVP II were technically feasible in all but two patients scheduled for Embolization of the GDA with the AVP II. In both cases the plug could not be positioned due to the small celiac trunk outlet angles of 17° and 21°. The mean diameter of the GDA was 3.7 mm (range, 2.2–4.8 mm) for both groups. The procedures differed significantly in fluoroscopy time (7.8 min for coils vs. 2.6 min for the AVP II; P < 0.001) and Embolization time (23.1 min for coils vs. 8.8 min for the AVP II; P < 0.001). A mean of 6.0 ± 3.2 coils were used for GDA Embolization, while no more than one AVP II was needed for successful vessel occlusion (P < 0.001). One coil migration occurred during coil Embolization, whereas no procedural complication was encountered with the use of the AVP II. Vessel reperfusion was noted in only one patient, in whom coil Embolization was performed. In conclusion, Embolization of the GDA with the AVP II is safe, easy, rapid, and highly effective; only an extremely sharp-angled celiac trunk outlet represented an anatomical limitation for device deployment.

Maciej Pech - One of the best experts on this subject based on the ideXlab platform.

  • Embolization of the Gastroduodenal Artery Before Selective Internal Radiotherapy: A Prospectively Randomized Trial Comparing Platinum-Fibered Microcoils with the Amplatzer Vascular Plug II
    CardioVascular and Interventional Radiology, 2009
    Co-Authors: Maciej Pech, Annett Kraetsch, Gero Wieners, Ulf Redlich, Gunnar Gaffke, Jens Ricke, Oliver Dudeck
    Abstract:

    The Amplatzer Vascular Plug II (AVP II) is a novel device for transcatheter vessel occlusion, for which only limited comparative data exist. Embolotherapy of the gastroduodenal artery (GDA) is essential before internal radiotherapy (SIRT) in order to prevent radiation-induced peptic ulcerations due to migration of yttrium-90 microspheres. The purpose of this study was to compare the vascular anatomical limitations, procedure time, effectiveness, and safety of Embolization of the GDA with coils versus the AVP II. Fifty patients stratified for SIRT were prospectively randomized for Embolization of the GDA with either coils or the AVP II. The angle between the aorta and the celiac trunk, diameter of the GDA, fluoroscopy time and total time for Embolization, number of Embolization devices, complications, and durability of vessel occlusion at follow-up angiography for SIRT were recorded. A t -test was used for statistical analysis. Embolizations with either coils or the AVP II were technically feasible in all but two patients scheduled for Embolization of the GDA with the AVP II. In both cases the plug could not be positioned due to the small celiac trunk outlet angles of 17° and 21°. The mean diameter of the GDA was 3.7 mm (range, 2.2–4.8 mm) for both groups. The procedures differed significantly in fluoroscopy time (7.8 min for coils vs. 2.6 min for the AVP II; P  

  • Embolization of the gastroduodenal artery before selective internal radiotherapy a prospectively randomized trial comparing platinum fibered microcoils with the amplatzer vascular plug ii
    CardioVascular and Interventional Radiology, 2009
    Co-Authors: Maciej Pech, Annett Kraetsch, Gero Wieners, Ulf Redlich, Gunnar Gaffke, Jens Ricke, Oliver Dudeck
    Abstract:

    The Amplatzer Vascular Plug II (AVP II) is a novel device for transcatheter vessel occlusion, for which only limited comparative data exist. Embolotherapy of the gastroduodenal artery (GDA) is essential before internal radiotherapy (SIRT) in order to prevent radiation-induced peptic ulcerations due to migration of yttrium-90 microspheres. The purpose of this study was to compare the vascular anatomical limitations, procedure time, effectiveness, and safety of Embolization of the GDA with coils versus the AVP II. Fifty patients stratified for SIRT were prospectively randomized for Embolization of the GDA with either coils or the AVP II. The angle between the aorta and the celiac trunk, diameter of the GDA, fluoroscopy time and total time for Embolization, number of Embolization devices, complications, and durability of vessel occlusion at follow-up angiography for SIRT were recorded. A t-test was used for statistical analysis. Embolizations with either coils or the AVP II were technically feasible in all but two patients scheduled for Embolization of the GDA with the AVP II. In both cases the plug could not be positioned due to the small celiac trunk outlet angles of 17° and 21°. The mean diameter of the GDA was 3.7 mm (range, 2.2–4.8 mm) for both groups. The procedures differed significantly in fluoroscopy time (7.8 min for coils vs. 2.6 min for the AVP II; P < 0.001) and Embolization time (23.1 min for coils vs. 8.8 min for the AVP II; P < 0.001). A mean of 6.0 ± 3.2 coils were used for GDA Embolization, while no more than one AVP II was needed for successful vessel occlusion (P < 0.001). One coil migration occurred during coil Embolization, whereas no procedural complication was encountered with the use of the AVP II. Vessel reperfusion was noted in only one patient, in whom coil Embolization was performed. In conclusion, Embolization of the GDA with the AVP II is safe, easy, rapid, and highly effective; only an extremely sharp-angled celiac trunk outlet represented an anatomical limitation for device deployment.

Daniel G Clair - One of the best experts on this subject based on the ideXlab platform.

  • long term follow up of type ii endoleak Embolization reveals the need for close surveillance
    Journal of Vascular Surgery, 2012
    Co-Authors: Timur P Sarac, Connor Gibbons, Lina Vargas, Sunita D Srivastava, James Bena, Tara M Mastracci, Vikram S Kashyap, Daniel G Clair
    Abstract:

    OBJECTIVE: Aneurysm growth after endovascular aneurysm repair (EVAR) in patients with type II endoleak is associated with adverse outcomes. This study evaluated the long-term success of Embolization of type II endoleaks in preventing aneurysm sac growth. METHODS: We retrospectively reviewed outcomes of patients who underwent infrarenal EVAR who were treated for a type II endoleak between 2000 and 2008. Computed tomography scans were evaluated for aneurysm sac growth or shrinkage from the time of treatment of the endoleak. The Embolization material used, graft type, target vessel embolized, and comorbidities were evaluated for their association with sac growth or shrinkage. RESULTS: Ninety-five patients underwent 140 Embolization procedures. The mean time from EVAR to Embolization was 26.1 ± 22.2 months, and the average increase in size of the aneurysm sac from EVAR to treatment was 0.7 × 0.5 cm. Patients underwent an average of 1.6 ± 0.8 Embolization procedures after EVAR. Thirteen patients underwent initial simultaneous Embolization of two targets. Embolization was with glue (61%), coils (29%), glue and coils (7%), and Gelfoam (3%; Pfizer Inc, New York, NY). No abdominal aortic aneurysms (AAA) ruptured. Eight patients (8.4%) underwent graft explant and open repair; 19 (20%) required two or more Embolization procedures. There was no difference in the target vessel treated or the treatment used in halting sac expansion (>5 mm). Coil Embolization alone resulted in more second procedures. The 5-year cumulative survival was 65% (95% confidence interval [CI], 52%-77%), freedom from explant was 89% (95% CI, 81%-97%), freedom from second Embolization was 76% (95% CI, 66%-86%), and freedom from sac expansion >5 mm was 44% (95% CI 30%-50%). Univariable analysis identified continued tobacco use (hazard ratio [HR], 2.30; 95% CI, 1.02-5.13; P = .04) was associated with continued sac expansion, and hyperlipidemia (HR, 9.64; 95% CI, 2.22-41.86) was associated with patients requiring a second Embolization procedure. CONCLUSIONS: Embolization of type II endoleaks is successful early in preventing aneurysm sac growth and rupture after EVAR. However, a significant number of patients require more than one procedure, and at 5 years, many patients who underwent Embolization of a type II endoleak continued to experience sac growth. Patients with hyperlipidemia who undergo coil Embolization are more likely to require a second Embolization procedure, and patients who smoke have a higher likelihood of AAA sac expansion after Embolization. Continued long-term surveillance is necessary in this cohort of patients.

Annett Kraetsch - One of the best experts on this subject based on the ideXlab platform.

  • Embolization of the Gastroduodenal Artery Before Selective Internal Radiotherapy: A Prospectively Randomized Trial Comparing Platinum-Fibered Microcoils with the Amplatzer Vascular Plug II
    CardioVascular and Interventional Radiology, 2009
    Co-Authors: Maciej Pech, Annett Kraetsch, Gero Wieners, Ulf Redlich, Gunnar Gaffke, Jens Ricke, Oliver Dudeck
    Abstract:

    The Amplatzer Vascular Plug II (AVP II) is a novel device for transcatheter vessel occlusion, for which only limited comparative data exist. Embolotherapy of the gastroduodenal artery (GDA) is essential before internal radiotherapy (SIRT) in order to prevent radiation-induced peptic ulcerations due to migration of yttrium-90 microspheres. The purpose of this study was to compare the vascular anatomical limitations, procedure time, effectiveness, and safety of Embolization of the GDA with coils versus the AVP II. Fifty patients stratified for SIRT were prospectively randomized for Embolization of the GDA with either coils or the AVP II. The angle between the aorta and the celiac trunk, diameter of the GDA, fluoroscopy time and total time for Embolization, number of Embolization devices, complications, and durability of vessel occlusion at follow-up angiography for SIRT were recorded. A t -test was used for statistical analysis. Embolizations with either coils or the AVP II were technically feasible in all but two patients scheduled for Embolization of the GDA with the AVP II. In both cases the plug could not be positioned due to the small celiac trunk outlet angles of 17° and 21°. The mean diameter of the GDA was 3.7 mm (range, 2.2–4.8 mm) for both groups. The procedures differed significantly in fluoroscopy time (7.8 min for coils vs. 2.6 min for the AVP II; P  

  • Embolization of the gastroduodenal artery before selective internal radiotherapy a prospectively randomized trial comparing platinum fibered microcoils with the amplatzer vascular plug ii
    CardioVascular and Interventional Radiology, 2009
    Co-Authors: Maciej Pech, Annett Kraetsch, Gero Wieners, Ulf Redlich, Gunnar Gaffke, Jens Ricke, Oliver Dudeck
    Abstract:

    The Amplatzer Vascular Plug II (AVP II) is a novel device for transcatheter vessel occlusion, for which only limited comparative data exist. Embolotherapy of the gastroduodenal artery (GDA) is essential before internal radiotherapy (SIRT) in order to prevent radiation-induced peptic ulcerations due to migration of yttrium-90 microspheres. The purpose of this study was to compare the vascular anatomical limitations, procedure time, effectiveness, and safety of Embolization of the GDA with coils versus the AVP II. Fifty patients stratified for SIRT were prospectively randomized for Embolization of the GDA with either coils or the AVP II. The angle between the aorta and the celiac trunk, diameter of the GDA, fluoroscopy time and total time for Embolization, number of Embolization devices, complications, and durability of vessel occlusion at follow-up angiography for SIRT were recorded. A t-test was used for statistical analysis. Embolizations with either coils or the AVP II were technically feasible in all but two patients scheduled for Embolization of the GDA with the AVP II. In both cases the plug could not be positioned due to the small celiac trunk outlet angles of 17° and 21°. The mean diameter of the GDA was 3.7 mm (range, 2.2–4.8 mm) for both groups. The procedures differed significantly in fluoroscopy time (7.8 min for coils vs. 2.6 min for the AVP II; P < 0.001) and Embolization time (23.1 min for coils vs. 8.8 min for the AVP II; P < 0.001). A mean of 6.0 ± 3.2 coils were used for GDA Embolization, while no more than one AVP II was needed for successful vessel occlusion (P < 0.001). One coil migration occurred during coil Embolization, whereas no procedural complication was encountered with the use of the AVP II. Vessel reperfusion was noted in only one patient, in whom coil Embolization was performed. In conclusion, Embolization of the GDA with the AVP II is safe, easy, rapid, and highly effective; only an extremely sharp-angled celiac trunk outlet represented an anatomical limitation for device deployment.

Jens Ricke - One of the best experts on this subject based on the ideXlab platform.

  • Embolization of the Gastroduodenal Artery Before Selective Internal Radiotherapy: A Prospectively Randomized Trial Comparing Platinum-Fibered Microcoils with the Amplatzer Vascular Plug II
    CardioVascular and Interventional Radiology, 2009
    Co-Authors: Maciej Pech, Annett Kraetsch, Gero Wieners, Ulf Redlich, Gunnar Gaffke, Jens Ricke, Oliver Dudeck
    Abstract:

    The Amplatzer Vascular Plug II (AVP II) is a novel device for transcatheter vessel occlusion, for which only limited comparative data exist. Embolotherapy of the gastroduodenal artery (GDA) is essential before internal radiotherapy (SIRT) in order to prevent radiation-induced peptic ulcerations due to migration of yttrium-90 microspheres. The purpose of this study was to compare the vascular anatomical limitations, procedure time, effectiveness, and safety of Embolization of the GDA with coils versus the AVP II. Fifty patients stratified for SIRT were prospectively randomized for Embolization of the GDA with either coils or the AVP II. The angle between the aorta and the celiac trunk, diameter of the GDA, fluoroscopy time and total time for Embolization, number of Embolization devices, complications, and durability of vessel occlusion at follow-up angiography for SIRT were recorded. A t -test was used for statistical analysis. Embolizations with either coils or the AVP II were technically feasible in all but two patients scheduled for Embolization of the GDA with the AVP II. In both cases the plug could not be positioned due to the small celiac trunk outlet angles of 17° and 21°. The mean diameter of the GDA was 3.7 mm (range, 2.2–4.8 mm) for both groups. The procedures differed significantly in fluoroscopy time (7.8 min for coils vs. 2.6 min for the AVP II; P  

  • Embolization of the gastroduodenal artery before selective internal radiotherapy a prospectively randomized trial comparing platinum fibered microcoils with the amplatzer vascular plug ii
    CardioVascular and Interventional Radiology, 2009
    Co-Authors: Maciej Pech, Annett Kraetsch, Gero Wieners, Ulf Redlich, Gunnar Gaffke, Jens Ricke, Oliver Dudeck
    Abstract:

    The Amplatzer Vascular Plug II (AVP II) is a novel device for transcatheter vessel occlusion, for which only limited comparative data exist. Embolotherapy of the gastroduodenal artery (GDA) is essential before internal radiotherapy (SIRT) in order to prevent radiation-induced peptic ulcerations due to migration of yttrium-90 microspheres. The purpose of this study was to compare the vascular anatomical limitations, procedure time, effectiveness, and safety of Embolization of the GDA with coils versus the AVP II. Fifty patients stratified for SIRT were prospectively randomized for Embolization of the GDA with either coils or the AVP II. The angle between the aorta and the celiac trunk, diameter of the GDA, fluoroscopy time and total time for Embolization, number of Embolization devices, complications, and durability of vessel occlusion at follow-up angiography for SIRT were recorded. A t-test was used for statistical analysis. Embolizations with either coils or the AVP II were technically feasible in all but two patients scheduled for Embolization of the GDA with the AVP II. In both cases the plug could not be positioned due to the small celiac trunk outlet angles of 17° and 21°. The mean diameter of the GDA was 3.7 mm (range, 2.2–4.8 mm) for both groups. The procedures differed significantly in fluoroscopy time (7.8 min for coils vs. 2.6 min for the AVP II; P < 0.001) and Embolization time (23.1 min for coils vs. 8.8 min for the AVP II; P < 0.001). A mean of 6.0 ± 3.2 coils were used for GDA Embolization, while no more than one AVP II was needed for successful vessel occlusion (P < 0.001). One coil migration occurred during coil Embolization, whereas no procedural complication was encountered with the use of the AVP II. Vessel reperfusion was noted in only one patient, in whom coil Embolization was performed. In conclusion, Embolization of the GDA with the AVP II is safe, easy, rapid, and highly effective; only an extremely sharp-angled celiac trunk outlet represented an anatomical limitation for device deployment.