The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Scott F. Gilbert - One of the best experts on this subject based on the ideXlab platform.
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The Morphogenesis Of Evolutionary Developmental Biology
The International Journal of Developmental Biology, 2003Co-Authors: Scott F. GilbertAbstract:The early studies of evolutionary developmental biology (Evo-Devo) come from several sources. Tributaries flowing into Evo-Devo came from such disciplines as Embryology, developmental genetics, evolutionary biology, ecology, paleontology, systematics, medical Embryology and mathematical modeling. This essay will trace one of the major pathways, that from evolutionary Embryology to Evo-Devo and it will show the interactions of this pathway with two other sources of Evo-Devo: ecological developmental biology and medical developmental biology. Together, these three fields are forming a more inclusive evolutionary developmental biology that is revitalizing and providing answers to old and important questions involving the formation of biodiversity on Earth. The phenotype of Evo-Devo is limited by internal constraints on what could be known given the methods and equipment of the time and it has been framed by external factors that include both academic and global politics.
Shane R Tubbs - One of the best experts on this subject based on the ideXlab platform.
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triangular shaped odontoid process with chiari 1 malformation patient
Cureus, 2020Co-Authors: Katherine Cironi, Joe Iwanaga, Aaron S. Dumont, Shane R TubbsAbstract:Several anatomical variations of osseous structures around the craniovertebral junction (CVJ) have been observed in those presenting with Chiari 1 malformation (CM-1) due to the junction's unique Embryology and its pivotal role in neck stability. During a clinic visit, a 14-year-old female presented with the classic symptoms of CM-1. Upon follow-up imaging and confirmation of the inferiorly displaced cerebellar tonsils, a unique triangular-shaped odontoid process was identified. To our knowledge, this osseous malformation of the dens has not been reported in the current literature. This unique deviation may cause ligamentous instability and decreased motion capacity and predispose a patient to axial fractures. Thus, we aim to further discuss this case, cervical vertebrae axis (C2) Embryology, and the resulting clinical significance of this observed odontoid process variant.
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Embryology of the craniocervical junction and posterior cranial fossa part i development of the upper vertebrae and skull
Clinical Anatomy, 2018Co-Authors: Mohammadali Mohajel Shoja, Rebecca C Ramdhan, Chad J Jensen, Joshua J Chern, Jerry W Oakes, Shane R TubbsAbstract:Although the Embryology of the posterior cranial fossa can have life altering effects on a patient, a comprehensive review on this topic is difficult to find in the peer-reviewed medical literature. Therefore, this review article, using standard search engines, seemed timely. The Embryology of the posterior cranial fossa is complex and relies on a unique timing of various neurovascular and bony elements. Derailment of these developmental processes can lead to a wide range of malformations such as the Chiari malformations. Therefore, a good working knowledge of this Embryology as outlined in this review of its bony architecture is important for those treating patients with involvement of this region of the cranium. Clin. Anat. 31:466-487, 2018. © 2018 Wiley Periodicals, Inc.
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Embryology of the craniocervical junction and posterior cranial fossa part ii embryogenesis of the hindbrain
Clinical Anatomy, 2018Co-Authors: Mohammadali Mohajel Shoja, Rebecca C Ramdhan, Chad J Jensen, Joshua J Chern, Jerry W Oakes, Shane R TubbsAbstract:Although pathology of the hindbrain and its derivatives can have life altering effects on a patient, a comprehensive review on its Embryology is difficult to find in the peer-reviewed medical literature. Therefore, this review article, using standard search engines, seemed timely. The Embryology of the hindbrain is complex and relies on a unique timing of various neurovascular and bony elements. Derailment of these developmental processes can lead to a wide range of malformations such as the Chiari malformations. Therefore, a good working knowledge of this Embryology as outlined in this review of the hindbrain is important for those treating patients with involvement of this region of the central nervous system. Clin. Anat. 31:488-500, 2018. © 2018 Wiley Periodicals, Inc.
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the cranial dura mater a review of its history Embryology and anatomy
Childs Nervous System, 2012Co-Authors: Nimer Adeeb, Shane R Tubbs, Martin M Mortazavi, Aaron A CohengadolAbstract:The dura mater is important to the clinician as a barrier to the internal environment of the brain, and surgically, its anatomy should be well known to the neurosurgeon and clinician who interpret imaging. The medical literature was reviewed in regard to the morphology and Embryology of specifically, the intracranial dura mater. A historic review of this meningeal layer is also provided. Knowledge of the cranial dura mater has a rich history. The Embryology is complex, and the surgical anatomy of this layer and its specializations are important to the neurosurgeon.
Norbert Gleicher - One of the best experts on this subject based on the ideXlab platform.
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different effectiveness of closed embryo culture system with time lapse imaging embryoscope tm in comparison to standard manual Embryology in good and poor prognosis patients a prospectively randomized pilot study
Reproductive Biology and Endocrinology, 2016Co-Authors: Yanguang Wu, E Lazzaronitealdi, David F Albertini, Sarah K Darmon, David H. Barad, Vitaly A Kushnir, Qi Wang, Lin Zhang, Norbert GleicherAbstract:Previously manual human Embryology in many in vitro fertilization (IVF) centers is rapidly being replaced by closed embryo incubation systems with time-lapse imaging. Whether such systems perform comparably to manual Embryology in different IVF patient populations has, however, never before been investigated. We, therefore, prospectively compared embryo quality following closed system culture with time-lapse photography (EmbryoScope™) and standard Embryology. We performed a two-part prospectively randomized study in IVF (clinical trial # NCT92256309). Part A involved 31 infertile poor prognosis patients prospectively randomized to EmbryoScope™ and standard Embryology. Part B involved embryos from 17 egg donor-recipient cycles resulting in large egg/embryo numbers, thus permitting prospectively alternative embryo assignments to EmbryoScope™ and standard Embryology. We then compared pregnancy rates and embryo quality on day-3 after fertilization and embryologist time utilized per processed embryo. Part A revealed in poor prognosis patients no differences in day-3 embryo scores, implantation and clinical pregnancy rates between EmbryoScope™ and standard Embryology. The EmbryoScope™, however, more than doubled Embryology staff time (P < 0.0001). In Part B, embryos grown in the EmbyoScope™ demonstrated significantly poorer day-3 quality (depending on embryo parameter between P = 0.005 and P = 0.01). Suspicion that conical culture dishes of the EmbryoScope™ (EmbryoSlide™) may be the cause was disproven when standard culture dishes demonstrated no outcome difference in standard incubation. Though due to small patient numbers preliminary, this study raises concerns about the mostly uncontrolled introduction of closed incubation systems with time lapse imaging into routine clinical Embryology. Appropriately designed and powered prospectively randomized studies appear urgently needed in well-defined patient populations before the uncontrolled utilization of these instruments further expands. NCT02246309 Registered September 18, 2014.
Gabor Vajta - One of the best experts on this subject based on the ideXlab platform.
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vitrification in human and domestic animal Embryology work in progress
Reproduction Fertility and Development, 2013Co-Authors: Gabor VajtaAbstract:According to the analysis of papers published in major international journals, rapidly increasing application of vitrification is one of the greatest achievements in domestic animal and especially human Embryology during the first decade of our century. This review highlights factors supporting or hampering this progress, summarises results achieved with vitrification and outlines future tasks to fully exploit the benefits of this amazing approach that has changed or will change many aspects of laboratory (and also clinical) Embryology. Supporting factors include the simplicity, cost efficiency and convincing success of vitrification compared with other approaches in all species and developmental stages in mammalian Embryology, while causes that slow down the progress are mostly of human origin: inadequate tools and solutions, superficial teaching, improper application and unjustified concerns resulting in legal restrictions. Elimination of these hindrances seems to be a slower process and more demanding task than meeting the biological challenge. A key element of future progress will be to pass the pioneer age, establish a consensus regarding biosafety requirements, outline the indispensable features of a standard approach and design fully-automated vitrification machines executing all phases of the procedure, including equilibration, cooling, warming and dilution steps.
Hisami Ando - One of the best experts on this subject based on the ideXlab platform.
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Embryology of the biliary tract
Digestive Surgery, 2010Co-Authors: Hisami AndoAbstract:A hepatic diverticulum appears in the ventral wall of the primitive midgut early in the 4th week of intrauterine life in the development of the human embryo. This small diverticulum is the anlage for
