The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform

Manuel D Cerqueira - One of the best experts on this subject based on the ideXlab platform.

Robert C Hendel - One of the best experts on this subject based on the ideXlab platform.

  • impact of appropriate use on the prognostic value of single photon Emission Computed Tomography myocardial perfusion imaging
    Circulation, 2013
    Co-Authors: Rami Doukky, Kathleen Hayes, Nathan Frogge, Gautam Balakrishnan, Venkata Satish Dontaraju, Maria Octavia Rangel, Yasmeen Golzar, Enrique Garciasayan, Robert C Hendel
    Abstract:

    Background—Appropriate use criteria (AUC) have been developed to aid in the optimal use of single-photon Emission Computed Tomography (SPECT)–myocardial perfusion imaging (MPI), a technique that is a mainstay of risk assessment for ischemic heart disease. The impact of appropriate use on the prognostic value of SPECT-MPI is unknown. Methods and Results—A prospective cohort study of 1511 consecutive patients undergoing outpatient, community-based SPECT-MPI was conducted. Subjects were stratified on the basis of the 2009 AUC for SPECT-MPI into an appropriate or uncertain appropriateness group and an inappropriate group. Patients were prospectively followed up for 27±10 months for major adverse cardiac events of death, death or myocardial infarction, and cardiac death or myocardial infarction. In the entire cohort, the 167 subjects (11%) with an abnormal scan experienced significantly higher rates of major adverse cardiac events and coronary revascularization than those with normal MPI. Among the 823 subject...

  • single photon Emission Computed Tomography
    Journal of Nuclear Cardiology, 2010
    Co-Authors: Thomas A Holly, Edward P. Ficaro, Brian G Abbott, Mouaz H Almallah, Dennis A Calnon, Mylan C Cohen, Frank P Difilippo, Michael R Freeman, Robert C Hendel, Diwakar Jain
    Abstract:

    Publisher Summary This chapter discusses single photon Emission Computed Tomography. The development of single photon Emission Computed Tomography (SPECT) put a powerful physiologic imaging technology in the hands of physicians and researchers. SPECT is neither as expensive nor as complex as positron Emission Tomography (PET) and can be used for many of the same purposes. Cone beam or neurofocal collimation is the most advanced collimator adaptation of the rotating gamma camera to neuro-SPECT. With a two-axis converging collimator rotating about the patient's head, the sensitivity to radiation can be two to four times that of parallel or slant collimators. Resolution approaches 10 mm FWHM. A difficult problem in SPECT imaging is correcting for scatter. The energy window used for photon discrimination includes some off-axis, Comptom-scattered radiation that is back-projected as noise into the reconstructed image along with legitimate, on-axis photons. The deeper inside any scattering material the target image is, the worse the effect is on image resolution. Several schemes are used to compensate for this effect. Labeled-antibody SPECT—with implications for beta and gamma emitter therapy in some cases—is a wide-open field limited only by the nonspecific binding of some antibody preparations. With continuing investigation, more specific agents may become available.

  • initial clinical experience with regadenoson a novel selective a2aagonist for pharmacologic stress single photon Emission Computed Tomography myocardial perfusion imaging
    Journal of the American College of Cardiology, 2005
    Co-Authors: Robert C Hendel, Ami E. Iskandrian, Manuel D Cerqueira, Timothy M Bateman, Jeffrey A Leppo, Brent Blackburn, John J Mahmarian
    Abstract:

    Initial Clinical Experience With Regadenoson, a Novel Selective A2AAgonist for Pharmacologic Stress Single-Photon Emission Computed Tomography Myocardial Perfusion ImagingRobert C. Hendel, Timothy ...

  • accf asnc appropriateness criteria for single photon Emission Computed Tomography myocardial perfusion imaging spect mpi a report of the american college of cardiology foundation quality strategic directions committee appropriateness criteria working
    Journal of the American College of Cardiology, 2005
    Co-Authors: Ralph G Brindis, Robert C Hendel, Timothy M Bateman, Pamela S Douglas, Eric D Peterson, Michael J Wolk, Joseph M Allen, Manesh R Patel, Ira E Raskin, Manuel D Cerqueira
    Abstract:

    Under the auspices of the American College of Cardiology Foundation (ACCF) and the American Society of Nuclear Cardiology (ASNC), an appropriateness review was conducted for radionuclide cardiovascular imaging (RNI), specifically gated single-photon Emission Computed Tomography myocardial perfusion

Mario Cesarelli - One of the best experts on this subject based on the ideXlab platform.

Joseph C Wu - One of the best experts on this subject based on the ideXlab platform.

Salvador Borgesneto - One of the best experts on this subject based on the ideXlab platform.