The Experts below are selected from a list of 264 Experts worldwide ranked by ideXlab platform

William A. Petri - One of the best experts on this subject based on the ideXlab platform.

  • Pathogenisis and Immunity to Entamoeba Histolytica
    World Class Parasites, 2020
    Co-Authors: Jessica L. Tarleton, William A. Petri
    Abstract:

    Diseases caused by the parasite Entamoeba Histolytica disproportionately affect residents of underdeveloped areas, afflicting places lacking sufficient sanitation, hygiene, and water processing especially. While the recent differentiation between Entamoeba Histolytica and the morphologically identical but completely asymptomatic Entamoeba dispar based on genetic and biochemical analyses has enhanced the study of the disease-causing parasite, a mystery still exists as to the factors which still cause about 90% of Entamoeba Histolytica infections to remain asymptomatic after colonization. Researchers delving into these areas have identified several features of the parasite—including the galactose and N-acetylgalactosamine inhibitable adherence lectin, proteinases, and amoebapores, all virulence factors in Entamoeba—and of the host, including the association of anti-lectin IgA with resistance to disease, which may determine whether infection is invasive. As specific and easy diagnostics are developed to aid in identifying more precisely the health burden caused by E. Histolytica, vaccine candidates are under evaluation.

  • Proteomic analysis of the cyst stage of Entamoeba Histolytica.
    PLOS Neglected Tropical Diseases, 2012
    Co-Authors: Rashidul Haque, Mamun Kabir, Abdullah Siddique, Nicholas E. Sherman, Sean A. Gray, Gerard A. Cangelosi, William A. Petri
    Abstract:

    Background The category B agent of bioterrorism, Entamoeba Histolytica has a two-stage life cycle: an infective cyst stage, and an invasive trophozoite stage. Due to our inability to effectively induce encystation in vitro, our knowledge about the cyst form remains limited. This also hampers our ability to develop cyst-specific diagnostic tools.

  • leptin signaling in intestinal epithelium mediates resistance to enteric infection by Entamoeba Histolytica
    Mucosal Immunology, 2011
    Co-Authors: Margo R Roberts, Stephen M Becker, Bradley S Podd, Yiying Zhang, Streamson C Chua, Martin G Myers, Priya Duggal, Eric R Houpt, William A. Petri
    Abstract:

    Leptin signaling in intestinal epithelium mediates resistance to enteric infection by Entamoeba Histolytica

  • Short hairpin RNA-mediated knockdown of protein expression in Entamoeba Histolytica
    BMC Microbiology, 2009
    Co-Authors: Alicia S. Linford, Heriberto Moreno, Katelyn R Good, Hanbang Zhang, Upinder Singh, William A. Petri
    Abstract:

    Background Entamoeba Histolytica is an intestinal protozoan parasite of humans. The genome has been sequenced, but the study of individual gene products has been hampered by the lack of the ability to generate gene knockouts. We chose to test the use of RNA interference to knock down gene expression in Entamoeba Histolytica.

  • Comparison of two immunoassays for detection of Entamoeba Histolytica.
    Journal of Clinical Microbiology, 2008
    Co-Authors: Sarah N. Buss, William A. Petri, Mamun Kabir, Rashidul Haque
    Abstract:

    Effective diagnostic tools are essential in order to combat disease caused by the parasite Entamoeba Histolytica. In this study, we compared the commercially available Ridascreen Entamoeba test (R-Biopharm) and the E. Histolytica II test (Techlab), and we found that the E. Histolytica II test detects E. Histolytica infections more accurately.

Mami Okada - One of the best experts on this subject based on the ideXlab platform.

  • proteomic analysis of phagocytosis in the enteric protozoan parasite Entamoeba Histolytica
    Eukaryotic Cell, 2005
    Co-Authors: William A. Petri, Christopher D. Huston, Barbara J. Mann, Mami Okada, Kiyoshi Kita, Tomoyoshi Nozaki
    Abstract:

    Proteomic analysis of phagosomes isolated from Entamoeba Histolytica by liquid chromatography and mass spectrometry identified 85 proteins involved in surface recognition, actin cytoskeleton rearrangement, vesicular trafficking, and degradation. Phagosome localization of representative proteins was verified by immunofluorescence assay. This study should provide a basis for molecular identification and characterization of phagosome biogenesis.

Tomoyoshi Nozaki - One of the best experts on this subject based on the ideXlab platform.

Kurtuluş Aksu - One of the best experts on this subject based on the ideXlab platform.

  • Entamoeba Histolytica and urticaria
    Ankara Medical Journal, 2016
    Co-Authors: Kurtuluş Aksu
    Abstract:

    Dear Editor, I have read the article “Chronic spontaneous urticaria and internal parasites–a systematic review” written by Kolkhir P et al published in Allergy with great interest and benefited information regarding possible relationship between parasitic infections and chronic spontaneous urticaria in Turkey. 1 In this article it is mentioned that Blastocystishominis and Giardia spp are related to chronic spontaneous urticaria (CSU) in Turkey. Entamoeba Histolytica, on the contrary, is blamed to be responsible for this pathology only in one report from India. As mentioned in this article, Entamoeba Histolytica, which is the third most common cause of parasitic infections, is the most common cause of CSU in adults.  We have recently published a report on coexistence of urticaria and Entamoeba Histolytica in your journal. 2 Among 188 patients diagnosed with urticaria in our Immunology and Allergy Clinic between July 2013 and April 2014, routine microscopic stool examinations revealed positive results in four specimens. These four specimens were positive for Entamoeba Histolytica resulting in an incidence of 2.1%. In this context, we think that parasitic infections should be concerned in all patients with CSU; however, this issue should be evaluated more closely and responsible microorganisms as to the basis of countries should be investigated with epidemiological studies.

  • Urticaria and Entamoeba Histolytica Association: Report of Four Cases
    Ankara Medical Journal, 2016
    Co-Authors: Ayşe Demirci Şahin, Kurtuluş Aksu
    Abstract:

    Urticaria affects 15-25% of people at least once in their life time. There is limited research about urticaria relations of parasitosis, the majority consisting of case reports. Current studies show that other parasitic infections are more frequently observed in the etiology of urticaria, whereas the incidence of Entamoeba Histolytica is quite low. Here we present four recent cases of Entamoeba Histolytica which its diagnosis was made in routine stool microscopy in urticaria. Three patients had no gastrointestinal symptoms, by the treatment of Entamoeba Histolytica three patients’ urticaria have regressed, one patient was referred to the infectious diseases clinic because of chronic renal failure.

Kiyoshi Kita - One of the best experts on this subject based on the ideXlab platform.

  • proteomic analysis of phagocytosis in the enteric protozoan parasite Entamoeba Histolytica
    Eukaryotic Cell, 2005
    Co-Authors: William A. Petri, Christopher D. Huston, Barbara J. Mann, Mami Okada, Kiyoshi Kita, Tomoyoshi Nozaki
    Abstract:

    Proteomic analysis of phagosomes isolated from Entamoeba Histolytica by liquid chromatography and mass spectrometry identified 85 proteins involved in surface recognition, actin cytoskeleton rearrangement, vesicular trafficking, and degradation. Phagosome localization of representative proteins was verified by immunofluorescence assay. This study should provide a basis for molecular identification and characterization of phagosome biogenesis.