The Experts below are selected from a list of 264 Experts worldwide ranked by ideXlab platform
Giuseppe Vitiello - One of the best experts on this subject based on the ideXlab platform.
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water bridging dynamics of polymerase chain reaction in the gauge theory paradigm of quantum fields
arXiv: Other Quantitative Biology, 2018Co-Authors: Luc Montagnier, Patricia Romano, T. J.a. Craddock, Angela Capolupo, P. Kurian, Anthony Polcari, Jamal Aissa, Claude Lavallee, Alberto Tedeschi, Giuseppe VitielloAbstract:We discuss the role of water bridging the DNA-Enzyme Interaction by resorting to recent results showing that London dispersion forces between delocalized electrons of base pairs of DNA are responsible for the formation of dipole modes that can be recognized by \textit{Taq} polymerase. We describe the dynamic origin of the high efficiency and precise targeting of \textit{Taq} activity in PCR. The spatiotemporal distribution of Interaction couplings, frequencies, amplitudes, and phase modulations comprise a pattern of fields which constitutes the electromagnetic image of DNA in the surrounding water, which is what the polymerase Enzyme actually recognizes in the DNA water environment. The experimental realization of PCR amplification, achieved through replacement of the DNA template by the treatment of pure water with electromagnetic signals recorded from viral and bacterial DNA solutions, is found consistent with the gauge theory paradigm of quantum fields.
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Water bridging dynamics of polymerase chain reaction in the gauge theory paradigm of quantum fields
Water (Switzerland), 2017Co-Authors: Luc Montagnier, Antonio Tedeschi, Patricia Romano, T. J.a. Craddock, Joel Aissa, Angela Capolupo, Christian Lavallee, P. Kurian, Anthony Polcari, Giuseppe VitielloAbstract:We discuss the role of water bridging the DNA-Enzyme Interaction by resorting to recent results showing that London dispersion forces between delocalized electrons of base pairs of DNA are responsible for the formation of dipole modes that can be recognized by Taq polymerase. We describe the dynamic origin of the high efficiency and precise targeting of Taq activity in PCR. The spatiotemporal distribution of Interaction couplings, frequencies, amplitudes, and phase modulations comprise a pattern of fields which constitutes the electromagnetic image of DNA in the surrounding water, which is what the polymerase Enzyme actually recognizes in the DNA water environment. The experimental realization of PCR amplification, achieved through replacement of the DNA template by the treatment of pure water with electromagnetic signals recorded from viral and bacterial DNA solutions, is found consistent with the gauge theory paradigm of quantum fields.
Luc Montagnier - One of the best experts on this subject based on the ideXlab platform.
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water bridging dynamics of polymerase chain reaction in the gauge theory paradigm of quantum fields
arXiv: Other Quantitative Biology, 2018Co-Authors: Luc Montagnier, Patricia Romano, T. J.a. Craddock, Angela Capolupo, P. Kurian, Anthony Polcari, Jamal Aissa, Claude Lavallee, Alberto Tedeschi, Giuseppe VitielloAbstract:We discuss the role of water bridging the DNA-Enzyme Interaction by resorting to recent results showing that London dispersion forces between delocalized electrons of base pairs of DNA are responsible for the formation of dipole modes that can be recognized by \textit{Taq} polymerase. We describe the dynamic origin of the high efficiency and precise targeting of \textit{Taq} activity in PCR. The spatiotemporal distribution of Interaction couplings, frequencies, amplitudes, and phase modulations comprise a pattern of fields which constitutes the electromagnetic image of DNA in the surrounding water, which is what the polymerase Enzyme actually recognizes in the DNA water environment. The experimental realization of PCR amplification, achieved through replacement of the DNA template by the treatment of pure water with electromagnetic signals recorded from viral and bacterial DNA solutions, is found consistent with the gauge theory paradigm of quantum fields.
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Water bridging dynamics of polymerase chain reaction in the gauge theory paradigm of quantum fields
Water (Switzerland), 2017Co-Authors: Luc Montagnier, Antonio Tedeschi, Patricia Romano, T. J.a. Craddock, Joel Aissa, Angela Capolupo, Christian Lavallee, P. Kurian, Anthony Polcari, Giuseppe VitielloAbstract:We discuss the role of water bridging the DNA-Enzyme Interaction by resorting to recent results showing that London dispersion forces between delocalized electrons of base pairs of DNA are responsible for the formation of dipole modes that can be recognized by Taq polymerase. We describe the dynamic origin of the high efficiency and precise targeting of Taq activity in PCR. The spatiotemporal distribution of Interaction couplings, frequencies, amplitudes, and phase modulations comprise a pattern of fields which constitutes the electromagnetic image of DNA in the surrounding water, which is what the polymerase Enzyme actually recognizes in the DNA water environment. The experimental realization of PCR amplification, achieved through replacement of the DNA template by the treatment of pure water with electromagnetic signals recorded from viral and bacterial DNA solutions, is found consistent with the gauge theory paradigm of quantum fields.
Yudong Cai - One of the best experts on this subject based on the ideXlab platform.
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prediction of Interaction between small molecule and Enzyme using adaboost
Molecular Diversity, 2009Co-Authors: Bing Niu, Yuhuan Jin, Kaiyan Fen, Yudong CaiAbstract:The knowledge of whether one Enzyme can interact with a small molecule is essential for understanding the molecular and cellular functions of organisms. In this paper, we introduce a classifier to predict the small molecule– Enzyme Interaction, i.e., whether they can interact with each other. Small molecules are represented by their chemical functional groups, and Enzymes are represented by their biochemical and physicochemical properties, resulting in a total of 160 features. These features are input into the AdaBoost classifier, which is known to have good generalization ability to predict Interaction. As a result, the overall prediction accuracy, tested by tenfold cross-validation and independent sets, is 81.76% and 83.35%, respectively, suggesting that this strategy is effective. In this research, we typically choose Interactions between small molecules and Enzymes involved in metabolism to ultimately improve further understanding of metabolic pathways. An online predictor developed by this research is available at http://chemdata.shu.edu.cn/small_m.
P. Kurian - One of the best experts on this subject based on the ideXlab platform.
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water bridging dynamics of polymerase chain reaction in the gauge theory paradigm of quantum fields
arXiv: Other Quantitative Biology, 2018Co-Authors: Luc Montagnier, Patricia Romano, T. J.a. Craddock, Angela Capolupo, P. Kurian, Anthony Polcari, Jamal Aissa, Claude Lavallee, Alberto Tedeschi, Giuseppe VitielloAbstract:We discuss the role of water bridging the DNA-Enzyme Interaction by resorting to recent results showing that London dispersion forces between delocalized electrons of base pairs of DNA are responsible for the formation of dipole modes that can be recognized by \textit{Taq} polymerase. We describe the dynamic origin of the high efficiency and precise targeting of \textit{Taq} activity in PCR. The spatiotemporal distribution of Interaction couplings, frequencies, amplitudes, and phase modulations comprise a pattern of fields which constitutes the electromagnetic image of DNA in the surrounding water, which is what the polymerase Enzyme actually recognizes in the DNA water environment. The experimental realization of PCR amplification, achieved through replacement of the DNA template by the treatment of pure water with electromagnetic signals recorded from viral and bacterial DNA solutions, is found consistent with the gauge theory paradigm of quantum fields.
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Water bridging dynamics of polymerase chain reaction in the gauge theory paradigm of quantum fields
Water (Switzerland), 2017Co-Authors: Luc Montagnier, Antonio Tedeschi, Patricia Romano, T. J.a. Craddock, Joel Aissa, Angela Capolupo, Christian Lavallee, P. Kurian, Anthony Polcari, Giuseppe VitielloAbstract:We discuss the role of water bridging the DNA-Enzyme Interaction by resorting to recent results showing that London dispersion forces between delocalized electrons of base pairs of DNA are responsible for the formation of dipole modes that can be recognized by Taq polymerase. We describe the dynamic origin of the high efficiency and precise targeting of Taq activity in PCR. The spatiotemporal distribution of Interaction couplings, frequencies, amplitudes, and phase modulations comprise a pattern of fields which constitutes the electromagnetic image of DNA in the surrounding water, which is what the polymerase Enzyme actually recognizes in the DNA water environment. The experimental realization of PCR amplification, achieved through replacement of the DNA template by the treatment of pure water with electromagnetic signals recorded from viral and bacterial DNA solutions, is found consistent with the gauge theory paradigm of quantum fields.
Patricia Romano - One of the best experts on this subject based on the ideXlab platform.
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water bridging dynamics of polymerase chain reaction in the gauge theory paradigm of quantum fields
arXiv: Other Quantitative Biology, 2018Co-Authors: Luc Montagnier, Patricia Romano, T. J.a. Craddock, Angela Capolupo, P. Kurian, Anthony Polcari, Jamal Aissa, Claude Lavallee, Alberto Tedeschi, Giuseppe VitielloAbstract:We discuss the role of water bridging the DNA-Enzyme Interaction by resorting to recent results showing that London dispersion forces between delocalized electrons of base pairs of DNA are responsible for the formation of dipole modes that can be recognized by \textit{Taq} polymerase. We describe the dynamic origin of the high efficiency and precise targeting of \textit{Taq} activity in PCR. The spatiotemporal distribution of Interaction couplings, frequencies, amplitudes, and phase modulations comprise a pattern of fields which constitutes the electromagnetic image of DNA in the surrounding water, which is what the polymerase Enzyme actually recognizes in the DNA water environment. The experimental realization of PCR amplification, achieved through replacement of the DNA template by the treatment of pure water with electromagnetic signals recorded from viral and bacterial DNA solutions, is found consistent with the gauge theory paradigm of quantum fields.
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Water bridging dynamics of polymerase chain reaction in the gauge theory paradigm of quantum fields
Water (Switzerland), 2017Co-Authors: Luc Montagnier, Antonio Tedeschi, Patricia Romano, T. J.a. Craddock, Joel Aissa, Angela Capolupo, Christian Lavallee, P. Kurian, Anthony Polcari, Giuseppe VitielloAbstract:We discuss the role of water bridging the DNA-Enzyme Interaction by resorting to recent results showing that London dispersion forces between delocalized electrons of base pairs of DNA are responsible for the formation of dipole modes that can be recognized by Taq polymerase. We describe the dynamic origin of the high efficiency and precise targeting of Taq activity in PCR. The spatiotemporal distribution of Interaction couplings, frequencies, amplitudes, and phase modulations comprise a pattern of fields which constitutes the electromagnetic image of DNA in the surrounding water, which is what the polymerase Enzyme actually recognizes in the DNA water environment. The experimental realization of PCR amplification, achieved through replacement of the DNA template by the treatment of pure water with electromagnetic signals recorded from viral and bacterial DNA solutions, is found consistent with the gauge theory paradigm of quantum fields.