The Experts below are selected from a list of 1566 Experts worldwide ranked by ideXlab platform
Stephen J. Gluckman - One of the best experts on this subject based on the ideXlab platform.
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Eosinophilic Meningitis.
The American Journal of Medicine, 2003Co-Authors: Stephen J. GluckmanAbstract:Eosinophilic Meningitis is a rare clinical entity that can be useful in narrowing the differential diagnosis of central nervous system disease. It is defined by the presence of 10 or more eosinophils/microL in the cerebrospinal fluid (CSF) or a CSF eosinophilia of at least 10%. The most common cause is invasion of the central nervous system by helminthic parasites, particularly Angiostrongylus cantonensis, but other infections as well as noninfectious conditions may also be associated. This review describes the etiologies of Eosinophilic Meningitis, focusing primarily on the helminths that cause CSF eosinophilia.
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Eosinophilic Meningitis due to gnathostoma spinigerum
Journal of Infection, 2002Co-Authors: Lo V Re, Stephen J. GluckmanAbstract:We present a case of Eosinophilic Meningitis due to the tissue nematode Gnathostoma spinigerum in a patient with remote travel to Korea. G. spinigerum is found primarily in Southeast Asia, but cases are being increasingly diagnosed in non-endemic areas because of more extensive international travel. The organism has been known to persist in human tissues for over a decade, so earlier travel to endemic areas is important.
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Eosinophilic Meningitis due to angiostrongylus cantonensis in a returned traveler case report and review of the literature
Clinical Infectious Diseases, 2001Co-Authors: Vincent Lo Re, Stephen J. GluckmanAbstract:Angiostrongylus cantonensis, the rat lungworm, is the principal cause of Eosinophilic Meningitis worldwide, and the increase in world travel and shipborne dispersal of infected rat vectors has extended this parasite to regions outside of its traditional geographic boundaries. We report a case of Eosinophilic Meningitis due to A. cantonensis in a patient who recently returned from a trip in the Pacific. Eosinophilic pleocytosis in the CSF is an uncommon finding that most often results from helminthic infection of the CNS [1]. Angiostrongylus cantonensis, the nematode lungworm in rats, is the principal cause of Eosinophilic Meningitis worldwide [2]. It occurs predominantly in Southeast Asia and throughout the Pacific basin [3]. However, with the increase in world travel and the shipborne dispersal of infected rats, the parasite has been extending its range [4]. Cases of A. cantonensis infection have been reported in Australia [5] and, more recently, in North America [6]. Although the parasite has begun to garner attention as an emerging infectious disease, clinical awareness remains low. The diagnosis should always be considered for a patient with subacute Meningitis, particularly if there is CSF eosinophilia or if the patient has traveled to an area of endemicity. We report a case of Eosinophilic Meningitis due to A. cantonensis in a traveler who had recently returned from a trip to the Pacific basin. Case report. A 37-year-old woman presented to our hospital with a 4-week history of severe headaches, paresthesias, and diminished hearing in her left ear. The patient was pre
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Eosinophilic Meningitis Due to Angiostrongylus cantonensis in a Returned Traveler: Case Report and Review of the Literature
Clinical Infectious Diseases, 2001Co-Authors: Stephen J. GluckmanAbstract:Angiostrongylus cantonensis, the rat lungworm, is the principal cause of Eosinophilic Meningitis worldwide, and the increase in world travel and shipborne dispersal of infected rat vectors has extended this parasite to regions outside of its traditional geographic boundaries. We report a case of Eosinophilic Meningitis due to A. cantonensis in a patient who recently returned from a trip in the Pacific.
M Rothen - One of the best experts on this subject based on the ideXlab platform.
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Eosinophilic Meningitis due to angiostrongylus cantonensis in switzerland
Infection, 2004Co-Authors: E Bartschi, Gerard Bordmann, J Blum, M RothenAbstract:: Eosinophilic Meningitis is a well-known disease in areas where the rat lung worm Angiostrongylus cantonensis is endemic, i.e. in Southeast Asia and in the Caribbean. We report a case of Eosinophilic Meningitis due to infection with Angiostrongylus cantonensis in a traveler returning from Cuba. The diagnosis was based upon symptoms of chronic Meningitis associated with hyperesthesia and presence of eosinophilia in the cerebrospinal fluid. With increasing mobility rare infections like Eosinophilic Meningitis due to A. cantonensis may be encountered in the western hemisphere. A Giemsa stain of the cerebrospinal fluid is crucial for a prompt diagnosis that is confirmed by detection of specific antibodies.
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Eosinophilic Meningitis Due to Angiostrongylus cantonensis in Switzerland
Infection, 2004Co-Authors: E Bartschi, Gerard Bordmann, J Blum, M RothenAbstract:Eosinophilic Meningitis is a well-known disease in areas where the rat lung worm Angiostrongylus cantonensis is endemic, i.e. in Southeast Asia and in the Caribbean. We report a case of Eosinophilic Meningitis due to infection with Angiostrongylus cantonensis in a traveler returning from Cuba. The diagnosis was based upon symptoms of chronic Meningitis associated with hyperesthesia and presence of eosinophilia in the cerebrospinal fluid. With increasing mobility rare infections like Eosinophilic Meningitis due to A. cantonensis may be encountered in the western hemisphere. A Giemsa stain of the cerebrospinal fluid is crucial for a prompt diagnosis that is confirmed by detection of specific antibodies.
Kittisak Sawanyawisuth - One of the best experts on this subject based on the ideXlab platform.
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clinical manifestations of Eosinophilic Meningitis due to infection with angiostrongylus cantonensis in children
Korean Journal of Parasitology, 2013Co-Authors: Kittisak Sawanyawisuth, Verajit Chotmongkol, Panita Limpawattana, Jarin Chindaprasirt, Vichai Senthong, Narong Auvichayapat, Sompon Tassniyom, Wanchai Maleewong, Pewpan M. IntapanAbstract:Eosinophilic Meningitis, caused by the nematode Angiostrongylus cantonensis, is prevalent in northeastern Thailand, most commonly in adults. Data regarding clinical manifestations of this condition in children is limited and may be different those in adults. A chart review was done on 19 Eosinophilic Meningitis patients aged less than 15 years in Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Thailand. Clinical manifestations and outcomes were reported using descriptive statistics. All patients had presented with severe headache. Most patients were males, had fever, nausea or vomiting, stiffness of the neck, and a history of snail ingestion. Six patients had papilledema or cranial nerve palsies. It was shown that the clinical manifestations of Eosinophilic Meningitis due to A. cantonensis in children are different from those in adult patients. Fever, nausea, vomiting, hepatomegaly, neck stiffness, and cranial nerve palsies were all more common in children than in adults.
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Chapter 15 – Eosinophilic Meningitis
Neuroparasitology and Tropical Neurology, 2013Co-Authors: Kittisak Sawanyawisuth, Verajit ChotmongkolAbstract:Eosinophilic Meningitis is defined by the presence of at least 10% eosinophils in the total cerebrospinal fluid (CSF) leukocyte count. Although there are several possible causes of eosinophils in the CSF, parasitic infection is the main cause. The three common parasites causing Eosinophilic Meningitis include Angiostrongylus cantonensis, Gnathostoma spinigerum, and Taenia solium. Even though these parasites are endemic in tropical countries, they are now spreading globally due to extensive traveling, and physicians worldwide should pay more attention to this condition. This chapter will review risk factors, clinical manifestations, and treatment of these three parasites.
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chapter 15 Eosinophilic Meningitis
Handbook of Clinical Neurology, 2013Co-Authors: Kittisak Sawanyawisuth, Verajit ChotmongkolAbstract:Eosinophilic Meningitis is defined by the presence of at least 10% eosinophils in the total cerebrospinal fluid (CSF) leukocyte count. Although there are several possible causes of eosinophils in the CSF, parasitic infection is the main cause. The three common parasites causing Eosinophilic Meningitis include Angiostrongylus cantonensis, Gnathostoma spinigerum, and Taenia solium. Even though these parasites are endemic in tropical countries, they are now spreading globally due to extensive traveling, and physicians worldwide should pay more attention to this condition. This chapter will review risk factors, clinical manifestations, and treatment of these three parasites.
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Drug target in Eosinophilic Meningitis caused by Angiostrongylus cantonensis.
Infectious disorders drug targets, 2010Co-Authors: Kittisak SawanyawisuthAbstract:: Eosinophilic Meningitis caused by Angiostrongylus cantonensis is an emerging infectious disease. It is the most common form of human angiostrongyliasis. The diagnosis is made by clinical criteria including the presence of cerebrospinal fluid eosinophils and a history of exposure to A. cantonensis larvae, e.g., from raw freshwater snails or contaminated vegetables. Among various treatment options, corticosteroid is the only effective treatment.
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Drug target in Eosinophilic Meningitis caused by Angiostrongylus cantonensis.
Infectious disorders drug targets, 2010Co-Authors: Kittisak SawanyawisuthAbstract:: Eosinophilic Meningitis caused by Angiostrongylus cantonensis is an emerging infectious disease. It is the most common form of human angiostrongyliasis. The diagnosis is made by clinical criteria including the presence of cerebrospinal fluid eosinophils and a history of exposure to A. cantonensis larvae, e.g., from raw freshwater snails or contaminated vegetables. Among various treatment options, corticosteroid is the only effective treatment.
Verajit Chotmongkol - One of the best experts on this subject based on the ideXlab platform.
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clinical manifestations of Eosinophilic Meningitis due to infection with angiostrongylus cantonensis in children
Korean Journal of Parasitology, 2013Co-Authors: Kittisak Sawanyawisuth, Verajit Chotmongkol, Panita Limpawattana, Jarin Chindaprasirt, Vichai Senthong, Narong Auvichayapat, Sompon Tassniyom, Wanchai Maleewong, Pewpan M. IntapanAbstract:Eosinophilic Meningitis, caused by the nematode Angiostrongylus cantonensis, is prevalent in northeastern Thailand, most commonly in adults. Data regarding clinical manifestations of this condition in children is limited and may be different those in adults. A chart review was done on 19 Eosinophilic Meningitis patients aged less than 15 years in Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Thailand. Clinical manifestations and outcomes were reported using descriptive statistics. All patients had presented with severe headache. Most patients were males, had fever, nausea or vomiting, stiffness of the neck, and a history of snail ingestion. Six patients had papilledema or cranial nerve palsies. It was shown that the clinical manifestations of Eosinophilic Meningitis due to A. cantonensis in children are different from those in adult patients. Fever, nausea, vomiting, hepatomegaly, neck stiffness, and cranial nerve palsies were all more common in children than in adults.
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Chapter 15 – Eosinophilic Meningitis
Neuroparasitology and Tropical Neurology, 2013Co-Authors: Kittisak Sawanyawisuth, Verajit ChotmongkolAbstract:Eosinophilic Meningitis is defined by the presence of at least 10% eosinophils in the total cerebrospinal fluid (CSF) leukocyte count. Although there are several possible causes of eosinophils in the CSF, parasitic infection is the main cause. The three common parasites causing Eosinophilic Meningitis include Angiostrongylus cantonensis, Gnathostoma spinigerum, and Taenia solium. Even though these parasites are endemic in tropical countries, they are now spreading globally due to extensive traveling, and physicians worldwide should pay more attention to this condition. This chapter will review risk factors, clinical manifestations, and treatment of these three parasites.
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chapter 15 Eosinophilic Meningitis
Handbook of Clinical Neurology, 2013Co-Authors: Kittisak Sawanyawisuth, Verajit ChotmongkolAbstract:Eosinophilic Meningitis is defined by the presence of at least 10% eosinophils in the total cerebrospinal fluid (CSF) leukocyte count. Although there are several possible causes of eosinophils in the CSF, parasitic infection is the main cause. The three common parasites causing Eosinophilic Meningitis include Angiostrongylus cantonensis, Gnathostoma spinigerum, and Taenia solium. Even though these parasites are endemic in tropical countries, they are now spreading globally due to extensive traveling, and physicians worldwide should pay more attention to this condition. This chapter will review risk factors, clinical manifestations, and treatment of these three parasites.
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Comparison of prednisolone plus albendazole with prednisolone alone for treatment of patients with Eosinophilic Meningitis.
The American Journal of Tropical Medicine and Hygiene, 2009Co-Authors: Verajit Chotmongkol, Suvicha Kittimongkolma, Pewpan M. Intapan, Kanigar Niwattayakul, Yupa ThavornpitakAbstract:Corticosteroid and the combination of corticosteroid and antihelminthic drug are safe and beneficial in relieving headaches in patients with Eosinophilic Meningitis. However, clinical trials comparing the efficacies of these regimens have never been reported. We conducted a prospective, open, randomized, controlled study to compare the efficacy of the combination of prednisolone plus albendazole and prednisolone alone for the treatment of Eosinophilic Meningitis. Our study had 53 patients in the combined treatment group and 51 patients in the prednisolone alone group. There were no significant differences between the two groups with regard to the number of patients who still had headaches after 14 days (0 versus 1, respectively; P = 0.49) and the median length of time until complete disappearance of headache (3 versus 3 days, respectively; P = 0.32. Prednisolone plus albendazole is no better than prednisolone alone for treatment of patients with Eosinophilic Meningitis.
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Treatment of Eosinophilic Meningitis with a combination of prednisolone and mebendazole.
The American Journal of Tropical Medicine and Hygiene, 2006Co-Authors: Verajit Chotmongkol, Kittisak Sawanyawisuth, Kookwan Sawadpanitch, Sitichoke Louhawilai, Panita LimpawattanaAbstract:To study the efficacy of the combination of prednisolone and mebendazole for the treatment of Eosinophilic Meningitis, we conducted a pilot study among Thai patients with Eosinophilic Meningitis. Patients were given a two-week course of prednisolone, 60 mg/day, and mebendazole, 10 mg/kg/day. The primary observation parameter was the number of patients who still had headaches after the two-week course of treatment. Forty-one patients were enrolled in the study. Four (10%) patients still had headaches after the two-week course of treatment and the median length of time until complete disappearance of headaches was three days. Serious side effects were not detected. Treatment for two weeks with the combination regimen of prednisolone and mebendazole is safe and beneficial in relieving headaches in patients with Eosinophilic Meningitis.
E Bartschi - One of the best experts on this subject based on the ideXlab platform.
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Eosinophilic Meningitis due to angiostrongylus cantonensis in switzerland
Infection, 2004Co-Authors: E Bartschi, Gerard Bordmann, J Blum, M RothenAbstract:: Eosinophilic Meningitis is a well-known disease in areas where the rat lung worm Angiostrongylus cantonensis is endemic, i.e. in Southeast Asia and in the Caribbean. We report a case of Eosinophilic Meningitis due to infection with Angiostrongylus cantonensis in a traveler returning from Cuba. The diagnosis was based upon symptoms of chronic Meningitis associated with hyperesthesia and presence of eosinophilia in the cerebrospinal fluid. With increasing mobility rare infections like Eosinophilic Meningitis due to A. cantonensis may be encountered in the western hemisphere. A Giemsa stain of the cerebrospinal fluid is crucial for a prompt diagnosis that is confirmed by detection of specific antibodies.
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Eosinophilic Meningitis Due to Angiostrongylus cantonensis in Switzerland
Infection, 2004Co-Authors: E Bartschi, Gerard Bordmann, J Blum, M RothenAbstract:Eosinophilic Meningitis is a well-known disease in areas where the rat lung worm Angiostrongylus cantonensis is endemic, i.e. in Southeast Asia and in the Caribbean. We report a case of Eosinophilic Meningitis due to infection with Angiostrongylus cantonensis in a traveler returning from Cuba. The diagnosis was based upon symptoms of chronic Meningitis associated with hyperesthesia and presence of eosinophilia in the cerebrospinal fluid. With increasing mobility rare infections like Eosinophilic Meningitis due to A. cantonensis may be encountered in the western hemisphere. A Giemsa stain of the cerebrospinal fluid is crucial for a prompt diagnosis that is confirmed by detection of specific antibodies.