The Experts below are selected from a list of 1002 Experts worldwide ranked by ideXlab platform
Ralph L. Sacco - One of the best experts on this subject based on the ideXlab platform.
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Epidemiology of Stroke in Young Adults: Race/Ethnic Differences
Journal of Thrombosis and Thrombolysis, 2005Co-Authors: Ji Y. Chong, Ralph L. SaccoAbstract:Stroke is the third leading cause of death and the leading cause of disability in the United States. Stroke incidence is clearly associated with advancing age. Although younger adults are at lower risk, Stroke in this population has a particularly high public health impact because of associated indirect costs, such as longer years of lost productivity. There have been many epidemiological studies addressing race ethnic differences in overall Stroke incidence and mortality, but few specifically examining these differences in the young adult population. There is evidence that race ethnic differences may have a greater effect on Stroke incidence and mortality in young adults. An understanding of these differences may help better identify high risk populations and focus preventative strategies. Furthermore, analysis of race/ethnic differences in Stroke subtypes may help clarify mechanisms of Stroke in young adults and potential race-ethnic differences in early Stroke risk factors.
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Epidemiology of Stroke in young adults race ethnic differences
Journal of Thrombosis and Thrombolysis, 2005Co-Authors: Ji Y. Chong, Ralph L. SaccoAbstract:Stroke is the third leading cause of death and the leading cause of disability in the United States. Stroke incidence is clearly associated with advancing age. Although younger adults are at lower risk, Stroke in this population has a particularly high public health impact because of associated indirect costs, such as longer years of lost productivity.
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Epidemiology of Stroke in young adults: race/ethnic differences.
Journal of Thrombosis and Thrombolysis, 2005Co-Authors: Ji Y. Chong, Ralph L. SaccoAbstract:Stroke is the third leading cause of death and the leading cause of disability in the United States. Stroke incidence is clearly associated with advancing age. Although younger adults are at lower risk, Stroke in this population has a particularly high public health impact because of associated indirect costs, such as longer years of lost productivity.
Ngu K Blackett - One of the best experts on this subject based on the ideXlab platform.
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the Epidemiology of Stroke in sickle cell patients in yaounde cameroon
Journal of the Neurological Sciences, 2006Co-Authors: Alfred K Njamnshi, E N Mbong, Ambroise Wonkam, Pierre Ongolozogo, Dep V Djientcheu, F L Sunjoh, Charles S Wiysonge, Roman Sztajzel, Dora Mbanya, Ngu K BlackettAbstract:Background and purpose: Stroke, a severe and recurrent but preventable complication of sickle cell disease (SCD), has not been well studied in Cameroon. To obtain baseline data towards the development of a national Stroke prevention programme in SCD, we studied a sample of sickle cell patients with the aim of determining Stroke prevalence, clinical presentation and management practices. Patients and methods: Homozygous sickle cell patients in two centres in Yaounde were screened for Stroke, in a cross-sectional study. Stroke was diagnosed clinically and confirmed where possible with brain computerized tomography. The National Institutes of Health Stroke Score (NIHSS) and modified Rankin scale (mRS) were used to assess Stroke severity. Management practices were noted from patient charts. Results: One hundred and twenty patients aged 7 months to 35 years (mean age 13.49±8.79 years) were included. Eight cases of Stroke (mean age 16.6±11.2 years) were identified, giving a Stroke prevalence of 6.67%. Cerebral infarction was thrice as common as cerebral hemorrhage and clinical presentation was classical. Cerebral infarction was more frequent in patients aged below 20 years and hemorrhage in those above 20 (p=0.11). The annual recurrence rate was 25%. Missed diagnosis rate by attending physician was 25%. The NIHSS and mRS showed high Stroke severity. Stroke management practices were insufficient and no patient received any form of Stroke prophylaxis. Conclusion: Stroke prevalence and presentation in sickle cell patients in Yaounde is similar to that observed in developed countries, but the wide management gap calls for rapid action. Our situation is ideal for the study of the natural history of Stroke in sickle cell disease.
Ji Y. Chong - One of the best experts on this subject based on the ideXlab platform.
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Epidemiology of Stroke in Young Adults: Race/Ethnic Differences
Journal of Thrombosis and Thrombolysis, 2005Co-Authors: Ji Y. Chong, Ralph L. SaccoAbstract:Stroke is the third leading cause of death and the leading cause of disability in the United States. Stroke incidence is clearly associated with advancing age. Although younger adults are at lower risk, Stroke in this population has a particularly high public health impact because of associated indirect costs, such as longer years of lost productivity. There have been many epidemiological studies addressing race ethnic differences in overall Stroke incidence and mortality, but few specifically examining these differences in the young adult population. There is evidence that race ethnic differences may have a greater effect on Stroke incidence and mortality in young adults. An understanding of these differences may help better identify high risk populations and focus preventative strategies. Furthermore, analysis of race/ethnic differences in Stroke subtypes may help clarify mechanisms of Stroke in young adults and potential race-ethnic differences in early Stroke risk factors.
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Epidemiology of Stroke in young adults race ethnic differences
Journal of Thrombosis and Thrombolysis, 2005Co-Authors: Ji Y. Chong, Ralph L. SaccoAbstract:Stroke is the third leading cause of death and the leading cause of disability in the United States. Stroke incidence is clearly associated with advancing age. Although younger adults are at lower risk, Stroke in this population has a particularly high public health impact because of associated indirect costs, such as longer years of lost productivity.
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Epidemiology of Stroke in young adults: race/ethnic differences.
Journal of Thrombosis and Thrombolysis, 2005Co-Authors: Ji Y. Chong, Ralph L. SaccoAbstract:Stroke is the third leading cause of death and the leading cause of disability in the United States. Stroke incidence is clearly associated with advancing age. Although younger adults are at lower risk, Stroke in this population has a particularly high public health impact because of associated indirect costs, such as longer years of lost productivity.
Alfred K Njamnshi - One of the best experts on this subject based on the ideXlab platform.
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the Epidemiology of Stroke in sickle cell patients in yaounde cameroon
Journal of the Neurological Sciences, 2006Co-Authors: Alfred K Njamnshi, E N Mbong, Ambroise Wonkam, Pierre Ongolozogo, Dep V Djientcheu, F L Sunjoh, Charles S Wiysonge, Roman Sztajzel, Dora Mbanya, Ngu K BlackettAbstract:Background and purpose: Stroke, a severe and recurrent but preventable complication of sickle cell disease (SCD), has not been well studied in Cameroon. To obtain baseline data towards the development of a national Stroke prevention programme in SCD, we studied a sample of sickle cell patients with the aim of determining Stroke prevalence, clinical presentation and management practices. Patients and methods: Homozygous sickle cell patients in two centres in Yaounde were screened for Stroke, in a cross-sectional study. Stroke was diagnosed clinically and confirmed where possible with brain computerized tomography. The National Institutes of Health Stroke Score (NIHSS) and modified Rankin scale (mRS) were used to assess Stroke severity. Management practices were noted from patient charts. Results: One hundred and twenty patients aged 7 months to 35 years (mean age 13.49±8.79 years) were included. Eight cases of Stroke (mean age 16.6±11.2 years) were identified, giving a Stroke prevalence of 6.67%. Cerebral infarction was thrice as common as cerebral hemorrhage and clinical presentation was classical. Cerebral infarction was more frequent in patients aged below 20 years and hemorrhage in those above 20 (p=0.11). The annual recurrence rate was 25%. Missed diagnosis rate by attending physician was 25%. The NIHSS and mRS showed high Stroke severity. Stroke management practices were insufficient and no patient received any form of Stroke prophylaxis. Conclusion: Stroke prevalence and presentation in sickle cell patients in Yaounde is similar to that observed in developed countries, but the wide management gap calls for rapid action. Our situation is ideal for the study of the natural history of Stroke in sickle cell disease.
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The Epidemiology of Stroke in sickle cell patients in Yaounde, Cameroon.
Journal of the neurological sciences, 2006Co-Authors: Alfred K Njamnshi, E N Mbong, Ambroise Wonkam, F L Sunjoh, Charles S Wiysonge, Roman Sztajzel, Dora Mbanya, P Ongolo-zogo, V-de-p Djientcheu, K Ngu BlackettAbstract:Stroke, a severe and recurrent but preventable complication of sickle cell disease (SCD), has not been well studied in Cameroon. To obtain baseline data towards the development of a national Stroke prevention programme in SCD, we studied a sample of sickle cell patients with the aim of determining Stroke prevalence, clinical presentation and management practices. Homozygous sickle cell patients in two centres in Yaounde were screened for Stroke, in a cross-sectional study. Stroke was diagnosed clinically and confirmed where possible with brain computerized tomography. The National Institutes of Health Stroke Score (NIHSS) and modified Rankin scale (mRS) were used to assess Stroke severity. Management practices were noted from patient charts. One hundred and twenty patients aged 7 months to 35 years (mean age 13.49+/-8.79 years) were included. Eight cases of Stroke (mean age 16.6+/-11.2 years) were identified, giving a Stroke prevalence of 6.67%. Cerebral infarction was thrice as common as cerebral hemorrhage and clinical presentation was classical. Cerebral infarction was more frequent in patients aged below 20 years and hemorrhage in those above 20 (p=0.11). The annual recurrence rate was 25%. Missed diagnosis rate by attending physician was 25%. The NIHSS and mRS showed high Stroke severity. Stroke management practices were insufficient and no patient received any form of Stroke prophylaxis. Stroke prevalence and presentation in sickle cell patients in Yaounde is similar to that observed in developed countries, but the wide management gap calls for rapid action. Our situation is ideal for the study of the natural history of Stroke in sickle cell disease.
F L Sunjoh - One of the best experts on this subject based on the ideXlab platform.
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the Epidemiology of Stroke in sickle cell patients in yaounde cameroon
Journal of the Neurological Sciences, 2006Co-Authors: Alfred K Njamnshi, E N Mbong, Ambroise Wonkam, Pierre Ongolozogo, Dep V Djientcheu, F L Sunjoh, Charles S Wiysonge, Roman Sztajzel, Dora Mbanya, Ngu K BlackettAbstract:Background and purpose: Stroke, a severe and recurrent but preventable complication of sickle cell disease (SCD), has not been well studied in Cameroon. To obtain baseline data towards the development of a national Stroke prevention programme in SCD, we studied a sample of sickle cell patients with the aim of determining Stroke prevalence, clinical presentation and management practices. Patients and methods: Homozygous sickle cell patients in two centres in Yaounde were screened for Stroke, in a cross-sectional study. Stroke was diagnosed clinically and confirmed where possible with brain computerized tomography. The National Institutes of Health Stroke Score (NIHSS) and modified Rankin scale (mRS) were used to assess Stroke severity. Management practices were noted from patient charts. Results: One hundred and twenty patients aged 7 months to 35 years (mean age 13.49±8.79 years) were included. Eight cases of Stroke (mean age 16.6±11.2 years) were identified, giving a Stroke prevalence of 6.67%. Cerebral infarction was thrice as common as cerebral hemorrhage and clinical presentation was classical. Cerebral infarction was more frequent in patients aged below 20 years and hemorrhage in those above 20 (p=0.11). The annual recurrence rate was 25%. Missed diagnosis rate by attending physician was 25%. The NIHSS and mRS showed high Stroke severity. Stroke management practices were insufficient and no patient received any form of Stroke prophylaxis. Conclusion: Stroke prevalence and presentation in sickle cell patients in Yaounde is similar to that observed in developed countries, but the wide management gap calls for rapid action. Our situation is ideal for the study of the natural history of Stroke in sickle cell disease.
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The Epidemiology of Stroke in sickle cell patients in Yaounde, Cameroon.
Journal of the neurological sciences, 2006Co-Authors: Alfred K Njamnshi, E N Mbong, Ambroise Wonkam, F L Sunjoh, Charles S Wiysonge, Roman Sztajzel, Dora Mbanya, P Ongolo-zogo, V-de-p Djientcheu, K Ngu BlackettAbstract:Stroke, a severe and recurrent but preventable complication of sickle cell disease (SCD), has not been well studied in Cameroon. To obtain baseline data towards the development of a national Stroke prevention programme in SCD, we studied a sample of sickle cell patients with the aim of determining Stroke prevalence, clinical presentation and management practices. Homozygous sickle cell patients in two centres in Yaounde were screened for Stroke, in a cross-sectional study. Stroke was diagnosed clinically and confirmed where possible with brain computerized tomography. The National Institutes of Health Stroke Score (NIHSS) and modified Rankin scale (mRS) were used to assess Stroke severity. Management practices were noted from patient charts. One hundred and twenty patients aged 7 months to 35 years (mean age 13.49+/-8.79 years) were included. Eight cases of Stroke (mean age 16.6+/-11.2 years) were identified, giving a Stroke prevalence of 6.67%. Cerebral infarction was thrice as common as cerebral hemorrhage and clinical presentation was classical. Cerebral infarction was more frequent in patients aged below 20 years and hemorrhage in those above 20 (p=0.11). The annual recurrence rate was 25%. Missed diagnosis rate by attending physician was 25%. The NIHSS and mRS showed high Stroke severity. Stroke management practices were insufficient and no patient received any form of Stroke prophylaxis. Stroke prevalence and presentation in sickle cell patients in Yaounde is similar to that observed in developed countries, but the wide management gap calls for rapid action. Our situation is ideal for the study of the natural history of Stroke in sickle cell disease.