The Experts below are selected from a list of 87 Experts worldwide ranked by ideXlab platform

Lawrence C. Newman - One of the best experts on this subject based on the ideXlab platform.

  • Chronic Daily Bilateral Headache Responsive to Indomethacin
    Headache, 1999
    Co-Authors: Seymour Solomon, Lawrence C. Newman
    Abstract:

    Indomethacin is known to be specifically effective for chronic Paroxysmal Hemicrania, Episodic Paroxysmal Hemicrania, and Hemicrania continua. Different forms of idiopathic stabbing headaches have also been responsive to indomethacin, but less consistently than the others. Two cases of indomethacin-responsive headache are reported. One patient presented with what appeared to be new-onset, chronic, daily, bilateral headache aggravated by coughing. Both the chronic daily headache and the exacerbations induced by coughing were suppressed with indomethacin therapy. The second patient experienced Hemicrania continua responsive to indomethacin, and the response persisted even when the headache evolved into bilateral continuous pain. There may be other idiopathic primary headache disorders that are peculiarly responsive to indomethacin. When any primary headache disorder does not respond to standard therapy, a brief therapeutic trial of indomethacin is warranted.

  • Episodic Paroxysmal Hemicrania: 3 New Cases and a Review of the Literature
    Headache, 1993
    Co-Authors: Lawrence C. Newman, Richard B. Lipton, Seymour Solomon
    Abstract:

    SYNOPSIS Episodic Paroxysmal Hemicrania (EPH) is a rare, benign disorder characterized by discrete bouts of Hemicranial headaches separated by periods of pain-free remissions. EPH is frequently mistaken for Episodic cluster headache because they have similar temporal profiles and clinical features. EPH is differentiated from cluster headaches by an increased frequency and a shorter duration of individual attacks. Establishing the diagnosis of EPH is important because of its unique response to treatment with indomethacin and not standard anti-cluster headache medications.

  • Episodic Paroxysmal Hemicrania: two new cases and a literature review.
    Neurology, 1992
    Co-Authors: Lawrence C. Newman, M. L. Gordon, Richard B. Lipton, Ronald M. Kanner, Scott D. Solomon
    Abstract:

    Episodic Paroxysmal Hemicrania (EPH) is a rare disorder characterized by discrete bouts of Hemicranial headache separated by headache-free remissions. Although EPH resembles Episodic cluster headache in the location and quality of pain as well as the pattern of associated autonomic features, it is distinguished by the greater frequency and shorter duration of individual headaches. Differentiation of these disorders is important because EPH almost invariably responds to treatment with indomethacin but not to standard cluster headache therapy.

  • Hemicrania continua attacks may alternate sides
    Headache, 1992
    Co-Authors: Lawrence C. Newman, Richard B. Lipton, R N Marjorie Russell, Seymour Solomon
    Abstract:

    Hemicrania continua (HC) is characterized by a continuous unilateral headache of moderate severity, occurring in 2 patterns; a continuous form in which headaches persist continuously without remission for years, and a remitting form, consisting of headache phases separated by periods of pain-free remission. The remitting form of HC must be distinguished from other cyclical headache disorders such as Episodic Paroxysmal Hemicrania and Episodic cluster headache. Characteristically, the headache of HC is unilateral and without sideshift. We now report a case of HC in which headaches alternate sides.

  • Chronic Paroxysmal Headache: Two Cases With Cerebrovascular Disease
    Headache, 1992
    Co-Authors: Lawrence C. Newman, Richard B. Lipton, Steven Herskovitz, Seymour Solomon
    Abstract:

    SYNOPSIS Paroxysmal headaches often occur in benign headache disorders such as Episodic cluster headache, chronic Paroxysmal Hemicrania (CPH) and Episodic Paroxysmal Hemicrania. We report 2 patients with Paroxysmal headaches occurring in association with cerebrovascular disease. The first patient had Paroxysmal headaches from an arteriovenous malformation which resolved following embolization. In the second patient, headache followed a cerebral infarction and responded to treatment with indomethacin. We suggest that vascular disease may cause Paroxysmal headaches resembling CPH. Patients with an atypical presentation of CPH warrant a neuroimaging procedure.

Francesco Pierelli - One of the best experts on this subject based on the ideXlab platform.

  • trait and frequency dependent dysfunctional habituation to trigeminal nociceptive stimulation in trigeminal autonomic cephalalgias
    The Journal of Pain, 2018
    Co-Authors: Armando Perrotta, Gianluca Coppola, Maria Grazia Anastasio, Anna Ambrosini, Mariano Serrao, Vincenzo Parisi, Giorgio Sandrini, Roberto De Icco, Maurizio Evangelista, Francesco Pierelli
    Abstract:

    Abstract We investigated whether the stimulation frequency (SF), the pain phases, and different diagnoses of trigeminal autonomic cephalalgias (TACs) may influence the habituation to pain. We studied the habituation of the nociceptive blink reflex R2 responses at different SFs (.05, .1, .2, .3, .5, and 1 Hz), in 28 Episodic cluster headache (ECH) patients, 16 during and 12 outside the bout; they were compared with 16 Episodic Paroxysmal Hemicrania (EPH) during the bout and 21 healthy subjects. We delivered 26 electrical stimuli and subdivided stimuli 2 to 26 in 5 blocks of 5 responses for each SF. Habituation values for each SF were expressed as the percentages of the mean area value of second through fifth blocks with respect to the first one. A significant lower mean percentage decrease of the R2 area across all blocks was found at .2 to 1 Hz SF during ECH, outside of the ECH, and EPH compared with healthy subjects. We showed a common frequency-dependent deficit of habituation of trigeminal nociceptive responses at higher SFs in ECH and EPH patients, independently from the disease phase. This abnormal temporal pattern of pain processing may suggest a trait-dependent dysfunction of some underlying pain-related subcortical structures, rather than a state-dependent functional abnormality due to the recurrence of the headache attacks during the active period. Perspective TACs showed a frequency-related defective habituation of nociceptive trigeminal responses at the higher SFs, irrespectively of the diagnosis and/or the disease phase. We showed that the clinical similarities in the different subtypes of TACs are in parallel with a trait-dependent dysfunction in pain processing.

  • Trait- and Frequency-Dependent Dysfunctional Habituation to Trigeminal Nociceptive Stimulation in Trigeminal Autonomic Cephalalgias
    'Elsevier BV', 2018
    Co-Authors: Armando Perrotta, Gianluca Coppola, Maria Grazia Anastasio, De Roberto, Anna Ambrosini, Mariano Serrao, Vincenzo Parisi, Evangelista Maurizio, Giorgio Sandrini, Francesco Pierelli
    Abstract:

    We investigated whether the stimulation frequency, the pain phases and different diagnoses of trigeminal autonomic cephalalgias (TACs) may influence the habituation to pain. We studied the habituation of the nociceptive blink reflex (nBR) R2 responses at different stimulation frequencies (SF, 0.05, 0.1, 0.2, 0.3, 0.5, 1Hz), in 28 Episodic cluster headache (ECH), 16 during (ECH-in) and 12 outside (ECH-out) the bout; they were compared with 16 Episodic Paroxysmal Hemicrania (EPH) during the bout and 21 healthy subjects (HS). We delivered 26 electrical stimuli and subdivided stimuli 2-26 in five blocks of five responses for each SF. Habituation values for each SF were expressed as the percentages of the mean area value of 2nd-5th block respect to the first one. A significant lower mean percentage decrease of the R2 area across all blocks was found at 0.2-1 Hz SF in ECH-in, ECH-out and EPH when compared to HS. We demonstrated a common frequency-dependent deficit of habituation of trigeminal nociceptive responses at higher SF in ECH and EPH patients, independently from the disease phase. This abnormal temporal pattern of pain processing may suggest a trait-dependent dysfunction of some underlying pain-related subcortical structures, rather than a state-dependent functional abnormality due to the recurrence of the headache attacks during the active period. PERSPECTIVE: Trigeminal autonomic cephalagias showed a frequency-related defective habituation of nociceptive trigeminal responses at the higher stimulation frequencies, irrespectively of the diagnosis and/or the disease phase. We demonstrated that the clinical similarities in the different subtypes of TACs are in parallel with a trait-dependent dysfunction in pain processing

Seymour Solomon - One of the best experts on this subject based on the ideXlab platform.

  • Chronic Daily Bilateral Headache Responsive to Indomethacin
    Headache, 1999
    Co-Authors: Seymour Solomon, Lawrence C. Newman
    Abstract:

    Indomethacin is known to be specifically effective for chronic Paroxysmal Hemicrania, Episodic Paroxysmal Hemicrania, and Hemicrania continua. Different forms of idiopathic stabbing headaches have also been responsive to indomethacin, but less consistently than the others. Two cases of indomethacin-responsive headache are reported. One patient presented with what appeared to be new-onset, chronic, daily, bilateral headache aggravated by coughing. Both the chronic daily headache and the exacerbations induced by coughing were suppressed with indomethacin therapy. The second patient experienced Hemicrania continua responsive to indomethacin, and the response persisted even when the headache evolved into bilateral continuous pain. There may be other idiopathic primary headache disorders that are peculiarly responsive to indomethacin. When any primary headache disorder does not respond to standard therapy, a brief therapeutic trial of indomethacin is warranted.

  • Episodic Paroxysmal Hemicrania: 3 New Cases and a Review of the Literature
    Headache, 1993
    Co-Authors: Lawrence C. Newman, Richard B. Lipton, Seymour Solomon
    Abstract:

    SYNOPSIS Episodic Paroxysmal Hemicrania (EPH) is a rare, benign disorder characterized by discrete bouts of Hemicranial headaches separated by periods of pain-free remissions. EPH is frequently mistaken for Episodic cluster headache because they have similar temporal profiles and clinical features. EPH is differentiated from cluster headaches by an increased frequency and a shorter duration of individual attacks. Establishing the diagnosis of EPH is important because of its unique response to treatment with indomethacin and not standard anti-cluster headache medications.

  • Hemicrania continua attacks may alternate sides
    Headache, 1992
    Co-Authors: Lawrence C. Newman, Richard B. Lipton, R N Marjorie Russell, Seymour Solomon
    Abstract:

    Hemicrania continua (HC) is characterized by a continuous unilateral headache of moderate severity, occurring in 2 patterns; a continuous form in which headaches persist continuously without remission for years, and a remitting form, consisting of headache phases separated by periods of pain-free remission. The remitting form of HC must be distinguished from other cyclical headache disorders such as Episodic Paroxysmal Hemicrania and Episodic cluster headache. Characteristically, the headache of HC is unilateral and without sideshift. We now report a case of HC in which headaches alternate sides.

  • Chronic Paroxysmal Headache: Two Cases With Cerebrovascular Disease
    Headache, 1992
    Co-Authors: Lawrence C. Newman, Richard B. Lipton, Steven Herskovitz, Seymour Solomon
    Abstract:

    SYNOPSIS Paroxysmal headaches often occur in benign headache disorders such as Episodic cluster headache, chronic Paroxysmal Hemicrania (CPH) and Episodic Paroxysmal Hemicrania. We report 2 patients with Paroxysmal headaches occurring in association with cerebrovascular disease. The first patient had Paroxysmal headaches from an arteriovenous malformation which resolved following embolization. In the second patient, headache followed a cerebral infarction and responded to treatment with indomethacin. We suggest that vascular disease may cause Paroxysmal headaches resembling CPH. Patients with an atypical presentation of CPH warrant a neuroimaging procedure.

Armando Perrotta - One of the best experts on this subject based on the ideXlab platform.

  • trait and frequency dependent dysfunctional habituation to trigeminal nociceptive stimulation in trigeminal autonomic cephalalgias
    The Journal of Pain, 2018
    Co-Authors: Armando Perrotta, Gianluca Coppola, Maria Grazia Anastasio, Anna Ambrosini, Mariano Serrao, Vincenzo Parisi, Giorgio Sandrini, Roberto De Icco, Maurizio Evangelista, Francesco Pierelli
    Abstract:

    Abstract We investigated whether the stimulation frequency (SF), the pain phases, and different diagnoses of trigeminal autonomic cephalalgias (TACs) may influence the habituation to pain. We studied the habituation of the nociceptive blink reflex R2 responses at different SFs (.05, .1, .2, .3, .5, and 1 Hz), in 28 Episodic cluster headache (ECH) patients, 16 during and 12 outside the bout; they were compared with 16 Episodic Paroxysmal Hemicrania (EPH) during the bout and 21 healthy subjects. We delivered 26 electrical stimuli and subdivided stimuli 2 to 26 in 5 blocks of 5 responses for each SF. Habituation values for each SF were expressed as the percentages of the mean area value of second through fifth blocks with respect to the first one. A significant lower mean percentage decrease of the R2 area across all blocks was found at .2 to 1 Hz SF during ECH, outside of the ECH, and EPH compared with healthy subjects. We showed a common frequency-dependent deficit of habituation of trigeminal nociceptive responses at higher SFs in ECH and EPH patients, independently from the disease phase. This abnormal temporal pattern of pain processing may suggest a trait-dependent dysfunction of some underlying pain-related subcortical structures, rather than a state-dependent functional abnormality due to the recurrence of the headache attacks during the active period. Perspective TACs showed a frequency-related defective habituation of nociceptive trigeminal responses at the higher SFs, irrespectively of the diagnosis and/or the disease phase. We showed that the clinical similarities in the different subtypes of TACs are in parallel with a trait-dependent dysfunction in pain processing.

  • Trait- and Frequency-Dependent Dysfunctional Habituation to Trigeminal Nociceptive Stimulation in Trigeminal Autonomic Cephalalgias
    'Elsevier BV', 2018
    Co-Authors: Armando Perrotta, Gianluca Coppola, Maria Grazia Anastasio, De Roberto, Anna Ambrosini, Mariano Serrao, Vincenzo Parisi, Evangelista Maurizio, Giorgio Sandrini, Francesco Pierelli
    Abstract:

    We investigated whether the stimulation frequency, the pain phases and different diagnoses of trigeminal autonomic cephalalgias (TACs) may influence the habituation to pain. We studied the habituation of the nociceptive blink reflex (nBR) R2 responses at different stimulation frequencies (SF, 0.05, 0.1, 0.2, 0.3, 0.5, 1Hz), in 28 Episodic cluster headache (ECH), 16 during (ECH-in) and 12 outside (ECH-out) the bout; they were compared with 16 Episodic Paroxysmal Hemicrania (EPH) during the bout and 21 healthy subjects (HS). We delivered 26 electrical stimuli and subdivided stimuli 2-26 in five blocks of five responses for each SF. Habituation values for each SF were expressed as the percentages of the mean area value of 2nd-5th block respect to the first one. A significant lower mean percentage decrease of the R2 area across all blocks was found at 0.2-1 Hz SF in ECH-in, ECH-out and EPH when compared to HS. We demonstrated a common frequency-dependent deficit of habituation of trigeminal nociceptive responses at higher SF in ECH and EPH patients, independently from the disease phase. This abnormal temporal pattern of pain processing may suggest a trait-dependent dysfunction of some underlying pain-related subcortical structures, rather than a state-dependent functional abnormality due to the recurrence of the headache attacks during the active period. PERSPECTIVE: Trigeminal autonomic cephalagias showed a frequency-related defective habituation of nociceptive trigeminal responses at the higher stimulation frequencies, irrespectively of the diagnosis and/or the disease phase. We demonstrated that the clinical similarities in the different subtypes of TACs are in parallel with a trait-dependent dysfunction in pain processing

Richard B. Lipton - One of the best experts on this subject based on the ideXlab platform.

  • Episodic Paroxysmal Hemicrania: 3 New Cases and a Review of the Literature
    Headache, 1993
    Co-Authors: Lawrence C. Newman, Richard B. Lipton, Seymour Solomon
    Abstract:

    SYNOPSIS Episodic Paroxysmal Hemicrania (EPH) is a rare, benign disorder characterized by discrete bouts of Hemicranial headaches separated by periods of pain-free remissions. EPH is frequently mistaken for Episodic cluster headache because they have similar temporal profiles and clinical features. EPH is differentiated from cluster headaches by an increased frequency and a shorter duration of individual attacks. Establishing the diagnosis of EPH is important because of its unique response to treatment with indomethacin and not standard anti-cluster headache medications.

  • Episodic Paroxysmal Hemicrania: two new cases and a literature review.
    Neurology, 1992
    Co-Authors: Lawrence C. Newman, M. L. Gordon, Richard B. Lipton, Ronald M. Kanner, Scott D. Solomon
    Abstract:

    Episodic Paroxysmal Hemicrania (EPH) is a rare disorder characterized by discrete bouts of Hemicranial headache separated by headache-free remissions. Although EPH resembles Episodic cluster headache in the location and quality of pain as well as the pattern of associated autonomic features, it is distinguished by the greater frequency and shorter duration of individual headaches. Differentiation of these disorders is important because EPH almost invariably responds to treatment with indomethacin but not to standard cluster headache therapy.

  • Hemicrania continua attacks may alternate sides
    Headache, 1992
    Co-Authors: Lawrence C. Newman, Richard B. Lipton, R N Marjorie Russell, Seymour Solomon
    Abstract:

    Hemicrania continua (HC) is characterized by a continuous unilateral headache of moderate severity, occurring in 2 patterns; a continuous form in which headaches persist continuously without remission for years, and a remitting form, consisting of headache phases separated by periods of pain-free remission. The remitting form of HC must be distinguished from other cyclical headache disorders such as Episodic Paroxysmal Hemicrania and Episodic cluster headache. Characteristically, the headache of HC is unilateral and without sideshift. We now report a case of HC in which headaches alternate sides.

  • Chronic Paroxysmal Headache: Two Cases With Cerebrovascular Disease
    Headache, 1992
    Co-Authors: Lawrence C. Newman, Richard B. Lipton, Steven Herskovitz, Seymour Solomon
    Abstract:

    SYNOPSIS Paroxysmal headaches often occur in benign headache disorders such as Episodic cluster headache, chronic Paroxysmal Hemicrania (CPH) and Episodic Paroxysmal Hemicrania. We report 2 patients with Paroxysmal headaches occurring in association with cerebrovascular disease. The first patient had Paroxysmal headaches from an arteriovenous malformation which resolved following embolization. In the second patient, headache followed a cerebral infarction and responded to treatment with indomethacin. We suggest that vascular disease may cause Paroxysmal headaches resembling CPH. Patients with an atypical presentation of CPH warrant a neuroimaging procedure.