The Experts below are selected from a list of 48 Experts worldwide ranked by ideXlab platform

Caroline Hahn - One of the best experts on this subject based on the ideXlab platform.

Catherine M. Mcgowan - One of the best experts on this subject based on the ideXlab platform.

  • Equine polysaccharide storage myopathy.
    Veterinary Record, 2005
    Co-Authors: Janet C. Patterson-kane, Josh Slater, Catherine M. Mcgowan
    Abstract:

    SIR, – We write in response to Caroline Hahn’s letter regarding Equine polysaccharide storage myopathy (EPSM) in horses in the UK ( VR , February 26, 2005, vol 156, p 292).We would disagree with the comment that EPSM is an uncommon cause of Equine Rhabdomyolysis syndrome in this country, both on

Sabry M Elbahr - One of the best experts on this subject based on the ideXlab platform.

  • selected biochemical indicators of Equine Rhabdomyolysis in arabian horses acute phase proteins and trace elements
    Journal of Equine Veterinary Science, 2014
    Co-Authors: Wael M Eldeeb, Sabry M Elbahr
    Abstract:

    Abstract Although creatine kinase (CK), aspartate transaminase (AST), cytokines, and oxidative stress parameters were shown to be useful biomarkers for diagnosis of Equine Rhabdomyolysis, additional biomarkers of the disease may be of interest to indicate prognosis of the disease. Therefore, the present study investigated acute phase proteins and trace elements as additional biomarkers of ER. Sixty male horses (4-6 years old) of 2 equal groups were used. Horses of the first group were clinically healthy and served as a control group, whereas horses of the second group were ER-diseased animals. Harvested sera were used for estimation of the activities of CK, AST, lactate dehydrogenase (LDH), serum amyloid A (SAA), haptoglobin (Hp), ceruloplasmin (Cp), copper, iron, and zinc, whereas plasma samples were used for determination of fibrinogen. The present findings revealed a significant ( P ≤ .05) increase in values of CK, AST, and LDH in diseased horses compared to those in control values. In addition, a significant ( P ≤ .05) increase in SAA (162.6 ± 5.32 mg/L), Hp (3.6 ± 0.54 g/L), Cp (39.32 ± 2.31 mg/L), and copper (28.36 ± 1.23 μmol/L) along with a significant ( P ≤ .05) reduction in levels of iron (9.32 ± 0.23 μmol/L) and zinc (8.65 ± 1.02 μmol/L) was recorded in diseased horses compare to that in controls (11.3 ± 2.2 mg/L, 0.8 ± 0.2 g/L, 24.23 ± 1.32 mg/L, 18.41 ± 1.03 μmol/L, and 14.2 ± 0.42 μmol/L, respectively). In conclusion, SAA, Hp, Cp, copper, and zinc were useful prognostic biomarkers for the diagnosis of ER in Arabian horses.

Andre Terzic - One of the best experts on this subject based on the ideXlab platform.

  • elevated myoplasmic calcium in exercise induced Equine Rhabdomyolysis
    Pflügers Archiv: European Journal of Physiology, 1995
    Co-Authors: Jose R Lopez, Nancy Linares, G Cordovez, Andre Terzic
    Abstract:

    Exertional Rhabdomyolysis is a myopathy of unknown pathophysiology. We measured intracellular resting calcium concentration ([Ca2+]i) by means of Ca2+-selective microelectrodes in intercostal muscle fibers from horses suffering from Rhabdomyolysis, and from horses with no evidence of neuromuscular disorder. [Ca2+]i was several-fold higher in muscle fibers from horses suffering from Rhabdomyolysis when compared to controls. Treatment of rhabdomyolytic horses with dantrolene, an agent that prevents Ca2+ release from the sarcoplasmic reticulum, reduced [Ca2+]i toward control values, and accelerated the recovery from this myopathy. These results indicate that an acute episode of Rhabdomyolysis is associated with elevation in [Ca2+]i in skeletal muscles, and that dantrolene might be of benefit in treating this disease.

Janet C. Patterson-kane - One of the best experts on this subject based on the ideXlab platform.

  • Equine polysaccharide storage myopathy.
    Veterinary Record, 2005
    Co-Authors: Janet C. Patterson-kane, Josh Slater, Catherine M. Mcgowan
    Abstract:

    SIR, – We write in response to Caroline Hahn’s letter regarding Equine polysaccharide storage myopathy (EPSM) in horses in the UK ( VR , February 26, 2005, vol 156, p 292).We would disagree with the comment that EPSM is an uncommon cause of Equine Rhabdomyolysis syndrome in this country, both on