Rhabdomyolysis

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Lyell K Jones - One of the best experts on this subject based on the ideXlab platform.

  • natural history of exertional Rhabdomyolysis a population based analysis
    Muscle & Nerve, 2010
    Co-Authors: Joshua P Alpers, Lyell K Jones
    Abstract:

    Exertional Rhabdomyolysis is a potentially catastrophic syndrome with an incidence and rate of recurrence that are unknown. In this study patients with Rhabdomyolysis were identified retrospectively from the Wilford Hall Medical Center records. A population-based analysis was performed on exertional Rhabdomyolysis patients enrolled in basic military training. A retrospective cohort was analyzed for rate and risks of recurrence. Of 177 Rhabdomyolysis patients, 63 were exertional in mechanism. The rate of renal failure was lower in exertional Rhabdomyolysis patients (odds ratio 0.45, 95% confidence interval 0.22–0.95, P = 0.04). There were 44 cases of exertional Rhabdomyolysis from a population of 198,399 total military trainees over the study period, or 22.2 cases per 100,000 per year. A cohort of 22 exertional Rhabdomyolysis patients was followed for a mean of 31.2 months, with only 1 recurrence (recurrence risk of 0.08% per person per year). Exertional Rhabdomyolysis is associated with lower rates of complications than other causes of Rhabdomyolysis. Among young, physically active patients, the incidence of exertional Rhabdomyolysis is low, as is the risk of recurrence. Muscle Nerve, 2010

  • natural history of exertional Rhabdomyolysis a population based analysis
    Muscle & Nerve, 2010
    Co-Authors: Joshua P Alpers, Lyell K Jones
    Abstract:

    Exertional Rhabdomyolysis is a potentially catastrophic syndrome with an incidence and rate of recurrence that are unknown. In this study patients with Rhabdomyolysis were identified retrospectively from the Wilford Hall Medical Center records. A population-based analysis was performed on exertional Rhabdomyolysis patients enrolled in basic military training. A retrospective cohort was analyzed for rate and risks of recurrence. Of 177 Rhabdomyolysis patients, 63 were exertional in mechanism. The rate of renal failure was lower in exertional Rhabdomyolysis patients (odds ratio 0.45, 95% confidence interval 0.22-0.95, P = 0.04). There were 44 cases of exertional Rhabdomyolysis from a population of 198,399 total military trainees over the study period, or 22.2 cases per 100,000 per year. A cohort of 22 exertional Rhabdomyolysis patients was followed for a mean of 31.2 months, with only 1 recurrence (recurrence risk of 0.08% per person per year). Exertional Rhabdomyolysis is associated with lower rates of complications than other causes of Rhabdomyolysis. Among young, physically active patients, the incidence of exertional Rhabdomyolysis is low, as is the risk of recurrence.

Joshua P Alpers - One of the best experts on this subject based on the ideXlab platform.

  • natural history of exertional Rhabdomyolysis a population based analysis
    Muscle & Nerve, 2010
    Co-Authors: Joshua P Alpers, Lyell K Jones
    Abstract:

    Exertional Rhabdomyolysis is a potentially catastrophic syndrome with an incidence and rate of recurrence that are unknown. In this study patients with Rhabdomyolysis were identified retrospectively from the Wilford Hall Medical Center records. A population-based analysis was performed on exertional Rhabdomyolysis patients enrolled in basic military training. A retrospective cohort was analyzed for rate and risks of recurrence. Of 177 Rhabdomyolysis patients, 63 were exertional in mechanism. The rate of renal failure was lower in exertional Rhabdomyolysis patients (odds ratio 0.45, 95% confidence interval 0.22–0.95, P = 0.04). There were 44 cases of exertional Rhabdomyolysis from a population of 198,399 total military trainees over the study period, or 22.2 cases per 100,000 per year. A cohort of 22 exertional Rhabdomyolysis patients was followed for a mean of 31.2 months, with only 1 recurrence (recurrence risk of 0.08% per person per year). Exertional Rhabdomyolysis is associated with lower rates of complications than other causes of Rhabdomyolysis. Among young, physically active patients, the incidence of exertional Rhabdomyolysis is low, as is the risk of recurrence. Muscle Nerve, 2010

  • natural history of exertional Rhabdomyolysis a population based analysis
    Muscle & Nerve, 2010
    Co-Authors: Joshua P Alpers, Lyell K Jones
    Abstract:

    Exertional Rhabdomyolysis is a potentially catastrophic syndrome with an incidence and rate of recurrence that are unknown. In this study patients with Rhabdomyolysis were identified retrospectively from the Wilford Hall Medical Center records. A population-based analysis was performed on exertional Rhabdomyolysis patients enrolled in basic military training. A retrospective cohort was analyzed for rate and risks of recurrence. Of 177 Rhabdomyolysis patients, 63 were exertional in mechanism. The rate of renal failure was lower in exertional Rhabdomyolysis patients (odds ratio 0.45, 95% confidence interval 0.22-0.95, P = 0.04). There were 44 cases of exertional Rhabdomyolysis from a population of 198,399 total military trainees over the study period, or 22.2 cases per 100,000 per year. A cohort of 22 exertional Rhabdomyolysis patients was followed for a mean of 31.2 months, with only 1 recurrence (recurrence risk of 0.08% per person per year). Exertional Rhabdomyolysis is associated with lower rates of complications than other causes of Rhabdomyolysis. Among young, physically active patients, the incidence of exertional Rhabdomyolysis is low, as is the risk of recurrence.

Matthew Shaines - One of the best experts on this subject based on the ideXlab platform.

  • case report exertional Rhabdomyolysis in a spin class participant with sickle cell trait
    F1000Research, 2018
    Co-Authors: Teresa Longo, Matthew Shaines
    Abstract:

    Exertional Rhabdomyolysis is more common in sickle trait due to a predisposition to dehydration and inability to concentrate the urine. Spinning, an indoor cycling workout, has been associated with exertional Rhabdomyolysis in recent reports. A consequence of Rhabdomyolysis is acute kidney injury, which may be expected to be more common in patients with sickle trait. We report a case of spinning induced Rhabdomyolysis in a woman with sickle trait that did not result in renal injury. “Spin rhabdo” is thought to be more severe than other causes of exertional Rhabdomyolysis and is associated with higher creatine kinase levels than other causes of exertional Rhabdomyolysis. Therefore, individuals with known sickle trait should consider visiting their physician prior to participation in spin classes for the first time. We might also consider voluntary screening for sickle trait in at risk populations prior to enrolling in spin classes given that many patients are unaware of their sickle trait status.

  • Case Report: Exertional Rhabdomyolysis in a spin class participant with sickle cell trait
    F1000Research, 2018
    Co-Authors: Teresa Longo, Matthew Shaines
    Abstract:

    Exertional Rhabdomyolysis is more common in sickle trait due to a predisposition to dehydration and inability to concentrate the urine. Spinning, an indoor cycling workout, has been associated with exertional Rhabdomyolysis in recent reports. A consequence of Rhabdomyolysis is acute kidney injury, which may be expected to be more common in patients with sickle trait. We report a case of spinning induced Rhabdomyolysis in a woman with sickle trait that did not result in renal injury. “Spin rhabdo” is thought to be more severe than other causes of exertional Rhabdomyolysis and is associated with higher creatine kinase levels than other causes of exertional Rhabdomyolysis. Therefore, individuals with known sickle trait should visit their physician prior to participation in spin classes for the first time. We might also consider voluntary screening for sickle trait in at risk populations prior to enrolling in spin classes given that many patients are unaware of their sickle trait status.

Mark A Tarnopolsky - One of the best experts on this subject based on the ideXlab platform.

  • Perspectives on Exertional Rhabdomyolysis
    Sports Medicine, 2017
    Co-Authors: Eric S. Rawson, Priscilla M. Clarkson, Mark A Tarnopolsky
    Abstract:

    Exertional (exercise-induced) Rhabdomyolysis is a potentially life threatening condition that has been the subject of research, intense discussion, and media attention. The causes of Rhabdomyolysis are numerous and can include direct muscle injury, unaccustomed exercise, ischemia, extreme temperatures, electrolyte abnormalities, endocrinologic conditions, genetic disorders, autoimmune disorders, infections, drugs, toxins, and venoms. The objective of this article is to review the literature on exertional Rhabdomyolysis, identify precipitating factors, and examine the role of the dietary supplement creatine monohydrate. PubMed and SPORTDiscus databases were searched using the terms Rhabdomyolysis, muscle damage, creatine, creatine supplementation, creatine monohydrate, and phosphocreatine. Additionally, the references of papers identified through this search were examined for relevant studies. A meta-analysis was not performed. Although the prevalence of Rhabdomyolysis is low, instances still occur where exercise is improperly prescribed or used as punishment, or incomplete medical history is taken, and exertional Rhabdomyolysis occurs. Creatine monohydrate does not appear to be a precipitating factor for exertional Rhabdomyolysis. Healthcare professionals should be able to recognize the basic signs of exertional Rhabdomyolysis so prompt treatment can be administered. For the risk of Rhabdomyolysis to remain low, exercise testing and prescription must be properly conducted based on professional standards.

Teresa Longo - One of the best experts on this subject based on the ideXlab platform.

  • case report exertional Rhabdomyolysis in a spin class participant with sickle cell trait
    F1000Research, 2018
    Co-Authors: Teresa Longo, Matthew Shaines
    Abstract:

    Exertional Rhabdomyolysis is more common in sickle trait due to a predisposition to dehydration and inability to concentrate the urine. Spinning, an indoor cycling workout, has been associated with exertional Rhabdomyolysis in recent reports. A consequence of Rhabdomyolysis is acute kidney injury, which may be expected to be more common in patients with sickle trait. We report a case of spinning induced Rhabdomyolysis in a woman with sickle trait that did not result in renal injury. “Spin rhabdo” is thought to be more severe than other causes of exertional Rhabdomyolysis and is associated with higher creatine kinase levels than other causes of exertional Rhabdomyolysis. Therefore, individuals with known sickle trait should consider visiting their physician prior to participation in spin classes for the first time. We might also consider voluntary screening for sickle trait in at risk populations prior to enrolling in spin classes given that many patients are unaware of their sickle trait status.

  • Case Report: Exertional Rhabdomyolysis in a spin class participant with sickle cell trait
    F1000Research, 2018
    Co-Authors: Teresa Longo, Matthew Shaines
    Abstract:

    Exertional Rhabdomyolysis is more common in sickle trait due to a predisposition to dehydration and inability to concentrate the urine. Spinning, an indoor cycling workout, has been associated with exertional Rhabdomyolysis in recent reports. A consequence of Rhabdomyolysis is acute kidney injury, which may be expected to be more common in patients with sickle trait. We report a case of spinning induced Rhabdomyolysis in a woman with sickle trait that did not result in renal injury. “Spin rhabdo” is thought to be more severe than other causes of exertional Rhabdomyolysis and is associated with higher creatine kinase levels than other causes of exertional Rhabdomyolysis. Therefore, individuals with known sickle trait should visit their physician prior to participation in spin classes for the first time. We might also consider voluntary screening for sickle trait in at risk populations prior to enrolling in spin classes given that many patients are unaware of their sickle trait status.