The Experts below are selected from a list of 273 Experts worldwide ranked by ideXlab platform
Yoshikazu Kinoshita - One of the best experts on this subject based on the ideXlab platform.
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Does magnifying endoscopy improve the diagnosis of erosive Esophagitis?
Journal of gastroenterology and hepatology, 2008Co-Authors: Yuji Amano, Haruhiro Yamashita, Kenji Koshino, Tadayuki Ohshima, Hiroto Miwa, Ryuichi Iwakiri, Kazuma Fujimoto, Noriaki Manabe, Ken Haruma, Yoshikazu KinoshitaAbstract:Low-grade erosive Esophagitis (i.e. Los Angeles grade A) is the most predominant type of Esophagitis in Japan. It is unclear whether all the mucosal breaks detected by conventional endoscopy are indicative of esophageal mucosal erosion. Hospital-based, cross-sectional, cross-over, observational study was assigned to investigate the value of magnifying endoscopy for diagnosis of erosive Esophagitis. From August to December 2006, 178 consecutive patients with upper gastrointestinal symptoms were enrolled at three university hospitals and one national medical center in western Japan. Before endoscopy, all participants were requested to answer questionnaires concerning their symptoms. Experienced endoscopists performed an endoscopic diagnosis of each patient first with a conventional standard view and then with a magnifying view. Endoscopic diagnostic concordance between conventional and magnifying endoscopic view for erosive Esophagitis was calculated. Relationship between a variety of symptoms and erosive Esophagitis was also evaluated. Erosive Esophagitis was identified using conventional and magnifying endoscopy in 14.6% and 17.4% of patients, respectively. Eleven false-negative and six false-positive diagnoses using conventional endoscopy occurred among the 178 enrolled patients. The weighted kappa value of diagnostic concordance for erosive Esophagitis between the two endoscopic views was 0.76. The prevalence of erosive Esophagitis in patients with reflux-, dysmotility-, and ulcer-like symptoms was 20.7%, 24.1%, and 15.2%, respectively. Magnifying endoscopy did not significantly improve the diagnostic sensitivity of erosive Esophagitis over non-magnifying, conventional endoscopy. Erosive Esophagitis was frequently identified in patients that did not have reflux symptoms.
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Does magnifying endoscopy improve the diagnosis of erosive Esophagitis
Journal of Gastroenterology and Hepatology, 2008Co-Authors: Yuji Amano, Haruhiro Yamashita, Kenji Koshino, Tadayuki Ohshima, Hiroto Miwa, Ryuichi Iwakiri, Kazuma Fujimoto, Noriaki Manabe, Ken Haruma, Yoshikazu KinoshitaAbstract:Background and Aims: Low-grade erosive Esophagitis (i.e. Los Angeles grade A) is the most predominant type of Esophagitis in Japan. It is unclear whether all the mucosal breaks detected by conventional endoscopy are indicative of esophageal mucosal erosion. Hospital-based, cross-sectional, cross-over, observational study was assigned to investigate the value of magnifying endoscopy for diagnosis of erosive Esophagitis. Methods: From August to December 2006, 178 consecutive patients with upper gastrointestinal symptoms were enrolled at three university hospitals and one national medical center in western Japan. Before endoscopy, all participants were requested to answer questionnaires concerning their symptoms. Experienced endoscopists performed an endoscopic diagnosis of each patient first with a conventional standard view and then with a magnifying view. Endoscopic diagnostic concordance between conventional and magnifying endoscopic view for erosive Esophagitis was calculated. Relationship between a variety of symptoms and erosive Esophagitis was also evaluated. Results: Erosive Esophagitis was identified using conventional and magnifying endoscopy in 14.6% and 17.4% of patients, respectively. Eleven false-negative and six false-positive diagnoses using conventional endoscopy occurred among the 178 enrolled patients. The weighted kappa value of diagnostic concordance for erosive Esophagitis between the two endoscopic views was 0.76. The prevalence of erosive Esophagitis in patients with reflux-, dysmotility-, and ulcer-like symptoms was 20.7%, 24.1%, and 15.2%, respectively. Conclusions: Magnifying endoscopy did not significantly improve the diagnostic sensitivity of erosive Esophagitis over non-magnifying, conventional endoscopy. Erosive Esophagitis was frequently identified in patients that did not have reflux symptoms.
Kazuma Fujimoto - One of the best experts on this subject based on the ideXlab platform.
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Does magnifying endoscopy improve the diagnosis of erosive Esophagitis?
Journal of gastroenterology and hepatology, 2008Co-Authors: Yuji Amano, Haruhiro Yamashita, Kenji Koshino, Tadayuki Ohshima, Hiroto Miwa, Ryuichi Iwakiri, Kazuma Fujimoto, Noriaki Manabe, Ken Haruma, Yoshikazu KinoshitaAbstract:Low-grade erosive Esophagitis (i.e. Los Angeles grade A) is the most predominant type of Esophagitis in Japan. It is unclear whether all the mucosal breaks detected by conventional endoscopy are indicative of esophageal mucosal erosion. Hospital-based, cross-sectional, cross-over, observational study was assigned to investigate the value of magnifying endoscopy for diagnosis of erosive Esophagitis. From August to December 2006, 178 consecutive patients with upper gastrointestinal symptoms were enrolled at three university hospitals and one national medical center in western Japan. Before endoscopy, all participants were requested to answer questionnaires concerning their symptoms. Experienced endoscopists performed an endoscopic diagnosis of each patient first with a conventional standard view and then with a magnifying view. Endoscopic diagnostic concordance between conventional and magnifying endoscopic view for erosive Esophagitis was calculated. Relationship between a variety of symptoms and erosive Esophagitis was also evaluated. Erosive Esophagitis was identified using conventional and magnifying endoscopy in 14.6% and 17.4% of patients, respectively. Eleven false-negative and six false-positive diagnoses using conventional endoscopy occurred among the 178 enrolled patients. The weighted kappa value of diagnostic concordance for erosive Esophagitis between the two endoscopic views was 0.76. The prevalence of erosive Esophagitis in patients with reflux-, dysmotility-, and ulcer-like symptoms was 20.7%, 24.1%, and 15.2%, respectively. Magnifying endoscopy did not significantly improve the diagnostic sensitivity of erosive Esophagitis over non-magnifying, conventional endoscopy. Erosive Esophagitis was frequently identified in patients that did not have reflux symptoms.
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Does magnifying endoscopy improve the diagnosis of erosive Esophagitis
Journal of Gastroenterology and Hepatology, 2008Co-Authors: Yuji Amano, Haruhiro Yamashita, Kenji Koshino, Tadayuki Ohshima, Hiroto Miwa, Ryuichi Iwakiri, Kazuma Fujimoto, Noriaki Manabe, Ken Haruma, Yoshikazu KinoshitaAbstract:Background and Aims: Low-grade erosive Esophagitis (i.e. Los Angeles grade A) is the most predominant type of Esophagitis in Japan. It is unclear whether all the mucosal breaks detected by conventional endoscopy are indicative of esophageal mucosal erosion. Hospital-based, cross-sectional, cross-over, observational study was assigned to investigate the value of magnifying endoscopy for diagnosis of erosive Esophagitis. Methods: From August to December 2006, 178 consecutive patients with upper gastrointestinal symptoms were enrolled at three university hospitals and one national medical center in western Japan. Before endoscopy, all participants were requested to answer questionnaires concerning their symptoms. Experienced endoscopists performed an endoscopic diagnosis of each patient first with a conventional standard view and then with a magnifying view. Endoscopic diagnostic concordance between conventional and magnifying endoscopic view for erosive Esophagitis was calculated. Relationship between a variety of symptoms and erosive Esophagitis was also evaluated. Results: Erosive Esophagitis was identified using conventional and magnifying endoscopy in 14.6% and 17.4% of patients, respectively. Eleven false-negative and six false-positive diagnoses using conventional endoscopy occurred among the 178 enrolled patients. The weighted kappa value of diagnostic concordance for erosive Esophagitis between the two endoscopic views was 0.76. The prevalence of erosive Esophagitis in patients with reflux-, dysmotility-, and ulcer-like symptoms was 20.7%, 24.1%, and 15.2%, respectively. Conclusions: Magnifying endoscopy did not significantly improve the diagnostic sensitivity of erosive Esophagitis over non-magnifying, conventional endoscopy. Erosive Esophagitis was frequently identified in patients that did not have reflux symptoms.
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Clinical Symptoms in Endoscopic Reflux Esophagitis: Evaluation in 8031 Adult Subjects
Digestive Diseases and Sciences, 2003Co-Authors: Kazuyo Okamoto, Ryuichi Iwakiri, Mitsuru Mori, Megumi Hara, Kayoko Oda, Akiko Danjo, Akifumi Ootani, Hiroyuki Sakata, Kazuma FujimotoAbstract:This study aimed to evaluate the correlation between symptoms and endoscopic findings in reflux Esophagitis. Subjects, 8031 persons without medication for gastrointestinal disease, were briefly asked about the presence of heartburn, dysphagia, odynophagia, and acid regurgitation by associated medical staff before endoscopy for assessment of Esophagitis utilizing the Los Angeles Classification. Endoscopically, 1199 (14.9%) were classified as positive reflux Esophagitis, and 2223 (27.7%) had heartburn, 1522 (19.0%) had dysphagia, 493 (6.1%) had odynophagia, and 1466 (18.3%) had acid regurgitation. Multivariate analysis indicated that the symptom most related to Esophagitis was heartburn (odds ratio: 2.46), although ∼40% of subjects with grade C or D did not complain of heartburn. Regarding the other symptoms, less than 30% subjects with severe Esophagitis complained of the symptoms and the odds ratio was ∼1. These results indicate that endoscopic Esophagitis was not equivalent to any reflux symptoms from which subjects suffered in their daily lives.
Ryuichi Iwakiri - One of the best experts on this subject based on the ideXlab platform.
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Does magnifying endoscopy improve the diagnosis of erosive Esophagitis?
Journal of gastroenterology and hepatology, 2008Co-Authors: Yuji Amano, Haruhiro Yamashita, Kenji Koshino, Tadayuki Ohshima, Hiroto Miwa, Ryuichi Iwakiri, Kazuma Fujimoto, Noriaki Manabe, Ken Haruma, Yoshikazu KinoshitaAbstract:Low-grade erosive Esophagitis (i.e. Los Angeles grade A) is the most predominant type of Esophagitis in Japan. It is unclear whether all the mucosal breaks detected by conventional endoscopy are indicative of esophageal mucosal erosion. Hospital-based, cross-sectional, cross-over, observational study was assigned to investigate the value of magnifying endoscopy for diagnosis of erosive Esophagitis. From August to December 2006, 178 consecutive patients with upper gastrointestinal symptoms were enrolled at three university hospitals and one national medical center in western Japan. Before endoscopy, all participants were requested to answer questionnaires concerning their symptoms. Experienced endoscopists performed an endoscopic diagnosis of each patient first with a conventional standard view and then with a magnifying view. Endoscopic diagnostic concordance between conventional and magnifying endoscopic view for erosive Esophagitis was calculated. Relationship between a variety of symptoms and erosive Esophagitis was also evaluated. Erosive Esophagitis was identified using conventional and magnifying endoscopy in 14.6% and 17.4% of patients, respectively. Eleven false-negative and six false-positive diagnoses using conventional endoscopy occurred among the 178 enrolled patients. The weighted kappa value of diagnostic concordance for erosive Esophagitis between the two endoscopic views was 0.76. The prevalence of erosive Esophagitis in patients with reflux-, dysmotility-, and ulcer-like symptoms was 20.7%, 24.1%, and 15.2%, respectively. Magnifying endoscopy did not significantly improve the diagnostic sensitivity of erosive Esophagitis over non-magnifying, conventional endoscopy. Erosive Esophagitis was frequently identified in patients that did not have reflux symptoms.
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Does magnifying endoscopy improve the diagnosis of erosive Esophagitis
Journal of Gastroenterology and Hepatology, 2008Co-Authors: Yuji Amano, Haruhiro Yamashita, Kenji Koshino, Tadayuki Ohshima, Hiroto Miwa, Ryuichi Iwakiri, Kazuma Fujimoto, Noriaki Manabe, Ken Haruma, Yoshikazu KinoshitaAbstract:Background and Aims: Low-grade erosive Esophagitis (i.e. Los Angeles grade A) is the most predominant type of Esophagitis in Japan. It is unclear whether all the mucosal breaks detected by conventional endoscopy are indicative of esophageal mucosal erosion. Hospital-based, cross-sectional, cross-over, observational study was assigned to investigate the value of magnifying endoscopy for diagnosis of erosive Esophagitis. Methods: From August to December 2006, 178 consecutive patients with upper gastrointestinal symptoms were enrolled at three university hospitals and one national medical center in western Japan. Before endoscopy, all participants were requested to answer questionnaires concerning their symptoms. Experienced endoscopists performed an endoscopic diagnosis of each patient first with a conventional standard view and then with a magnifying view. Endoscopic diagnostic concordance between conventional and magnifying endoscopic view for erosive Esophagitis was calculated. Relationship between a variety of symptoms and erosive Esophagitis was also evaluated. Results: Erosive Esophagitis was identified using conventional and magnifying endoscopy in 14.6% and 17.4% of patients, respectively. Eleven false-negative and six false-positive diagnoses using conventional endoscopy occurred among the 178 enrolled patients. The weighted kappa value of diagnostic concordance for erosive Esophagitis between the two endoscopic views was 0.76. The prevalence of erosive Esophagitis in patients with reflux-, dysmotility-, and ulcer-like symptoms was 20.7%, 24.1%, and 15.2%, respectively. Conclusions: Magnifying endoscopy did not significantly improve the diagnostic sensitivity of erosive Esophagitis over non-magnifying, conventional endoscopy. Erosive Esophagitis was frequently identified in patients that did not have reflux symptoms.
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Clinical Symptoms in Endoscopic Reflux Esophagitis: Evaluation in 8031 Adult Subjects
Digestive Diseases and Sciences, 2003Co-Authors: Kazuyo Okamoto, Ryuichi Iwakiri, Mitsuru Mori, Megumi Hara, Kayoko Oda, Akiko Danjo, Akifumi Ootani, Hiroyuki Sakata, Kazuma FujimotoAbstract:This study aimed to evaluate the correlation between symptoms and endoscopic findings in reflux Esophagitis. Subjects, 8031 persons without medication for gastrointestinal disease, were briefly asked about the presence of heartburn, dysphagia, odynophagia, and acid regurgitation by associated medical staff before endoscopy for assessment of Esophagitis utilizing the Los Angeles Classification. Endoscopically, 1199 (14.9%) were classified as positive reflux Esophagitis, and 2223 (27.7%) had heartburn, 1522 (19.0%) had dysphagia, 493 (6.1%) had odynophagia, and 1466 (18.3%) had acid regurgitation. Multivariate analysis indicated that the symptom most related to Esophagitis was heartburn (odds ratio: 2.46), although ∼40% of subjects with grade C or D did not complain of heartburn. Regarding the other symptoms, less than 30% subjects with severe Esophagitis complained of the symptoms and the odds ratio was ∼1. These results indicate that endoscopic Esophagitis was not equivalent to any reflux symptoms from which subjects suffered in their daily lives.
Yuji Amano - One of the best experts on this subject based on the ideXlab platform.
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Does magnifying endoscopy improve the diagnosis of erosive Esophagitis?
Journal of gastroenterology and hepatology, 2008Co-Authors: Yuji Amano, Haruhiro Yamashita, Kenji Koshino, Tadayuki Ohshima, Hiroto Miwa, Ryuichi Iwakiri, Kazuma Fujimoto, Noriaki Manabe, Ken Haruma, Yoshikazu KinoshitaAbstract:Low-grade erosive Esophagitis (i.e. Los Angeles grade A) is the most predominant type of Esophagitis in Japan. It is unclear whether all the mucosal breaks detected by conventional endoscopy are indicative of esophageal mucosal erosion. Hospital-based, cross-sectional, cross-over, observational study was assigned to investigate the value of magnifying endoscopy for diagnosis of erosive Esophagitis. From August to December 2006, 178 consecutive patients with upper gastrointestinal symptoms were enrolled at three university hospitals and one national medical center in western Japan. Before endoscopy, all participants were requested to answer questionnaires concerning their symptoms. Experienced endoscopists performed an endoscopic diagnosis of each patient first with a conventional standard view and then with a magnifying view. Endoscopic diagnostic concordance between conventional and magnifying endoscopic view for erosive Esophagitis was calculated. Relationship between a variety of symptoms and erosive Esophagitis was also evaluated. Erosive Esophagitis was identified using conventional and magnifying endoscopy in 14.6% and 17.4% of patients, respectively. Eleven false-negative and six false-positive diagnoses using conventional endoscopy occurred among the 178 enrolled patients. The weighted kappa value of diagnostic concordance for erosive Esophagitis between the two endoscopic views was 0.76. The prevalence of erosive Esophagitis in patients with reflux-, dysmotility-, and ulcer-like symptoms was 20.7%, 24.1%, and 15.2%, respectively. Magnifying endoscopy did not significantly improve the diagnostic sensitivity of erosive Esophagitis over non-magnifying, conventional endoscopy. Erosive Esophagitis was frequently identified in patients that did not have reflux symptoms.
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Does magnifying endoscopy improve the diagnosis of erosive Esophagitis
Journal of Gastroenterology and Hepatology, 2008Co-Authors: Yuji Amano, Haruhiro Yamashita, Kenji Koshino, Tadayuki Ohshima, Hiroto Miwa, Ryuichi Iwakiri, Kazuma Fujimoto, Noriaki Manabe, Ken Haruma, Yoshikazu KinoshitaAbstract:Background and Aims: Low-grade erosive Esophagitis (i.e. Los Angeles grade A) is the most predominant type of Esophagitis in Japan. It is unclear whether all the mucosal breaks detected by conventional endoscopy are indicative of esophageal mucosal erosion. Hospital-based, cross-sectional, cross-over, observational study was assigned to investigate the value of magnifying endoscopy for diagnosis of erosive Esophagitis. Methods: From August to December 2006, 178 consecutive patients with upper gastrointestinal symptoms were enrolled at three university hospitals and one national medical center in western Japan. Before endoscopy, all participants were requested to answer questionnaires concerning their symptoms. Experienced endoscopists performed an endoscopic diagnosis of each patient first with a conventional standard view and then with a magnifying view. Endoscopic diagnostic concordance between conventional and magnifying endoscopic view for erosive Esophagitis was calculated. Relationship between a variety of symptoms and erosive Esophagitis was also evaluated. Results: Erosive Esophagitis was identified using conventional and magnifying endoscopy in 14.6% and 17.4% of patients, respectively. Eleven false-negative and six false-positive diagnoses using conventional endoscopy occurred among the 178 enrolled patients. The weighted kappa value of diagnostic concordance for erosive Esophagitis between the two endoscopic views was 0.76. The prevalence of erosive Esophagitis in patients with reflux-, dysmotility-, and ulcer-like symptoms was 20.7%, 24.1%, and 15.2%, respectively. Conclusions: Magnifying endoscopy did not significantly improve the diagnostic sensitivity of erosive Esophagitis over non-magnifying, conventional endoscopy. Erosive Esophagitis was frequently identified in patients that did not have reflux symptoms.
Mariko Suchi - One of the best experts on this subject based on the ideXlab platform.
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Herpes Simplex Virus Esophagitis in Immunocompetent Children: A Harbinger of Eosinophilic Esophagitis?
Journal of pediatric gastroenterology and nutrition, 2018Co-Authors: Julia Fritz, Diana Lerner, Mariko SuchiAbstract:Herpes simplex virus (HSV) is a common cause of infectious Esophagitis. The aim of this retrospective study is to identify comorbid and predisposing conditions and sequelae of HSV Esophagitis in immunocompetent children. We reviewed 16 cases of HSV Esophagitis diagnosed from January 1982 to March 2016. Five patients were immunosuppressed, 11 were immunocompetent and included in the study. Three (27%) had no other significant medical history. Five patients (45%) had repeat biopsies following their HSV infection, which showed eosinophilic infiltrate consistent with current diagnostic criteria of eosinophilic Esophagitis (EoE), one of whom had known EoE. Environmental allergies and/or asthma were present in 4 of 5 of these patients. Among the immunocompetent patients, EoE was a comorbidity in almost half, although biopsies at the time of HSV Esophagitis did not show diagnostic features of EoE. Clinical follow-up is therefore warranted for immunocompetent children presenting with HSV Esophagitis, particularly those with atopic conditions.
