Reflux

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Richard W Grady - One of the best experts on this subject based on the ideXlab platform.

Eric Colhoun - One of the best experts on this subject based on the ideXlab platform.

  • subureteral dextranomer hyaluronic acid injection as first line treatment in the management of high grade vesicoureteral Reflux
    The Journal of Urology, 2006
    Co-Authors: Prem Puri, Nochiparambil Mohanan, Martina A Pirker, Michal Dawrant, Laxman Dass, Eric Colhoun
    Abstract:

    Purpose: Endoscopic correction of vesicoureteral Reflux has become an established alternative to long-term antibiotic prophylaxis and ureteral reimplantation. A number of tissue augmenting substances have been used for the endoscopic correction of vesicoureteral Reflux. We prospectively evaluated the effectiveness of dextranomer/hyaluronic acid copolymer (Deflux®) as first line treatment for high grade vesicoureteral Reflux.Materials and Methods: Between 2001 and 2004, 692 children with a median age of 2.1 years (3 months to 13.7 years) with high grade vesicoureteral Reflux underwent endoscopic subureteral injection of Deflux® soon after the diagnosis of vesicoureteral Reflux was made on the initial voiding cystourethrogram. Vesicoureteral Reflux was unilateral in 283 patients and bilateral in 409. Of the 1,101 ureters vesicoureteral Reflux was grade II to V in 35 (3.2%), 580 (52.7%), 457 (41.5%) and 29 (2.6%), respectively. The procedure was performed on an outpatient basis. Followup ultrasound and voidi...

  • treatment of vesicoureteral Reflux by endoscopic injection of dextranomer hyaluronic acid copolymer preliminary results
    The Journal of Urology, 2003
    Co-Authors: Prem Puri, Boris Chertin, Murugesh Velayudham, Laxaman Dass, Eric Colhoun
    Abstract:

    ABSTRACTPurpose: Endoscopic subureteral injection of tissue augmenting substances has become an established alternative to long-term antibiotic prophylaxis and open surgery for the management of vesicoureteral Reflux (VUR) in children. Recently, dextranomer/hyaluronic acid copolymer (Deflux, Q-Med AB, Uppsala, Sweden) a biodegradable injectable material has been reported to be a promising alternative to other tissue augmenting substances. However, the experience with dextranomer/hyaluronic acid copolymer is limited. We prospectively evaluate the effectiveness of dextranomer/hyaluronic acid copolymer in the endoscopic treatment of VUR.Materials and Methods: A total of 32 males and 81 females with a median age of 1 year (range 3 months to 10 years) underwent endoscopic correction of primary VUR with dextranomer/hyaluronic acid copolymer. Reflux was unilateral in 58 cases and bilateral in 54, affecting 166 ureters. Reflux was grades II to V in 7 (4.2%) cases, 91 (54.8%), 63 (38%) and 5 (3%), respectively. Al...

Thomas S Lendvay - One of the best experts on this subject based on the ideXlab platform.

Prem Puri - One of the best experts on this subject based on the ideXlab platform.

  • subureteral dextranomer hyaluronic acid injection as first line treatment in the management of high grade vesicoureteral Reflux
    The Journal of Urology, 2006
    Co-Authors: Prem Puri, Nochiparambil Mohanan, Martina A Pirker, Michal Dawrant, Laxman Dass, Eric Colhoun
    Abstract:

    Purpose: Endoscopic correction of vesicoureteral Reflux has become an established alternative to long-term antibiotic prophylaxis and ureteral reimplantation. A number of tissue augmenting substances have been used for the endoscopic correction of vesicoureteral Reflux. We prospectively evaluated the effectiveness of dextranomer/hyaluronic acid copolymer (Deflux®) as first line treatment for high grade vesicoureteral Reflux.Materials and Methods: Between 2001 and 2004, 692 children with a median age of 2.1 years (3 months to 13.7 years) with high grade vesicoureteral Reflux underwent endoscopic subureteral injection of Deflux® soon after the diagnosis of vesicoureteral Reflux was made on the initial voiding cystourethrogram. Vesicoureteral Reflux was unilateral in 283 patients and bilateral in 409. Of the 1,101 ureters vesicoureteral Reflux was grade II to V in 35 (3.2%), 580 (52.7%), 457 (41.5%) and 29 (2.6%), respectively. The procedure was performed on an outpatient basis. Followup ultrasound and voidi...

  • treatment of vesicoureteral Reflux by endoscopic injection of dextranomer hyaluronic acid copolymer preliminary results
    The Journal of Urology, 2003
    Co-Authors: Prem Puri, Boris Chertin, Murugesh Velayudham, Laxaman Dass, Eric Colhoun
    Abstract:

    ABSTRACTPurpose: Endoscopic subureteral injection of tissue augmenting substances has become an established alternative to long-term antibiotic prophylaxis and open surgery for the management of vesicoureteral Reflux (VUR) in children. Recently, dextranomer/hyaluronic acid copolymer (Deflux, Q-Med AB, Uppsala, Sweden) a biodegradable injectable material has been reported to be a promising alternative to other tissue augmenting substances. However, the experience with dextranomer/hyaluronic acid copolymer is limited. We prospectively evaluate the effectiveness of dextranomer/hyaluronic acid copolymer in the endoscopic treatment of VUR.Materials and Methods: A total of 32 males and 81 females with a median age of 1 year (range 3 months to 10 years) underwent endoscopic correction of primary VUR with dextranomer/hyaluronic acid copolymer. Reflux was unilateral in 58 cases and bilateral in 54, affecting 166 ureters. Reflux was grades II to V in 7 (4.2%) cases, 91 (54.8%), 63 (38%) and 5 (3%), respectively. Al...

Mathew D Sorensen - One of the best experts on this subject based on the ideXlab platform.