The Experts below are selected from a list of 2350743 Experts worldwide ranked by ideXlab platform
Carmen P Mclean - One of the best experts on this subject based on the ideXlab platform.
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prolonged exposure therapy for post traumatic stress disorder a review of evidence and dissemination
Expert Review of Neurotherapeutics, 2011Co-Authors: Carmen P McleanAbstract:Post-traumatic stress disorder (PTSD) is a highly prevalent, often chronic and disabling psychiatric disorder that is associated with significant adverse health and life consequences. Fortunately, there is compelling evidence that cognitive–behavioral therapies, notably exposure therapies, are effective in reducing PTSD symptomology relative to waiting list and active control conditions. Prolonged exposure is a specific exposure therapy program that is considered a first-line Evidence-Based Treatment for PTSD. Unfortunately, barriers to Treatment dissemination prevent the majority of individuals with PTSD from receiving Evidence-Based Treatment. Strategies to increase the availability of Treatment and boost the efficiency of exposure therapy are now being examined.
Judith Cukor - One of the best experts on this subject based on the ideXlab platform.
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Evidence-Based Treatment of Post-Traumatic Stress Disorder
Annual Review of Medicine, 2014Co-Authors: Joann Difede, Megan Olden, Judith CukorAbstract:The term translational research is typically used to refer both to “bench to bedside” research, in which preclinical research findings inform the development of novel therapeutics, and to the dissemination of new Treatments to the community to encourage the use of the new health practices and Treatments. Both definitions are germane to understanding the evidence base for Treatment of post-traumatic stress disorder (PTSD) today. This article offers (a) an overview of Evidence-Based Treatments for PTSD, (b) a description of a translational model of PTSD, and (c) a discussion of common barriers to dissemination and implementation of the empirically validated Treatments. Recent studies in the field are discussed with a focus on pharmacotherapies, psychotherapies, and combined Treatments.
Anthony J. Busti - One of the best experts on this subject based on the ideXlab platform.
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Authors’ response to “Tranexamic acid and uremic bleeding: Evidence-Based Treatment recommendations”
Nature Clinical Practice Nephrology, 2007Co-Authors: Stephanie J Hedges, Sarah B Dehoney, Justin S. Hooper, Jamshid Amanzadeh, Anthony J. BustiAbstract:Authors’ response to “Tranexamic acid and uremic bleeding: Evidence-Based Treatment recommendations”
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Evidence-Based Treatment recommendations for uremic bleeding
Nature Clinical Practice Nephrology, 2007Co-Authors: Stephanie J Hedges, Sarah B Dehoney, Justin S. Hooper, Jamshid Amanzadeh, Anthony J. BustiAbstract:Uremic bleeding syndrome is a recognized consequence of renal failure and can result in clinically significant sequelae. Although the pathophysiology of the condition has yet to be fully elucidated, it is believed to be multifactorial. This article is a review of both the normal hemostatic and homeostatic mechanisms that operate within the body to prevent unnecessary bleeding, as well as an in-depth discussion of the dysfunctional components that contribute to the complications associated with uremic bleeding syndrome. As a result of the multifactorial nature of this syndrome, prevention and Treatment options can include one or a combination of the following: dialysis, erythropoietin, cryoprecipitate, desmopressin, and conjugated estrogens. Here, these Treatment options are compared with regard to their mechanism of action, and onset and duration of efficacy. An extensive review of the clinical trials that have evaluated each Treatment is also presented. Lastly, we have created an Evidence-Based Treatment algorithm to help guide clinicians through most clinical scenarios, and answered common questions related to the management of uremic bleeding.
Steven Dubovsky - One of the best experts on this subject based on the ideXlab platform.
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Prolonged Exposure Works in Veterans with PTSD
NEJM Journal Watch, 2013Co-Authors: Steven DubovskyAbstract:These researchers aimed to determine whether prolonged exposure (PE), the most Evidence-Based Treatment for post-traumatic stress disorder (PTSD),
Roslyn Rivkah Isseroff - One of the best experts on this subject based on the ideXlab platform.
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Diabetic Foot Ulcer: An Evidence-Based Treatment Update
American Journal of Clinical Dermatology, 2014Co-Authors: Liza R Braun, Whitney A Fisk, Robert S Kirsner, Roslyn Rivkah IsseroffAbstract:Background Diabetic foot ulcers (DFUs) are extremely debilitating and difficult to treat. Multidisciplinary management, patient education, glucose control, debridement, offloading, infection control, and adequate perfusion are the mainstays of standard care endorsed by most practice guidelines. Adjunctive therapies represent new Treatment modalities endorsed in recent years, though many lack significant high-powered studies to support their use as standard of care. Objective This update intends to identify recent, exclusively high level, Evidence-Based evaluations of DFU therapies. Furthermore, it suggests a direction for future research. Methods PubMed, Embase, Ovid Technologies, CINAHL, Cochrane, and Web of Science databases were systematically searched for recent systematic reviews published after 2004, and randomized controlled trials published in 2012–2013 that evaluated Treatment modalities for DFUs. These papers are reviewed and the quality of available evidence is discussed. Results A total of 34 studies met inclusion criteria. Studied therapies include debridement, off-loading, negative pressure therapy, dressings, topical therapies, hyperbaric oxygen therapy, growth factors, bioengineered skin substitutes, electrophysical therapy, and alternative therapy. Good-quality evidence is lacking to justify the use of many of these therapies, with the exception of standard care (offloading, debridement) and possibly negative pressure wound therapy. Limitations There is an overall lack of high-level evidence in new adjunctive management of DFU. Comparison of different Treatment modalities is difficult, since existing studies are not standardized. Conclusions Many therapeutic modalities are available to treat DFU. Quality high-level evidence exists for standard care such as off-loading. Evidence for adjunctive therapies such as negative pressure wound therapy, skin substitutes, and platelet-derived growth factor can help guide adjunctive care but limitations exist in terms of evidence quality.
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diabetic foot ulcer an evidence based Treatment update
American Journal of Clinical Dermatology, 2014Co-Authors: Liza R Braun, Whitney A Fisk, Hadar Levtov, Robert S Kirsner, Roslyn Rivkah IsseroffAbstract:Background Diabetic foot ulcers (DFUs) are extremely debilitating and difficult to treat. Multidisciplinary management, patient education, glucose control, debridement, offloading, infection control, and adequate perfusion are the mainstays of standard care endorsed by most practice guidelines. Adjunctive therapies represent new Treatment modalities endorsed in recent years, though many lack significant high-powered studies to support their use as standard of care.
