The Experts below are selected from a list of 297 Experts worldwide ranked by ideXlab platform
Barbara Schmidt - One of the best experts on this subject based on the ideXlab platform.
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Bilateral optic neuropathy and unilateral tonic pupil associated with acute human herpesvirus 6 infection: a case report
Graefe's Archive for Clinical and Experimental Ophthalmology, 2005Co-Authors: Isabel M. Oberacher-velten, Jost B. Jonas, Anselm Jünemann, Barbara SchmidtAbstract:Background Human herpesvirus 6 (HHV-6), a widespread virus and causative agent of Exanthema subitum in children, has been associated with a number of neurologic disorders including cranial nerve palsies, seizures, encephalitis, meningitis, and multiple sclerosis. Patient A 31-year-old man presented with bilateral optic neuropathy, disc edema, and unilateral tonic pupil, which were found to be associated with acute HHV-6 infection. The patient had been suffering from juvenile diabetes for 5 years. One week after onset of intravenous antiviral therapy with foscarnet, disc edema subsided, and tonic pupil reaction was no longer detectable. Conclusions HHV-6 infection may play a role as a causative agent in patients with optic neuropathy and tonic pupil.
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Bilateral optic neuropathy and unilateral tonic pupil associated with acute human herpesvirus 6 infection: a case report.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2004Co-Authors: Isabel M. Oberacher-velten, Jost B. Jonas, Anselm Jünemann, Barbara SchmidtAbstract:Background Human herpesvirus 6 (HHV-6), a widespread virus and causative agent of Exanthema subitum in children, has been associated with a number of neurologic disorders including cranial nerve palsies, seizures, encephalitis, meningitis, and multiple sclerosis.
Tohru Sugimoto - One of the best experts on this subject based on the ideXlab platform.
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Infantile bilateral striatal necrosis associated with human herpes virus-6 (HHV-6) infection
Brain & development, 2005Co-Authors: Aki Murakami, Masafumi Morimoto, Shinsuke Adachi, Yosuke Ishimaru, Tohru SugimotoAbstract:A 1-year-old female with acute bilateral striatal necrosis secondary to Exanthema subitum associated with human herpesvirus 6 (HHV-6) infection is reported. The patient was previously healthy. She presented with progressive neurologic signs of oral dyskinesia and involuntary movements, after suffering from Exanthema subitum. Initial magnetic resonance imaging (MRI) demonstrated abnormal signals in the bilateral striatal regions. In addition, the serum HHV-6 IgM class antibody level was significantly increased. The patient is thought to be the first case of HHV-6 infection related infantile bilateral striatal necrosis (IBSN).
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Case report Infantile bilateral striatal necrosis associated with human herpes virus-6 (HHV-6) infection
2005Co-Authors: Aki Murakami, Masafumi Morimoto, Shinsuke Adachi, Yosuke Ishimaru, Tohru SugimotoAbstract:A 1-year-old female with acute bilateral striatal necrosis secondary to Exanthema subitum associated with human herpesvirus 6 (HHV-6) infection is reported. The patient was previously healthy. She presented with progressive neurologic signs of oral dyskinesia and involuntary movements, after suffering from Exanthema subitum. Initial magnetic resonance imaging (MRI) demonstrated abnormal signals in the bilateral striatal regions. In addition, the serum HHV-6 IgM class antibody level was significantly increased. The patient is thought to be the first case of HHV-6 infection related infantile bilateral striatal necrosis (IBSN). q 2005 Elsevier B.V. All rights reserved.
Wil Van Den Bosch - One of the best experts on this subject based on the ideXlab platform.
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Zesde ziekte/Exanthema subitum
Kleine kwalen bij kinderen, 2017Co-Authors: Wil Van Den BoschAbstract:De zesde ziekte (Exanthema subitum, roseola infantum) is een Exanthemateuze kinderziekte, veroorzaakt door het humaan herpesvirus type 6 (HHV-6).
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zesde ziekte Exanthema subitum
2017Co-Authors: Wil Van Den BoschAbstract:De zesde ziekte (Exanthema subitum, roseola infantum) is een Exanthemateuze kinderziekte, veroorzaakt door het humaan herpesvirus type 6 (HHV-6).
Haruo Hattori - One of the best experts on this subject based on the ideXlab platform.
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Spontaneous remission of spasms in West syndrome – implications of viral infection
Brain & development, 2001Co-Authors: Haruo HattoriAbstract:On a database of the Japanese medical literature between 1970 and 2000, there were 29 patients with West syndrome showing spontaneous remission. In 25/29 (86%) of the patients, spontaneous remission was preceded by viral infections, among which Exanthema subitum predominated. In 16/29 (55%), the spasms recurred a median of 2 months later. However, some of the remaining infants attained lasting remission of the spasms. This link between viral infections and spontaneous remission suggests immuno-inflammatory processes underlie West syndrome in certain patients. Better understanding of such mechanisms may lead to a new therapeutic approach to West syndrome.
Hovi T - One of the best experts on this subject based on the ideXlab platform.
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Serology versus clinical signs or symptoms and main laboratory findings in the diagnosis of Exanthema subitum (roseola infantum).
Pediatrics, 1992Co-Authors: Kimmo Linnavuori, Heikki Peltola, Hovi TAbstract:Twenty-five patients with clinical Exanthema subitum (roseola infantum) were enrolled into a study, where acute-phase and convalescent sera were examined for antibodies to human herpesvirus 6 (HHV-6), several other viruses, and other microbes. In addition, an acute-phase fecal specimen was examined for viruses by electron microscopy. Confirmative or suggestive serologic evidence for recent HHV-6 infection was obtained in 23 (92%) cases. Conversion to HHV-6 was found in 19 (76%), a diagnostic (greater than or equal to 4-fold) titer rise in 2, a twofold titer rise in 1, and a stable relatively high titer in 1 of the patients; only 2 (8%) individuals remained negative. The other microbial assays produced only two slight mycoplasma antibody rises and one rotavirus identification in the fecal specimen. It is concluded that if the clinical diagnosis of Exanthema subitum is deemed doubtful, HHV-6 infection is verifiable in about 75% of the cases by serology.
