The Experts below are selected from a list of 302934 Experts worldwide ranked by ideXlab platform
Mandali Venkateswara Rao - One of the best experts on this subject based on the ideXlab platform.
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antimicrobial antioxidant and anticancer activity of biogenic silver nanoparticles an Experimental Report
RSC Advances, 2016Co-Authors: S. Bhakya, S. Muthukrishnan, M. Sukumaran, Marcelo Grijalva, Luis Cumbal, J Franklin H Benjamin, Senthil T Kumar, Mandali Venkateswara RaoAbstract:In the present study, use of a Helicteres isora stem bark extract for the biosynthesis of AgNPs is described. It was observed that the aqueous silver (Ag+) ions, once associated in the stem bark extract, were reduced in solution, thereby leading to formation of the stable AgNPs. These AgNPs were characterized using several techniques. The nanoparticles show a maximum absorbance at 419–431 nm in the ultraviolet-visible spectra. The presence of the steroid sapogenin was identified using Fourier transform-infrared (FTIR) spectroscopy. The reduction of the Ag+ ions to elemental silver was investigated by using X-ray diffraction (XRD). Transmission electron microscopy (TEM) revealed the formation of monodisperse, with low polydispersity, nanoparticles of 25.55 nm, and the presence of elemental silver was confirmed through energy dispersive spectroscopy (EDX) analysis. The AgNPs showed antioxidant activities such as DPPH, hydrogen peroxide and nitric oxide radical scavenging and a reducing power compared to the standard compounds. The antibacterial effect was determined against test strains, showing significant inhibition. The antiproliferative activity of the AgNPs was demonstrated using oral carcinoma (KB) cells with MTT, and confirmed using AO/EtBr, comet assay, DCFH-DA and Rhodamine 123 staining. In the toxicity study, a significant mortality rate was observed against Artemia with an IC50 concentration of 70 μg mL−1 and 108 h exposure. The NPs showed as cytotoxic against Artemia at 108 h, so they are cytotoxic at high concentrations and after prolonged exposure.
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Antimicrobial, antioxidant and anticancer activity of biogenic silver nanoparticles – an Experimental Report
RSC Advances, 2016Co-Authors: S. Bhakya, S. Muthukrishnan, M. Sukumaran, Marcelo Grijalva, Luis Cumbal, J. H. Franklin Benjamin, T. Senthil Kumar, Mandali Venkateswara RaoAbstract:In the present study, use of a Helicteres isora stem bark extract for the biosynthesis of AgNPs is described. It was observed that the aqueous silver (Ag+) ions, once associated in the stem bark extract, were reduced in solution, thereby leading to formation of the stable AgNPs. These AgNPs were characterized using several techniques. The nanoparticles show a maximum absorbance at 419–431 nm in the ultraviolet-visible spectra. The presence of the steroid sapogenin was identified using Fourier transform-infrared (FTIR) spectroscopy. The reduction of the Ag+ ions to elemental silver was investigated by using X-ray diffraction (XRD). Transmission electron microscopy (TEM) revealed the formation of monodisperse, with low polydispersity, nanoparticles of 25.55 nm, and the presence of elemental silver was confirmed through energy dispersive spectroscopy (EDX) analysis. The AgNPs showed antioxidant activities such as DPPH, hydrogen peroxide and nitric oxide radical scavenging and a reducing power compared to the standard compounds. The antibacterial effect was determined against test strains, showing significant inhibition. The antiproliferative activity of the AgNPs was demonstrated using oral carcinoma (KB) cells with MTT, and confirmed using AO/EtBr, comet assay, DCFH-DA and Rhodamine 123 staining. In the toxicity study, a significant mortality rate was observed against Artemia with an IC50 concentration of 70 μg mL−1 and 108 h exposure. The NPs showed as cytotoxic against Artemia at 108 h, so they are cytotoxic at high concentrations and after prolonged exposure.
Mohammad Hemmat Esfe - One of the best experts on this subject based on the ideXlab platform.
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An Experimental Report and new correlation for estimating the dynamic viscosity of MWCNT(50)-ZnO(50)/SAE 50 as nano-lubricant
Journal of Thermal Analysis and Calorimetry, 2020Co-Authors: Mohammad Hemmat EsfeAbstract:In this study, the viscosity of SAE 50 engine oil containing MWCNT-ZnO nanoparticles was investigated Experimentally. For this purpose, volume fractions (VFs) of 0.0625–1% of nano-oil were prepared and their dynamic viscosity was measured at different temperatures of 25–50 °C with changing shear rate (SR) and its rheological behavior was studied. The investigations showed the dependency of viscosity to SR variation, which is a sign for non-Newtonian behavior of nano-fluid (NF). The results clearly showed that pure oil and nano-oil behave non-Newtonian and behave similar to non-Newtonian shear-thinning fluids. To prevent spending extra money in future studies a new mathematical based correlation is proposed with the accuracy of R^2 = 0.9984. By doing a comparisons between predicted resutls by the correlation and Experimental results a proper accuracy in the mentioned temperature and concentration ranges was obtained. Graphic abstract
S. Bhakya - One of the best experts on this subject based on the ideXlab platform.
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antimicrobial antioxidant and anticancer activity of biogenic silver nanoparticles an Experimental Report
RSC Advances, 2016Co-Authors: S. Bhakya, S. Muthukrishnan, M. Sukumaran, Marcelo Grijalva, Luis Cumbal, J Franklin H Benjamin, Senthil T Kumar, Mandali Venkateswara RaoAbstract:In the present study, use of a Helicteres isora stem bark extract for the biosynthesis of AgNPs is described. It was observed that the aqueous silver (Ag+) ions, once associated in the stem bark extract, were reduced in solution, thereby leading to formation of the stable AgNPs. These AgNPs were characterized using several techniques. The nanoparticles show a maximum absorbance at 419–431 nm in the ultraviolet-visible spectra. The presence of the steroid sapogenin was identified using Fourier transform-infrared (FTIR) spectroscopy. The reduction of the Ag+ ions to elemental silver was investigated by using X-ray diffraction (XRD). Transmission electron microscopy (TEM) revealed the formation of monodisperse, with low polydispersity, nanoparticles of 25.55 nm, and the presence of elemental silver was confirmed through energy dispersive spectroscopy (EDX) analysis. The AgNPs showed antioxidant activities such as DPPH, hydrogen peroxide and nitric oxide radical scavenging and a reducing power compared to the standard compounds. The antibacterial effect was determined against test strains, showing significant inhibition. The antiproliferative activity of the AgNPs was demonstrated using oral carcinoma (KB) cells with MTT, and confirmed using AO/EtBr, comet assay, DCFH-DA and Rhodamine 123 staining. In the toxicity study, a significant mortality rate was observed against Artemia with an IC50 concentration of 70 μg mL−1 and 108 h exposure. The NPs showed as cytotoxic against Artemia at 108 h, so they are cytotoxic at high concentrations and after prolonged exposure.
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Antimicrobial, antioxidant and anticancer activity of biogenic silver nanoparticles – an Experimental Report
RSC Advances, 2016Co-Authors: S. Bhakya, S. Muthukrishnan, M. Sukumaran, Marcelo Grijalva, Luis Cumbal, J. H. Franklin Benjamin, T. Senthil Kumar, Mandali Venkateswara RaoAbstract:In the present study, use of a Helicteres isora stem bark extract for the biosynthesis of AgNPs is described. It was observed that the aqueous silver (Ag+) ions, once associated in the stem bark extract, were reduced in solution, thereby leading to formation of the stable AgNPs. These AgNPs were characterized using several techniques. The nanoparticles show a maximum absorbance at 419–431 nm in the ultraviolet-visible spectra. The presence of the steroid sapogenin was identified using Fourier transform-infrared (FTIR) spectroscopy. The reduction of the Ag+ ions to elemental silver was investigated by using X-ray diffraction (XRD). Transmission electron microscopy (TEM) revealed the formation of monodisperse, with low polydispersity, nanoparticles of 25.55 nm, and the presence of elemental silver was confirmed through energy dispersive spectroscopy (EDX) analysis. The AgNPs showed antioxidant activities such as DPPH, hydrogen peroxide and nitric oxide radical scavenging and a reducing power compared to the standard compounds. The antibacterial effect was determined against test strains, showing significant inhibition. The antiproliferative activity of the AgNPs was demonstrated using oral carcinoma (KB) cells with MTT, and confirmed using AO/EtBr, comet assay, DCFH-DA and Rhodamine 123 staining. In the toxicity study, a significant mortality rate was observed against Artemia with an IC50 concentration of 70 μg mL−1 and 108 h exposure. The NPs showed as cytotoxic against Artemia at 108 h, so they are cytotoxic at high concentrations and after prolonged exposure.
Johan Sundelin - One of the best experts on this subject based on the ideXlab platform.
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Steel truss exposed to localized fires : Experimental Report from a large scale experiment with a steel truss exposed to localized fires
2015Co-Authors: Joakim Sandström, Ulf Wickström, Milan Veljkovic, Naveed Iqbal, Johan Sjöström, Johan SundelinAbstract:Steel truss exposed to localized fires : Experimental Report from a large scale experiment with a steel truss exposed to localized fires
Kumpati Premkumar - One of the best experts on this subject based on the ideXlab platform.
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biogenic silver nanoparticles for cancer treatment an Experimental Report
Colloids and Surfaces B: Biointerfaces, 2013Co-Authors: Murugaraj Jeyaraj, G Sathishkumar, Ganeshan Sivanandhan, Davoodbasha Mubarakali, Manoharan Rajesh, Renganathan Arun, Gnanajothi Kapildev, Markandan Manickavasagam, Nooruddin Thajuddin, Kumpati PremkumarAbstract:A generation of nanoparticles research has discussed recently. It is mandatory to elaborate the applications of biogenic nanoparticles in general and anticancereous property in particular. The present study was aimed to investigate the in vitro cytotoxicity effect of biogenic silver nanoparticles (AgNPs) against human breast cancer (MCF-7) cells towards the development of anticancer agent. Biogenic AgNPs were achieved by employing Sesbania grandiflora leaf extract as a novel reducing agent. It was well characterized by FESEM, EDAX and spectral studies showed spherical shaped nanoparticles in the size of 22 nm in slightly agglomerated form. It was surprising that biogenic AgNPs showed cytotoxic effect against MCF-7 cell lines were confirmed by MTT, AO-EB, Hochest and COMET assays. There was an immediate induction of cellular damage in terms of loss of cell membrane integrity, oxidative stress and apoptosis were found in the cell which treated with AgNPs. This may be a first Report on anti-MCF-7 property of biogenic AgNPs in the fourth generation of nanoparticles research. It is necessary to study the formulation and clinical trials to establish the nano drug to treat cancer cells.
