The Experts below are selected from a list of 114 Experts worldwide ranked by ideXlab platform
Jeanne D Johansen - One of the best experts on this subject based on the ideXlab platform.
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no association between nickel allergy and reporting cosmetic Dermatitis from mascara or eye shadow a cross sectional general population study
Journal of The European Academy of Dermatology and Venereology, 2009Co-Authors: Jacob P Thyssen, Allan Linneberg, Torkil Menne, N H Nielsen, Jeanne D JohansenAbstract:Background In theory, all pigmented make-up products may contain metal allergens including nickel. Eyelid Dermatitis has previously been observed among nickel allergic Dermatitis patients following exposure to nickel containing mascara and eye shadow. However, an association between nickel Eyelid Dermatitis and nickel in make-up products remains controversial. Objective This cross-sectional patch test study investigated whether the frequency of self-reported cosmetic Dermatitis from mascara or eye shadow use was higher among nickel allergic Danish women than women without nickel allergy. Methods In 2006, a total of 1843 18–69 year old women completed a postal questionnaire including questions on cosmetic Dermatitis and were patch tested with nickel sulphate. Data were analysed by logistic regression analyses and associations were expressed as odds ratios (ORs) with 95% confidence intervals (CIs). Results The prevalence of nickel allergy was similar among women who reported cosmetic Dermatitis from eye shadow or mascara and among women who did not report such symptoms. Cosmetic Dermatitis was positively associated with self-reported atopic Dermatitis and age. Conclusion Overall, no association between having nickel allergy and reporting cosmetic Dermatitis from mascara or eye shadow use was found in the general population. This does not exclude a causal relationship in selected cases.
Jacob P Thyssen - One of the best experts on this subject based on the ideXlab platform.
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no association between nickel allergy and reporting cosmetic Dermatitis from mascara or eye shadow a cross sectional general population study
Journal of The European Academy of Dermatology and Venereology, 2009Co-Authors: Jacob P Thyssen, Allan Linneberg, Torkil Menne, N H Nielsen, Jeanne D JohansenAbstract:Background In theory, all pigmented make-up products may contain metal allergens including nickel. Eyelid Dermatitis has previously been observed among nickel allergic Dermatitis patients following exposure to nickel containing mascara and eye shadow. However, an association between nickel Eyelid Dermatitis and nickel in make-up products remains controversial. Objective This cross-sectional patch test study investigated whether the frequency of self-reported cosmetic Dermatitis from mascara or eye shadow use was higher among nickel allergic Danish women than women without nickel allergy. Methods In 2006, a total of 1843 18–69 year old women completed a postal questionnaire including questions on cosmetic Dermatitis and were patch tested with nickel sulphate. Data were analysed by logistic regression analyses and associations were expressed as odds ratios (ORs) with 95% confidence intervals (CIs). Results The prevalence of nickel allergy was similar among women who reported cosmetic Dermatitis from eye shadow or mascara and among women who did not report such symptoms. Cosmetic Dermatitis was positively associated with self-reported atopic Dermatitis and age. Conclusion Overall, no association between having nickel allergy and reporting cosmetic Dermatitis from mascara or eye shadow use was found in the general population. This does not exclude a causal relationship in selected cases.
Peter K. Smith - One of the best experts on this subject based on the ideXlab platform.
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Recognition of allergic conjunctivitis in patients with allergic rhinitis
World Allergy Organization Journal, 2013Co-Authors: Daniel C Williams, Bianca Maiden, Gabrielle Edney, Peter K. SmithAbstract:AIMS: To identify the incidence of allergic conjunctivitis in patients with allergic rhinitis.\n\nMETHODS: One hundred and eighty seven consecutive patients with allergic rhinitis (AR) were directly questioned if they have allergic conjunctivitis (AC) and this was clarified using standard screening questions relating to red, itchy and watery eyes recorded through a total ocular symptom score (TOSS). Patients were also asked about further symptoms that may be attributable to AC: Eyelid Dermatitis, frequent blinking; eye sensitivity and frontal headache from squinting or. blinking. All patients were given a drop of olopatadine hydrochloride 0.1% in each eye to help identify "silent" disease. 20 healthy non-atopic controls were also treated with olopatadine drops and questioned on ocular symptoms.\n\nRESULTS: Fifty five percent of patients with AR were identified as having AC by direct questioning and the use of the TOSS questionaire. A further 41% were identifiable by asking additional questions and performing therapeutic challenge with olopadatine.\n\nCONCLUSIONS: AC is a frequent comorbid condition occurring in 95% of our patients with AR. Only 55% of patients were able to identify that they had AC based on standard screening questions. Additional specific questioning and a therapeutic challenge in suspected patients can help identify patients who may benefit from treatment of AC.
Mark Lebwohl - One of the best experts on this subject based on the ideXlab platform.
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corticosteroid addiction and withdrawal in the atopic the red burning skin syndrome
Clinics in Dermatology, 2003Co-Authors: Marvin J Rapaport, Mark LebwohlAbstract:We recently reported 100 patients with a chronic Eyelid Dermatitis that did not resolve until all topical and systemic corticosteroids had been discontinued. All of these patients had been treated with long-term topical corticosteroids, usually with escalating dosage and frequency of application. In the majority of patients, the initial symptom of pruritus commonly evolved into a characteristic, severe burning sensation. In many cases, systemic corticosteroids had also been administered to relieve the severe erythema and burning, but this only exacerbated the condition. In our opinion the continuing Dermatitis resulted from “steroid addiction.” Unfortunately, the time required for corticosteroid withdrawal mirrored the time over which they had originally been applied, and was often protracted. Examination of Eyelid skin usually revealed atrophy and telangiectasia. Patch testing, including four different corticosteroid allergens, demonstrated only irritant reactions but no relevant allergens. The corticosteroid antigens included budesonide, hydroxy-17-butyrate, clobetasol-17-propionate, and tixocortol. Of 100 patients, 87 were cured, but only after total cessation of corticosteroid usage. Withdrawal symptoms, manifested by angry erythema and burning, were long-lasting and severe. Although neither Cushing’s syndrome or adrenal insufficiency occurred, marked localized and systemic edema developed in some patients. Thirteen patients, unable to tolerate the severe flares on corticosteroid withdrawal, continued using these preparations and continued to exhibit skin rashes. They eventually sought medical care with other practitioners and were lost to follow-up. This paper expands our previous observations to include patients with similar syndromes localized in other body areas. These include “red face syndrome,” post-laser-peel syndrome, status cosmeticus, “red scrotum syndrome,” vulvodynia, anal atrophoderma, chronic actinic Dermatitis, and “chronic eczema” in other body areas (Table 1). These conditions similarly resolved upon discontinuation of corticosteroids, suggesting that a significant proportion of these syndromes are attributable to chronic corticosteroid usage and “corticosteroid addiction.” The medical literature pertaining to these syndromes usually has implicated sun exposure, occult allergens, or psychosomatic reactions as the cause of ongoing skin eruptions. We consider “corticosteroid addiction” of the skin to be the pertinent etiologic factor in the majority of these patients.
Fabbri P. - One of the best experts on this subject based on the ideXlab platform.
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Sjogren's syndrome: a retrospective review of the cutaneous features of 93 patients by the Italian Group of Immunodermatology.
Clinical and Experimental Rheumatology:Via S Maria 31 I 56126 Pisa Italy:011 39 050 40124 EMAIL: info@clinexprhematol.org INTERNET: http: www.clinexpr, 2004Co-Authors: Bernacchi E, Amato L, Parodi Aurora, Cottoni F, Rubegni P, De Pita O, Papini M, Rebora A, Bombardieri S, Fabbri P.Abstract:Various cutaneous manifestations have been described (xerosis, Eyelid Dermatitis, angular cheilitis, cutaneous vasculitis and annular erythema) in Sj\uf6gren's syndrome (SS), but so far only three studies on large numbers of SS patients have been carried out. The frequency of cutaneous manifestations and their association with specific clinical or immunological parameters have never been studied. The aim of the Italian Group of Immunodermatology was to evaluate these associations in a large number of SS patients
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Sjögren's syndrome: a retrospective review of the cutaneous features of 93 patients by the Italian Group of Immunodermatology
Clinical and Experimental Rheumatology:Via S Maria 31 I 56126 Pisa Italy:011 39 050 40124 EMAIL: info@clinexprhematol.org INTERNET: http: www.clinexpr, 2004Co-Authors: Bernacchi E, Amato L, Cottoni F, De Pita O, Papini M, Rebora A, Bombardieri S, Parodi A, P. Rubegni, Fabbri P.Abstract:OBJECTIVE: Various cutaneous manifestations have been described (xerosis, Eyelid Dermatitis, angular cheilitis, cutaneous vasculitis and annular erythema) in Sjögren's syndrome (SS), but so far only three studies on large numbers of SS patients have been carried out. The frequency of cutaneous manifestations and their association with specific clinical or immunological parameters have never been studied. The aim of the Italian Group of Immunodermatology was to evaluate these associations in a large number of SS patients. METHODS: A retrospective review was performed on 93 patients with SS followed over a ten-year period (1990-2000) at 6 Italian dermatological centers. They were subdivided into two groups, 62 with primary SS and 31 with secondary SS, and the frequency of cutaneous manifestations and specific antibodies was determined and compared between them. RESULTS: We found significantly higher levels of xerosis (p = 0.009) (56.4% versus 25.8%) and angular cheilitis (p = 0.017) (38.7% versus 16.1%) in primary SS patients than in those with secondary SS. A significant association of xerosis with anti-SSA + SSB (p = 0.033) antibodies was also demonstrated. Eyelid Dermatitis and pruritus were common but less specific cutaneous symptoms. Annular erythema was found more often in primary (6.45%) than in secondary (3.2%) SS and was associated with SSA + SSB antibodies in 75% of the cases. Cutaneous vasculitis was present in 30.6% of primary SS (manifesting as palpable purpura in 84%) and in 29.3% of secondary SS cases. CONCLUSION: Xerosis is the most frequent and characteristic cutaneous manifestation of primary SS. It is not linked to decreased sebaceous or sweat gland secretion, but more probably to a specific alteration of the protective function of the stratum corneum. Angular cheilitis is a common but less specific skin lesion in SS and is associated with xerosis and xerostomia
