The Experts below are selected from a list of 282 Experts worldwide ranked by ideXlab platform
Jeffrey Enne - One of the best experts on this subject based on the ideXlab platform.
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three dimensional microsurgical anatomy and the safe entry zones of the brainstem
Neurosurgery, 2014Co-Authors: Kaa Yagmurlu, Necmetti Tanriove, Albe L Rhoto, Jeffrey EnneAbstract:BACKGROUND: There have been no studies of the structure and safe surgical entry zones of the brainstem based on fiber dissection studies combined with 3-dimensional (3-D) photography. OBJECTIVE: To examine the 3-D internal architecture and relationships of the proposed safe entry zones into the midbrain, pons, and medulla. METHODS: Fifteen formalin and alcohol-fixed human brainstems were dissected by using fiber dissection techniques, ×6 to ×40 magnification, and 3-D photography to define the anatomy and the safe entry zones. The entry zones evaluated were the perioculomotor, lateral mesencephalic sulcus, and supra- and infracollicular areas in the midbrain; the peritrigeminal zone, supra- and infraFacial approaches, acoustic area, and median sulcus above the Facial Colliculus in the pons; and the anterolateral, postolivary, and dorsal medullary sulci in the medulla. RESULTS: The safest approach for lesions located below the surface is usually the shortest and most direct route. Previous studies have often focused on surface structures. In this study, the deeper structures that may be at risk in each of the proposed safe entry zones plus the borders of each entry zone were defined. This study includes an examination of the relationships of the cerebellar peduncles, long tracts, intra-axial segments of the cranial nerves, and important nuclei of the brainstem to the proposed safe entry zones. CONCLUSION: Fiber dissection technique in combination with the 3-D photography is a useful addition to the goal of making entry into the brainstem more accurate and safe.
Kaa Yagmurlu - One of the best experts on this subject based on the ideXlab platform.
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three dimensional microsurgical anatomy and the safe entry zones of the brainstem
Neurosurgery, 2014Co-Authors: Kaa Yagmurlu, Necmetti Tanriove, Albe L Rhoto, Jeffrey EnneAbstract:BACKGROUND: There have been no studies of the structure and safe surgical entry zones of the brainstem based on fiber dissection studies combined with 3-dimensional (3-D) photography. OBJECTIVE: To examine the 3-D internal architecture and relationships of the proposed safe entry zones into the midbrain, pons, and medulla. METHODS: Fifteen formalin and alcohol-fixed human brainstems were dissected by using fiber dissection techniques, ×6 to ×40 magnification, and 3-D photography to define the anatomy and the safe entry zones. The entry zones evaluated were the perioculomotor, lateral mesencephalic sulcus, and supra- and infracollicular areas in the midbrain; the peritrigeminal zone, supra- and infraFacial approaches, acoustic area, and median sulcus above the Facial Colliculus in the pons; and the anterolateral, postolivary, and dorsal medullary sulci in the medulla. RESULTS: The safest approach for lesions located below the surface is usually the shortest and most direct route. Previous studies have often focused on surface structures. In this study, the deeper structures that may be at risk in each of the proposed safe entry zones plus the borders of each entry zone were defined. This study includes an examination of the relationships of the cerebellar peduncles, long tracts, intra-axial segments of the cranial nerves, and important nuclei of the brainstem to the proposed safe entry zones. CONCLUSION: Fiber dissection technique in combination with the 3-D photography is a useful addition to the goal of making entry into the brainstem more accurate and safe.
Igor J. Koralnik - One of the best experts on this subject based on the ideXlab platform.
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PML-IRIS in an HIV-2-infected patient presenting as Bell’s palsy
Journal of NeuroVirology, 2017Co-Authors: Fabian Sierra Morales, Carlos Illingworth, Kathie Lin, Ivia Rivera Agosto, Chloé Powell, Jacob A. Sloane, Igor J. KoralnikAbstract:We present the case of an HIV-2-infected patient who developed progressive multifocal leukoencephalopathy (PML) in the setting of immune reconstitution inflammatory syndrome (IRIS) presenting as Bell’s palsy. The brain MRI showed a single lesion in the Facial Colliculus considered initially to be ischemic in nature. This case report should alert clinicians that PML can occur in the setting of HIV-2 infection. It also illustrates the difficulty of establishing the diagnosis of PML.
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PML-IRIS in an HIV-2-infected patient presenting as Bell's palsy.
Journal of NeuroVirology, 2017Co-Authors: Fabian Sierra Morales, Carlos Illingworth, Kathie Lin, Chloé Powell, Jacob A. Sloane, Ivia Rivera Agosto, Igor J. KoralnikAbstract:We present the case of an HIV-2-infected patient who developed progressive multifocal leukoencephalopathy (PML) in the setting of immune reconstitution inflammatory syndrome (IRIS) presenting as Bell’s palsy. The brain MRI showed a single lesion in the Facial Colliculus considered initially to be ischemic in nature. This case report should alert clinicians that PML can occur in the setting of HIV-2 infection. It also illustrates the difficulty of establishing the diagnosis of PML.
Francisco Velascocampos - One of the best experts on this subject based on the ideXlab platform.
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hemiFacial spasm associated with compression of the Facial Colliculus by a choroid plexus papilloma of the fourth ventricle
Stereotactic and Functional Neurosurgery, 2020Co-Authors: Jose Luis Navarroolvera, Juan Camilo Covaledarodriguez, Jose Armando Diazmartinez, Gustavo Aguadocarrillo, Jose D Carrilloruiz, Francisco VelascocamposAbstract:BACKGROUND HemiFacial spasm is an involuntary condition that involves muscles innervated by the ipsilateral Facial nerve. There are secondary causes of hemiFacial spasm that can produce a typical presentation of symptoms. Extrinsic compression of the Facial Colliculus at the floor of the fourth ventricle is responsible for <0.6% of the causes of secondary hemiFacial spasm, as the cases with this origin reported in the literature are rare. CASE REPORTS We present the case of a 43-year-old female with hemiFacial spasm of typical characteristics 6 months after onset. Upon clinical examination, a severe contraction of the orbicularis oculi, orbicularis oris, and superficial muscles of the neck displaying 50 crisis per hour was revealed. Brain magnetic resonance imaging showed absence of the Facial nerve vascular loop in the cisternal portion, with evidence of an intraventricular tumor in relation with the medial portion of the fourth ventricle at the Facial Colliculus level, indicating a secondary origin of hemiFacial spasm. Preoperative electromyography demonstrated irritative electric activity in the muscular branches of the Facial nerve. A telovelar approach was performed to the fourth ventricle with intraoperative electrophysiology monitoring, with immediate resolution of the irritative activity after complete tumor resection. The result of the histopathologic study was a choroid plexus papilloma. CONCLUSION Fourth ventricle tumors with extrinsic compression of the Facial Colliculus represent <0.6% of the causes of hemiFacial spasm. Its relationship with choroid plexuses papilloma is being described as the first case reported in the literature. Clinical correlation, imaging, and intraoperative findings in conjunction with intraoperative electrophysiology recordings allow to predict the resolution of symptoms after resecting the lesion.
Necmetti Tanriove - One of the best experts on this subject based on the ideXlab platform.
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three dimensional microsurgical anatomy and the safe entry zones of the brainstem
Neurosurgery, 2014Co-Authors: Kaa Yagmurlu, Necmetti Tanriove, Albe L Rhoto, Jeffrey EnneAbstract:BACKGROUND: There have been no studies of the structure and safe surgical entry zones of the brainstem based on fiber dissection studies combined with 3-dimensional (3-D) photography. OBJECTIVE: To examine the 3-D internal architecture and relationships of the proposed safe entry zones into the midbrain, pons, and medulla. METHODS: Fifteen formalin and alcohol-fixed human brainstems were dissected by using fiber dissection techniques, ×6 to ×40 magnification, and 3-D photography to define the anatomy and the safe entry zones. The entry zones evaluated were the perioculomotor, lateral mesencephalic sulcus, and supra- and infracollicular areas in the midbrain; the peritrigeminal zone, supra- and infraFacial approaches, acoustic area, and median sulcus above the Facial Colliculus in the pons; and the anterolateral, postolivary, and dorsal medullary sulci in the medulla. RESULTS: The safest approach for lesions located below the surface is usually the shortest and most direct route. Previous studies have often focused on surface structures. In this study, the deeper structures that may be at risk in each of the proposed safe entry zones plus the borders of each entry zone were defined. This study includes an examination of the relationships of the cerebellar peduncles, long tracts, intra-axial segments of the cranial nerves, and important nuclei of the brainstem to the proposed safe entry zones. CONCLUSION: Fiber dissection technique in combination with the 3-D photography is a useful addition to the goal of making entry into the brainstem more accurate and safe.
