The Experts below are selected from a list of 42 Experts worldwide ranked by ideXlab platform

Piotr Milkiewicz - One of the best experts on this subject based on the ideXlab platform.

  • Acute liver injury, acute liver failure and acute on chronic liver failure: A clinical spectrum of poisoning due to Gyromitra esculenta
    Annals of hepatology, 2019
    Co-Authors: Magdalena Arłukowicz-grabowska, Maciej Wójcicki, Joanna Raszeja-wyszomirska, Monika Szydłowska-jakimiuk, Bernard Piotuch, Piotr Milkiewicz
    Abstract:

    Gyromitra esculenta, also known as "False Morel" is one of the most poisonous mushrooms. This species is found all over the world, growing in coniferous forest in early spring time. Common manifestation of poisoning includes gastrointestinal symptoms which include varied degrees of liver impairment. We describe three cases: acute liver injury, acute liver failure and acute-on-chronic liver failure due to G. esculenta poisoning. At admission patients presented with encephalopathy and features of liver failure. Two of them recovered completely following supportive management while the remaining patient who also had preexisting liver disease developed multiorgan failure and subsequently died. Although a rare occurrence, G. esculenta poisoning should be considered in the differential diagnosis of acute liver failure.

Magdalena Arłukowicz-grabowska - One of the best experts on this subject based on the ideXlab platform.

  • Acute liver injury, acute liver failure and acute on chronic liver failure: A clinical spectrum of poisoning due to Gyromitra esculenta
    Annals of hepatology, 2019
    Co-Authors: Magdalena Arłukowicz-grabowska, Maciej Wójcicki, Joanna Raszeja-wyszomirska, Monika Szydłowska-jakimiuk, Bernard Piotuch, Piotr Milkiewicz
    Abstract:

    Gyromitra esculenta, also known as "False Morel" is one of the most poisonous mushrooms. This species is found all over the world, growing in coniferous forest in early spring time. Common manifestation of poisoning includes gastrointestinal symptoms which include varied degrees of liver impairment. We describe three cases: acute liver injury, acute liver failure and acute-on-chronic liver failure due to G. esculenta poisoning. At admission patients presented with encephalopathy and features of liver failure. Two of them recovered completely following supportive management while the remaining patient who also had preexisting liver disease developed multiorgan failure and subsequently died. Although a rare occurrence, G. esculenta poisoning should be considered in the differential diagnosis of acute liver failure.

Karakus T - One of the best experts on this subject based on the ideXlab platform.

Peter M. Gannett - One of the best experts on this subject based on the ideXlab platform.

  • Gyromitra esculenta mushroom: a comparative assessment of its carcinogenic potency.
    In vivo (Athens Greece), 1994
    Co-Authors: Peter M. Gannett
    Abstract:

    A comparative assessment is performed on one of the False Morel mushrooms, Gyromitra esculenta, including the amounts of some hydrazines present in this fungus, the cancer-inducing doses of these chemicals or the mushroom used in animal experiments, the total amounts of the hydrazines or mushroom needed to induce neoplasms in mice and the estimated total amounts of hydrazines or mushroom needed to induce cancer in humans. When one compares the estimated amounts of hydrazines required to induce cancer with the amount of raw Gyromitra esculenta needed to yield a similar effect, it becomes clear that to date 37 percent of the carcinogenic ingredients of this fungus have been identified.

  • Cancer Induction in Mice by Feeding the Raw False Morel Mushroom Gyromitra esculenta
    Cancer research, 1992
    Co-Authors: Kashinath Patil, Heikki Pyysalo, Carol Stessman, Peter M. Gannett
    Abstract:

    Abstract One of the False Morel mushrooms, Gyromitra esculenta, was administered p.o. to Swiss mice that were 6 weeks old at the beginning of the experiment. The mushrooms were fed to the mice for 3 days and were followed by a semisynthetic diet for 4 days each week for life. The treatment induced tumors in the lungs, nasal cavity, blood vessels, forestomach, glandular stomach, cecum, and liver in the following incidences: 80, 10, 50, 16, 4, 28, and 6% in females, and 70, 12, 32, 18, 20, 22, and 12% in males. In the untreated controls, the corresponding tumor incidences were 28, 0, 14, 0, 0, 8, and 0% in females and 38, 0, 6, 0, 0, 8, and 2% in males. The light microscopic examination revealed the typical appearance of adenomas and adenocarcinomas of lungs, adenomas and adenocarcinomas of nasal cavities, hemangiomas and hemangiosarcomas of blood vessels, squamous cell papillomas and carcinomas of the forestomach, adenomas and adenocarcinomas of the glandular stomach, polypoid adenomas and adenocarcinomas of the cecum, and hepatomas. The work demonstrates the carcinogenic action of the raw G. esculenta mushroom.

Bernard Piotuch - One of the best experts on this subject based on the ideXlab platform.

  • Acute liver injury, acute liver failure and acute on chronic liver failure: A clinical spectrum of poisoning due to Gyromitra esculenta
    Annals of hepatology, 2019
    Co-Authors: Magdalena Arłukowicz-grabowska, Maciej Wójcicki, Joanna Raszeja-wyszomirska, Monika Szydłowska-jakimiuk, Bernard Piotuch, Piotr Milkiewicz
    Abstract:

    Gyromitra esculenta, also known as "False Morel" is one of the most poisonous mushrooms. This species is found all over the world, growing in coniferous forest in early spring time. Common manifestation of poisoning includes gastrointestinal symptoms which include varied degrees of liver impairment. We describe three cases: acute liver injury, acute liver failure and acute-on-chronic liver failure due to G. esculenta poisoning. At admission patients presented with encephalopathy and features of liver failure. Two of them recovered completely following supportive management while the remaining patient who also had preexisting liver disease developed multiorgan failure and subsequently died. Although a rare occurrence, G. esculenta poisoning should be considered in the differential diagnosis of acute liver failure.