The Experts below are selected from a list of 225 Experts worldwide ranked by ideXlab platform

Douglas W Biggar - One of the best experts on this subject based on the ideXlab platform.

  • Fat Embolism syndrome following minor trauma in duchenne muscular dystrophy
    Neuromuscular Disorders, 2012
    Co-Authors: Laura Mcadam, Anjali Rastogi, Kathleen Macleod, Douglas W Biggar
    Abstract:

    Abstract We describe five patients with Duchenne muscular dystrophy who presented with acute neurologic and respiratory symptoms following minor trauma. Four of the five deteriorated rapidly and died within 36 h after falling. X-rays for fractures were negative. Four of the five patients were taking corticosteroids daily. All five patients fulfilled the clinical criteria for Fat Embolism Syndrome. Autopsy findings were consistent with Fat Embolism in two cases. Fat Embolism Syndrome needs to be considered in patients with Duchenne muscular dystrophy following minor trauma even without fractures. Early recognition of Fat Embolism Syndrome and aggressive resuscitation are important to improve survival. This report serves as an important reminder that seatbelts need to be used at all times.

Laura Mcadam - One of the best experts on this subject based on the ideXlab platform.

  • Fat Embolism syndrome following minor trauma in duchenne muscular dystrophy
    Neuromuscular Disorders, 2012
    Co-Authors: Laura Mcadam, Anjali Rastogi, Kathleen Macleod, Douglas W Biggar
    Abstract:

    Abstract We describe five patients with Duchenne muscular dystrophy who presented with acute neurologic and respiratory symptoms following minor trauma. Four of the five deteriorated rapidly and died within 36 h after falling. X-rays for fractures were negative. Four of the five patients were taking corticosteroids daily. All five patients fulfilled the clinical criteria for Fat Embolism Syndrome. Autopsy findings were consistent with Fat Embolism in two cases. Fat Embolism Syndrome needs to be considered in patients with Duchenne muscular dystrophy following minor trauma even without fractures. Early recognition of Fat Embolism Syndrome and aggressive resuscitation are important to improve survival. This report serves as an important reminder that seatbelts need to be used at all times.

Harry S Jacob - One of the best experts on this subject based on the ideXlab platform.

  • Fat Embolism prophylaxis with corticosteroids
    Annals of Internal Medicine, 2020
    Co-Authors: Steven A Schonfeld, Yongyudh Ploysongsang, Ralph Dilisio, John D Crissman, Edward J Miller, Dale E Hammerschmidt, Harry S Jacob
    Abstract:

    Abstract The efficacy of corticosteroid treatment in the prophylaxis of the Fat Embolism syndrome was evaluated in a prospective, randomized, double-blind study of high-risk patients with long-bone...

Cherkasov Va - One of the best experts on this subject based on the ideXlab platform.

  • Cerebrospinal fluid Fat globules in traumatic Fat Embolism
    Vestnik khirurgii imeni I. I. Grekova, 2020
    Co-Authors: Cherkasov Va, Litvinenko Sg, Rudakaov Ag
    Abstract:

    : The article is devoted to the problem of diagnosis and treatment of 28 patients with cranio-cerebral injury with posttraumatic Fat Embolism. In 15 of them Fat liquoroglobulia was diagnosed which is a reliable symptom of the cerebral form of Fat Embolism. The method of detection of Fat liquoroglobulia is described. A new method--liquorosorption--was used in treatment of patients with the cerebral form of Fat Embolism. A disturbance of the hematoencephalic barrier is thought by the authors to be possible in such Embolism.

  • The problem of posttraumatic Fat Embolism
    Vestnik khirurgii imeni I. I. Grekova, 2020
    Co-Authors: Cherkasov Va, Litvinenko Sg, Rudakov Ag
    Abstract:

    : The article is devoted to the problem of Fat Embolism. In 63 patients with combined and isolated traumas the maximum frequency of Fat Embolism was diagnosed in the investigation of blood serum from the femoral artery. It can be supposed that no isolated injury of the lesser circulation circuit can occur in Fat Embolism. An investigation of the venous-arterial difference of Fat globulemia has shown the main role of the so-called theory of shunting for Fat Embolism to be doubtful.

  • Diagnostics of traumatic Fat Embolism
    Journal of Clinical Gastroenterology, 2003
    Co-Authors: Cherkasov Va, Litvinenko Sg, Rudakov Ag
    Abstract:

    : The article deals with diagnosis and treatment of Fat Embolism concomitant with trauma. A new term is suggested, i.e. liqoroglobulism, which is concomitant with the cerebral form of Fat Embolism. The results of investigations of patients, who endured Fat Embolism, are presented. A new method is suggested for the treatment of Fat Embolism, i.e. a combination of hemosorption and liquosorption. A thesis on that the blood-brain barrier is damaged in the cerebral form of Fat Embolism is formulated.

Timothy C. Fabian - One of the best experts on this subject based on the ideXlab platform.

  • Unraveling the Fat Embolism syndrome
    The New England Journal of Medicine, 1993
    Co-Authors: Timothy C. Fabian
    Abstract:

    The Fat Embolism syndrome is a source of considerable morbidity after blunt trauma and is associated with a mortality of 10 to 20 percent. It has been recognized since the latter part of the 19th century1,2. Nonetheless, the pathophysiology of this syndrome remains incompletely understood, making the pursuit of strategies for its prevention and treatment difficult. The report on the Fat Embolism syndrome by Pell et al. in this issue of the Journal3 may provide an important direction for future efforts. In 90 percent of instances, the Fat Embolism syndrome occurs after blunt trauma complicated by long-bone fractures, . . .

  • unraveling the Fat Embolism syndrome
    The New England Journal of Medicine, 1993
    Co-Authors: Timothy C. Fabian
    Abstract:

    The Fat Embolism syndrome is a source of considerable morbidity after blunt trauma and is associated with a mortality of 10 to 20 percent. It has been recognized since the latter part of the 19th c...