The Experts below are selected from a list of 324 Experts worldwide ranked by ideXlab platform
Ami R. Zota - One of the best experts on this subject based on the ideXlab platform.
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Vaginal douching and racial/ethnic disparities in phthalates exposures among reProductive-aged women: National Health and Nutrition Examination Survey 2001–2004
Environmental Health, 2015Co-Authors: Francesca Branch, Tracey J. Woodruff, Susanna D. Mitro, Ami R. ZotaAbstract:Background: Diethyl phthalate (DEP) and di-n-butyl phthalate (DnBP) are industrial chemicals found in consumer Products that may increase risk of adverse health effects. Although use of personal care/beauty Products is known to contribute to phthalate exposure, no prior study has examined Feminine Hygiene Products as a potential phthalate source. In this study, we evaluate whether vaginal douching and other Feminine Hygiene Products increase exposure to phthalates among US reProductive-aged women. Methods: We conducted a cross-sectional study on 739 women (aged 20–49) from the National Health and Nutrition Examination Survey 2001–2004 to examine the association between self-reported use of Feminine Hygiene Products (tampons, sanitary napkins, vaginal douches, Feminine spray, Feminine powder, and Feminine wipes/towelettes) with urinary concentrations of monoethyl phthalate (MEP) and mono-n-butyl phthalate (MnBP), metabolites of DEP and DnBP, respectively. Results: A greater proportion of black women than white and Mexican American women reported use of vaginal douches, Feminine spray, Feminine powder, and wipes/towelettes in the past month whereas white women were more likely than other racial/ethnic groups to report use of tampons (p< 0.05). Douching in the past month was associated with higher concentrations of MEP but not MnBP. No other Feminine Hygiene Product was significantly associated with either MEP or MnBP. We observed a dose–response relationship between douching frequency and MEP concentrations (ptrend< 0.0001); frequent users (≥2 times/month) had 152.2 % (95 % confidence intervals (CI): (68.2 %, 278.3 %)) higher MEP concentrations than non-users. We also examined whether vaginal douching mediates the relationship between race/ethnicity and phthalates exposures. Black women had 48.4 % (95 % CI: 16.8 %, 88.6 %; p =0.0002) higher MEP levels than white women. Adjustment for douching attenuated this difference to 26.4 % (95 % CI:−0.9 %, 61.2 %; p =0.06). Mediation effects of douching were statistically significant for black-white differences (z= 3.71, p
Zota, Ami R - One of the best experts on this subject based on the ideXlab platform.
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Vaginal douching and racial/ethnic disparities in phthalates exposures among reProductive-aged women: National Health and Nutrition Examination Survey 2001-2004.
eScholarship University of California, 2015Co-Authors: Branch Francesca, Woodruff, Tracey J, Mitro, Susanna D, Zota, Ami RAbstract:BACKGROUND:Diethyl phthalate (DEP) and di-n-butyl phthalate (DnBP) are industrial chemicals found in consumer Products that may increase risk of adverse health effects. Although use of personal care/beauty Products is known to contribute to phthalate exposure, no prior study has examined Feminine Hygiene Products as a potential phthalate source. In this study, we evaluate whether vaginal douching and other Feminine Hygiene Products increase exposure to phthalates among US reProductive-aged women. METHODS:We conducted a cross-sectional study on 739 women (aged 20-49) from the National Health and Nutrition Examination Survey 2001-2004 to examine the association between self-reported use of Feminine Hygiene Products (tampons, sanitary napkins, vaginal douches, Feminine spray, Feminine powder, and Feminine wipes/towelettes) with urinary concentrations of monoethyl phthalate (MEP) and mono-n-butyl phthalate (MnBP), metabolites of DEP and DnBP, respectively. RESULTS:A greater proportion of black women than white and Mexican American women reported use of vaginal douches, Feminine spray, Feminine powder, and wipes/towelettes in the past month whereas white women were more likely than other racial/ethnic groups to report use of tampons (p < 0.05). Douching in the past month was associated with higher concentrations of MEP but not MnBP. No other Feminine Hygiene Product was significantly associated with either MEP or MnBP. We observed a dose-response relationship between douching frequency and MEP concentrations (p(trend) < 0.0001); frequent users (≥2 times/month) had 152.2% (95% confidence intervals (CI): (68.2%, 278.3%)) higher MEP concentrations than non-users. We also examined whether vaginal douching mediates the relationship between race/ethnicity and phthalates exposures. Black women had 48.4% (95% CI: 16.8%, 88.6%; p = 0.0002) higher MEP levels than white women. Adjustment for douching attenuated this difference to 26.4% (95% CI:-0.9%, 61.2%; p = 0.06). Mediation effects of douching were statistically significant for black-white differences (z = 3.71, p < 0.001) but not for differences between Mexican Americans and whites (z = 1.80, p = 0.07). CONCLUSIONS:Vaginal douching may increase exposure to DEP and contribute to racial/ethnic disparities in DEP exposure. The presence of environmental chemicals in vaginal douches warrants further examination
Younjoo An - One of the best experts on this subject based on the ideXlab platform.
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comparative study of Feminine Hygiene Product regulations in korea the european union and the united states
Regulatory Toxicology and Pharmacology, 2019Co-Authors: Jin Il Kwak, Younjoo AnAbstract:Abstract Recently, Korean consumers have experienced public health issues as a result of problematic Feminine Hygiene Products. Consumers and local civic groups have urged manufacturers and the Korean government to provide clear information based on comprehensive studies and strengthen related policies. In this study, we collected and compiled information on the relevant regulations and organizations in Korea, the European Union, and the United States to compare the management systems and legal status of Feminine Hygiene Products around the world. We confirmed that the definition of Feminine Hygiene Products is similar for Korea, the EU, and the US; however, they are categorized as quasi-drugs in Korea, general Products in the EU, and medical devices in US according to various regulations. Although we cannot completely prevent human exposure to chemicals in modern society, it is vital to establish a management system for the safe use and Production of Feminine Hygiene Products in a scientifically and legally sound manner. This research can contribute to the regulatory toxicology and risk assessment fields of Feminine Hygiene Product research.
Francesca Branch - One of the best experts on this subject based on the ideXlab platform.
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Vaginal douching and racial/ethnic disparities in phthalates exposures among reProductive-aged women: National Health and Nutrition Examination Survey 2001–2004
Environmental Health, 2015Co-Authors: Francesca Branch, Tracey J. Woodruff, Susanna D. Mitro, Ami R. ZotaAbstract:Background: Diethyl phthalate (DEP) and di-n-butyl phthalate (DnBP) are industrial chemicals found in consumer Products that may increase risk of adverse health effects. Although use of personal care/beauty Products is known to contribute to phthalate exposure, no prior study has examined Feminine Hygiene Products as a potential phthalate source. In this study, we evaluate whether vaginal douching and other Feminine Hygiene Products increase exposure to phthalates among US reProductive-aged women. Methods: We conducted a cross-sectional study on 739 women (aged 20–49) from the National Health and Nutrition Examination Survey 2001–2004 to examine the association between self-reported use of Feminine Hygiene Products (tampons, sanitary napkins, vaginal douches, Feminine spray, Feminine powder, and Feminine wipes/towelettes) with urinary concentrations of monoethyl phthalate (MEP) and mono-n-butyl phthalate (MnBP), metabolites of DEP and DnBP, respectively. Results: A greater proportion of black women than white and Mexican American women reported use of vaginal douches, Feminine spray, Feminine powder, and wipes/towelettes in the past month whereas white women were more likely than other racial/ethnic groups to report use of tampons (p< 0.05). Douching in the past month was associated with higher concentrations of MEP but not MnBP. No other Feminine Hygiene Product was significantly associated with either MEP or MnBP. We observed a dose–response relationship between douching frequency and MEP concentrations (ptrend< 0.0001); frequent users (≥2 times/month) had 152.2 % (95 % confidence intervals (CI): (68.2 %, 278.3 %)) higher MEP concentrations than non-users. We also examined whether vaginal douching mediates the relationship between race/ethnicity and phthalates exposures. Black women had 48.4 % (95 % CI: 16.8 %, 88.6 %; p =0.0002) higher MEP levels than white women. Adjustment for douching attenuated this difference to 26.4 % (95 % CI:−0.9 %, 61.2 %; p =0.06). Mediation effects of douching were statistically significant for black-white differences (z= 3.71, p
Branch Francesca - One of the best experts on this subject based on the ideXlab platform.
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Vaginal douching and racial/ethnic disparities in phthalates exposures among reProductive-aged women: National Health and Nutrition Examination Survey 2001-2004.
eScholarship University of California, 2015Co-Authors: Branch Francesca, Woodruff, Tracey J, Mitro, Susanna D, Zota, Ami RAbstract:BACKGROUND:Diethyl phthalate (DEP) and di-n-butyl phthalate (DnBP) are industrial chemicals found in consumer Products that may increase risk of adverse health effects. Although use of personal care/beauty Products is known to contribute to phthalate exposure, no prior study has examined Feminine Hygiene Products as a potential phthalate source. In this study, we evaluate whether vaginal douching and other Feminine Hygiene Products increase exposure to phthalates among US reProductive-aged women. METHODS:We conducted a cross-sectional study on 739 women (aged 20-49) from the National Health and Nutrition Examination Survey 2001-2004 to examine the association between self-reported use of Feminine Hygiene Products (tampons, sanitary napkins, vaginal douches, Feminine spray, Feminine powder, and Feminine wipes/towelettes) with urinary concentrations of monoethyl phthalate (MEP) and mono-n-butyl phthalate (MnBP), metabolites of DEP and DnBP, respectively. RESULTS:A greater proportion of black women than white and Mexican American women reported use of vaginal douches, Feminine spray, Feminine powder, and wipes/towelettes in the past month whereas white women were more likely than other racial/ethnic groups to report use of tampons (p < 0.05). Douching in the past month was associated with higher concentrations of MEP but not MnBP. No other Feminine Hygiene Product was significantly associated with either MEP or MnBP. We observed a dose-response relationship between douching frequency and MEP concentrations (p(trend) < 0.0001); frequent users (≥2 times/month) had 152.2% (95% confidence intervals (CI): (68.2%, 278.3%)) higher MEP concentrations than non-users. We also examined whether vaginal douching mediates the relationship between race/ethnicity and phthalates exposures. Black women had 48.4% (95% CI: 16.8%, 88.6%; p = 0.0002) higher MEP levels than white women. Adjustment for douching attenuated this difference to 26.4% (95% CI:-0.9%, 61.2%; p = 0.06). Mediation effects of douching were statistically significant for black-white differences (z = 3.71, p < 0.001) but not for differences between Mexican Americans and whites (z = 1.80, p = 0.07). CONCLUSIONS:Vaginal douching may increase exposure to DEP and contribute to racial/ethnic disparities in DEP exposure. The presence of environmental chemicals in vaginal douches warrants further examination
