The Experts below are selected from a list of 300 Experts worldwide ranked by ideXlab platform

N C Tarhan - One of the best experts on this subject based on the ideXlab platform.

  • unusual association of tethered cord Filum Terminale lipoma and myxopapillary ependymoma
    Spine, 2008
    Co-Authors: Fuldem Yildirim Donmez, Ceyla Basaran, Zeynep Guvenc, N C Tarhan
    Abstract:

    STUDY DESIGN: Case report. OBJECTIVE: We report a 67-year old man with a known Filum Terminale lipoma causing a tethered cord extending to the subcutaneous fat tissue and a newly diagnosed concomitant ependymoma, revealed on lumbar magnetic resonance imaging (MRI). SUMMARY OF BACKGROUND DATA: The coexistence of Filum Terminale lipoma and ependymoma is very rare. The underlying reason of this coexistence is still unknown. The patients with known filar lipoma causing a tethered cord can be underdiagnosed clinically even though new symptoms develop. METHODS: Case study with lumbar MRI. RESULTS: The patient was operated, and both of the ependymoma and Filum Terminale lipoma were removed. The pathologic examination was consistent with the MRI findings. Three months after surgery, the patient improved significantly. CONCLUSION: The coexistence of Filum Terminale lipoma and ependymoma is rare. Patients with relevant symptoms may be referred for an MRI study; however, especially patients with known filar lipomas causing tethered cord may be missed. Therefore, including these patients, a contrast-enhanced lumbar MRI must be performed to exclude any coexistence of Filum Terminale lipoma and ependymoma in the early course of the disease which can also help the surgeon in guiding the appropriate treatment.

Thomas G Luerssen - One of the best experts on this subject based on the ideXlab platform.

  • the effect of tethered cord release on coronal spinal balance in tight Filum Terminale
    Spine, 2011
    Co-Authors: Joshua J Chern, Robert C Dauser, William E Whitehead, Daniel J Curry, Thomas G Luerssen
    Abstract:

    STUDY DESIGN: A retrospective review of coronal spine balance after tethered cord release for children with tight Filum Terminale. OBJECTIVE: To understand the effects of untethering on coronal spine balance for these patients. SUMMARY OF BACKGROUND DATA: In patients with tight Filum Terminale, the spinal cord is tethered by a thickened Filum with a low conus medullaris but without other forms of spinal dysraphism. There have not been studies examining the effects of spinal cord untethering on coronal spinal alignment in children with tight Filum Terminale. METHODS: Forty-five consecutive pediatric patients with tight Filum Terminale who had undergone untethering were evaluated. Their presenting signs and symptoms, pre- and postsurgery imagings, and clinical courses were reviewed for scoliosis progression. RESULTS: Twenty-six girls and 19 boys underwent tethered cord release at a mean age of 4.5 years. The prevalence of coronal spinal malalignment, manifesting as scoliosis, before the untethering procedure was 31% (14 of 45). During the follow-up period, nine patients had coronal spinal alignment that worsened>10° (five patients eventually underwent surgical fusion), two patients had spinal alignment that improved, and five patients' curves stabilized after untethering surgery. Therefore, at the end of the follow-up period, 9 of 45 patients (20%) had worsened coronal spinal alignment. In the multivariate analysis, patients who presented with a Cobb angle greater than 35° were most likely to progress (P=0.002, odds ratio=21). There was no operative morbidity or mortality associated with scoliosis surgery. CONCLUSION: A significant number of children with tight Filum Terminale were found to present with scoliosis. In patients with less severe curves, tethered cord release may halt scoliosis progression.

Shane R Tubbs - One of the best experts on this subject based on the ideXlab platform.

  • the Filum Terminale
    2019
    Co-Authors: Erfanul Saker, Charlotte Wilson, Shane R Tubbs
    Abstract:

    The Filum Terminale has often been overlooked in the literature due to its historical lack of research on its true morphology. It is only recently that the true anatomy and pathological involvement of the Filum Terminale in the tethered cord syndrome have been elucidated.

  • the Filum Terminale internum and externum a comprehensive review
    Journal of Clinical Neuroscience, 2017
    Co-Authors: Erfanul Saker, Brandon Michael Henry, Krzysztof A Tomaszewski, Marios Loukas, Joe Iwanaga, Rod J Oskouian, Shane R Tubbs
    Abstract:

    Abstract Introduction: The Filum Terminale has oven been overlooked in the literature probably due to its small size and historical lack of research on its true morphology. However, this structure’s roll in the tethered cord syndrome has become more apparent. Therefore, the current comprehensive review seemed timely. Methods: Using standard search engines, the history, embryology, anatomy, pathology and surgery of the Filum Terminale were reviewed. Conclusions: It is only recently that the true anatomy and pathological involvement of the Filum Terminale in the tethered cord syndrome have been elucidated.

  • the Filum Terminale externum
    Journal of Neurosurgery, 2005
    Co-Authors: Shane R Tubbs, Randall Lee Murphy, David R Kelly, Robert Lott, George E Salter, Jerry W Oakes
    Abstract:

    Object The Filum Terminale externum (FTE) is the extradural component of the Filum Terminale internum and little attention has been dedicated to this structure in the literature. The authors theorized that the rare intrasacral ependymomas may originate from ependymal cell collections within the FTE. Methods To address this hypothesis, the FTE was dissected and analyzed histologically in 15 adult cadavers. None of the specimens was found to harbor ependymal or other glial cell collections. Conclusions The authors found previously undescribed smooth-muscle cells within the FTE. Furthermore, histological analysis identified adipose, nerve, bone, and cartilage cells.

Fuldem Yildirim Donmez - One of the best experts on this subject based on the ideXlab platform.

  • unusual association of tethered cord Filum Terminale lipoma and myxopapillary ependymoma
    Spine, 2008
    Co-Authors: Fuldem Yildirim Donmez, Ceyla Basaran, Zeynep Guvenc, N C Tarhan
    Abstract:

    STUDY DESIGN: Case report. OBJECTIVE: We report a 67-year old man with a known Filum Terminale lipoma causing a tethered cord extending to the subcutaneous fat tissue and a newly diagnosed concomitant ependymoma, revealed on lumbar magnetic resonance imaging (MRI). SUMMARY OF BACKGROUND DATA: The coexistence of Filum Terminale lipoma and ependymoma is very rare. The underlying reason of this coexistence is still unknown. The patients with known filar lipoma causing a tethered cord can be underdiagnosed clinically even though new symptoms develop. METHODS: Case study with lumbar MRI. RESULTS: The patient was operated, and both of the ependymoma and Filum Terminale lipoma were removed. The pathologic examination was consistent with the MRI findings. Three months after surgery, the patient improved significantly. CONCLUSION: The coexistence of Filum Terminale lipoma and ependymoma is rare. Patients with relevant symptoms may be referred for an MRI study; however, especially patients with known filar lipomas causing tethered cord may be missed. Therefore, including these patients, a contrast-enhanced lumbar MRI must be performed to exclude any coexistence of Filum Terminale lipoma and ependymoma in the early course of the disease which can also help the surgeon in guiding the appropriate treatment.

Csaba Boros - One of the best experts on this subject based on the ideXlab platform.

  • the caudal end of the rat spinal cord transformation to and ultrastructure of the Filum Terminale
    Brain Research, 2004
    Co-Authors: M Rethelyi, Erika Lukacsi, Csaba Boros
    Abstract:

    Contrary to the current belief, the spinal cord of the rat does not terminate with the conus terminalis (CT), but its basic components (central canal, gray matter, white matter) continue in the Filum Terminale (FT). Proceeding caudally in the conus terminalis, first the motoneuron cell column discontinues in the ventral horn. More caudally the dorsal horns separate from the intermediate zone, and discontinue. The ensuing Filum Terminale consists of the slit-like central canal lined by ciliated ependymal cells, the periventricular gray matter and the peripheral white matter. Uniform small size neurons and glial cells populate the gray matter. Ultrastructural analysis revealed various types of axodendritic and axosomatic synapses as well as fine unmyelinated axons. The white matter consists mainly of myelinated nerve fibers. The neuronal components of the Filum Terminale, if they occur also in the human spinal cord, should be involved in the diagnosis and treatment of various diseases, e.g. tethered spinal cord syndrome, vascular malformations and disraphysm.