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P. De Potter - One of the best experts on this subject based on the ideXlab platform.

  • fine needle Aspiration biopsy of suspected intraocular tumors the 1992 urwick lecture
    Ophthalmology, 1993
    Co-Authors: Jerry A. Shields, Carol L. Shields, Hormoz Ehya, Ralph C. Eagle, P. De Potter
    Abstract:

    Background: Fine-Needle Aspiration biopsy recently has been used as a diagnostic modality for selected intraocular tumors and simulating conditions. However, the value of Fine-Needle Aspiration biopsy for intraocular tumors previously has not been clarified. Methods: Transocular Fine-Needle Aspiration biopsy was performed on selected patients who had intraocular lesions that were suspected clinically to be neoplasms but in which there was diagnostic uncertainty based on noninvasive clinical evaluation. These cases were analyzed to determine accuracy, complications, and limitations of the technique. Results: Of 6500 patients referred to the Oncology Service for evaluation of possible intraocular tumor, transocular Fine-Needle Aspiration biopsy was used clinically in 159 cases (2.4%). It proved to be a reliable diagnostic method for intraocular malignancies such as uveal melanoma, uveal metastasis, retinoblastoma, lymphoma, and leukemia. In the 140 cases (88%) in which adequate cytologic material was obtained, the sensitivity rate was 100% and the specificity rate was 98%. In 19 cases where the cytologic material was too scant to render a diagnosis, the sensitivity rate was 84% and the specificity rate was 98%. The problem of insufficient material for cytologic diagnosis has been greatly minimized with the recent use af a 22-gauge needle. The main complication was localized intraocular hemorrhage. Retinal detachment and tumor recurrence have not been observed. Conclusions: Transocular Fine-Needle Aspiration biopsy is a safe and reliable diagnostic method for suspected intraocular tumors and inflammatory conditions in which noninvasive diagnostic modalities have failed to establish the diagnosis and in which cytologic verification of the diagnosis is necessary to institute appropriate treatment. Although the authors have had few complications with Fine-Needle Aspiration biopsy, the technique should be reserved for selected cases where the diagnosis has not been established by less-invasive diagnostic measures.

  • Fine-Needle Aspiration biopsy of suspected intraocular tumors
    International ophthalmology clinics, 1993
    Co-Authors: Jerry A. Shields, Carol L. Shields, Hormoz Ehya, Ralph C. Eagle, P. De Potter
    Abstract:

    Background: Fine-Needle Aspiration biopsy recently has been used as a diagnostic modality for selected intraocular tumors and simulating conditions. However, the value of Fine-Needle Aspiration biopsy for intraocular tumors previously has not been clarified. Methods: Transocular Fine-Needle Aspiration biopsy was performed on selected patients who had intraocular lesions that were suspected clinically to be neoplasms but in which there was diagnostic uncertainty based on noninvasive clinical evaluation. These cases were analyzed to determine accuracy, complications, and limitations of the technique. Results: Of 6500 patients referred to the Oncology Service for evaluation of possible intraocular tumor, transocular Fine-Needle Aspiration biopsy was used clinically in 159 cases (2.4%). It proved to be a reliable diagnostic method for intraocular malignancies such as uveal melanoma, uveal metastasis, retinoblastoma, lymphoma, and leukemia. In the 140 cases (88%) in which adequate cytologic material was obtained, the sensitivity rate was 100% and the specificity rate was 98%. In 19 cases where the cytologic material was too scant to render a diagnosis, the sensitivity rate was 84% and the specificity rate was 98%. The problem of insufficient material for cytologic diagnosis has been greatly minimized with the recent use af a 22-gauge needle. The main complication was localized intraocular hemorrhage. Retinal detachment and tumor recurrence have not been observed. Conclusions: Transocular Fine-Needle Aspiration biopsy is a safe and reliable diagnostic method for suspected intraocular tumors and inflammatory conditions in which noninvasive diagnostic modalities have failed to establish the diagnosis and in which cytologic verification of the diagnosis is necessary to institute appropriate treatment. Although the authors have had few complications with Fine-Needle Aspiration biopsy, the technique should be reserved for selected cases where the diagnosis has not been established by less-invasive diagnostic measures. Ophthalmology 1993;100:1677-1684

Yolanda C. Oertel - One of the best experts on this subject based on the ideXlab platform.

  • Thyroid Fine-Needle Aspiration.
    American journal of clinical pathology, 2009
    Co-Authors: Yolanda C. Oertel
    Abstract:

    This letter is in reference to the article by Borget et al1 in which the authors report an unsatisfactory rate of 27% for thyroidal Fine-Needle Aspirations (FNAs). Waisman2 and I agree on several issues. This is not surprising, considering that we are both “interventional pathologists.” Our FNA roots go to the Karolinska Hospital and Torsten Lowhagen’s influence. More recently, we were both members of the same subcommittee at the National Cancer Institute Thyroid Fine-Needle Aspiration State of the Science conference in …

  • Fine-Needle Aspiration of the Thyroid: Technique and Terminology
    Endocrinology and metabolism clinics of North America, 2007
    Co-Authors: Yolanda C. Oertel
    Abstract:

    Fine-Needle Aspiration of the thyroid is a relatively low-cost procedure that can provide an accurate diagnosis rapidly. Success of Fine-Needle Aspiration requires an adequate sample, obtained by mastering the technique. The literature emphasizes the importance of having an experienced cytopathologist interpreting the smears. The author believes that more emphasis has to be placed on mastering this deceptively simple technique. The author shares technical hints learned over 30 years.

Mohammed Kashani-sabet - One of the best experts on this subject based on the ideXlab platform.

  • Fine needle Aspiration in the diagnosis of metastatic melanoma
    Journal of The American Academy of Dermatology, 2000
    Co-Authors: Lori K.e. Rodrigues, Stanley P.l. Leong, Britt-marie Ljung, Richard W. Sagebiel, Nancy J. Burnside, James R. Miller, Mohammed Kashani-sabet
    Abstract:

    Abstract Background: Fine needle Aspiration is an accurate technique to diagnose metastatic melanoma. Few reports exist in the literature describing its usefulness in many patients with melanoma confirmed by open biopsy. Objective: The purpose of this study was to determine the utility and predictive value of fine needle Aspiration in patients with malignant melanoma who presented with lesions suspected to be metastatic. Methods: We retrospectively reviewed 99 cases of fine needle Aspiration and the corresponding histologic findings obtained by open biopsy in 82 patients. Results: Of the 99 cases, 86 were positive for melanoma, 12 were negative, and one was indeterminate. The positive predictive value of fine needle Aspiration was 99%. One patient had a false-positive diagnosis. Conclusion: Fine needle Aspiration is a rapid, accurate, and minimally invasive procedure that is useful in the diagnosis of metastatic melanoma. Patients with a positive aspirate of palpable regional nodes can proceed directly to surgery, bypassing the need for an open biopsy. (J Am Acad Dermatol 2000;42:735-40.)

  • Fine needle Aspiration in the diagnosis of metastatic melanoma.
    Journal of the American Academy of Dermatology, 2000
    Co-Authors: Lori K.e. Rodrigues, Stanley P.l. Leong, Britt-marie Ljung, Richard W. Sagebiel, James R. Miller, N Burnside, Mohammed Kashani-sabet
    Abstract:

    Fine needle Aspiration is an accurate technique to diagnose metastatic melanoma. Few reports exist in the literature describing its usefulness in many patients with melanoma confirmed by open biopsy. The purpose of this study was to determine the utility and predictive value of fine needle Aspiration in patients with malignant melanoma who presented with lesions suspected to be metastatic. We retrospectively reviewed 99 cases of fine needle Aspiration and the corresponding histologic findings obtained by open biopsy in 82 patients. Of the 99 cases, 86 were positive for melanoma, 12 were negative, and one was indeterminate. The positive predictive value of fine needle Aspiration was 99%. One patient had a false-positive diagnosis. Fine needle Aspiration is a rapid, accurate, and minimally invasive procedure that is useful in the diagnosis of metastatic melanoma. Patients with a positive aspirate of palpable regional nodes can proceed directly to surgery, bypassing the need for an open biopsy.

Perikala V. Kumar - One of the best experts on this subject based on the ideXlab platform.

  • Value Of Fine Needle Aspiration In Diagnosing AbdominalandRetroperitoneal Masses Of Children
    2007
    Co-Authors: B. Geramizadeh, Perikala V. Kumar, A. Azizi, H.r. Forootan, Alireza Rasekhi
    Abstract:

    The aim of this study was to evaluate the role of fine needle Aspiration cytology in the diagnosis of abdominal and retroperitoneal masses in children on this study. In 53 cases of childhood abdominal and retroperitoneal masses within a 4 year period (1998-2001) preoperative fine needle Aspiration was done under the guide of CT scan. 2 pathologists reviewed fine needle Aspiration smears. In all of the cases the gold standard for diagnosis was the tissue specimen, which showed 37 malignant, 2 benign neoplastic and 12 nonneoplastic diseases.This study showed that the sensitivity and specificity of fine needle Aspiration cytology for the diagnosis of malignancy and benignity (positive or negative for malignancy) is 97.2% and 81.2% respectively. It was 100% accurate for the diagnosis of cell type in neuroblastoma-ganglioneuroblastoma, hepatoblastoma and Wilm's tumor, 77% accurate for lymphoma and 57% for germ cell tumors. There was no complication in any of the cases after f! ine needle Aspiration. So fine needle Aspiration is a reliable and sensitive method for the preoperative diagnosis of malignant pediatric abdominal and retroperitoneal masses and we recommend doing FNA cytology as a routine method for the diagnosis of such cases.

  • Testicular fine needle Aspiration cytology in male infertility.
    Acta cytologica, 2006
    Co-Authors: Ali Amin, Ahmad Monabati, Alireza Tadayon, Seyed Yahya Attaran, Perikala V. Kumar
    Abstract:

    Objective To compare the accuracy of testicular fine needle Aspiration and biopsy for diagnostic and therapeutic purposes. Study Design A comparison of testicular fine needle Aspiration and biopsy was performed on 34 infertile men over a 2-year period. Results Concordance of the 2 tests was evident in 88% of cases. In discordant cases fine needle Aspiration yielded more than biopsy, considering the existence of secondary sperinatocytes and spermatids. Charcot-Bottcher crystalloids were frequently seen in the cytoplasm of Sertoli cells in normal and abnormal spermatogenesis. Conclusion Testicular fine needle Aspiration is a simple and cost-effective method of evaluating testicular pathology in male factor infertility. It may yield more diagnostic and therapeutic material than does biopsy.

Jerry A. Shields - One of the best experts on this subject based on the ideXlab platform.

  • fine needle Aspiration biopsy of suspected intraocular tumors the 1992 urwick lecture
    Ophthalmology, 1993
    Co-Authors: Jerry A. Shields, Carol L. Shields, Hormoz Ehya, Ralph C. Eagle, P. De Potter
    Abstract:

    Background: Fine-Needle Aspiration biopsy recently has been used as a diagnostic modality for selected intraocular tumors and simulating conditions. However, the value of Fine-Needle Aspiration biopsy for intraocular tumors previously has not been clarified. Methods: Transocular Fine-Needle Aspiration biopsy was performed on selected patients who had intraocular lesions that were suspected clinically to be neoplasms but in which there was diagnostic uncertainty based on noninvasive clinical evaluation. These cases were analyzed to determine accuracy, complications, and limitations of the technique. Results: Of 6500 patients referred to the Oncology Service for evaluation of possible intraocular tumor, transocular Fine-Needle Aspiration biopsy was used clinically in 159 cases (2.4%). It proved to be a reliable diagnostic method for intraocular malignancies such as uveal melanoma, uveal metastasis, retinoblastoma, lymphoma, and leukemia. In the 140 cases (88%) in which adequate cytologic material was obtained, the sensitivity rate was 100% and the specificity rate was 98%. In 19 cases where the cytologic material was too scant to render a diagnosis, the sensitivity rate was 84% and the specificity rate was 98%. The problem of insufficient material for cytologic diagnosis has been greatly minimized with the recent use af a 22-gauge needle. The main complication was localized intraocular hemorrhage. Retinal detachment and tumor recurrence have not been observed. Conclusions: Transocular Fine-Needle Aspiration biopsy is a safe and reliable diagnostic method for suspected intraocular tumors and inflammatory conditions in which noninvasive diagnostic modalities have failed to establish the diagnosis and in which cytologic verification of the diagnosis is necessary to institute appropriate treatment. Although the authors have had few complications with Fine-Needle Aspiration biopsy, the technique should be reserved for selected cases where the diagnosis has not been established by less-invasive diagnostic measures.

  • Fine-Needle Aspiration biopsy of suspected intraocular tumors
    International ophthalmology clinics, 1993
    Co-Authors: Jerry A. Shields, Carol L. Shields, Hormoz Ehya, Ralph C. Eagle, P. De Potter
    Abstract:

    Background: Fine-Needle Aspiration biopsy recently has been used as a diagnostic modality for selected intraocular tumors and simulating conditions. However, the value of Fine-Needle Aspiration biopsy for intraocular tumors previously has not been clarified. Methods: Transocular Fine-Needle Aspiration biopsy was performed on selected patients who had intraocular lesions that were suspected clinically to be neoplasms but in which there was diagnostic uncertainty based on noninvasive clinical evaluation. These cases were analyzed to determine accuracy, complications, and limitations of the technique. Results: Of 6500 patients referred to the Oncology Service for evaluation of possible intraocular tumor, transocular Fine-Needle Aspiration biopsy was used clinically in 159 cases (2.4%). It proved to be a reliable diagnostic method for intraocular malignancies such as uveal melanoma, uveal metastasis, retinoblastoma, lymphoma, and leukemia. In the 140 cases (88%) in which adequate cytologic material was obtained, the sensitivity rate was 100% and the specificity rate was 98%. In 19 cases where the cytologic material was too scant to render a diagnosis, the sensitivity rate was 84% and the specificity rate was 98%. The problem of insufficient material for cytologic diagnosis has been greatly minimized with the recent use af a 22-gauge needle. The main complication was localized intraocular hemorrhage. Retinal detachment and tumor recurrence have not been observed. Conclusions: Transocular Fine-Needle Aspiration biopsy is a safe and reliable diagnostic method for suspected intraocular tumors and inflammatory conditions in which noninvasive diagnostic modalities have failed to establish the diagnosis and in which cytologic verification of the diagnosis is necessary to institute appropriate treatment. Although the authors have had few complications with Fine-Needle Aspiration biopsy, the technique should be reserved for selected cases where the diagnosis has not been established by less-invasive diagnostic measures. Ophthalmology 1993;100:1677-1684