Fox Fordyce Disease

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Stephanie F Marschall - One of the best experts on this subject based on the ideXlab platform.

  • treatment of Fox Fordyce Disease with liposuction assisted curettage
    2006
    Co-Authors: Stephanie F Marschall, Michael A Marschall, Mireille K Chae
    Abstract:

    FoxFordyce Disease is a rare, chronic, pruritic disorder characterized by small perifollicular papules localized to the apocrine gland-bearing regions of the skin. The Disease affects the apocrine-bearing areas of the skin. The authors discuss the various therapies available such as creams, medication, ultraviolet light, and surgical procedures. A case is reported of treatment with liposuction-assisted curettage resulting in reduced number of papules and no further need of corticosteroid cream.

  • axillary Fox Fordyce Disease treated with liposuction assisted curettage
    2002
    Co-Authors: Mireille K Chae, Michael A Marschall, Stephanie F Marschall
    Abstract:

    A 33-year-old African American woman presented with a long history of extremely pruritic, burning lesions in the axillae, on the breasts, and in the inguinal area. The eruption first began at age 15 years, with flares following pregnancy. On physical examination, the patient was noted to have numerous discrete, skin-colored papules in the axillae, around the areolae, and in the inguinal area (Figure 1). Biopsy results of one of these lesions were consistent with a diagnosis of Fox-Fordyce Disease or apocrine miliaria. Treatment with oral contraceptives was started with minimal improvement. Oral antihistamines were ineffective in controlling the pruritus. Topical 0.025% tretinoin cream and clindamycin in propylene glycol solution, each used separately, did not improve her symptoms and were discontinued due to irritation. Topical corticosteroids helped to relieve the pruritus and the burning sensation.

Mireille K Chae - One of the best experts on this subject based on the ideXlab platform.

  • treatment of Fox Fordyce Disease with liposuction assisted curettage
    2006
    Co-Authors: Stephanie F Marschall, Michael A Marschall, Mireille K Chae
    Abstract:

    FoxFordyce Disease is a rare, chronic, pruritic disorder characterized by small perifollicular papules localized to the apocrine gland-bearing regions of the skin. The Disease affects the apocrine-bearing areas of the skin. The authors discuss the various therapies available such as creams, medication, ultraviolet light, and surgical procedures. A case is reported of treatment with liposuction-assisted curettage resulting in reduced number of papules and no further need of corticosteroid cream.

  • axillary Fox Fordyce Disease treated with liposuction assisted curettage
    2002
    Co-Authors: Mireille K Chae, Michael A Marschall, Stephanie F Marschall
    Abstract:

    A 33-year-old African American woman presented with a long history of extremely pruritic, burning lesions in the axillae, on the breasts, and in the inguinal area. The eruption first began at age 15 years, with flares following pregnancy. On physical examination, the patient was noted to have numerous discrete, skin-colored papules in the axillae, around the areolae, and in the inguinal area (Figure 1). Biopsy results of one of these lesions were consistent with a diagnosis of Fox-Fordyce Disease or apocrine miliaria. Treatment with oral contraceptives was started with minimal improvement. Oral antihistamines were ineffective in controlling the pruritus. Topical 0.025% tretinoin cream and clindamycin in propylene glycol solution, each used separately, did not improve her symptoms and were discontinued due to irritation. Topical corticosteroids helped to relieve the pruritus and the burning sensation.

El C Habr - One of the best experts on this subject based on the ideXlab platform.

  • Fox Fordyce Disease an under diagnosed adverse event of laser hair removal
    2016
    Co-Authors: Rita Sammour, Selim Nasser, N Debahy, El C Habr
    Abstract:

    Background FoxFordyce Disease (FFD) is a rare chronic inflammatory skin Disease of the apocrine glands, mainly affecting post-pubertal women. It involves apocrine gland-bearing areas including the axilla, areola, anogenital area and umbilicus. FFD induced by laser hair removal is a newly reported entity of unknown pathogenesis. To the best of our knowledge, there are only four reported cases in the literature describing a total of four patients. Objectives We are reporting the first case series of laser-induced FFD with a histopathological and clinical evaluation of the reported cases. Methods A review of the available literature to date about laser-induced FFD was performed. Clinical and histopathological features were reviewed. Results In our case series, the clinical and histological appearance of FFD following laser hair removal is similar to that of classic FFD. Exacerbating factors were present in two patients, and were similar to that of classic FFD. The main histopathological features included dilatation of the follicular infundibulum, follicular hyperkeratosis, dyskeratosis in the follicular infundibulum, periductal lymphohistiocytic infiltrate and perifollicular fibrosis. Two of the four reported cases as well as one of our patients had no perifollicular xanthomatous inflammation, a hallmark feature of classic FFD. Mast cells were absent in all reported cases, as well as in our patients. Conclusion: We believe that laser-induced FFD is under-diagnosed as a newly reported adverse event of laser hair removal. It is clinically and histopathologically similar to classic FFD.

Michael A Marschall - One of the best experts on this subject based on the ideXlab platform.

  • treatment of Fox Fordyce Disease with liposuction assisted curettage
    2006
    Co-Authors: Stephanie F Marschall, Michael A Marschall, Mireille K Chae
    Abstract:

    FoxFordyce Disease is a rare, chronic, pruritic disorder characterized by small perifollicular papules localized to the apocrine gland-bearing regions of the skin. The Disease affects the apocrine-bearing areas of the skin. The authors discuss the various therapies available such as creams, medication, ultraviolet light, and surgical procedures. A case is reported of treatment with liposuction-assisted curettage resulting in reduced number of papules and no further need of corticosteroid cream.

  • axillary Fox Fordyce Disease treated with liposuction assisted curettage
    2002
    Co-Authors: Mireille K Chae, Michael A Marschall, Stephanie F Marschall
    Abstract:

    A 33-year-old African American woman presented with a long history of extremely pruritic, burning lesions in the axillae, on the breasts, and in the inguinal area. The eruption first began at age 15 years, with flares following pregnancy. On physical examination, the patient was noted to have numerous discrete, skin-colored papules in the axillae, around the areolae, and in the inguinal area (Figure 1). Biopsy results of one of these lesions were consistent with a diagnosis of Fox-Fordyce Disease or apocrine miliaria. Treatment with oral contraceptives was started with minimal improvement. Oral antihistamines were ineffective in controlling the pruritus. Topical 0.025% tretinoin cream and clindamycin in propylene glycol solution, each used separately, did not improve her symptoms and were discontinued due to irritation. Topical corticosteroids helped to relieve the pruritus and the burning sensation.

G Obeid - One of the best experts on this subject based on the ideXlab platform.

  • Fox Fordyce like Disease following laser hair removal appearing on all treated areas
    2013
    Co-Authors: Josiane Helou, Ismael Maatouk, Roy Moutran, G Obeid
    Abstract:

    Fox-Fordyce Disease is an uncommon inflamma- tory Disease of the apocrine sweat glands. Two recent reports indicated laser hair removal as a novel cause of axillary Fox-Fordyce Disease. We report the first case of Fox-Fordyce Disease developing in women after completing treatment with a depilatory hair laser appearing in the axillae, umbilicus, and pubis. We describe a case of Fox-Fordyce Disease that developed in a 27-year-old woman 3 months after she had completed two LightSheer Diode laser treat- ments of her axilla, periumbilical region, and bikini area. Clinical and histopathological changes are as well detailed. Laser therapy induces damage to follicular infundibulum, resulting in altered maturation of keratinocytes which led to keratin plugging causing the common pathologic features in Fox-Fordyce Disease. Differences in the physiologic features of the anatomic sites, in the susceptibility to laser-induced injury among these areas, or additional factors may contrib- ute to Fox-Fordyce Disease.