The Experts below are selected from a list of 198363 Experts worldwide ranked by ideXlab platform
Xuejun Zhang - One of the best experts on this subject based on the ideXlab platform.
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theranostic metal organic Framework Core shell composites for magnetic resonance imaging and drug delivery
Chemical Science, 2016Co-Authors: Huai-xin Zhao, Quan Zou, Shao-kai Sun, Xuejun ZhangAbstract:Metal–organic Frameworks (MOFs) have shown great potential in designing theranostic probes for cancer diagnosis and therapy due to their unique properties, including versatile structures and composition, tunable particle and pore size, enormous porosity, high surface area, and intrinsic biodegradability. In this study, we demonstrate novel MOF-based theranostic Fe3O4@UiO-66 Core–shell composites constructed by in situ growth of a UiO-66 MOF shell on a Fe3O4 Core for simultaneous drug delivery and magnetic resonance (MR) imaging. In the composites, the UiO-66 shell is devoted for encapsulating the drug, whereas the Fe3O4 Core serves as a MR contrast agent. The Fe3O4@UiO-66 Core–shell composites show good biocompatibility, high drug loading capacity, sustained drug release, and outstanding MR imaging capability, as well as effective chemotherapeutic efficacy, demonstrating the feasibility of designing theranostic Fe3O4@UiO-66 Core–shell composites for cancer diagnosis and therapy.
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Theranostic metal–organic Framework Core–shell composites for magnetic resonance imaging and drug delivery
Chemical science, 2016Co-Authors: Huai-xin Zhao, Quan Zou, Shao-kai Sun, Xuejun ZhangAbstract:Metal–organic Frameworks (MOFs) have shown great potential in designing theranostic probes for cancer diagnosis and therapy due to their unique properties, including versatile structures and composition, tunable particle and pore size, enormous porosity, high surface area, and intrinsic biodegradability. In this study, we demonstrate novel MOF-based theranostic Fe3O4@UiO-66 Core–shell composites constructed by in situ growth of a UiO-66 MOF shell on a Fe3O4 Core for simultaneous drug delivery and magnetic resonance (MR) imaging. In the composites, the UiO-66 shell is devoted for encapsulating the drug, whereas the Fe3O4 Core serves as a MR contrast agent. The Fe3O4@UiO-66 Core–shell composites show good biocompatibility, high drug loading capacity, sustained drug release, and outstanding MR imaging capability, as well as effective chemotherapeutic efficacy, demonstrating the feasibility of designing theranostic Fe3O4@UiO-66 Core–shell composites for cancer diagnosis and therapy.
Xiaochun Wan - One of the best experts on this subject based on the ideXlab platform.
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highly selective removal of hg2 and pb2 by thiol functionalized fe3o4 metal organic Framework Core shell magnetic microspheres
Applied Surface Science, 2017Co-Authors: Jing Jiang, Jing Liang, Xiaochun WanAbstract:Abstract In this work, we report a novel type of thiol-functionalized magnetic Core-shell metal-organic Framework (MOF) microspheres that can be potentially used for selective removal of Hg 2+ and Pb 2+ in the presence of other background ions from wastewater. The monodisperse Fe 3 O 4 @Cu 3 (btc) 2 Core-shell magnetic microspheres have been fabricated by a versatile step-by-step assembly strategy. Further, the thiol-functionalized Fe 3 O 4 @Cu 3 (btc) 2 magnetic microspheres were successfully synthesized by utilizing a facile postsynthetic strategy. Significantly, the thiol-functionalized Fe 3 O 4 @Cu 3 (btc) 2 magnetic microspheres exhibit remarkably selective adsorption affinity for Hg 2+ ( K d = 5.98 × 10 4 mL g −1 ) and Pb 2+ ( K d = 1.23 × 10 4 mL g −1 ), while a weaker binding affinity occurred for the other background ions such as Ni 2+ , Na + , Mg 2+ , Ca 2+ , Zn 2+ and Cd 2+ . The adsorption kinetics follow the pseudo-second-order rate equation and with an almost complete removal of Hg 2+ and Pb 2+ from the mixed heavy metal ions wastewater (0.5 mM) within 120 min. Moreover, this adsorbent can be easily recycled because of the presence of the magnetic Fe 3 O 4 Core. This work provides a promising functionalized porous magnetic Fe 3 O 4 @MOF-based adsorbent with easy recycling property for the selective removal of heavy metal ions from wastewater.
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Highly selective removal of Hg2+ and Pb2+ by thiol-functionalized Fe3O4@metal-organic Framework Core-shell magnetic microspheres
Applied Surface Science, 2017Co-Authors: Jing Jiang, Jing Liang, Xiaochun WanAbstract:Abstract In this work, we report a novel type of thiol-functionalized magnetic Core-shell metal-organic Framework (MOF) microspheres that can be potentially used for selective removal of Hg 2+ and Pb 2+ in the presence of other background ions from wastewater. The monodisperse Fe 3 O 4 @Cu 3 (btc) 2 Core-shell magnetic microspheres have been fabricated by a versatile step-by-step assembly strategy. Further, the thiol-functionalized Fe 3 O 4 @Cu 3 (btc) 2 magnetic microspheres were successfully synthesized by utilizing a facile postsynthetic strategy. Significantly, the thiol-functionalized Fe 3 O 4 @Cu 3 (btc) 2 magnetic microspheres exhibit remarkably selective adsorption affinity for Hg 2+ ( K d = 5.98 × 10 4 mL g −1 ) and Pb 2+ ( K d = 1.23 × 10 4 mL g −1 ), while a weaker binding affinity occurred for the other background ions such as Ni 2+ , Na + , Mg 2+ , Ca 2+ , Zn 2+ and Cd 2+ . The adsorption kinetics follow the pseudo-second-order rate equation and with an almost complete removal of Hg 2+ and Pb 2+ from the mixed heavy metal ions wastewater (0.5 mM) within 120 min. Moreover, this adsorbent can be easily recycled because of the presence of the magnetic Fe 3 O 4 Core. This work provides a promising functionalized porous magnetic Fe 3 O 4 @MOF-based adsorbent with easy recycling property for the selective removal of heavy metal ions from wastewater.
Adam Freeman - One of the best experts on this subject based on the ideXlab platform.
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Advanced Web Service Features
Pro ASP.NET Core 3, 2020Co-Authors: Adam FreemanAbstract:In this chapter, I describe advanced features that can be used to create RESTful web services. I explain how to deal with related data in Entity Framework Core queries, how to add support for the HTTP PATCH method, how to use content negations, and how to use OpenAPI to describe your web services. Table 20-1 puts this chapter in context.
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Creating Form Applications
Pro ASP.NET Core 3, 2020Co-Authors: Adam FreemanAbstract:The previous chapters have focused on individual features that deal with one aspect of HTML forms, and it can sometimes be difficult to see how they fit together to perform common tasks. In this chapter, I go through the process of creating controllers, views, and Razor Pages that support an application with create, read, update, and delete (CRUD) functionality. There are no new features described in this chapter, and the objective is to demonstrate how features such as tag helpers, model binding, and model validation can be used in conjunction with Entity Framework Core.
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Blazor Forms and Data
Pro ASP.NET Core 3, 2020Co-Authors: Adam FreemanAbstract:In this chapter, I describe the features that Blazor provides for dealing with HTML forms, including support for data validation. I describe the built-in components that Blazor provides and show you how they are used. In this chapter, I also explain how the Blazor model can cause unexpected results with Entity Framework Core and show you how to address these issues. I finish the chapter by creating a simple form application for creating, reading, updating, and deleting data (the CRUD operations) and explain how to extend the Blazor form features to improve the user’s experience. Table 36-1 puts the Blazor form features in context.
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Working with Entity Framework Core
Pro Entity Framework Core 2 for ASP.NET Core MVC, 2018Co-Authors: Adam FreemanAbstract:In this chapter, I explain how Entity Framework Core is applied to an ASP.NET Core MVC project, starting with the addition of NuGet packages and working through the creation of a basic data model, a database schema, and the infrastructure to use it. The project created in this chapter sets the foundation for those that follow, which add Entity Framework Core features. Table 11-1 summarizes the chapter.
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Your First Entity Framework Core Application
Pro Entity Framework Core 2 for ASP.NET Core MVC, 2018Co-Authors: Adam FreemanAbstract:The best way to get started with Entity Framework Core is to jump right in and use it. In this chapter, I create a simple application using Entity Framework Core and ASP.NET Core MVC so you can see how everything fits together. To keep the example simple, I skip over some of the details that are described in later chapters.
Huai-xin Zhao - One of the best experts on this subject based on the ideXlab platform.
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theranostic metal organic Framework Core shell composites for magnetic resonance imaging and drug delivery
Chemical Science, 2016Co-Authors: Huai-xin Zhao, Quan Zou, Shao-kai Sun, Xuejun ZhangAbstract:Metal–organic Frameworks (MOFs) have shown great potential in designing theranostic probes for cancer diagnosis and therapy due to their unique properties, including versatile structures and composition, tunable particle and pore size, enormous porosity, high surface area, and intrinsic biodegradability. In this study, we demonstrate novel MOF-based theranostic Fe3O4@UiO-66 Core–shell composites constructed by in situ growth of a UiO-66 MOF shell on a Fe3O4 Core for simultaneous drug delivery and magnetic resonance (MR) imaging. In the composites, the UiO-66 shell is devoted for encapsulating the drug, whereas the Fe3O4 Core serves as a MR contrast agent. The Fe3O4@UiO-66 Core–shell composites show good biocompatibility, high drug loading capacity, sustained drug release, and outstanding MR imaging capability, as well as effective chemotherapeutic efficacy, demonstrating the feasibility of designing theranostic Fe3O4@UiO-66 Core–shell composites for cancer diagnosis and therapy.
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Theranostic metal–organic Framework Core–shell composites for magnetic resonance imaging and drug delivery
Chemical science, 2016Co-Authors: Huai-xin Zhao, Quan Zou, Shao-kai Sun, Xuejun ZhangAbstract:Metal–organic Frameworks (MOFs) have shown great potential in designing theranostic probes for cancer diagnosis and therapy due to their unique properties, including versatile structures and composition, tunable particle and pore size, enormous porosity, high surface area, and intrinsic biodegradability. In this study, we demonstrate novel MOF-based theranostic Fe3O4@UiO-66 Core–shell composites constructed by in situ growth of a UiO-66 MOF shell on a Fe3O4 Core for simultaneous drug delivery and magnetic resonance (MR) imaging. In the composites, the UiO-66 shell is devoted for encapsulating the drug, whereas the Fe3O4 Core serves as a MR contrast agent. The Fe3O4@UiO-66 Core–shell composites show good biocompatibility, high drug loading capacity, sustained drug release, and outstanding MR imaging capability, as well as effective chemotherapeutic efficacy, demonstrating the feasibility of designing theranostic Fe3O4@UiO-66 Core–shell composites for cancer diagnosis and therapy.
Jing Jiang - One of the best experts on this subject based on the ideXlab platform.
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highly selective removal of hg2 and pb2 by thiol functionalized fe3o4 metal organic Framework Core shell magnetic microspheres
Applied Surface Science, 2017Co-Authors: Jing Jiang, Jing Liang, Xiaochun WanAbstract:Abstract In this work, we report a novel type of thiol-functionalized magnetic Core-shell metal-organic Framework (MOF) microspheres that can be potentially used for selective removal of Hg 2+ and Pb 2+ in the presence of other background ions from wastewater. The monodisperse Fe 3 O 4 @Cu 3 (btc) 2 Core-shell magnetic microspheres have been fabricated by a versatile step-by-step assembly strategy. Further, the thiol-functionalized Fe 3 O 4 @Cu 3 (btc) 2 magnetic microspheres were successfully synthesized by utilizing a facile postsynthetic strategy. Significantly, the thiol-functionalized Fe 3 O 4 @Cu 3 (btc) 2 magnetic microspheres exhibit remarkably selective adsorption affinity for Hg 2+ ( K d = 5.98 × 10 4 mL g −1 ) and Pb 2+ ( K d = 1.23 × 10 4 mL g −1 ), while a weaker binding affinity occurred for the other background ions such as Ni 2+ , Na + , Mg 2+ , Ca 2+ , Zn 2+ and Cd 2+ . The adsorption kinetics follow the pseudo-second-order rate equation and with an almost complete removal of Hg 2+ and Pb 2+ from the mixed heavy metal ions wastewater (0.5 mM) within 120 min. Moreover, this adsorbent can be easily recycled because of the presence of the magnetic Fe 3 O 4 Core. This work provides a promising functionalized porous magnetic Fe 3 O 4 @MOF-based adsorbent with easy recycling property for the selective removal of heavy metal ions from wastewater.
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Highly selective removal of Hg2+ and Pb2+ by thiol-functionalized Fe3O4@metal-organic Framework Core-shell magnetic microspheres
Applied Surface Science, 2017Co-Authors: Jing Jiang, Jing Liang, Xiaochun WanAbstract:Abstract In this work, we report a novel type of thiol-functionalized magnetic Core-shell metal-organic Framework (MOF) microspheres that can be potentially used for selective removal of Hg 2+ and Pb 2+ in the presence of other background ions from wastewater. The monodisperse Fe 3 O 4 @Cu 3 (btc) 2 Core-shell magnetic microspheres have been fabricated by a versatile step-by-step assembly strategy. Further, the thiol-functionalized Fe 3 O 4 @Cu 3 (btc) 2 magnetic microspheres were successfully synthesized by utilizing a facile postsynthetic strategy. Significantly, the thiol-functionalized Fe 3 O 4 @Cu 3 (btc) 2 magnetic microspheres exhibit remarkably selective adsorption affinity for Hg 2+ ( K d = 5.98 × 10 4 mL g −1 ) and Pb 2+ ( K d = 1.23 × 10 4 mL g −1 ), while a weaker binding affinity occurred for the other background ions such as Ni 2+ , Na + , Mg 2+ , Ca 2+ , Zn 2+ and Cd 2+ . The adsorption kinetics follow the pseudo-second-order rate equation and with an almost complete removal of Hg 2+ and Pb 2+ from the mixed heavy metal ions wastewater (0.5 mM) within 120 min. Moreover, this adsorbent can be easily recycled because of the presence of the magnetic Fe 3 O 4 Core. This work provides a promising functionalized porous magnetic Fe 3 O 4 @MOF-based adsorbent with easy recycling property for the selective removal of heavy metal ions from wastewater.
