The Experts below are selected from a list of 282 Experts worldwide ranked by ideXlab platform
Norio Shibata - One of the best experts on this subject based on the ideXlab platform.
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Remote Anionic Fries Rearrangement of Sulfonates: Regioselective Synthesis of Indole Triflones.
ChemInform, 2013Co-Authors: Misaki Taniguchi, Guokai Liu, Etsuko Tokunaga, Ayaka Azuma, Norio ShibataAbstract:An unusual NaH-mediated 1,5-thia-Fries Rearrangement providing the title compounds is presented.
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Remote anionic Fries Rearrangement of sulfonates: regioselective synthesis of indole triflones.
Organic letters, 2013Co-Authors: Misaki Taniguchi, Guokai Liu, Etsuko Tokunaga, Ayaka Azuma, Norio ShibataAbstract:An unusual NaH-mediated remote anionic 1,5-thia-Fries Rearrangement reaction was developed. This method provides an efficient approach for the regioselective synthesis of not only 2-(2-hydroxyphenyl)-3-indole triflones but also related 3-sulfonylindoles.
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Regioselective Synthesis of Heteroaryl Triflones by LDA (Lithium Diisopropylamide)-Mediated Anionic Thia-Fries Rearrangement
Organic letters, 2012Co-Authors: Xin Wang, Guokai Liu, Etsuko Tokunaga, Norio ShibataAbstract:Novel heteroaryl triflones including oxindole, pyrazolone, pyridine, and quinoline derivatives have been regioselectively synthesized by LDA-mediated thia-Fries Rearrangement for the first time. These reactions are also the first examples of the application of anionic thia-Fries Rearrangement in heteroaromatic compounds.
Mohinder P. Mahajan - One of the best experts on this subject based on the ideXlab platform.
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tandem michael addition Fries Rearrangement of sorbylanilides a convenient one pot synthesis of novel benzo b azocin 6 ones
Tetrahedron Letters, 2012Co-Authors: Amit Anand, Pardeep Singh, Vishu Mehra, Vipan Kumar, Mohinder P. MahajanAbstract:Abstract The Letter pertains to an unprecedented tandem Michael addition–Fries Rearrangement of sorbyl anilides resulting in a convenient one pot synthesis of novel benzo[ b ]azocin-6-ones. The reaction is thought to proceed via a δ-lactam intermediate, earlier considered un-reactive for Fries Rearrangement. The proposed mechanism was further supported by examining the reactions of α,β-unsaturated anilides. Their inability to undergo any transformation under similar reaction conditions, especially the Fries–Michael Rearrangement, indirectly validated the mechanism.
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Tandem Michael addition–Fries Rearrangement of sorbylanilides: a convenient one pot synthesis of novel benzo[b]azocin-6-ones
Tetrahedron Letters, 2012Co-Authors: Amit Anand, Pardeep Singh, Vishu Mehra, Amandeep, Vipan Kumar, Mohinder P. MahajanAbstract:Abstract The Letter pertains to an unprecedented tandem Michael addition–Fries Rearrangement of sorbyl anilides resulting in a convenient one pot synthesis of novel benzo[ b ]azocin-6-ones. The reaction is thought to proceed via a δ-lactam intermediate, earlier considered un-reactive for Fries Rearrangement. The proposed mechanism was further supported by examining the reactions of α,β-unsaturated anilides. Their inability to undergo any transformation under similar reaction conditions, especially the Fries–Michael Rearrangement, indirectly validated the mechanism.
Amit Anand - One of the best experts on this subject based on the ideXlab platform.
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tandem michael addition Fries Rearrangement of sorbylanilides a convenient one pot synthesis of novel benzo b azocin 6 ones
Tetrahedron Letters, 2012Co-Authors: Amit Anand, Pardeep Singh, Vishu Mehra, Vipan Kumar, Mohinder P. MahajanAbstract:Abstract The Letter pertains to an unprecedented tandem Michael addition–Fries Rearrangement of sorbyl anilides resulting in a convenient one pot synthesis of novel benzo[ b ]azocin-6-ones. The reaction is thought to proceed via a δ-lactam intermediate, earlier considered un-reactive for Fries Rearrangement. The proposed mechanism was further supported by examining the reactions of α,β-unsaturated anilides. Their inability to undergo any transformation under similar reaction conditions, especially the Fries–Michael Rearrangement, indirectly validated the mechanism.
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Tandem Michael addition–Fries Rearrangement of sorbylanilides: a convenient one pot synthesis of novel benzo[b]azocin-6-ones
Tetrahedron Letters, 2012Co-Authors: Amit Anand, Pardeep Singh, Vishu Mehra, Amandeep, Vipan Kumar, Mohinder P. MahajanAbstract:Abstract The Letter pertains to an unprecedented tandem Michael addition–Fries Rearrangement of sorbyl anilides resulting in a convenient one pot synthesis of novel benzo[ b ]azocin-6-ones. The reaction is thought to proceed via a δ-lactam intermediate, earlier considered un-reactive for Fries Rearrangement. The proposed mechanism was further supported by examining the reactions of α,β-unsaturated anilides. Their inability to undergo any transformation under similar reaction conditions, especially the Fries–Michael Rearrangement, indirectly validated the mechanism.
Rong-jie Chein - One of the best experts on this subject based on the ideXlab platform.
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from carbamate to chalcone consecutive anionic Fries Rearrangement anionic si c alkyl Rearrangement and claisen schmidt condensation
Organic Letters, 2018Co-Authors: Singam Naveen Kumar, Suhas Ravindra Bavikar, Chebolu Naga Sesha Sai Pavan Kumar, Rong-jie CheinAbstract:A highly efficient one-pot procedure was developed for the synthesis of various 2′-hydroxychalcones from phenyl diethylcarbamate, featuring consecutive Snieckus–Fries Rearrangement, anionic Si → C alkyl Rearrangement, and Claisen–Schmidt condensation in a single operation. The applicability of this protocol was demonstrated by the highly efficient synthesis of the anti-inflammatory natural product lonchocarpin. The mechanism insight is also provided.
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From Carbamate to Chalcone: Consecutive Anionic Fries Rearrangement, Anionic Si → C Alkyl Rearrangement, and Claisen–Schmidt Condensation
2018Co-Authors: Singam Naveen Kumar, Suhas Ravindra Bavikar, Chebolu Naga Sesha Sai Pavan Kumar, Rong-jie CheinAbstract:A highly efficient one-pot procedure was developed for the synthesis of various 2′-hydroxychalcones from phenyl diethylcarbamate, featuring consecutive Snieckus–Fries Rearrangement, anionic Si → C alkyl Rearrangement, and Claisen–Schmidt condensation in a single operation. The applicability of this protocol was demonstrated by the highly efficient synthesis of the anti-inflammatory natural product lonchocarpin. The mechanism insight is also provided
Etsuko Tokunaga - One of the best experts on this subject based on the ideXlab platform.
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Remote Anionic Fries Rearrangement of Sulfonates: Regioselective Synthesis of Indole Triflones.
ChemInform, 2013Co-Authors: Misaki Taniguchi, Guokai Liu, Etsuko Tokunaga, Ayaka Azuma, Norio ShibataAbstract:An unusual NaH-mediated 1,5-thia-Fries Rearrangement providing the title compounds is presented.
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Remote anionic Fries Rearrangement of sulfonates: regioselective synthesis of indole triflones.
Organic letters, 2013Co-Authors: Misaki Taniguchi, Guokai Liu, Etsuko Tokunaga, Ayaka Azuma, Norio ShibataAbstract:An unusual NaH-mediated remote anionic 1,5-thia-Fries Rearrangement reaction was developed. This method provides an efficient approach for the regioselective synthesis of not only 2-(2-hydroxyphenyl)-3-indole triflones but also related 3-sulfonylindoles.
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Regioselective Synthesis of Heteroaryl Triflones by LDA (Lithium Diisopropylamide)-Mediated Anionic Thia-Fries Rearrangement
Organic letters, 2012Co-Authors: Xin Wang, Guokai Liu, Etsuko Tokunaga, Norio ShibataAbstract:Novel heteroaryl triflones including oxindole, pyrazolone, pyridine, and quinoline derivatives have been regioselectively synthesized by LDA-mediated thia-Fries Rearrangement for the first time. These reactions are also the first examples of the application of anionic thia-Fries Rearrangement in heteroaromatic compounds.
