The Experts below are selected from a list of 255 Experts worldwide ranked by ideXlab platform
Jean-claude Chénieux - One of the best experts on this subject based on the ideXlab platform.
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Furoquinoline alkaloid accumulation in Fagara zanthoxyloides cell cultures is highly dependent on the presence of exogenous benzylaminopurine
Plant Growth Regulation, 1996Co-Authors: Eric Couillerot, Jeanclaude Jardillier, Catherine Caron, Jean-claude Audran, Jean-claude ChénieuxAbstract:Culturing a non-habituated cell line of Fagara zanthoxyloides Lam. (Rutaceae) in either auxin-free medium or cytokinin-free medium led to opposite effects on Furoquinoline accumulation. It appeared that production of skimmianine and γ-fagarine in the cells was strongly correlated with the presence of exogenous BAP: the levels of both alkaloids were 9 times lower when cells were cultured without cytokinin than in the control culture. NAA removal induced a slight stimulation of skimmianine and γ-fagarine accumulations, 1.2 and 1.9 times respectively. Culturing the cells in a PGR-free medium generated skimmianine and γ-fagarine levels that were 3.5 and 2.1 times lower, respectively, confirming the opposite effects of BAP and NAA on Furoquinoline accumulation. Growth was only slightly inhibited when cells were cultured for one passage in the PGR-modified media.
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Benzophenanthridine and Furoquinoline accumulation in cell suspension cultures of Fagara zanthoxyloides
Phytochemistry, 1994Co-Authors: Eric Couillerot, Leopold Comoe, Jeanclaude Jardillier, Catherine Caron, Jean-claude Audran, Pascal Molinatti, Louisette Le Men-olivier, Monique Zeches, Jean-claude ChénieuxAbstract:Abstract In vitro cell culture of Fagara zanthoxyloides is reported for the first time. The cell suspension cultures produced fagaronine, but the production of this metabolite was lost after several subcultures, whereas Furoquinoline accumulation remained high and constant.
Eric Couillerot - One of the best experts on this subject based on the ideXlab platform.
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Furoquinoline alkaloid accumulation in Fagara zanthoxyloides cell cultures is highly dependent on the presence of exogenous benzylaminopurine
Plant Growth Regulation, 1996Co-Authors: Eric Couillerot, Jeanclaude Jardillier, Catherine Caron, Jean-claude Audran, Jean-claude ChénieuxAbstract:Culturing a non-habituated cell line of Fagara zanthoxyloides Lam. (Rutaceae) in either auxin-free medium or cytokinin-free medium led to opposite effects on Furoquinoline accumulation. It appeared that production of skimmianine and γ-fagarine in the cells was strongly correlated with the presence of exogenous BAP: the levels of both alkaloids were 9 times lower when cells were cultured without cytokinin than in the control culture. NAA removal induced a slight stimulation of skimmianine and γ-fagarine accumulations, 1.2 and 1.9 times respectively. Culturing the cells in a PGR-free medium generated skimmianine and γ-fagarine levels that were 3.5 and 2.1 times lower, respectively, confirming the opposite effects of BAP and NAA on Furoquinoline accumulation. Growth was only slightly inhibited when cells were cultured for one passage in the PGR-modified media.
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Benzophenanthridine and Furoquinoline accumulation in cell suspension cultures of Fagara zanthoxyloides
Phytochemistry, 1994Co-Authors: Eric Couillerot, Leopold Comoe, Jeanclaude Jardillier, Catherine Caron, Jean-claude Audran, Pascal Molinatti, Louisette Le Men-olivier, Monique Zeches, Jean-claude ChénieuxAbstract:Abstract In vitro cell culture of Fagara zanthoxyloides is reported for the first time. The cell suspension cultures produced fagaronine, but the production of this metabolite was lost after several subcultures, whereas Furoquinoline accumulation remained high and constant.
Min Shi - One of the best experts on this subject based on the ideXlab platform.
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Thermally Induced Formal [3 + 2] Cyclization of ortho-Aminoaryl-Tethered Alkylidenecyclopropanes: Facile Synthesis of Furoquinoline and Thienoquinoline Derivatives.
ChemInform, 2016Co-Authors: Min ShiAbstract:A novel and efficient synthetic protocol to access Furoquinoline and thienoquinoline derivatives is presented.
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thermally induced formal 3 2 cyclization of ortho aminoaryl tethered alkylidenecyclopropanes facile synthesis of Furoquinoline and thienoquinoline derivatives
ChemInform, 2016Co-Authors: Min ShiAbstract:A novel and efficient synthetic protocol to access Furoquinoline and thienoquinoline derivatives is presented.
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Thermally induced formal [3+2] cyclization of ortho-aminoaryl-tethered alkylidenecyclopropanes: facile synthesis of Furoquinoline and thienoquinoline derivatives
Chemical communications (Cambridge England), 2016Co-Authors: Min ShiAbstract:We have developed a facile synthetic method to access Furoquinoline and thienoquinoline derivatives via a thermally induced ring-opening and cyclization reaction from ortho-aminoaryl-tethered alkylidenecyclopropanes with the in situ generation of isocyanates or isothiocyanates. These reactions exhibited excellent yields and functional group tolerance under metal-free conditions.
Herman P. Perzanowski - One of the best experts on this subject based on the ideXlab platform.
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Furoquinoline alkaloids from Teclea nobilis.
Phytochemistry, 2003Co-Authors: Adnan J. Al-rehaily, Mohammad Ahmad, Ilias Muhammad, Assad A. Al-thukair, Herman P. PerzanowskiAbstract:Abstract Five new Furoquinoline alkaloids, namely tecleabine (1), tecleoxine (2), isotecleoxine (3), methylnkolbisine (4) and chlorodesnkolbisine (5) were isolated from the aerial parts of Teclea nobilis, together with seven known Furoquinoline derivatives; one acridone alkaloid, and one known flavanone. The structures of the alkaloids 1–5 were established by 1D and 2D NMR spectral data, including COSY, HMQC and HMBC experiments, as well as HRMS.
Philippe Belmont - One of the best experts on this subject based on the ideXlab platform.
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Synthesis and Reactivity of Furoquinolines Bearing an External Methylene‐Bond: Access to Reduced and Spirocyclic Structures.
ChemInform, 2011Co-Authors: Xavier Bantreil, Carine Vaxelaire, Thomas Godet, Evelyne Parker, Carole Sauer, Philippe BelmontAbstract:A previously reported tandem acetalization/cycloisomerization process catalyzed by polymeric silver imidazolide is extended to a variety of alcohols to give Furoquinolines (III) and (XI).
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Synthesis and reactivity of Furoquinolines bearing an external methylene-bond: access to reduced and spirocyclic structures.
Organic & biomolecular chemistry, 2011Co-Authors: Xavier Bantreil, Carine Vaxelaire, Thomas Godet, Evelyne Parker, Carole Sauer, Philippe BelmontAbstract:A family of Furoquinolines were efficiently obtained through a tandem acetalization/cycloisomerization process catalyzed by (5 mol%) silver imidazolate polymer and triphenylphosphine, and diversity was brought by the use of 7 different alcohol groups. From these Furoquinolines, 3 examples of reduced derivatives could be obtained (d.r. up to 94 : 6), 10 different spiroketal derivatives by hetero-Diels–Alder reaction (d.r. up to 20 : 1), 8 hetero-[5,5]-spirocycles by cycloaddition with dibromoformaldoxime (d.r. up to 86 : 14) and finally 6 hetero-[5,6]-spirocycles by [4 + 2] cycloaddition with ethyl 3-bromo-2-(hydroxyimino)propanoate (d.r. up to 90 : 10).
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Silver-catalyzed Furoquinolines synthesis: from nitrogen effects to the use of silver imidazolate polymer as a new and robust silver catalyst
Chemical communications (Cambridge England), 2010Co-Authors: Evelyne Parker, Thomas Godet, Nicolas Leconte, Philippe BelmontAbstract:Silver-catalyzed tandem acetalization and cycloisomerization reactions were found to lead to various Furoquinolines, and a nitrogen effect was noticed for AgOTf reactivity, since the cyclization mode switched from 6-endo-dig to 5-exo-dig; from these observations silver imidazolate polymer is proposed as a stable silver catalyst.