The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Shogo Nakano - One of the best experts on this subject based on the ideXlab platform.
-
abstract p4 13 12 impact of an image Fusion Technique for preoperative planning in breast conserving surgery in patients with non mass enhancement on mri
Cancer Research, 2020Co-Authors: Shogo Nakano, Junko Kousaka, Takahito Ando, Kimihito Fujii, Yukako Mouri, Hirona Banno, Manami Goto, Kenjiro SuzukiAbstract:[Objective] The potential benefit of preoperative MRI is still being controversial and international guidelines do not recommend MRI for routine preoperative assessment. However, when breast conserving surgery (BCS) is considered for non-mass enhancement (NME), an area of enhancement without an associated space occupying mass or focus, biopsy-proven malignancy, the precise localization in surgical position is required. Although breast ultrasound (US) plays an adjunctive role in evaluation of MRI findings in preoperative planning for BCS, the US morphology least likely to have an US correlation was NME, not a mass enhancement or a focus, and the identification rate of NME in second look US was heterogeneous. Recently, real-time virtual sonography (RVS), which coordinates US with MRI that uses an image Fusion Technique by using magnet position tracking system, has been introduced in breast imaging. The purpose of this study was to evaluate the effect of preoperative planning using RVS on BCS in patients with NME. [Methods] We enrolled 12 consecutive patients who had lesions with NME that exceeded the US hypoechoic area, in which it was particularly difficult to evaluate the tumor margin. During preoperative planning before BCS, RVS was used to delineate the enhancing area on the breast surface after additional supine breast MRI was performed. We analyzed both the surgical margin positivity rate and the reoperation rate. [Results] The preoperative diagnosis by core needle biopsy were 7 DCIS and 5 invasive ductal carcinoma. NME distribution types were 5 segmental, 4 branching-ductal and 3 regional. The median diameters of the NME and hypo-echoic lesions were 24 mm (range: 12-39 mm) and 8.0 mm (range: 4.9-18 mm), respectively (p = 0.0002). After RVS-derived skin marking was performed on the surface of the affected breast, 7 lumpectomy and 5 quadrantectomy were conducted. The surgical margins were positive in 2 (17%) patients. The patients with positive margins were found to have ductal carcinoma in situ. None of the patients required additional resection. [Conclusion] Although further prospective studies are required, the findings of our preliminary study suggest that preoperative planning using RVS for BCS in patients with NME could improve both a surgical margin positive rate and a reoperation rate. Citation Format: Shogo Nakano, Kimihito Fujii, Yukako Mouri, Junko Kousaka, Takahito Ando, Mirai Ido, Manami Goto, Yukie Ito, Hirona Banno, Kenjiro Suzuki. Impact of an image Fusion Technique for preoperative planning in breast conserving surgery in patients with non -mass enhancement on MRI [abstract]. In: Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P4-13-12.
-
pre operative planning using real time virtual sonography an mri ultrasound image Fusion Technique for breast conserving surgery in patients with non mass enhancement on breast mri a preliminary study
Ultrasound in Medicine and Biology, 2018Co-Authors: Takahito Ando, Junko Kousaka, Kimihito Fujii, Yukako Mouri, Manami Osawa, Rie Watanebe, Junko Kimura, Tsuneo Ishiguchi, Shogo Nakano, Tsuneo ImaiAbstract:Abstract The purpose of this retrospective study was to evaluate the effect of pre-operative planning using real-time virtual sonography (RVS), a magnetic resonance imaging (MRI)/ultrasound (US) image Fusion Technique on breast-conserving surgery (BCS) in patients with non-mass enhancement (NME) on breast MRI. Between 2011 and 2015, we enrolled 12 consecutive patients who had lesions with NME that exceeded the US hypo-echoic area, in which it was particularly difficult to evaluate the tumor margin. During pre-operative planning before breast-conserving surgery, RVS was used to delineate the enhancing area on the breast surface after additional supine breast MRI was performed. We analyzed both the surgical margin positivity rate and the re-operation rate. All NME lesions corresponded to the index cancer. In all patients, the diameter of the NME lesion was greater than that of the hypo-echoic lesion. The median diameters of the NME and hypo-echoic lesions were 24 mm (range: 12–39 mm) and 8.0 mm (range: 4.9–18 mm), respectively (p = 0.0002). After RVS-derived skin marking was performed on the surface of the affected breast, lumpectomy and quadrantectomy were conducted in 7 and 5 patients, respectively. The surgical margins were negative in 10 (83%) patients. Two patients with positive margins were found to have ductal carcinoma in situ in 1 duct each, 2.4 and 3.2 mm from the resection margin, respectively. None of the patients required additional resection. Although further prospective studies are required, the findings of our preliminary study suggest that it is very well possible that the use of RVS-derived skin marking during pre-operative planning for BCS in patients with NME would have resulted in surgical outcomes similar to or better than those obtained without the use of such marking.
-
abstract p4 02 13 breast ultrasound surveillance with image Fusion Technique in a short interval follow up for bi rads category 3 mass lesions
Cancer Research, 2017Co-Authors: Shogo Nakano, Junko Kousaka, Kimihito Fujii, Yukako Mouri, Takahito AndoAbstract:PURPOSE: Breast ultrasound (US) is a diagnostic imaging modality that is now widely used as an adjunct to mammography for evaluation of breast abnormalities. In the Breast Imaging-Reporting and Data System (BI-RADS) lexicon, a solid mass with an oval shape, well-circumscribed margins and parallel orientation is classified as category 3 (BI-RADS category 3 mass lesions) . This mass should have a risk of malignancy of METHOD AND MATERIALS: We enrolled 20 women (23 lesions) with more than 24 months of follow-up after classification as BI-RADS category 3 during initial US. US surveillance was scheduled at 6, 12 and 24 months. Three-dimensional assessment of morphologic features was performed while serially checking past US volume data corresponding to the present US probe position. Measurement of the target lesion diameter was performed after the probe was adjusted to include the maximum diameter of a past US image at each visit. RESULTS: RVS was technically successful in 100% of patients. All target lesions were detected, including two iso-echoic lesions. The mean target lesion diameters at baseline and at 6, 12 and 24 months were 8.2+4.2, 8.4+4.5, 8.1+4.5 and 8.3+5.0 mm, respectively . Statistical analysis using a Friedman test with multiple comparisons revealed no significant difference between the diameters at each time point (p = 0.785). RVS was used to directly compare the US morphologic characteristics and sized of lesions. Furthermore, the RVS data can be reproduced in their entirety for independent review at a later date by using stored US volume data. CONCLUSION:Our results suggest that RVS is reproducible, operator-independent Technique for comparison of US images of BI-RADS category 3 mass lesions obtained at different time points. Citation Format: Nakano S, Fujii K, Kousaka J, Mouri Y, Ando T. Breast ultrasound surveillance with image Fusion Technique in a short-interval follow-up for BI-RADS category 3 mass lesions [abstract]. In: Proceedings of the 2016 San Antonio Breast Cancer Symposium; 2016 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2017;77(4 Suppl):Abstract nr P4-02-13.
-
targeted sonography using an image Fusion Technique for evaluation of incidentally detected breast lesions on chest ct a pilot study
Breast Cancer, 2016Co-Authors: Junko Kousaka, Takahito Ando, Rie Tetsuka, Kimihito Fujii, Miwa Yoshida, Yukako Shiomimouri, Yuko Imai, Shogo Nakano, Manami Goto, Tsuneo ImaiAbstract:Background With increasing use of computed tomography (CT), incidentally detected breast lesions are being encountered more frequently. The aim of our study was to verify the utility of targeted sonography using an image Fusion Technique, real-time virtual sonography (RVS) that coordinates real-time sonography images with previously obtained CT images using a magnetic position tracking system, for evaluation of incidentally detected breast lesions on chest CT.
-
reproducible surveillance breast ultrasound using an image Fusion Technique in a short interval follow up for bi rads 3 lesions a pilot study
Ultrasound in Medicine and Biology, 2014Co-Authors: Shogo Nakano, Junko Kousaka, Takahito Ando, Rie Tetsuka, Kimihito Fujii, Miwa Yoshida, Yukako Shiomimouri, Takashi Fukutomi, Tsuneo Imai, Tsuneo IshiguchiAbstract:Abstract The aim of our study was to verify the utility of surveillance ultrasound (US) using real-time virtual sonography (RVS) - to coordinate present US images with past US images reconstructed from previously acquired US volume data using an image Fusion Technique - for short-interval follow-up of Breast Imaging-Reporting and Data System (BI-RADS) category 3 mass lesions. We enrolled 20 women (23 lesions) with more than 24 mo of follow-up after classification as BI-RADS category 3 during initial US. US surveillance was scheduled at 6, 12 and 24 mo. Measurement of the target lesion diameter was performed after the probe was adjusted to include the maximum diameter of a past US image at each visit. RVS was technically successful in 100% of patients. All target lesions were detected, including two iso-echoic lesions. The mean target lesion diameters at baseline and at 6, 12 and 24 mo were 8.2 ± 4.2, 8.4 ± 4.5, 8.1 ± 4.5 and 8.3 ± 5.0 mm, respectively ( p = 0.785). Our results suggest that RVS is a reproducible, operator-independent Technique for comparison of US images of BI-RADS category 3 mass lesions obtained at different time points.
Takahito Ando - One of the best experts on this subject based on the ideXlab platform.
-
abstract p4 13 12 impact of an image Fusion Technique for preoperative planning in breast conserving surgery in patients with non mass enhancement on mri
Cancer Research, 2020Co-Authors: Shogo Nakano, Junko Kousaka, Takahito Ando, Kimihito Fujii, Yukako Mouri, Hirona Banno, Manami Goto, Kenjiro SuzukiAbstract:[Objective] The potential benefit of preoperative MRI is still being controversial and international guidelines do not recommend MRI for routine preoperative assessment. However, when breast conserving surgery (BCS) is considered for non-mass enhancement (NME), an area of enhancement without an associated space occupying mass or focus, biopsy-proven malignancy, the precise localization in surgical position is required. Although breast ultrasound (US) plays an adjunctive role in evaluation of MRI findings in preoperative planning for BCS, the US morphology least likely to have an US correlation was NME, not a mass enhancement or a focus, and the identification rate of NME in second look US was heterogeneous. Recently, real-time virtual sonography (RVS), which coordinates US with MRI that uses an image Fusion Technique by using magnet position tracking system, has been introduced in breast imaging. The purpose of this study was to evaluate the effect of preoperative planning using RVS on BCS in patients with NME. [Methods] We enrolled 12 consecutive patients who had lesions with NME that exceeded the US hypoechoic area, in which it was particularly difficult to evaluate the tumor margin. During preoperative planning before BCS, RVS was used to delineate the enhancing area on the breast surface after additional supine breast MRI was performed. We analyzed both the surgical margin positivity rate and the reoperation rate. [Results] The preoperative diagnosis by core needle biopsy were 7 DCIS and 5 invasive ductal carcinoma. NME distribution types were 5 segmental, 4 branching-ductal and 3 regional. The median diameters of the NME and hypo-echoic lesions were 24 mm (range: 12-39 mm) and 8.0 mm (range: 4.9-18 mm), respectively (p = 0.0002). After RVS-derived skin marking was performed on the surface of the affected breast, 7 lumpectomy and 5 quadrantectomy were conducted. The surgical margins were positive in 2 (17%) patients. The patients with positive margins were found to have ductal carcinoma in situ. None of the patients required additional resection. [Conclusion] Although further prospective studies are required, the findings of our preliminary study suggest that preoperative planning using RVS for BCS in patients with NME could improve both a surgical margin positive rate and a reoperation rate. Citation Format: Shogo Nakano, Kimihito Fujii, Yukako Mouri, Junko Kousaka, Takahito Ando, Mirai Ido, Manami Goto, Yukie Ito, Hirona Banno, Kenjiro Suzuki. Impact of an image Fusion Technique for preoperative planning in breast conserving surgery in patients with non -mass enhancement on MRI [abstract]. In: Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P4-13-12.
-
pre operative planning using real time virtual sonography an mri ultrasound image Fusion Technique for breast conserving surgery in patients with non mass enhancement on breast mri a preliminary study
Ultrasound in Medicine and Biology, 2018Co-Authors: Takahito Ando, Junko Kousaka, Kimihito Fujii, Yukako Mouri, Manami Osawa, Rie Watanebe, Junko Kimura, Tsuneo Ishiguchi, Shogo Nakano, Tsuneo ImaiAbstract:Abstract The purpose of this retrospective study was to evaluate the effect of pre-operative planning using real-time virtual sonography (RVS), a magnetic resonance imaging (MRI)/ultrasound (US) image Fusion Technique on breast-conserving surgery (BCS) in patients with non-mass enhancement (NME) on breast MRI. Between 2011 and 2015, we enrolled 12 consecutive patients who had lesions with NME that exceeded the US hypo-echoic area, in which it was particularly difficult to evaluate the tumor margin. During pre-operative planning before breast-conserving surgery, RVS was used to delineate the enhancing area on the breast surface after additional supine breast MRI was performed. We analyzed both the surgical margin positivity rate and the re-operation rate. All NME lesions corresponded to the index cancer. In all patients, the diameter of the NME lesion was greater than that of the hypo-echoic lesion. The median diameters of the NME and hypo-echoic lesions were 24 mm (range: 12–39 mm) and 8.0 mm (range: 4.9–18 mm), respectively (p = 0.0002). After RVS-derived skin marking was performed on the surface of the affected breast, lumpectomy and quadrantectomy were conducted in 7 and 5 patients, respectively. The surgical margins were negative in 10 (83%) patients. Two patients with positive margins were found to have ductal carcinoma in situ in 1 duct each, 2.4 and 3.2 mm from the resection margin, respectively. None of the patients required additional resection. Although further prospective studies are required, the findings of our preliminary study suggest that it is very well possible that the use of RVS-derived skin marking during pre-operative planning for BCS in patients with NME would have resulted in surgical outcomes similar to or better than those obtained without the use of such marking.
-
abstract p4 02 13 breast ultrasound surveillance with image Fusion Technique in a short interval follow up for bi rads category 3 mass lesions
Cancer Research, 2017Co-Authors: Shogo Nakano, Junko Kousaka, Kimihito Fujii, Yukako Mouri, Takahito AndoAbstract:PURPOSE: Breast ultrasound (US) is a diagnostic imaging modality that is now widely used as an adjunct to mammography for evaluation of breast abnormalities. In the Breast Imaging-Reporting and Data System (BI-RADS) lexicon, a solid mass with an oval shape, well-circumscribed margins and parallel orientation is classified as category 3 (BI-RADS category 3 mass lesions) . This mass should have a risk of malignancy of METHOD AND MATERIALS: We enrolled 20 women (23 lesions) with more than 24 months of follow-up after classification as BI-RADS category 3 during initial US. US surveillance was scheduled at 6, 12 and 24 months. Three-dimensional assessment of morphologic features was performed while serially checking past US volume data corresponding to the present US probe position. Measurement of the target lesion diameter was performed after the probe was adjusted to include the maximum diameter of a past US image at each visit. RESULTS: RVS was technically successful in 100% of patients. All target lesions were detected, including two iso-echoic lesions. The mean target lesion diameters at baseline and at 6, 12 and 24 months were 8.2+4.2, 8.4+4.5, 8.1+4.5 and 8.3+5.0 mm, respectively . Statistical analysis using a Friedman test with multiple comparisons revealed no significant difference between the diameters at each time point (p = 0.785). RVS was used to directly compare the US morphologic characteristics and sized of lesions. Furthermore, the RVS data can be reproduced in their entirety for independent review at a later date by using stored US volume data. CONCLUSION:Our results suggest that RVS is reproducible, operator-independent Technique for comparison of US images of BI-RADS category 3 mass lesions obtained at different time points. Citation Format: Nakano S, Fujii K, Kousaka J, Mouri Y, Ando T. Breast ultrasound surveillance with image Fusion Technique in a short-interval follow-up for BI-RADS category 3 mass lesions [abstract]. In: Proceedings of the 2016 San Antonio Breast Cancer Symposium; 2016 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2017;77(4 Suppl):Abstract nr P4-02-13.
-
targeted sonography using an image Fusion Technique for evaluation of incidentally detected breast lesions on chest ct a pilot study
Breast Cancer, 2016Co-Authors: Junko Kousaka, Takahito Ando, Rie Tetsuka, Kimihito Fujii, Miwa Yoshida, Yukako Shiomimouri, Yuko Imai, Shogo Nakano, Manami Goto, Tsuneo ImaiAbstract:Background With increasing use of computed tomography (CT), incidentally detected breast lesions are being encountered more frequently. The aim of our study was to verify the utility of targeted sonography using an image Fusion Technique, real-time virtual sonography (RVS) that coordinates real-time sonography images with previously obtained CT images using a magnetic position tracking system, for evaluation of incidentally detected breast lesions on chest CT.
-
reproducible surveillance breast ultrasound using an image Fusion Technique in a short interval follow up for bi rads 3 lesions a pilot study
Ultrasound in Medicine and Biology, 2014Co-Authors: Shogo Nakano, Junko Kousaka, Takahito Ando, Rie Tetsuka, Kimihito Fujii, Miwa Yoshida, Yukako Shiomimouri, Takashi Fukutomi, Tsuneo Imai, Tsuneo IshiguchiAbstract:Abstract The aim of our study was to verify the utility of surveillance ultrasound (US) using real-time virtual sonography (RVS) - to coordinate present US images with past US images reconstructed from previously acquired US volume data using an image Fusion Technique - for short-interval follow-up of Breast Imaging-Reporting and Data System (BI-RADS) category 3 mass lesions. We enrolled 20 women (23 lesions) with more than 24 mo of follow-up after classification as BI-RADS category 3 during initial US. US surveillance was scheduled at 6, 12 and 24 mo. Measurement of the target lesion diameter was performed after the probe was adjusted to include the maximum diameter of a past US image at each visit. RVS was technically successful in 100% of patients. All target lesions were detected, including two iso-echoic lesions. The mean target lesion diameters at baseline and at 6, 12 and 24 mo were 8.2 ± 4.2, 8.4 ± 4.5, 8.1 ± 4.5 and 8.3 ± 5.0 mm, respectively ( p = 0.785). Our results suggest that RVS is a reproducible, operator-independent Technique for comparison of US images of BI-RADS category 3 mass lesions obtained at different time points.
Kimihito Fujii - One of the best experts on this subject based on the ideXlab platform.
-
abstract p4 13 12 impact of an image Fusion Technique for preoperative planning in breast conserving surgery in patients with non mass enhancement on mri
Cancer Research, 2020Co-Authors: Shogo Nakano, Junko Kousaka, Takahito Ando, Kimihito Fujii, Yukako Mouri, Hirona Banno, Manami Goto, Kenjiro SuzukiAbstract:[Objective] The potential benefit of preoperative MRI is still being controversial and international guidelines do not recommend MRI for routine preoperative assessment. However, when breast conserving surgery (BCS) is considered for non-mass enhancement (NME), an area of enhancement without an associated space occupying mass or focus, biopsy-proven malignancy, the precise localization in surgical position is required. Although breast ultrasound (US) plays an adjunctive role in evaluation of MRI findings in preoperative planning for BCS, the US morphology least likely to have an US correlation was NME, not a mass enhancement or a focus, and the identification rate of NME in second look US was heterogeneous. Recently, real-time virtual sonography (RVS), which coordinates US with MRI that uses an image Fusion Technique by using magnet position tracking system, has been introduced in breast imaging. The purpose of this study was to evaluate the effect of preoperative planning using RVS on BCS in patients with NME. [Methods] We enrolled 12 consecutive patients who had lesions with NME that exceeded the US hypoechoic area, in which it was particularly difficult to evaluate the tumor margin. During preoperative planning before BCS, RVS was used to delineate the enhancing area on the breast surface after additional supine breast MRI was performed. We analyzed both the surgical margin positivity rate and the reoperation rate. [Results] The preoperative diagnosis by core needle biopsy were 7 DCIS and 5 invasive ductal carcinoma. NME distribution types were 5 segmental, 4 branching-ductal and 3 regional. The median diameters of the NME and hypo-echoic lesions were 24 mm (range: 12-39 mm) and 8.0 mm (range: 4.9-18 mm), respectively (p = 0.0002). After RVS-derived skin marking was performed on the surface of the affected breast, 7 lumpectomy and 5 quadrantectomy were conducted. The surgical margins were positive in 2 (17%) patients. The patients with positive margins were found to have ductal carcinoma in situ. None of the patients required additional resection. [Conclusion] Although further prospective studies are required, the findings of our preliminary study suggest that preoperative planning using RVS for BCS in patients with NME could improve both a surgical margin positive rate and a reoperation rate. Citation Format: Shogo Nakano, Kimihito Fujii, Yukako Mouri, Junko Kousaka, Takahito Ando, Mirai Ido, Manami Goto, Yukie Ito, Hirona Banno, Kenjiro Suzuki. Impact of an image Fusion Technique for preoperative planning in breast conserving surgery in patients with non -mass enhancement on MRI [abstract]. In: Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P4-13-12.
-
pre operative planning using real time virtual sonography an mri ultrasound image Fusion Technique for breast conserving surgery in patients with non mass enhancement on breast mri a preliminary study
Ultrasound in Medicine and Biology, 2018Co-Authors: Takahito Ando, Junko Kousaka, Kimihito Fujii, Yukako Mouri, Manami Osawa, Rie Watanebe, Junko Kimura, Tsuneo Ishiguchi, Shogo Nakano, Tsuneo ImaiAbstract:Abstract The purpose of this retrospective study was to evaluate the effect of pre-operative planning using real-time virtual sonography (RVS), a magnetic resonance imaging (MRI)/ultrasound (US) image Fusion Technique on breast-conserving surgery (BCS) in patients with non-mass enhancement (NME) on breast MRI. Between 2011 and 2015, we enrolled 12 consecutive patients who had lesions with NME that exceeded the US hypo-echoic area, in which it was particularly difficult to evaluate the tumor margin. During pre-operative planning before breast-conserving surgery, RVS was used to delineate the enhancing area on the breast surface after additional supine breast MRI was performed. We analyzed both the surgical margin positivity rate and the re-operation rate. All NME lesions corresponded to the index cancer. In all patients, the diameter of the NME lesion was greater than that of the hypo-echoic lesion. The median diameters of the NME and hypo-echoic lesions were 24 mm (range: 12–39 mm) and 8.0 mm (range: 4.9–18 mm), respectively (p = 0.0002). After RVS-derived skin marking was performed on the surface of the affected breast, lumpectomy and quadrantectomy were conducted in 7 and 5 patients, respectively. The surgical margins were negative in 10 (83%) patients. Two patients with positive margins were found to have ductal carcinoma in situ in 1 duct each, 2.4 and 3.2 mm from the resection margin, respectively. None of the patients required additional resection. Although further prospective studies are required, the findings of our preliminary study suggest that it is very well possible that the use of RVS-derived skin marking during pre-operative planning for BCS in patients with NME would have resulted in surgical outcomes similar to or better than those obtained without the use of such marking.
-
abstract p4 02 13 breast ultrasound surveillance with image Fusion Technique in a short interval follow up for bi rads category 3 mass lesions
Cancer Research, 2017Co-Authors: Shogo Nakano, Junko Kousaka, Kimihito Fujii, Yukako Mouri, Takahito AndoAbstract:PURPOSE: Breast ultrasound (US) is a diagnostic imaging modality that is now widely used as an adjunct to mammography for evaluation of breast abnormalities. In the Breast Imaging-Reporting and Data System (BI-RADS) lexicon, a solid mass with an oval shape, well-circumscribed margins and parallel orientation is classified as category 3 (BI-RADS category 3 mass lesions) . This mass should have a risk of malignancy of METHOD AND MATERIALS: We enrolled 20 women (23 lesions) with more than 24 months of follow-up after classification as BI-RADS category 3 during initial US. US surveillance was scheduled at 6, 12 and 24 months. Three-dimensional assessment of morphologic features was performed while serially checking past US volume data corresponding to the present US probe position. Measurement of the target lesion diameter was performed after the probe was adjusted to include the maximum diameter of a past US image at each visit. RESULTS: RVS was technically successful in 100% of patients. All target lesions were detected, including two iso-echoic lesions. The mean target lesion diameters at baseline and at 6, 12 and 24 months were 8.2+4.2, 8.4+4.5, 8.1+4.5 and 8.3+5.0 mm, respectively . Statistical analysis using a Friedman test with multiple comparisons revealed no significant difference between the diameters at each time point (p = 0.785). RVS was used to directly compare the US morphologic characteristics and sized of lesions. Furthermore, the RVS data can be reproduced in their entirety for independent review at a later date by using stored US volume data. CONCLUSION:Our results suggest that RVS is reproducible, operator-independent Technique for comparison of US images of BI-RADS category 3 mass lesions obtained at different time points. Citation Format: Nakano S, Fujii K, Kousaka J, Mouri Y, Ando T. Breast ultrasound surveillance with image Fusion Technique in a short-interval follow-up for BI-RADS category 3 mass lesions [abstract]. In: Proceedings of the 2016 San Antonio Breast Cancer Symposium; 2016 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2017;77(4 Suppl):Abstract nr P4-02-13.
-
targeted sonography using an image Fusion Technique for evaluation of incidentally detected breast lesions on chest ct a pilot study
Breast Cancer, 2016Co-Authors: Junko Kousaka, Takahito Ando, Rie Tetsuka, Kimihito Fujii, Miwa Yoshida, Yukako Shiomimouri, Yuko Imai, Shogo Nakano, Manami Goto, Tsuneo ImaiAbstract:Background With increasing use of computed tomography (CT), incidentally detected breast lesions are being encountered more frequently. The aim of our study was to verify the utility of targeted sonography using an image Fusion Technique, real-time virtual sonography (RVS) that coordinates real-time sonography images with previously obtained CT images using a magnetic position tracking system, for evaluation of incidentally detected breast lesions on chest CT.
-
reproducible surveillance breast ultrasound using an image Fusion Technique in a short interval follow up for bi rads 3 lesions a pilot study
Ultrasound in Medicine and Biology, 2014Co-Authors: Shogo Nakano, Junko Kousaka, Takahito Ando, Rie Tetsuka, Kimihito Fujii, Miwa Yoshida, Yukako Shiomimouri, Takashi Fukutomi, Tsuneo Imai, Tsuneo IshiguchiAbstract:Abstract The aim of our study was to verify the utility of surveillance ultrasound (US) using real-time virtual sonography (RVS) - to coordinate present US images with past US images reconstructed from previously acquired US volume data using an image Fusion Technique - for short-interval follow-up of Breast Imaging-Reporting and Data System (BI-RADS) category 3 mass lesions. We enrolled 20 women (23 lesions) with more than 24 mo of follow-up after classification as BI-RADS category 3 during initial US. US surveillance was scheduled at 6, 12 and 24 mo. Measurement of the target lesion diameter was performed after the probe was adjusted to include the maximum diameter of a past US image at each visit. RVS was technically successful in 100% of patients. All target lesions were detected, including two iso-echoic lesions. The mean target lesion diameters at baseline and at 6, 12 and 24 mo were 8.2 ± 4.2, 8.4 ± 4.5, 8.1 ± 4.5 and 8.3 ± 5.0 mm, respectively ( p = 0.785). Our results suggest that RVS is a reproducible, operator-independent Technique for comparison of US images of BI-RADS category 3 mass lesions obtained at different time points.
Junko Kousaka - One of the best experts on this subject based on the ideXlab platform.
-
abstract p4 13 12 impact of an image Fusion Technique for preoperative planning in breast conserving surgery in patients with non mass enhancement on mri
Cancer Research, 2020Co-Authors: Shogo Nakano, Junko Kousaka, Takahito Ando, Kimihito Fujii, Yukako Mouri, Hirona Banno, Manami Goto, Kenjiro SuzukiAbstract:[Objective] The potential benefit of preoperative MRI is still being controversial and international guidelines do not recommend MRI for routine preoperative assessment. However, when breast conserving surgery (BCS) is considered for non-mass enhancement (NME), an area of enhancement without an associated space occupying mass or focus, biopsy-proven malignancy, the precise localization in surgical position is required. Although breast ultrasound (US) plays an adjunctive role in evaluation of MRI findings in preoperative planning for BCS, the US morphology least likely to have an US correlation was NME, not a mass enhancement or a focus, and the identification rate of NME in second look US was heterogeneous. Recently, real-time virtual sonography (RVS), which coordinates US with MRI that uses an image Fusion Technique by using magnet position tracking system, has been introduced in breast imaging. The purpose of this study was to evaluate the effect of preoperative planning using RVS on BCS in patients with NME. [Methods] We enrolled 12 consecutive patients who had lesions with NME that exceeded the US hypoechoic area, in which it was particularly difficult to evaluate the tumor margin. During preoperative planning before BCS, RVS was used to delineate the enhancing area on the breast surface after additional supine breast MRI was performed. We analyzed both the surgical margin positivity rate and the reoperation rate. [Results] The preoperative diagnosis by core needle biopsy were 7 DCIS and 5 invasive ductal carcinoma. NME distribution types were 5 segmental, 4 branching-ductal and 3 regional. The median diameters of the NME and hypo-echoic lesions were 24 mm (range: 12-39 mm) and 8.0 mm (range: 4.9-18 mm), respectively (p = 0.0002). After RVS-derived skin marking was performed on the surface of the affected breast, 7 lumpectomy and 5 quadrantectomy were conducted. The surgical margins were positive in 2 (17%) patients. The patients with positive margins were found to have ductal carcinoma in situ. None of the patients required additional resection. [Conclusion] Although further prospective studies are required, the findings of our preliminary study suggest that preoperative planning using RVS for BCS in patients with NME could improve both a surgical margin positive rate and a reoperation rate. Citation Format: Shogo Nakano, Kimihito Fujii, Yukako Mouri, Junko Kousaka, Takahito Ando, Mirai Ido, Manami Goto, Yukie Ito, Hirona Banno, Kenjiro Suzuki. Impact of an image Fusion Technique for preoperative planning in breast conserving surgery in patients with non -mass enhancement on MRI [abstract]. In: Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P4-13-12.
-
pre operative planning using real time virtual sonography an mri ultrasound image Fusion Technique for breast conserving surgery in patients with non mass enhancement on breast mri a preliminary study
Ultrasound in Medicine and Biology, 2018Co-Authors: Takahito Ando, Junko Kousaka, Kimihito Fujii, Yukako Mouri, Manami Osawa, Rie Watanebe, Junko Kimura, Tsuneo Ishiguchi, Shogo Nakano, Tsuneo ImaiAbstract:Abstract The purpose of this retrospective study was to evaluate the effect of pre-operative planning using real-time virtual sonography (RVS), a magnetic resonance imaging (MRI)/ultrasound (US) image Fusion Technique on breast-conserving surgery (BCS) in patients with non-mass enhancement (NME) on breast MRI. Between 2011 and 2015, we enrolled 12 consecutive patients who had lesions with NME that exceeded the US hypo-echoic area, in which it was particularly difficult to evaluate the tumor margin. During pre-operative planning before breast-conserving surgery, RVS was used to delineate the enhancing area on the breast surface after additional supine breast MRI was performed. We analyzed both the surgical margin positivity rate and the re-operation rate. All NME lesions corresponded to the index cancer. In all patients, the diameter of the NME lesion was greater than that of the hypo-echoic lesion. The median diameters of the NME and hypo-echoic lesions were 24 mm (range: 12–39 mm) and 8.0 mm (range: 4.9–18 mm), respectively (p = 0.0002). After RVS-derived skin marking was performed on the surface of the affected breast, lumpectomy and quadrantectomy were conducted in 7 and 5 patients, respectively. The surgical margins were negative in 10 (83%) patients. Two patients with positive margins were found to have ductal carcinoma in situ in 1 duct each, 2.4 and 3.2 mm from the resection margin, respectively. None of the patients required additional resection. Although further prospective studies are required, the findings of our preliminary study suggest that it is very well possible that the use of RVS-derived skin marking during pre-operative planning for BCS in patients with NME would have resulted in surgical outcomes similar to or better than those obtained without the use of such marking.
-
abstract p4 02 13 breast ultrasound surveillance with image Fusion Technique in a short interval follow up for bi rads category 3 mass lesions
Cancer Research, 2017Co-Authors: Shogo Nakano, Junko Kousaka, Kimihito Fujii, Yukako Mouri, Takahito AndoAbstract:PURPOSE: Breast ultrasound (US) is a diagnostic imaging modality that is now widely used as an adjunct to mammography for evaluation of breast abnormalities. In the Breast Imaging-Reporting and Data System (BI-RADS) lexicon, a solid mass with an oval shape, well-circumscribed margins and parallel orientation is classified as category 3 (BI-RADS category 3 mass lesions) . This mass should have a risk of malignancy of METHOD AND MATERIALS: We enrolled 20 women (23 lesions) with more than 24 months of follow-up after classification as BI-RADS category 3 during initial US. US surveillance was scheduled at 6, 12 and 24 months. Three-dimensional assessment of morphologic features was performed while serially checking past US volume data corresponding to the present US probe position. Measurement of the target lesion diameter was performed after the probe was adjusted to include the maximum diameter of a past US image at each visit. RESULTS: RVS was technically successful in 100% of patients. All target lesions were detected, including two iso-echoic lesions. The mean target lesion diameters at baseline and at 6, 12 and 24 months were 8.2+4.2, 8.4+4.5, 8.1+4.5 and 8.3+5.0 mm, respectively . Statistical analysis using a Friedman test with multiple comparisons revealed no significant difference between the diameters at each time point (p = 0.785). RVS was used to directly compare the US morphologic characteristics and sized of lesions. Furthermore, the RVS data can be reproduced in their entirety for independent review at a later date by using stored US volume data. CONCLUSION:Our results suggest that RVS is reproducible, operator-independent Technique for comparison of US images of BI-RADS category 3 mass lesions obtained at different time points. Citation Format: Nakano S, Fujii K, Kousaka J, Mouri Y, Ando T. Breast ultrasound surveillance with image Fusion Technique in a short-interval follow-up for BI-RADS category 3 mass lesions [abstract]. In: Proceedings of the 2016 San Antonio Breast Cancer Symposium; 2016 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2017;77(4 Suppl):Abstract nr P4-02-13.
-
targeted sonography using an image Fusion Technique for evaluation of incidentally detected breast lesions on chest ct a pilot study
Breast Cancer, 2016Co-Authors: Junko Kousaka, Takahito Ando, Rie Tetsuka, Kimihito Fujii, Miwa Yoshida, Yukako Shiomimouri, Yuko Imai, Shogo Nakano, Manami Goto, Tsuneo ImaiAbstract:Background With increasing use of computed tomography (CT), incidentally detected breast lesions are being encountered more frequently. The aim of our study was to verify the utility of targeted sonography using an image Fusion Technique, real-time virtual sonography (RVS) that coordinates real-time sonography images with previously obtained CT images using a magnetic position tracking system, for evaluation of incidentally detected breast lesions on chest CT.
-
reproducible surveillance breast ultrasound using an image Fusion Technique in a short interval follow up for bi rads 3 lesions a pilot study
Ultrasound in Medicine and Biology, 2014Co-Authors: Shogo Nakano, Junko Kousaka, Takahito Ando, Rie Tetsuka, Kimihito Fujii, Miwa Yoshida, Yukako Shiomimouri, Takashi Fukutomi, Tsuneo Imai, Tsuneo IshiguchiAbstract:Abstract The aim of our study was to verify the utility of surveillance ultrasound (US) using real-time virtual sonography (RVS) - to coordinate present US images with past US images reconstructed from previously acquired US volume data using an image Fusion Technique - for short-interval follow-up of Breast Imaging-Reporting and Data System (BI-RADS) category 3 mass lesions. We enrolled 20 women (23 lesions) with more than 24 mo of follow-up after classification as BI-RADS category 3 during initial US. US surveillance was scheduled at 6, 12 and 24 mo. Measurement of the target lesion diameter was performed after the probe was adjusted to include the maximum diameter of a past US image at each visit. RVS was technically successful in 100% of patients. All target lesions were detected, including two iso-echoic lesions. The mean target lesion diameters at baseline and at 6, 12 and 24 mo were 8.2 ± 4.2, 8.4 ± 4.5, 8.1 ± 4.5 and 8.3 ± 5.0 mm, respectively ( p = 0.785). Our results suggest that RVS is a reproducible, operator-independent Technique for comparison of US images of BI-RADS category 3 mass lesions obtained at different time points.
Tsuneo Ishiguchi - One of the best experts on this subject based on the ideXlab platform.
-
pre operative planning using real time virtual sonography an mri ultrasound image Fusion Technique for breast conserving surgery in patients with non mass enhancement on breast mri a preliminary study
Ultrasound in Medicine and Biology, 2018Co-Authors: Takahito Ando, Junko Kousaka, Kimihito Fujii, Yukako Mouri, Manami Osawa, Rie Watanebe, Junko Kimura, Tsuneo Ishiguchi, Shogo Nakano, Tsuneo ImaiAbstract:Abstract The purpose of this retrospective study was to evaluate the effect of pre-operative planning using real-time virtual sonography (RVS), a magnetic resonance imaging (MRI)/ultrasound (US) image Fusion Technique on breast-conserving surgery (BCS) in patients with non-mass enhancement (NME) on breast MRI. Between 2011 and 2015, we enrolled 12 consecutive patients who had lesions with NME that exceeded the US hypo-echoic area, in which it was particularly difficult to evaluate the tumor margin. During pre-operative planning before breast-conserving surgery, RVS was used to delineate the enhancing area on the breast surface after additional supine breast MRI was performed. We analyzed both the surgical margin positivity rate and the re-operation rate. All NME lesions corresponded to the index cancer. In all patients, the diameter of the NME lesion was greater than that of the hypo-echoic lesion. The median diameters of the NME and hypo-echoic lesions were 24 mm (range: 12–39 mm) and 8.0 mm (range: 4.9–18 mm), respectively (p = 0.0002). After RVS-derived skin marking was performed on the surface of the affected breast, lumpectomy and quadrantectomy were conducted in 7 and 5 patients, respectively. The surgical margins were negative in 10 (83%) patients. Two patients with positive margins were found to have ductal carcinoma in situ in 1 duct each, 2.4 and 3.2 mm from the resection margin, respectively. None of the patients required additional resection. Although further prospective studies are required, the findings of our preliminary study suggest that it is very well possible that the use of RVS-derived skin marking during pre-operative planning for BCS in patients with NME would have resulted in surgical outcomes similar to or better than those obtained without the use of such marking.
-
reproducible surveillance breast ultrasound using an image Fusion Technique in a short interval follow up for bi rads 3 lesions a pilot study
Ultrasound in Medicine and Biology, 2014Co-Authors: Shogo Nakano, Junko Kousaka, Takahito Ando, Rie Tetsuka, Kimihito Fujii, Miwa Yoshida, Yukako Shiomimouri, Takashi Fukutomi, Tsuneo Imai, Tsuneo IshiguchiAbstract:Abstract The aim of our study was to verify the utility of surveillance ultrasound (US) using real-time virtual sonography (RVS) - to coordinate present US images with past US images reconstructed from previously acquired US volume data using an image Fusion Technique - for short-interval follow-up of Breast Imaging-Reporting and Data System (BI-RADS) category 3 mass lesions. We enrolled 20 women (23 lesions) with more than 24 mo of follow-up after classification as BI-RADS category 3 during initial US. US surveillance was scheduled at 6, 12 and 24 mo. Measurement of the target lesion diameter was performed after the probe was adjusted to include the maximum diameter of a past US image at each visit. RVS was technically successful in 100% of patients. All target lesions were detected, including two iso-echoic lesions. The mean target lesion diameters at baseline and at 6, 12 and 24 mo were 8.2 ± 4.2, 8.4 ± 4.5, 8.1 ± 4.5 and 8.3 ± 5.0 mm, respectively ( p = 0.785). Our results suggest that RVS is a reproducible, operator-independent Technique for comparison of US images of BI-RADS category 3 mass lesions obtained at different time points.
-
abstract p2 03 06 sonographic evaluation of mri detected lesions of the breast using image Fusion Technique with magnetic navigation
Cancer Research, 2013Co-Authors: Shogo Nakano, Kimihito Fujii, Miwa Yoshida, Takashi Fukutomi, Tsuneo IshiguchiAbstract:[Back ground] Breast magnetic resonance imaging (MRI) is being increasingly evaluated in the screening of patients at high risk of breast cancer and screening of the contralateral breast in newly diagnosed breast cancer. However, the utility of MRI is restricted by its limited specificity and moderate positive predictive value (PPV) because of the overlap of imaging features in benign and malignant lesions. Therefore, tissue sampling should be required for definitive diagnosis of suspicious lesions, especially in cases of MRI-detected lesions. To localize MRI-detected lesions and confirm histopathologic results, MRI-guided biopsy has been introduced with high rates of success. If MRI-detected lesions can be detected with second-look sonography, sonography-guided biopsy, which is more broadly available, less costly, and less time-consuming, is recommended. [Purpose] The aim of this study was to verify the utility of second-look sonography using real-time virtual sonography (RVS), a coordinated sonography and MRI system that uses an image Fusion Technique with magnetic navigation, in the sonographic evaluation of MRI-detected lesions of the breast. [Materials and methods] Of 196 consecutive patients who were examined with breast MRI in our hospital from 2006 to 2009, those who underwent second-look sonography to identify MRI-detected lesions were enrolled in this study. MRI was performed using a 1.5-T imager with the patient in a supine position. To assess the efficacy benefits of RVS, the correlations between lesion detection rates, MRI features, distribution, and histopathological classification on second-look sonography using conventional B-mode or RVS were analyzed. [Results] Of 196 patients, 55 (28%) demonstrated 67 lesions initially detected by MRI, followed by second-look sonography. Of the 67 MRI-detected lesions, 18 (27%) were identified with second-look sonography using conventional B-mode alone, whereas 60 (90%) lesions were detected with second-look sonography using RVS (p < 0.001). The detection rates of 16 focal lesions, 46 mass lesions, 16 lesions sized <5 mm, 45 lesions sized 5-10 mm, 26 lesions situated within the mammary gland, 41 lesions situated around mammary fascia, 24 malignant lesions, and 43 benign lesions were 25%, 26%, 25%, 24%, 42%, 17% 33%, and 23% by conventional B-mode, and were significantly higher at 94%, 89%, 94%, 89%, 88%, 90%, 92% and 88% by RVS, respectively. Of the 7 lesions with no sonographic correlates, 5 could be biopsied by marking MRI information onto the body surface using RVS. Overall, 65 of 67 (97%) MRI-detected lesions were confirmed by histopathological results. [Conclusions] Our results suggest that the additional use of RVS on second-look sonography significantly increases the sonographic detection rate of MRI-detected lesions without operator dependence. The majority of MRI-detected lesions had sonographic correlates and sonography-guided biopsy could subsequently be performed by adding RVS. It might contribute to identifying cases in which MRI-guided biopsy is absolutely necessary. Citation Information: Cancer Res 2013;73(24 Suppl): Abstract nr P2-03-06.
