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Subhankar Chatterjee - One of the best experts on this subject based on the ideXlab platform.

  • Psychrotolerant Sphingobacterium kitahiroshimense LT-2 Isolated from Dhundi Glacier, Himachal Pradesh: Origin Prediction and Future Application.
    Indian Journal of Microbiology, 2018
    Co-Authors: Shivika Sharma, Subhankar Chatterjee
    Abstract:

    A psychrotolerant bacterium, isolated from Dhundi Glacier, Himachal Pradesh (India) was identified as Sphingobacterium kitahiroshimense LT-2 on the basis of biochemical, molecular and phylogenetic analysis. Sphingobacterium kitahiroshimense was first reported from Japan and was isolated from the city of Kitahiroshima, Hokkaido, Japan. In this report we have discussed about the origin of our strain and predicted that air masses and dust associated microbial cells transportation phenomena may be applicable for the origin of this species in this region. Enzymes and secondary metabolites secreted by the genus Sphingobacterium have enormous potentiality regarding their biotechnological Application. Preliminary study of our strain based on metabolic profiling through HPLC showed many new metabolites were secreted by the bacterium when grown in presence of different sugar medium at 28 °C. As far as our knowledge this is the first report about Sphingobacterium species isolated from this region. This preliminary finding will help to draw an idea about the bacterial population in this Himalayan Glaciers (in HP) as well as biotechnological Application of this strain can be explored further.

  • Psychrotolerant Sphingobacterium kitahiroshimense LT-2 Isolated from Dhundi Glacier, Himachal Pradesh: Origin Prediction and Future Application.
    Indian Journal of Microbiology, 2018
    Co-Authors: Shivika Sharma, Subhankar Chatterjee
    Abstract:

    A psychrotolerant bacterium, isolated from Dhundi Glacier, Himachal Pradesh (India) was identified as Sphingobacterium kitahiroshimense LT-2 on the basis of biochemical, molecular and phylogenetic analysis. Sphingobacterium kitahiroshimense was first reported from Japan and was isolated from the city of Kitahiroshima, Hokkaido, Japan. In this report we have discussed about the origin of our strain and predicted that air masses and dust associated microbial cells transportation phenomena may be applicable for the origin of this species in this region. Enzymes and secondary metabolites secreted by the genus Sphingobacterium have enormous potentiality regarding their biotechnological Application. Preliminary study of our strain based on metabolic profiling through HPLC showed many new metabolites were secreted by the bacterium when grown in presence of different sugar medium at 28 °C. As far as our knowledge this is the first report about Sphingobacterium species isolated from this region. This preliminary finding will help to draw an idea about the bacterial population in this Himalayan Glaciers (in HP) as well as biotechnological Application of this strain can be explored further.

Piotr Religa - One of the best experts on this subject based on the ideXlab platform.

  • the Future Application of induced pluripotent stem cells in vascular regenerative medicine
    Cardiovascular Research, 2012
    Co-Authors: Piotr Religa
    Abstract:

    This editorial refers to ‘Functional vascular smooth muscle cells derived from human induced pluripotent stem cells via mesenchymal stem cell intermediates’ by V.K. Bajpai et al. , pp. 391–400, this issue. The transplantation of autologous stem cells is the gold standard for regenerative therapy, which includes both local transplantation of the cells to injured organs and the engineering of organs. The use of smooth muscle cells (SMCs) has been shown to improve cardiac, vascular, and respiratory function. SMCs in the vasculature mimic natural healing mechanisms.1 The important cells for vascular regenerative medicine are mesenchymal stromal cells.2 The sources of mesenchymal stem cells (MSCs) are well defined and include bone marrow, fat, amniotic fluid, umbilical cord, muscle-derived stem cells, and hair follicle-derived MSCs.3,4 The major problem with regenerative therapy remains the source of the cells. MSCs have limited proliferative potential that decreases with increasing donor age. Thus, finding new types of cells remains an important problem. Human induced pluripotent stem cells (iPSCs) are an interesting alternative to MSCs and embryonic stem cells. The iPSCs described in 2006 were of interest because they were collected from adult somatic cells and transformed into stem cells by the ectopic expression of factors, including Oct3/4, Sox2, and c-Myc. The cells have great differentiation potential, similar to embryonic stem cells, as shown by a number of rigorous tests. …

Alberto Leon-garcia - One of the best experts on this subject based on the ideXlab platform.

  • ICC Workshops - Software-defined infrastructure and the Future Central Office
    2013 IEEE International Conference on Communications Workshops (ICC), 2013
    Co-Authors: Joon-myung Kang, Hadi Bannazadeh, Mohammad Faraji, Hesam Rahimi, Thomas W. Lin, Alberto Leon-garcia
    Abstract:

    This paper discusses the role of virtualization and software-defined infrastructure (SDI) in the design of Future Application platforms, and in particular the Future Central Office (CO). A multi-tier computing cloud is presented in which resources in the Smart Edge of the network play a crucial role in the delivery of low-latency and data-intensive Applications. Resources in the Smart Edge are virtualized and managed using cloud computing principles, but these resources are more diverse than in conventional data centers, including programmable hardware, GPUs, etc. We propose an architecture for Future Application platforms, and we describe the SAVI Testbed (TB) design for the Smart Edge. The design features a novel Software-Defined Infrastructure manager that operates on top of OpenStack and OpenFlow. We conclude with a discussion of the implications of the Smart Edge design on the Future CO.

  • software defined infrastructure and the Future central office
    International Conference on Communications, 2013
    Co-Authors: Joon-myung Kang, Thomas Lin, Hadi Bannazadeh, Mohammad Faraji, Hesam Rahimi, Alberto Leon-garcia
    Abstract:

    This paper discusses the role of virtualization and software-defined infrastructure (SDI) in the design of Future Application platforms, and in particular the Future Central Office (CO). A multi-tier computing cloud is presented in which resources in the Smart Edge of the network play a crucial role in the delivery of low-latency and data-intensive Applications. Resources in the Smart Edge are virtualized and managed using cloud computing principles, but these resources are more diverse than in conventional data centers, including programmable hardware, GPUs, etc. We propose an architecture for Future Application platforms, and we describe the SAVI Testbed (TB) design for the Smart Edge. The design features a novel Software-Defined Infrastructure manager that operates on top of OpenStack and OpenFlow. We conclude with a discussion of the implications of the Smart Edge design on the Future CO.

  • software defined infrastructure and the Future central office
    International Conference on Communications, 2013
    Co-Authors: Joon-myung Kang, Thomas Lin, Hadi Bannazadeh, Mohammad Faraji, Hesam Rahimi, Alberto Leon-garcia
    Abstract:

    This paper discusses the role of virtualization and software-defined infrastructure (SDI) in the design of Future Application platforms, and in particular the Future Central Office (CO). A multi-tier computing cloud is presented in which resources in the Smart Edge of the network play a crucial role in the delivery of low-latency and data-intensive Applications. Resources in the Smart Edge are virtualized and managed using cloud computing principles, but these resources are more diverse than in conventional data centers, including programmable hardware, GPUs, etc. We propose an architecture for Future Application platforms, and we describe the SAVI Testbed (TB) design for the Smart Edge. The design features a novel Software-Defined Infrastructure manager that operates on top of OpenStack and OpenFlow. We conclude with a discussion of the implications of the Smart Edge design on the Future CO.

  • SOCA - On the Emergence of an Application-Oriented Network Architecture
    IEEE International Conference on Service-Oriented Computing and Applications (SOCA '07), 2007
    Co-Authors: Hadi Bannazadeh, Alberto Leon-garcia
    Abstract:

    There is much debate today on what should be the architecture of the next generation of networks. In this paper, we address this question from the perspective of Applications. We examine current and emerging Applications to identify the factors that lead to a successful deployment. In addition to new computing models, we also examine trends in the mainstream information technology and telecom service provider industry, namely, Service Oriented Architecture and IP Multimedia Subsystem. We identify requirements of, and then present some views on what constitutes the Future Application-oriented networks architecture, and finally we propose a new model for Future Application-oriented networks and we discuss the research challenges.

Shivika Sharma - One of the best experts on this subject based on the ideXlab platform.

  • Psychrotolerant Sphingobacterium kitahiroshimense LT-2 Isolated from Dhundi Glacier, Himachal Pradesh: Origin Prediction and Future Application.
    Indian Journal of Microbiology, 2018
    Co-Authors: Shivika Sharma, Subhankar Chatterjee
    Abstract:

    A psychrotolerant bacterium, isolated from Dhundi Glacier, Himachal Pradesh (India) was identified as Sphingobacterium kitahiroshimense LT-2 on the basis of biochemical, molecular and phylogenetic analysis. Sphingobacterium kitahiroshimense was first reported from Japan and was isolated from the city of Kitahiroshima, Hokkaido, Japan. In this report we have discussed about the origin of our strain and predicted that air masses and dust associated microbial cells transportation phenomena may be applicable for the origin of this species in this region. Enzymes and secondary metabolites secreted by the genus Sphingobacterium have enormous potentiality regarding their biotechnological Application. Preliminary study of our strain based on metabolic profiling through HPLC showed many new metabolites were secreted by the bacterium when grown in presence of different sugar medium at 28 °C. As far as our knowledge this is the first report about Sphingobacterium species isolated from this region. This preliminary finding will help to draw an idea about the bacterial population in this Himalayan Glaciers (in HP) as well as biotechnological Application of this strain can be explored further.

  • Psychrotolerant Sphingobacterium kitahiroshimense LT-2 Isolated from Dhundi Glacier, Himachal Pradesh: Origin Prediction and Future Application.
    Indian Journal of Microbiology, 2018
    Co-Authors: Shivika Sharma, Subhankar Chatterjee
    Abstract:

    A psychrotolerant bacterium, isolated from Dhundi Glacier, Himachal Pradesh (India) was identified as Sphingobacterium kitahiroshimense LT-2 on the basis of biochemical, molecular and phylogenetic analysis. Sphingobacterium kitahiroshimense was first reported from Japan and was isolated from the city of Kitahiroshima, Hokkaido, Japan. In this report we have discussed about the origin of our strain and predicted that air masses and dust associated microbial cells transportation phenomena may be applicable for the origin of this species in this region. Enzymes and secondary metabolites secreted by the genus Sphingobacterium have enormous potentiality regarding their biotechnological Application. Preliminary study of our strain based on metabolic profiling through HPLC showed many new metabolites were secreted by the bacterium when grown in presence of different sugar medium at 28 °C. As far as our knowledge this is the first report about Sphingobacterium species isolated from this region. This preliminary finding will help to draw an idea about the bacterial population in this Himalayan Glaciers (in HP) as well as biotechnological Application of this strain can be explored further.

Andrzej Marszałek - One of the best experts on this subject based on the ideXlab platform.

  • New Amniotic Membrane Based Biocomposite for Future Application in Reconstructive Urology
    PloS one, 2016
    Co-Authors: Jan Adamowicz, Marta Pokrywczynska, Shane Vontelin Van Breda, Dominik Tyloch, J. Tworkiewicz, Tomasz Kowalczyk, Tomasz Kloskowski, Magda Bodnar, J. Skopinska-wisniewska, Andrzej Marszałek
    Abstract:

    Objective Due to the capacity of the amniotic membrane (Am) to support re-epithelisation and inhibit scar formation, Am has a potential to become a considerable asset for reconstructive urology i.e., reconstruction of ureters and urethrae. The Application of Am in reconstructive urology is limited due to a poor mechanical characteristic. Am reinforcement with electrospun nanofibers offers a new strategy to improve Am mechanical resistance, without affecting its unique bioactivity profile. This study evaluated biocomposite material composed of Am and nanofibers as a graft for urinary bladder augmentation in a rat model. Material and Methods Sandwich-structured biocomposite material was constructed from frozen Am and covered on both sides with two-layered membranes prepared from electrospun poly-(L-lactide-co-E-caprolactone) (PLCL). Wistar rats underwent hemicystectomy and bladder augmentation with the biocomposite material. Results Immunohistohemical analysis (hematoxylin and eosin [H&E], anti-smoothelin and Masson’s trichrome staining [TRI]) revealed effective regeneration of the urothelial and smooth muscle layers. Anti-smoothelin staining confirmed the presence of contractile smooth muscle within a new bladder wall. Sandwich-structured biocomposite graft material was designed to regenerate the urinary bladder wall, fulfilling the requirements for normal bladder tension, contraction, elasticity and compliance. Mechanical evaluation of regenerated bladder wall conducted based on Young’s elastic modulus reflected changes in the histological remodeling of the augmented part of the bladder. The structure of the biocomposite material made it possible to deliver an intact Am to the area for regeneration. An unmodified Am surface supported regeneration of the urinary bladder wall and the PLCL membranes did not disturb the regeneration process. Conclusions Am reinforcement with electrospun nanofibers offers a new strategy to improve Am mechanical resistance without affecting its unique bioactivity profile.