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Y Yamada - One of the best experts on this subject based on the ideXlab platform.

  • present status and Future Prospect of coated conductor development and its application in japan
    Superconductor Science and Technology, 2008
    Co-Authors: Y Shiohara, M Yoshizumi, T Izumi, Y Yamada
    Abstract:

    The current national project on coated conductors using Y-system superconductors has been carried out over the project period (FY2003–FY2007). In this paper, the current status and the Future Prospect of this project are reviewed. The high performance tape development group, consisting of Fujikura and SRL-NCCC, has worked on the tape by PLD-REBCO superconducting layers on PLD-CeO2/IBAD-GZO buffered substrates. A high product of Ic and L, higher than 112 166 A m, was achieved in a 368 m–304.8 A GdBCO tape whose Ic value is mostly above 350 A/cm in width. The performance under magnetic field was also improved up to 42 A at 3 T in a GdBCO short film with doping of ZrO2. 61 m long GdBCO tape with ZrO2 doping showed a high Ic value of 220 A at self field and 30 A at 3 T. On the other hand, another group focusing on low production cost has worked on TFA-MOD and MOCVD processes. The extremely high Ic value of 735 A/cm-w was obtained in TFA-MOD films on PLD-CeO2/IBAD-GZO/Hastelloy substrate due to the effect of Ba-poor nominal composition. In efforts towards long tape production by the SWCC group, a 200 m long tape with a high Ic value of 200 A/cm-w was obtained using a batch-type furnace. The Ic × L value of this tape was 40 000 A m, which is the highest value in the world obtained by the TFA-MOD process. Based on the above achievements in coated conductor process development, two new additional goals were set in the project. One is the development of extremely low cost tape and the other is the development of the basic technologies for making electric power devices of cables, transformers, motors, current-limiters and cryocoolers. Some of the new investigations have already revealed marvellous results, such as a 15 kW motor, low AC loss coils, low AC loss cables, etc.

K Park - One of the best experts on this subject based on the ideXlab platform.

  • oral protein delivery current status and Future Prospect
    Reactive & Functional Polymers, 2011
    Co-Authors: K Park, Ick Chan Kwon
    Abstract:

    Advances in biotechnology have produced therapeutically active proteins on a commercial scale, and therapeutic proteins are now extensively applied in medical practices to treat various diseases. Oral delivery of protein drugs is a highly attractive approach, and, naturally, numerous attempts have been made to develop such formulations. Despite various attempts, however, no clinically useful oral formulations have been developed, and this is mainly due to extremely low bioavailability of protein drugs. The effective oral protein delivery needs to overcome barriers related to poor absorption, poor permeation, and degradation in the gastrointestinal tract. Various strategies have been explored for enhancing the bioavailability of orally administered proteins. They include chemical modification of protein drugs, use of enzyme inhibitors, and exploration of special formulation ingredients, such as absorption enhancers and mucoadhesive polymers. This article examines the current technologies under development for oral protein delivery.

Y Shiohara - One of the best experts on this subject based on the ideXlab platform.

  • present status and Future Prospect of coated conductor development and its application in japan
    Superconductor Science and Technology, 2008
    Co-Authors: Y Shiohara, M Yoshizumi, T Izumi, Y Yamada
    Abstract:

    The current national project on coated conductors using Y-system superconductors has been carried out over the project period (FY2003–FY2007). In this paper, the current status and the Future Prospect of this project are reviewed. The high performance tape development group, consisting of Fujikura and SRL-NCCC, has worked on the tape by PLD-REBCO superconducting layers on PLD-CeO2/IBAD-GZO buffered substrates. A high product of Ic and L, higher than 112 166 A m, was achieved in a 368 m–304.8 A GdBCO tape whose Ic value is mostly above 350 A/cm in width. The performance under magnetic field was also improved up to 42 A at 3 T in a GdBCO short film with doping of ZrO2. 61 m long GdBCO tape with ZrO2 doping showed a high Ic value of 220 A at self field and 30 A at 3 T. On the other hand, another group focusing on low production cost has worked on TFA-MOD and MOCVD processes. The extremely high Ic value of 735 A/cm-w was obtained in TFA-MOD films on PLD-CeO2/IBAD-GZO/Hastelloy substrate due to the effect of Ba-poor nominal composition. In efforts towards long tape production by the SWCC group, a 200 m long tape with a high Ic value of 200 A/cm-w was obtained using a batch-type furnace. The Ic × L value of this tape was 40 000 A m, which is the highest value in the world obtained by the TFA-MOD process. Based on the above achievements in coated conductor process development, two new additional goals were set in the project. One is the development of extremely low cost tape and the other is the development of the basic technologies for making electric power devices of cables, transformers, motors, current-limiters and cryocoolers. Some of the new investigations have already revealed marvellous results, such as a 15 kW motor, low AC loss coils, low AC loss cables, etc.

David G Mutch - One of the best experts on this subject based on the ideXlab platform.

  • targeted endometrial cancer therapy as a Future Prospect
    Women's Health, 2013
    Co-Authors: Duangmani Thanapprapasr, Chalong Cheewakriangkrai, Puchong Likittanasombut, Kamolrat Thanapprapasr, David G Mutch
    Abstract:

    Among female-specific cancers worldwide, endometrial cancer is the third most common after breast cancer and cervical cancer. In addition, it is the most common gynecological cancer in the USA and Europe. The incidence of this disease appears to be increasing. The cause of this increase is multifactorial, but a few possible factors involved are increasing obesity, an aging population leading to more postmenopausal women and greater tamoxifen use. Surgery is generally the primary treatment of this disease and postoperative radiation therapy in some patients with high or intermediate risk may prevent locoregional recurrences. Adjuvant chemotherapy improves progression-free survival in advanced or recurrent cancer. However, overall survival in patients with advanced disease is poor. Hence, better therapy is needed and targeted molecular therapies are emerging as possible treatment candidates. These include molecules that target VEGF, mTOR, tyrosine kinases, human EGF receptors and FGF receptors. Therapies ta...

Ibrahim Yuksel - One of the best experts on this subject based on the ideXlab platform.

  • Present Situation and Future Prospect of Energy Utilization and Climate Change in Turkey
    New Developments in Renewable Energy, 2013
    Co-Authors: Ibrahim Yuksel, Kamil Kaygusuz, Hasan Arman
    Abstract:

    Turkey is heavily dependent onexpensive imported energy resources that place a big burden on the economy andair pollution is becoming a great environmental concern in the country. Themajor cities of western Turkey are cosmopolitan centers of industry, financeand trade, whereas the eastern part of the country is relativelyunderdeveloped. Turkey’s high rate of energy-related carbon emissions growth isexpected to accelerate, with emissions climbing from 57 million tons in 2000 toalmost 210 million tons in 2020. Carbon intensity in Turkey is higher than thewestern developed nation average. In this regard, renewable energy resourcesappear to be the one of the most efficient and effective solutions for cleanand sustainable energy development in Turkey. More generally, climate changeand sustainable development interact in a circular fashion. Climate changevulnerability, impacts and adaptation will influence Prospects for sustainabledevelopment, and in turn, alternative development paths will not only determinegreenhouse gas emission levels that affect Future climate change, but alsoinfluence Future capacity to adapt to and mitigate climate change. The key toan effective climate change response strategy is a better understanding ofrelevant policy linkages. Development planners, naturally, place developmentfirst, and therefore, climate policies need to be integrated within nationalsustainable development strategies. In particular, they would like to knowwhether specific climate change impacts and response measures will makeexisting development efforts less, or more, sustainable in terms of theireconomic, social and environmental dimensions. However, developing theremaining hydropower potential offers many challenges and pressures from someenvironmental action groups over its impact has tended to increase over time.Hydropower throughout the world provides 17% of our electricity from aninstalled capacity of some 730 GW is currently under construction, makinghydropower by far the most important renewable energy for electrical powerproduction. The contribution of hydropower, especially small hydropower to theworldwide electrical capacity is more of a similar scale to the other renewableenergy sources amounting to about 47 GW of this capacity is in developingcountries. The share of renewables in total electricity generation is 17%, whilethat of thermal is 80% in 2009. The projection for the period 2010-2020 is forannual growth of 8% in total electricity generation. The additional generationcapacity needed up to 2020 will require huge investments. Electricity supplyinfrastructure in Turkey is being rapidly extended, as policymakers andinvestors increasingly recognize the essential role of energy in improvingliving standards and sustaining economic growth. This paper deals with presentsituation and Future Prospect of energy utilization for improving renewable energy in Turkey.

  • Renewable energy status of electricity generation and Future Prospect hydropower in Turkey
    Renewable Energy, 2013
    Co-Authors: Ibrahim Yuksel
    Abstract:

    In the last decade, Turkish electricity demand has increased more than 8% per annum as a result of economic development. Being one of the renewable energy sources par excellence, non-exhaustible, non-polluting and economically more attractive than other renewable sources, hydropower has turned out to be an important contributor to the Future energy mix of the country. Turkey's renewable energy sources especially hydropower sources are plentiful and extensive, and represent the second-largest domestic energy sources after coal. Turkey has a total gross hydropower potential of 433 TWh/year and 140 TWh/year of this capacity can be used economically. Currently, Turkey has 172 hydroelectric power plants in operation with total installed capacity of 13,700 MW generating an average of 48,000 GWh/year, which is 35% of the economically viable hydroelectric potential. 148 hydroelectric power plants are under construction 8,600 MW of installed capacity to generate average annual 20,000 GWh representing 14% of the economically viable potential. The share of renewables in total electricity generation is 17%, while that of thermal is 80% in 2009. The projection for the period 2010–2020 is for annual growth of 8% in total electricity generation. The additional generation capacity needed up to 2020 will require huge investments. This paper deals with present situation and Future Prospect of renewable energy and the role of hydropower in Turkey.