The Experts below are selected from a list of 273 Experts worldwide ranked by ideXlab platform
Hiroki Koyama - One of the best experts on this subject based on the ideXlab platform.
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Usefulness of a solid-state Gamma Camera for sentinel node identification in patients with breast cancer.
Journal of surgical oncology, 2005Co-Authors: Kazuyoshi Motomura, Atsushi Noguchi, Terumi Hashizume, Yoshihisa Hasegawa, Yoshifumi Komoike, Hideo Inaji, Toshihide Saida, Hiroki KoyamaAbstract:Background A solid-state Gamma Camera was recently developed. This tool may enable intra-operative imaging of sentinel nodes in breast cancer. The aim of the present study was to evaluate the usefulness of a solid-state Gamma Camera for the pre- and intra-operative identification of sentinel nodes in patients with breast cancer. Methods Breast cancer patients with clinically negative nodes underwent sentinel node biopsy using dye and radioisotopes. Lymphoscintigraphy using both the conventional Anger Camera and the solid-state Gamma Camera was performed the day before surgery. Sentinel nodes were intra-operatively identified using the Gamma probe and imaged with a solid-state Gamma Camera, and then excised. When several sentinel nodes were present, these steps were repeated. Results Twenty-nine patients (30 basins) were enrolled in the study. The mean patient age was 54 years and the mean tumor size was 16 mm. A total of 41 sentinel nodes were identified using the Anger Camera or the solid-state Gamma Camera pre-operatively. Thirty-eight sentinel nodes (92.7%) were identified using both the Anger Camera and the solid-state Gamma Camera, 1 sentinel node (2.4%) was identified using the Anger Camera alone, and 2 sentinel nodes (4.9%) were identified using the solid-state Gamma Camera alone. A total of 63 sentinel nodes were identified using the Gamma probe or the solid-state Gamma Camera intra-operatively, and were excised. Fifty-seven sentinel nodes (90.5%) were identified using both the Gamma probe and the solid-state Gamma Camera, 3 sentinel nodes (4.8%) were identified using the Gamma probe alone, and 3 sentinel nodes (4.8%) were identified using the solid-state Gamma Camera alone. Conclusions The solid-state Gamma Camera is useful for pre- and intra-operative identification of sentinel nodes in breast cancer. The significance of the solid-state Gamma Camera could be that it compensates for the Gamma probe when the Gamma probe cannot identify some sentinel nodes because of the shine through effect, and avoids leaving the residual sentinel nodes behind the axilla intra-operatively. J. Surg. Oncol. 2005;89:12–17. © 2004 Wiley-Liss, Inc.
Kazuyoshi Motomura - One of the best experts on this subject based on the ideXlab platform.
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Usefulness of a solid-state Gamma Camera for sentinel node identification in patients with breast cancer.
Journal of surgical oncology, 2005Co-Authors: Kazuyoshi Motomura, Atsushi Noguchi, Terumi Hashizume, Yoshihisa Hasegawa, Yoshifumi Komoike, Hideo Inaji, Toshihide Saida, Hiroki KoyamaAbstract:Background A solid-state Gamma Camera was recently developed. This tool may enable intra-operative imaging of sentinel nodes in breast cancer. The aim of the present study was to evaluate the usefulness of a solid-state Gamma Camera for the pre- and intra-operative identification of sentinel nodes in patients with breast cancer. Methods Breast cancer patients with clinically negative nodes underwent sentinel node biopsy using dye and radioisotopes. Lymphoscintigraphy using both the conventional Anger Camera and the solid-state Gamma Camera was performed the day before surgery. Sentinel nodes were intra-operatively identified using the Gamma probe and imaged with a solid-state Gamma Camera, and then excised. When several sentinel nodes were present, these steps were repeated. Results Twenty-nine patients (30 basins) were enrolled in the study. The mean patient age was 54 years and the mean tumor size was 16 mm. A total of 41 sentinel nodes were identified using the Anger Camera or the solid-state Gamma Camera pre-operatively. Thirty-eight sentinel nodes (92.7%) were identified using both the Anger Camera and the solid-state Gamma Camera, 1 sentinel node (2.4%) was identified using the Anger Camera alone, and 2 sentinel nodes (4.9%) were identified using the solid-state Gamma Camera alone. A total of 63 sentinel nodes were identified using the Gamma probe or the solid-state Gamma Camera intra-operatively, and were excised. Fifty-seven sentinel nodes (90.5%) were identified using both the Gamma probe and the solid-state Gamma Camera, 3 sentinel nodes (4.8%) were identified using the Gamma probe alone, and 3 sentinel nodes (4.8%) were identified using the solid-state Gamma Camera alone. Conclusions The solid-state Gamma Camera is useful for pre- and intra-operative identification of sentinel nodes in breast cancer. The significance of the solid-state Gamma Camera could be that it compensates for the Gamma probe when the Gamma probe cannot identify some sentinel nodes because of the shine through effect, and avoids leaving the residual sentinel nodes behind the axilla intra-operatively. J. Surg. Oncol. 2005;89:12–17. © 2004 Wiley-Liss, Inc.
Lenka Vermeeren - One of the best experts on this subject based on the ideXlab platform.
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The use of a portable Gamma Camera for preoperative lymphatic mapping: a comparison with a conventional Gamma Camera.
European journal of nuclear medicine and molecular imaging, 2010Co-Authors: Sergi Vidal-sicart, Lenka Vermeeren, Oriol Solà, Pilar Paredes, Renato A. Valdés-olmosAbstract:Purpose Planar lymphoscintigraphy is routinely used for preoperative sentinel node visualization, but large Gamma Cameras are not always available. We evaluated the reproducibility of lymphatic mapping with a smaller and portable Gamma Camera.
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a portable Gamma Camera for intraoperative detection of sentinel nodes in the head and neck region
The Journal of Nuclear Medicine, 2010Co-Authors: Lenka Vermeeren, Renato Valdes A Olmos, Martin W C Klop, Alfons J M Balm, Michiel W M Van Den BrekelAbstract:UNLABELLED: We introduced and evaluated a portable Gamma-Camera for intraoperative visualization of sentinel nodes in the head and neck region. METHODS: Planar lymphoscintigraphy and SPECT/CT were performed after peritumoral injection of (99m)Tc-nanocolloid in 25 patients (head and neck melanoma or oral cavity carcinoma). Sentinel nodes were localized intraoperatively with a portable Gamma-Camera and a hand-held Gamma-probe. The portable Gamma-Camera was used to determine the distribution of remaining radioactivity after excision of the sentinel nodes. RESULTS: The portable Gamma-Camera visualized all 70 preoperatively identified sentinel nodes. Sentinel nodes at difficult sites could be localized more efficiently, and in 6 patients, 9 additional nodes (1 tumor-positive) were identified with the portable Gamma-Camera after excision. CONCLUSION: Intraoperative identification of sentinel nodes in the head and neck region with a portable Gamma-Camera is feasible and might lead to detection of more sentinel nodes.
Michiel W M Van Den Brekel - One of the best experts on this subject based on the ideXlab platform.
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a portable Gamma Camera for intraoperative detection of sentinel nodes in the head and neck region
The Journal of Nuclear Medicine, 2010Co-Authors: Lenka Vermeeren, Renato Valdes A Olmos, Martin W C Klop, Alfons J M Balm, Michiel W M Van Den BrekelAbstract:UNLABELLED: We introduced and evaluated a portable Gamma-Camera for intraoperative visualization of sentinel nodes in the head and neck region. METHODS: Planar lymphoscintigraphy and SPECT/CT were performed after peritumoral injection of (99m)Tc-nanocolloid in 25 patients (head and neck melanoma or oral cavity carcinoma). Sentinel nodes were localized intraoperatively with a portable Gamma-Camera and a hand-held Gamma-probe. The portable Gamma-Camera was used to determine the distribution of remaining radioactivity after excision of the sentinel nodes. RESULTS: The portable Gamma-Camera visualized all 70 preoperatively identified sentinel nodes. Sentinel nodes at difficult sites could be localized more efficiently, and in 6 patients, 9 additional nodes (1 tumor-positive) were identified with the portable Gamma-Camera after excision. CONCLUSION: Intraoperative identification of sentinel nodes in the head and neck region with a portable Gamma-Camera is feasible and might lead to detection of more sentinel nodes.
Atsushi Noguchi - One of the best experts on this subject based on the ideXlab platform.
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Usefulness of a solid-state Gamma Camera for sentinel node identification in patients with breast cancer.
Journal of surgical oncology, 2005Co-Authors: Kazuyoshi Motomura, Atsushi Noguchi, Terumi Hashizume, Yoshihisa Hasegawa, Yoshifumi Komoike, Hideo Inaji, Toshihide Saida, Hiroki KoyamaAbstract:Background A solid-state Gamma Camera was recently developed. This tool may enable intra-operative imaging of sentinel nodes in breast cancer. The aim of the present study was to evaluate the usefulness of a solid-state Gamma Camera for the pre- and intra-operative identification of sentinel nodes in patients with breast cancer. Methods Breast cancer patients with clinically negative nodes underwent sentinel node biopsy using dye and radioisotopes. Lymphoscintigraphy using both the conventional Anger Camera and the solid-state Gamma Camera was performed the day before surgery. Sentinel nodes were intra-operatively identified using the Gamma probe and imaged with a solid-state Gamma Camera, and then excised. When several sentinel nodes were present, these steps were repeated. Results Twenty-nine patients (30 basins) were enrolled in the study. The mean patient age was 54 years and the mean tumor size was 16 mm. A total of 41 sentinel nodes were identified using the Anger Camera or the solid-state Gamma Camera pre-operatively. Thirty-eight sentinel nodes (92.7%) were identified using both the Anger Camera and the solid-state Gamma Camera, 1 sentinel node (2.4%) was identified using the Anger Camera alone, and 2 sentinel nodes (4.9%) were identified using the solid-state Gamma Camera alone. A total of 63 sentinel nodes were identified using the Gamma probe or the solid-state Gamma Camera intra-operatively, and were excised. Fifty-seven sentinel nodes (90.5%) were identified using both the Gamma probe and the solid-state Gamma Camera, 3 sentinel nodes (4.8%) were identified using the Gamma probe alone, and 3 sentinel nodes (4.8%) were identified using the solid-state Gamma Camera alone. Conclusions The solid-state Gamma Camera is useful for pre- and intra-operative identification of sentinel nodes in breast cancer. The significance of the solid-state Gamma Camera could be that it compensates for the Gamma probe when the Gamma probe cannot identify some sentinel nodes because of the shine through effect, and avoids leaving the residual sentinel nodes behind the axilla intra-operatively. J. Surg. Oncol. 2005;89:12–17. © 2004 Wiley-Liss, Inc.
