The Experts below are selected from a list of 1791 Experts worldwide ranked by ideXlab platform
Shaozong Chen - One of the best experts on this subject based on the ideXlab platform.
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treatment of infected soft tissue blast injury in swine by regulated negative pressure wound therapy
Annals of Surgery, 2013Co-Authors: Jinqing Li, Morris Topaz, Yuejun Li, Wangzhou Li, Yanqin Yuan, Shaozong Chen, Xueyong LiAbstract:This study was designed to investigate the therapeutic potential of regulated negative pressure wound therapy (RNPT) in treating infected blast injuries in swine. Approximately 30% to 80% of blast injuries develop infection, which increases the morbidity and mortality of these casualties. RNPT has been used in US military operations in Iraq; however, no randomized controlled study has been conducted on the use of RNPT to treat infected war injuries. Infected soft tissue blast injuries were treated with Gauze Dressings or RNPT with different pressures ranging from −5 to −35 kPa. To evaluate the wound healing process, the wound area, wound depth, the number of proliferative cells, and the vascular endothelial cells in the granulation tissue were measured at different time points. Furthermore, to evaluate the infection and inflammation of the blast injury, the bacterial load, bacterial species, and several inflammatory markers were detected. Compared with Gauze Dressing treatments, RNPT reduced bacterial load more efficiently, initiated granulation tissue formation earlier, and increased the inflammation faster. Negative pressures ranging from −10 to −25 kPa applied on the RNPT group showed beneficial effects in treating the infected soft tissue blast injury. RNPT did not significantly change both the aerobic and anaerobic bacterial composition compared with those of the Gauze Dressing group. RNPT clearly shows beneficial effects in treating the infected soft tissue blast injury in comparison with the Gauze Dressing therapy in swine.
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treatment of infected soft tissue blast injury in swine by regulated negative pressure wound therapy
Annals of Surgery, 2013Co-Authors: Morris Topaz, Yanqin Yuan, Hong Tan, Wenxing Xun, Shaozong ChenAbstract:OBJECTIVE This study was designed to investigate the therapeutic potential of regulated negative pressure wound therapy (RNPT) in treating infected blast injuries in swine. BACKGROUND Approximately 30% to 80% of blast injuries develop infection, which increases the morbidity and mortality of these casualties. RNPT has been used in US military operations in Iraq; however, no randomized controlled study has been conducted on the use of RNPT to treat infected war injuries. METHODS Infected soft tissue blast injuries were treated with Gauze Dressings or RNPT with different pressures ranging from -5 to -35 kPa. To evaluate the wound healing process, the wound area, wound depth, the number of proliferative cells, and the vascular endothelial cells in the granulation tissue were measured at different time points. Furthermore, to evaluate the infection and inflammation of the blast injury, the bacterial load, bacterial species, and several inflammatory markers were detected. RESULTS Compared with Gauze Dressing treatments, RNPT reduced bacterial load more efficiently, initiated granulation tissue formation earlier, and increased the inflammation faster. Negative pressures ranging from -10 to -25 kPa applied on the RNPT group showed beneficial effects in treating the infected soft tissue blast injury. RNPT did not significantly change both the aerobic and anaerobic bacterial composition compared with those of the Gauze Dressing group. CONCLUSIONS RNPT clearly shows beneficial effects in treating the infected soft tissue blast injury in comparison with the Gauze Dressing therapy in swine.
Morris Topaz - One of the best experts on this subject based on the ideXlab platform.
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treatment of infected soft tissue blast injury in swine by regulated negative pressure wound therapy
Annals of Surgery, 2013Co-Authors: Jinqing Li, Morris Topaz, Yuejun Li, Wangzhou Li, Yanqin Yuan, Shaozong Chen, Xueyong LiAbstract:This study was designed to investigate the therapeutic potential of regulated negative pressure wound therapy (RNPT) in treating infected blast injuries in swine. Approximately 30% to 80% of blast injuries develop infection, which increases the morbidity and mortality of these casualties. RNPT has been used in US military operations in Iraq; however, no randomized controlled study has been conducted on the use of RNPT to treat infected war injuries. Infected soft tissue blast injuries were treated with Gauze Dressings or RNPT with different pressures ranging from −5 to −35 kPa. To evaluate the wound healing process, the wound area, wound depth, the number of proliferative cells, and the vascular endothelial cells in the granulation tissue were measured at different time points. Furthermore, to evaluate the infection and inflammation of the blast injury, the bacterial load, bacterial species, and several inflammatory markers were detected. Compared with Gauze Dressing treatments, RNPT reduced bacterial load more efficiently, initiated granulation tissue formation earlier, and increased the inflammation faster. Negative pressures ranging from −10 to −25 kPa applied on the RNPT group showed beneficial effects in treating the infected soft tissue blast injury. RNPT did not significantly change both the aerobic and anaerobic bacterial composition compared with those of the Gauze Dressing group. RNPT clearly shows beneficial effects in treating the infected soft tissue blast injury in comparison with the Gauze Dressing therapy in swine.
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treatment of infected soft tissue blast injury in swine by regulated negative pressure wound therapy
Annals of Surgery, 2013Co-Authors: Morris Topaz, Yanqin Yuan, Hong Tan, Wenxing Xun, Shaozong ChenAbstract:OBJECTIVE This study was designed to investigate the therapeutic potential of regulated negative pressure wound therapy (RNPT) in treating infected blast injuries in swine. BACKGROUND Approximately 30% to 80% of blast injuries develop infection, which increases the morbidity and mortality of these casualties. RNPT has been used in US military operations in Iraq; however, no randomized controlled study has been conducted on the use of RNPT to treat infected war injuries. METHODS Infected soft tissue blast injuries were treated with Gauze Dressings or RNPT with different pressures ranging from -5 to -35 kPa. To evaluate the wound healing process, the wound area, wound depth, the number of proliferative cells, and the vascular endothelial cells in the granulation tissue were measured at different time points. Furthermore, to evaluate the infection and inflammation of the blast injury, the bacterial load, bacterial species, and several inflammatory markers were detected. RESULTS Compared with Gauze Dressing treatments, RNPT reduced bacterial load more efficiently, initiated granulation tissue formation earlier, and increased the inflammation faster. Negative pressures ranging from -10 to -25 kPa applied on the RNPT group showed beneficial effects in treating the infected soft tissue blast injury. RNPT did not significantly change both the aerobic and anaerobic bacterial composition compared with those of the Gauze Dressing group. CONCLUSIONS RNPT clearly shows beneficial effects in treating the infected soft tissue blast injury in comparison with the Gauze Dressing therapy in swine.
Xueyong Li - One of the best experts on this subject based on the ideXlab platform.
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treatment of infected soft tissue blast injury in swine by regulated negative pressure wound therapy
Annals of Surgery, 2013Co-Authors: Jinqing Li, Morris Topaz, Yuejun Li, Wangzhou Li, Yanqin Yuan, Shaozong Chen, Xueyong LiAbstract:This study was designed to investigate the therapeutic potential of regulated negative pressure wound therapy (RNPT) in treating infected blast injuries in swine. Approximately 30% to 80% of blast injuries develop infection, which increases the morbidity and mortality of these casualties. RNPT has been used in US military operations in Iraq; however, no randomized controlled study has been conducted on the use of RNPT to treat infected war injuries. Infected soft tissue blast injuries were treated with Gauze Dressings or RNPT with different pressures ranging from −5 to −35 kPa. To evaluate the wound healing process, the wound area, wound depth, the number of proliferative cells, and the vascular endothelial cells in the granulation tissue were measured at different time points. Furthermore, to evaluate the infection and inflammation of the blast injury, the bacterial load, bacterial species, and several inflammatory markers were detected. Compared with Gauze Dressing treatments, RNPT reduced bacterial load more efficiently, initiated granulation tissue formation earlier, and increased the inflammation faster. Negative pressures ranging from −10 to −25 kPa applied on the RNPT group showed beneficial effects in treating the infected soft tissue blast injury. RNPT did not significantly change both the aerobic and anaerobic bacterial composition compared with those of the Gauze Dressing group. RNPT clearly shows beneficial effects in treating the infected soft tissue blast injury in comparison with the Gauze Dressing therapy in swine.
Yanqin Yuan - One of the best experts on this subject based on the ideXlab platform.
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treatment of infected soft tissue blast injury in swine by regulated negative pressure wound therapy
Annals of Surgery, 2013Co-Authors: Jinqing Li, Morris Topaz, Yuejun Li, Wangzhou Li, Yanqin Yuan, Shaozong Chen, Xueyong LiAbstract:This study was designed to investigate the therapeutic potential of regulated negative pressure wound therapy (RNPT) in treating infected blast injuries in swine. Approximately 30% to 80% of blast injuries develop infection, which increases the morbidity and mortality of these casualties. RNPT has been used in US military operations in Iraq; however, no randomized controlled study has been conducted on the use of RNPT to treat infected war injuries. Infected soft tissue blast injuries were treated with Gauze Dressings or RNPT with different pressures ranging from −5 to −35 kPa. To evaluate the wound healing process, the wound area, wound depth, the number of proliferative cells, and the vascular endothelial cells in the granulation tissue were measured at different time points. Furthermore, to evaluate the infection and inflammation of the blast injury, the bacterial load, bacterial species, and several inflammatory markers were detected. Compared with Gauze Dressing treatments, RNPT reduced bacterial load more efficiently, initiated granulation tissue formation earlier, and increased the inflammation faster. Negative pressures ranging from −10 to −25 kPa applied on the RNPT group showed beneficial effects in treating the infected soft tissue blast injury. RNPT did not significantly change both the aerobic and anaerobic bacterial composition compared with those of the Gauze Dressing group. RNPT clearly shows beneficial effects in treating the infected soft tissue blast injury in comparison with the Gauze Dressing therapy in swine.
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treatment of infected soft tissue blast injury in swine by regulated negative pressure wound therapy
Annals of Surgery, 2013Co-Authors: Morris Topaz, Yanqin Yuan, Hong Tan, Wenxing Xun, Shaozong ChenAbstract:OBJECTIVE This study was designed to investigate the therapeutic potential of regulated negative pressure wound therapy (RNPT) in treating infected blast injuries in swine. BACKGROUND Approximately 30% to 80% of blast injuries develop infection, which increases the morbidity and mortality of these casualties. RNPT has been used in US military operations in Iraq; however, no randomized controlled study has been conducted on the use of RNPT to treat infected war injuries. METHODS Infected soft tissue blast injuries were treated with Gauze Dressings or RNPT with different pressures ranging from -5 to -35 kPa. To evaluate the wound healing process, the wound area, wound depth, the number of proliferative cells, and the vascular endothelial cells in the granulation tissue were measured at different time points. Furthermore, to evaluate the infection and inflammation of the blast injury, the bacterial load, bacterial species, and several inflammatory markers were detected. RESULTS Compared with Gauze Dressing treatments, RNPT reduced bacterial load more efficiently, initiated granulation tissue formation earlier, and increased the inflammation faster. Negative pressures ranging from -10 to -25 kPa applied on the RNPT group showed beneficial effects in treating the infected soft tissue blast injury. RNPT did not significantly change both the aerobic and anaerobic bacterial composition compared with those of the Gauze Dressing group. CONCLUSIONS RNPT clearly shows beneficial effects in treating the infected soft tissue blast injury in comparison with the Gauze Dressing therapy in swine.
Jinqing Li - One of the best experts on this subject based on the ideXlab platform.
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treatment of infected soft tissue blast injury in swine by regulated negative pressure wound therapy
Annals of Surgery, 2013Co-Authors: Jinqing Li, Morris Topaz, Yuejun Li, Wangzhou Li, Yanqin Yuan, Shaozong Chen, Xueyong LiAbstract:This study was designed to investigate the therapeutic potential of regulated negative pressure wound therapy (RNPT) in treating infected blast injuries in swine. Approximately 30% to 80% of blast injuries develop infection, which increases the morbidity and mortality of these casualties. RNPT has been used in US military operations in Iraq; however, no randomized controlled study has been conducted on the use of RNPT to treat infected war injuries. Infected soft tissue blast injuries were treated with Gauze Dressings or RNPT with different pressures ranging from −5 to −35 kPa. To evaluate the wound healing process, the wound area, wound depth, the number of proliferative cells, and the vascular endothelial cells in the granulation tissue were measured at different time points. Furthermore, to evaluate the infection and inflammation of the blast injury, the bacterial load, bacterial species, and several inflammatory markers were detected. Compared with Gauze Dressing treatments, RNPT reduced bacterial load more efficiently, initiated granulation tissue formation earlier, and increased the inflammation faster. Negative pressures ranging from −10 to −25 kPa applied on the RNPT group showed beneficial effects in treating the infected soft tissue blast injury. RNPT did not significantly change both the aerobic and anaerobic bacterial composition compared with those of the Gauze Dressing group. RNPT clearly shows beneficial effects in treating the infected soft tissue blast injury in comparison with the Gauze Dressing therapy in swine.
