The Experts below are selected from a list of 309 Experts worldwide ranked by ideXlab platform
Tsutomu Douchi - One of the best experts on this subject based on the ideXlab platform.
-
New hemostatic method using Mohs' paste for fatal Genital Bleeding in advanced cervical cancer.
Gynecologic oncology case reports, 2013Co-Authors: Shintaro Yanazume, Yumi Yanazume, Haruhiko Douzono, Kazuto Iio, Tsutomu DouchiAbstract:Atypical Genital Bleeding is the most common and serious manifestation in patients with advanced gynecologic malignancies. In the 1930s, Frederic F Mohs originated a method for the chemical fixation of a cutaneous tumor using 20% of zinc chloride (Mohs' paste), which causes necrosis, but preserves microscopic details of the tissue (Mohs et al., 1941). He developed a technique of micrographic tumor serial excision as a chemosurgery technique (Mohs et al., 1941; Swanson, 1983). Nowadays, such a technique has become widely accepted as the treatment option for primary or recurrent cutaneous neoplasms (Swanson, 1983). Recent reports show that hemostasis could be achieved using Mohs' paste in a malignant wound including unresectable breast cancer and skin metastasis of various kinds of cancer (Kakimoto et al., 2010). We describe a successful treatment using Mohs' paste for life-threatening Genital Bleeding in a patient with recurrent cervical cancer. This is an important case report with promising results for future patients and this clearly provides evidence that Mohs' paste can save a patient's life from fatal Genital Bleeding of the uterine cervix.
-
Clinical usefulness of Mohs' paste for Genital Bleeding from the uterine cervix or vaginal stump in gynecologic cancer
Journal of palliative medicine, 2012Co-Authors: Yumi Yanazume, Shintaro Yanazume, Haruhiko Douzono, Kazuto Iio, Nobuko Kojima, Keika Mukaihara, Tsutomu DouchiAbstract:Abstract Background: Atypical Genital Bleeding due to gynecologic cancer not only impairs patients' quality of life (QOL), but also becomes a major causative factor of death. We report the clinical usefulness of Mohs' paste for Genital Bleeding from the uterine cervix or vaginal stump in patients with recurrent gynecologic cancer. Method and Results: Eight patients with gynecologic cancer were enrolled between January 2010 and March 2012. Mohs' paste was directly applied to the Bleeding tumor. In patients with recurrent Genital Bleeding after the application of Mohs' paste, the technique was repeated. The effect of this procedure continued for 4 days to 1 year. The effect of Mohs' paste continued for 3 months or more in three patients. None of the eight patients have died of Genital Bleeding. Conclusions: The use of Mohs' paste is safe and convenient for massive Genital Bleeding from the uterine cervix or vaginal stump due to recurrent gynecologic cancer. However, our study does have some limitations incl...
-
successful management of uterine arteriovenous malformation by ligation of feeding artery after unsuccessful uterine artery embolization
Journal of Obstetrics and Gynaecology Research, 2009Co-Authors: Daisaku Yokomine, Mitsuhiro Yoshinaga, Yasutaka Baba, Takashi Matsuo, Yoshifumi Iguro, Masayuki Nakajo, Tsutomu DouchiAbstract:Uterine arteriovenous malformation (AVM) is a rare and potentially life-threatening disease. The present report describes a postmenopausal patient with uterine AVM manifesting recurrent, massive Genital Bleeding. Uterine artery embolization (UAE) was scheduled before hysterectomy, but UAE was unsuccessful due to the dilated, tortuous internal iliac arteries, and extremely rapid arterial blood flow. Hysterectomy appeared to carry a potential risk of massive blood loss due to multiple dilated vessels around the uterine corpus and cervix. Therefore, six arteries feeding the uterus were surgically ligated. At 10 months after the operation there have been no episodes of atypical Genital Bleeding.
Gregory Mohr - One of the best experts on this subject based on the ideXlab platform.
-
Uterine artery embolization: An underused method of controlling pelvic hemorrhage
American journal of obstetrics and gynecology, 1997Co-Authors: Suresh Vedantham, Scott C. Goodwin, Bruce Mclucas, Gregory MohrAbstract:Transcatheter arterial embolization has recently emerged as a highly effective percutaneous technique for controlling acute and chronic Genital Bleeding in a wide variety of obstetric and gynecologic disorders. Benefits for the patient and health care system have included low complication rates, avoidance of surgical risks, fertility preservation, and shorter hospitalizations. In this article the current indications for pelvic embolotherapy, types of embolotherapy, technical considerations, immediate success rates, causes of failure, complications, and outcome expectations are discussed. Our comprehensive literature review and clinical experience suggest that embolization should be used before surgical treatment of nonmalignant pelvic Bleeding in many clinical settings, including postpartum, postcesarean, and postoperative Bleeding. It is our strong belief that this form of therapy is underused, and the primary purpose of this article is to emphasize its developing role as a highly effective, relatively noninvasive method of treating Genital Bleeding.
-
CURRENT DEVELOPMENT Uterine artery embolization: An controlling pelvic hemorrhage underused method of
1997Co-Authors: Suresh Vedantham, Scott C. Goodwin, Bruce Mclucas, Gregory MohrAbstract:causes of failure, complications, and outcome expectations are discussed. Our comprehensive literature review and clinical experience suggest that embolization should be used before surgical treatment of nonmalignant pelvic Bleeding in many clinical settings, including postpartum, postcesarean, and postoperative Bleeding. It is our strong belief that this form of therapy is underused, and the primary purpose of this article is to emphasize its developing role as a highly effective, relatively noninvasive method of treating Genital Bleeding. (Am J Obstet Gynecol 1997;176:938-48.)
Shintaro Yanazume - One of the best experts on this subject based on the ideXlab platform.
-
Tumor Bleeding requiring intervention and the correlation with anemia in uterine cervical cancer for definitive radiotherapy.
Japanese journal of clinical oncology, 2018Co-Authors: Shintaro Yanazume, Noriko Karakida, Ryutaro Higashi, Mika Fukuda, Shinichi Togami, Masaki Kamio, Shunichiro Ota, Hiroaki KobayashiAbstract:Background The prognostic impact of tumor Bleeding requiring intervention and the correlation with anemia on the survival outcome of cervical cancer radiotherapy is unclear. Methods One hundred and ninety-six patients requiring hemostatic intervention between January 2006 and March 2014 were retrospectively investigated. The correlation between anemia and Bleeding during radiotherapy, the prognostic impact of Genital Bleeding during radiotherapy and the influence of blood transfusion were estimated. Results None of the patients had incomplete or prolonged treatment exceeding 1 week due to Bleeding. All tumor Bleeding could be controlled by gauze packing, and no patients suffered from fatal Genital Bleeding. Bleeding significantly correlated with progression-free survival (P = 0.015) and overall survival (P = 0.048). Regarding the risk factors of anemia: age (P = 0.043), FIGO stage (P < 0.001), tumor diameter (P < 0.001), and Bleeding (P = 0.002) were significant. Multivariate analysis revealed FIGO stage (Odds Ratio: 2.360; 95% CI = 1.202-4.633; P = 0.013), tumor diameter (Odds Ratio: 2.089; 95% CI = 1.048-4.162; P = 0.036) and Bleeding (Odds Ratio: 2.226; 95% CI = 1.052-4.709; P = 0.036) were independent to anemia. Anemia (Hazard Ratio = 1.894; 95% CI = 1.082-3.318; P = 0.025) was only independently correlated with progression free survival, while Bleeding (Hazard Ratio = 1.156; 95% CI = 0.556-2.406; P = 0.698) had no independent correlation. Blood transfusion did not improve progression-free survival in patients with anemia or Genital Bleeding (P = 0.742). Conclusion We have proved that Genital Bleeding requiring intervention during cervical cancer radiotherapy is a negligible prognostic factor and is the independent factor for causing anemia. Easily Bleeding tumors are potential prognostic markers, which are not effectively treated using existing radiotherapy.
-
Genital Bleeding hemostasis in gynecologic neoplasm with balloon tamponade: New treatment option.
The journal of obstetrics and gynaecology research, 2017Co-Authors: Noriko Karakida, Shintaro Yanazume, Marie Mori, Natsuko Uchida, Akio Tokudome, Hiroaki KobayashiAbstract:Genital Bleeding is the most common and serious complication in gynecologic malignancy. Different techniques are available for the control of severe Bleeding, but standard treatment strategies have not been determined. Herein we report on the successful use of the balloon technique in two cases of Genital Bleeding in uterine neoplasm. The first case was of advanced cervical cancer with massive Genital Bleeding during radiotherapy. A metreurynter (mini-metro) was inserted into the vagina and hemostasis was indirectly achieved in the vaginal hematoma. The other case was of postoperative recurrent Bleeding after cervical conization. A Foley balloon catheter was inserted into the endocervical canal and balloon tamponade directly stopped the Bleeding. This technique is safe for massive Genital Bleeding in some cases of gynecological cancer, and can be conventionally performed regardless of the facility or department. The need for invasive treatment for fatal Bleeding in gynecological cancer in which gauze packing is ineffective may be avoided by balloon tamponade without serious complications.
-
New hemostatic method using Mohs' paste for fatal Genital Bleeding in advanced cervical cancer.
Gynecologic oncology case reports, 2013Co-Authors: Shintaro Yanazume, Yumi Yanazume, Haruhiko Douzono, Kazuto Iio, Tsutomu DouchiAbstract:Atypical Genital Bleeding is the most common and serious manifestation in patients with advanced gynecologic malignancies. In the 1930s, Frederic F Mohs originated a method for the chemical fixation of a cutaneous tumor using 20% of zinc chloride (Mohs' paste), which causes necrosis, but preserves microscopic details of the tissue (Mohs et al., 1941). He developed a technique of micrographic tumor serial excision as a chemosurgery technique (Mohs et al., 1941; Swanson, 1983). Nowadays, such a technique has become widely accepted as the treatment option for primary or recurrent cutaneous neoplasms (Swanson, 1983). Recent reports show that hemostasis could be achieved using Mohs' paste in a malignant wound including unresectable breast cancer and skin metastasis of various kinds of cancer (Kakimoto et al., 2010). We describe a successful treatment using Mohs' paste for life-threatening Genital Bleeding in a patient with recurrent cervical cancer. This is an important case report with promising results for future patients and this clearly provides evidence that Mohs' paste can save a patient's life from fatal Genital Bleeding of the uterine cervix.
-
Clinical usefulness of Mohs' paste for Genital Bleeding from the uterine cervix or vaginal stump in gynecologic cancer
Journal of palliative medicine, 2012Co-Authors: Yumi Yanazume, Shintaro Yanazume, Haruhiko Douzono, Kazuto Iio, Nobuko Kojima, Keika Mukaihara, Tsutomu DouchiAbstract:Abstract Background: Atypical Genital Bleeding due to gynecologic cancer not only impairs patients' quality of life (QOL), but also becomes a major causative factor of death. We report the clinical usefulness of Mohs' paste for Genital Bleeding from the uterine cervix or vaginal stump in patients with recurrent gynecologic cancer. Method and Results: Eight patients with gynecologic cancer were enrolled between January 2010 and March 2012. Mohs' paste was directly applied to the Bleeding tumor. In patients with recurrent Genital Bleeding after the application of Mohs' paste, the technique was repeated. The effect of this procedure continued for 4 days to 1 year. The effect of Mohs' paste continued for 3 months or more in three patients. None of the eight patients have died of Genital Bleeding. Conclusions: The use of Mohs' paste is safe and convenient for massive Genital Bleeding from the uterine cervix or vaginal stump due to recurrent gynecologic cancer. However, our study does have some limitations incl...
Sean Jooste - One of the best experts on this subject based on the ideXlab platform.
-
Coital Bleeding and HIV risks among men and women in Cape Town, South Africa
Sexually transmitted diseases, 2006Co-Authors: Seth C. Kalichman, Leickness C. Simbayi, Demetria Cain, Charsey Cherry, Sean JoosteAbstract:South Africa has one of the worlds fastest growing HIV epidemics. Genital Bleeding during sexual intercourse may play a role in facilitating HIV transmission in South Africa. The purpose of this study was to examine the prevalence and sources of coital Bleeding among men and women living in a Cape Town South Africa township. A purposive sample of 464 men and 531 women completed anonymous street intercept surveys of HIV risk history and sexual behaviors. Thirty-one percent of men and 26% of women had a lifetime history of engaging in sexual intercourse that involved Genital Bleeding and 21% of men and 16% of women reported coital Bleeding in the previous 3 months. Over 75% of coital Bleeding was attributed to menses. Across genders and controlling for demographic sexual behavior and life history factors coital Bleeding in the previous 3 months was associated with being an indigenous African having multiple sexual partners and higher rates of unprotected intercourse during that time period. People who reported coital Bleeding were over times more likely to have been diagnosed with a sexually transmitted infection even after controlling for having had Genital ulcers. Coital Bleeding may be common in South Africa. Prevention messages that promote condom use or refraining from sex when there is Genital Bleeding are therefore needed. (authors)
Suresh Vedantham - One of the best experts on this subject based on the ideXlab platform.
-
Uterine artery embolization: An underused method of controlling pelvic hemorrhage
American journal of obstetrics and gynecology, 1997Co-Authors: Suresh Vedantham, Scott C. Goodwin, Bruce Mclucas, Gregory MohrAbstract:Transcatheter arterial embolization has recently emerged as a highly effective percutaneous technique for controlling acute and chronic Genital Bleeding in a wide variety of obstetric and gynecologic disorders. Benefits for the patient and health care system have included low complication rates, avoidance of surgical risks, fertility preservation, and shorter hospitalizations. In this article the current indications for pelvic embolotherapy, types of embolotherapy, technical considerations, immediate success rates, causes of failure, complications, and outcome expectations are discussed. Our comprehensive literature review and clinical experience suggest that embolization should be used before surgical treatment of nonmalignant pelvic Bleeding in many clinical settings, including postpartum, postcesarean, and postoperative Bleeding. It is our strong belief that this form of therapy is underused, and the primary purpose of this article is to emphasize its developing role as a highly effective, relatively noninvasive method of treating Genital Bleeding.
-
CURRENT DEVELOPMENT Uterine artery embolization: An controlling pelvic hemorrhage underused method of
1997Co-Authors: Suresh Vedantham, Scott C. Goodwin, Bruce Mclucas, Gregory MohrAbstract:causes of failure, complications, and outcome expectations are discussed. Our comprehensive literature review and clinical experience suggest that embolization should be used before surgical treatment of nonmalignant pelvic Bleeding in many clinical settings, including postpartum, postcesarean, and postoperative Bleeding. It is our strong belief that this form of therapy is underused, and the primary purpose of this article is to emphasize its developing role as a highly effective, relatively noninvasive method of treating Genital Bleeding. (Am J Obstet Gynecol 1997;176:938-48.)