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Didier Pittet - One of the best experts on this subject based on the ideXlab platform.

  • transmission and effect of multiple clusters of seasonal influenza in a swiss Geriatric Hospital
    Journal of the American Geriatrics Society, 2015
    Co-Authors: Leonardo Pagani, V Sauvan, Didier Pittet, Yves Thomas, Benedikt Huttner, Grigorios Notaridis, Laurent Kaiser, A Iten, Stéphan Juergen Harbarth
    Abstract:

    Objectives To investigate a nosocomial outbreak of influenza. Design Prospective outbreak investigation with active case finding and molecular typing. Setting A large academic Geriatric Hospital in Switzerland. Participants Elderly Hospitalized adults. Measurements Based on syndromic surveillance, a nosocomial influenza outbreak was suspected in February 2012. All suspected cases were screened for respiratory viruses using real-time reverse transcription polymerase chain reaction of nasopharyngeal swabs. Infection control procedures (droplet precautions with single room isolation whenever possible) were implemented for all suspected or confirmed cases. Specimens positive for influenza viruses were processed and sequenced whenever possible to track transmission dynamics. Results Respiratory samples from 155 suspected cases were analyzed during the outbreak period, of which 69 (44%) were positive for influenza virus, 26 (17%) were positive for other respiratory viruses, and 60 (39%) were negative. Three other cases fulfilled clinical criteria for influenza infection but were not sampled, and one individual was admitted with an already positive test, resulting in a total of 73 influenza cases, of which 62 (85%) were classified as nosocomial. Five distinct clusters of nosocomial transmission were identified using viral sequencing, with epidemiologically unexpected in-Hospital transmission dynamics. Seven of 23 patients who experienced influenza complications died. Sixteen healthcare workers experienced an influenza-like illness (overall vaccination rate, 36%). Conclusion Nosocomial influenza transmission caused more secondary cases than repeated community importation during this polyclonal outbreak. Molecular tools revealed complex transmission dynamics. Low healthcare worker vaccination rates and gaps in recommended infection control procedures are likely to have contributed to nosocomial spread of influenza, which remains a potentially life-threatening disease in elderly adults.

  • P169: Is patient participation useful to improve staff hand hygiene compliance in a Geriatric Hospital?
    Antimicrobial Resistance and Infection Control, 2013
    Co-Authors: V Sauvan, Y Registe Rameau, Leonardo Pagani, Didier Pittet
    Abstract:

    Methods We conducted a survey on the impact of feedback and patient participation on hand hygiene compliance at our institution in 2012 and included 5 of 16 wards at the Geriatric Hospital. Patients were randomly recruited by an infection control nurse in 2 of the 5 wards to investigate the potential for patients to be actively engaged in hand hygiene practices. Inclusion criteria were: a cognitive capability of >19 as measured by a Mini Mental State examination and a stable health condition. At day 0, patients were trained in hand hygiene indications that should be carried out by staff and by themselves. Patients were given a training brochure and a bottle of alcohol-based handrub, together with a questionnaire about their willingness to either carry out hand hygiene or remind staff of the procedure, if not accomplished. At day 7, included patients underwent an interview to assess their active participation.

  • Prevalence and prediction of previously unknown MRSA carriage on admission to a Geriatric Hospital
    Age and ageing, 2005
    Co-Authors: Hugo Sax, Stéphan Juergen Harbarth, Gaëtan Gavazzi, Nicole Henry, Jacques Schrenzel, Peter Rohner, Jean-pierre Michel, Didier Pittet
    Abstract:

    OBJECTIVES: to determine the prevalence and characteristics of previously unknown methicillin-resistant Staphylococcus aureus (MRSA) carriers at admission. DESIGN: two prospective case-control studies. SUBJECTS: 1,621 elderly patients were screened for MRSA carriage within 24 hours after admission to a Geriatric Hospital in Geneva, Switzerland. METHODS: risk factors associated with previously unknown MRSA carriage were determined in the derivation group, and the resulting risk score was evaluated in the validation cohort using logistic regression analysis. RESULTS: prevalence of MRSA carriage at admission increased from 7.3% (53/724 patients) in 2001 to 8.7% (78/897 patients) in 2003, with a corresponding prevalence of unknown MRSA carriers of 4.6 and 5.8%, respectively. Three variables were independently associated with previously unknown MRSA carriage: recent antibiotic treatment (adjusted OR (aOR) 2.3; 95% CI 1.0-5.1), intra-Hospital transfer (aOR 2.5; 95% CI 1.2-5.3), and Hospitalization in the past 2 years (aOR 2.7; 95% CI 1.1-6.7). In the validation cohort, the probability of MRSA carriage increased across risk scores: 0 point, 4% prevalence (6/146); 1 point, 15% (21/136); and

Anthony Serracino-inglott - One of the best experts on this subject based on the ideXlab platform.

  • Time and motion study for pharmacists' activities in a Geriatric Hospital
    International Journal of Pharmacy Practice, 2009
    Co-Authors: Francesca Wirth, Lilian M. Azzopardi, Marise Gauci, Maurice Zarb Adami, Anthony Serracino-inglott
    Abstract:

    Objectives This study aimed to identify and quantify activities undertaken by pharmacists in a Geriatric Hospital. Methods A data collection form was developed, validated and tested for applicability and practicality. Pharmacist activities were organised into three categories: Clinical, Administration and Others. Clinical activities incorporated patient discharge, patient admission, checking the ward controlled drugs record book, emergency trolley and patient medication trolley, prescription monitoring, ward round, discussion with health care professionals, and other professional activities; Administration activities included checking the ward medication stock and medication order; Others included break and inactive time. Observers conducted 6000 min of direct observation using a time and motion technique and observed the work activities of three pharmacists on three wards. Data were analysed using Microsoft Excel 2007 and SPSS version 16.0. Descriptive statistics were carried out. Key findings The time dedicated to Clinical activities was 3636 min (60.60%), Administration activities 1646 min (27.43%) and Others 718 min (11.97%). When considering total time in minutes for Clinical and Administration activities, ward round (1348 min), medication order (1255 min), patient discharge (723 min) and prescription monitoring (562 min) occupied most of the pharmacists' time. Ward round activities were subdivided into: patient profiling (545 min), actual ward round (668 min) and conference (135 min). Conclusions The time and motion study indicated that the pharmacists' time is mainly allocated to clinical activities. However, there is still a large proportion of time taken up by administrative activities, which can be conducted by non-pharmacist personnel, allowing more time to be directed to patient care.

Stéphan Juergen Harbarth - One of the best experts on this subject based on the ideXlab platform.

  • transmission and effect of multiple clusters of seasonal influenza in a swiss Geriatric Hospital
    Journal of the American Geriatrics Society, 2015
    Co-Authors: Leonardo Pagani, V Sauvan, Didier Pittet, Yves Thomas, Benedikt Huttner, Grigorios Notaridis, Laurent Kaiser, A Iten, Stéphan Juergen Harbarth
    Abstract:

    Objectives To investigate a nosocomial outbreak of influenza. Design Prospective outbreak investigation with active case finding and molecular typing. Setting A large academic Geriatric Hospital in Switzerland. Participants Elderly Hospitalized adults. Measurements Based on syndromic surveillance, a nosocomial influenza outbreak was suspected in February 2012. All suspected cases were screened for respiratory viruses using real-time reverse transcription polymerase chain reaction of nasopharyngeal swabs. Infection control procedures (droplet precautions with single room isolation whenever possible) were implemented for all suspected or confirmed cases. Specimens positive for influenza viruses were processed and sequenced whenever possible to track transmission dynamics. Results Respiratory samples from 155 suspected cases were analyzed during the outbreak period, of which 69 (44%) were positive for influenza virus, 26 (17%) were positive for other respiratory viruses, and 60 (39%) were negative. Three other cases fulfilled clinical criteria for influenza infection but were not sampled, and one individual was admitted with an already positive test, resulting in a total of 73 influenza cases, of which 62 (85%) were classified as nosocomial. Five distinct clusters of nosocomial transmission were identified using viral sequencing, with epidemiologically unexpected in-Hospital transmission dynamics. Seven of 23 patients who experienced influenza complications died. Sixteen healthcare workers experienced an influenza-like illness (overall vaccination rate, 36%). Conclusion Nosocomial influenza transmission caused more secondary cases than repeated community importation during this polyclonal outbreak. Molecular tools revealed complex transmission dynamics. Low healthcare worker vaccination rates and gaps in recommended infection control procedures are likely to have contributed to nosocomial spread of influenza, which remains a potentially life-threatening disease in elderly adults.

  • Prevalence and prediction of previously unknown MRSA carriage on admission to a Geriatric Hospital
    Age and ageing, 2005
    Co-Authors: Hugo Sax, Stéphan Juergen Harbarth, Gaëtan Gavazzi, Nicole Henry, Jacques Schrenzel, Peter Rohner, Jean-pierre Michel, Didier Pittet
    Abstract:

    OBJECTIVES: to determine the prevalence and characteristics of previously unknown methicillin-resistant Staphylococcus aureus (MRSA) carriers at admission. DESIGN: two prospective case-control studies. SUBJECTS: 1,621 elderly patients were screened for MRSA carriage within 24 hours after admission to a Geriatric Hospital in Geneva, Switzerland. METHODS: risk factors associated with previously unknown MRSA carriage were determined in the derivation group, and the resulting risk score was evaluated in the validation cohort using logistic regression analysis. RESULTS: prevalence of MRSA carriage at admission increased from 7.3% (53/724 patients) in 2001 to 8.7% (78/897 patients) in 2003, with a corresponding prevalence of unknown MRSA carriers of 4.6 and 5.8%, respectively. Three variables were independently associated with previously unknown MRSA carriage: recent antibiotic treatment (adjusted OR (aOR) 2.3; 95% CI 1.0-5.1), intra-Hospital transfer (aOR 2.5; 95% CI 1.2-5.3), and Hospitalization in the past 2 years (aOR 2.7; 95% CI 1.1-6.7). In the validation cohort, the probability of MRSA carriage increased across risk scores: 0 point, 4% prevalence (6/146); 1 point, 15% (21/136); and

Francesca Wirth - One of the best experts on this subject based on the ideXlab platform.

  • Time and motion study for pharmacists' activities in a Geriatric Hospital
    International Journal of Pharmacy Practice, 2009
    Co-Authors: Francesca Wirth, Lilian M. Azzopardi, Marise Gauci, Maurice Zarb Adami, Anthony Serracino-inglott
    Abstract:

    Objectives This study aimed to identify and quantify activities undertaken by pharmacists in a Geriatric Hospital. Methods A data collection form was developed, validated and tested for applicability and practicality. Pharmacist activities were organised into three categories: Clinical, Administration and Others. Clinical activities incorporated patient discharge, patient admission, checking the ward controlled drugs record book, emergency trolley and patient medication trolley, prescription monitoring, ward round, discussion with health care professionals, and other professional activities; Administration activities included checking the ward medication stock and medication order; Others included break and inactive time. Observers conducted 6000 min of direct observation using a time and motion technique and observed the work activities of three pharmacists on three wards. Data were analysed using Microsoft Excel 2007 and SPSS version 16.0. Descriptive statistics were carried out. Key findings The time dedicated to Clinical activities was 3636 min (60.60%), Administration activities 1646 min (27.43%) and Others 718 min (11.97%). When considering total time in minutes for Clinical and Administration activities, ward round (1348 min), medication order (1255 min), patient discharge (723 min) and prescription monitoring (562 min) occupied most of the pharmacists' time. Ward round activities were subdivided into: patient profiling (545 min), actual ward round (668 min) and conference (135 min). Conclusions The time and motion study indicated that the pharmacists' time is mainly allocated to clinical activities. However, there is still a large proportion of time taken up by administrative activities, which can be conducted by non-pharmacist personnel, allowing more time to be directed to patient care.

Chen Zi-hui - One of the best experts on this subject based on the ideXlab platform.

  • Correlation Factors of Working State of Medical Staffs in Yunnan Geriatric Hospital
    Journal of Kunming Medical University, 2010
    Co-Authors: Chen Zi-hui
    Abstract:

    Objective To explore the effect of psychological status on the working state of staffs in Yunnan Geriatric Hospital in order to improve the quality of medical works,and to carry out the High Quality Nursing Service Demonstration Projects.Method 123 medical staffs in our Hospital were evaluated by psychological questionnaires.Results 101 valid questionnaires were collected.The total positive rate of SCL-90 was 9.9%.Doctors accounted for 6.06% and nurses accounted for 11.76% in the positive staffs with psychological problems.The main psychological symptoms were compulsion,paranoia,depression,anxiety and somatization.The quality of life was positively correlated with self-esteem,and negatively correlated with fatigue,sleep,and SCL-90 symptoms.Fatigue was negatively correlated with working time.Conclusions The psychological status of medical staff need to be concerned.We should alleviate the mental stress of medical staff from the perspective of Management Science,and train them with professional mental stress management,so that we can improve their life quality and working efficiency.