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Gordon G. Birch - One of the best experts on this subject based on the ideXlab platform.
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hydration properties of na k mg Gluconates and gluconate sucrose mixtures and their possible taste effect
Food Chemistry, 2000Co-Authors: V. Aroulmoji, Mohamed Mathlouthi, Gordon G. BirchAbstract:Abstract Density and ultrasonic velocity were measured in aqueous solutions of sodium, potassium and magnesium gluconate as a function of increasing concentration. Apparent molar volume (AMV), apparent specific volume (ASV), isentropic apparent molar (IAMC) compressibility and hydration numbers were calculated from the experimental data. The results show that AMV and ASV increase as the concentration of Gluconates is increased. This is interpreted on the basis of molecular interaction between solute and solvent molecules. These measurements were repeated by adding Na, K and Mg Gluconates to 10 and 20% sucrose solution with the aim of understanding the influence of Gluconates on water association in sucrose solutions. The results show that the values of IAMC decrease as the concentration is increased. Moreover, Mg gluconate shows more negative IAMC than Na and K Gluconates. The observed results are explained on the basis of the hydration of Gluconates in the sucrose-water system. NMR relaxation rates (R 1 and R 2 ) show an increase as the concentration of the gluconate is increased. On the other hand, the results of Na, K and Mg gluconate in 10 and 20% sucrose solutions demonstrated that the effect of Mg gluconate enhances the hydration properties of sucrose water mixtures more than Na and K gluconate. The overall results show the importance of water interactions with sapid molecules and this can lead to a better understanding of their tastes.
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Hydration properties of Na, K, Mg Gluconates and gluconate/sucrose mixtures and their possible taste effect
Food Chemistry, 2000Co-Authors: V. Aroulmoji, Mohamed Mathlouthi, Gordon G. BirchAbstract:Abstract Density and ultrasonic velocity were measured in aqueous solutions of sodium, potassium and magnesium gluconate as a function of increasing concentration. Apparent molar volume (AMV), apparent specific volume (ASV), isentropic apparent molar (IAMC) compressibility and hydration numbers were calculated from the experimental data. The results show that AMV and ASV increase as the concentration of Gluconates is increased. This is interpreted on the basis of molecular interaction between solute and solvent molecules. These measurements were repeated by adding Na, K and Mg Gluconates to 10 and 20% sucrose solution with the aim of understanding the influence of Gluconates on water association in sucrose solutions. The results show that the values of IAMC decrease as the concentration is increased. Moreover, Mg gluconate shows more negative IAMC than Na and K Gluconates. The observed results are explained on the basis of the hydration of Gluconates in the sucrose-water system. NMR relaxation rates (R 1 and R 2 ) show an increase as the concentration of the gluconate is increased. On the other hand, the results of Na, K and Mg gluconate in 10 and 20% sucrose solutions demonstrated that the effect of Mg gluconate enhances the hydration properties of sucrose water mixtures more than Na and K gluconate. The overall results show the importance of water interactions with sapid molecules and this can lead to a better understanding of their tastes.
Steven R. Alexander - One of the best experts on this subject based on the ideXlab platform.
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Sodium ferric gluconate therapy in renal transplant and renal failure patients.
Pediatric Nephrology, 2000Co-Authors: Peter D. Yorgin, Amir Belson, Minnie M. Sarwal, Steven R. AlexanderAbstract:Intravenous infusion of sodium ferric gluconate (Ferrlecit) has been reported to be effective and safe in pediatric and adult hemodialysis patients with iron depletion. We sought to expand on the previous studies by treating 13 consecutive pediatric renal failure and renal transplant patients with sodium ferric gluconate doses that were higher than previously reported. Efficacy was defined as: (1) an increase in hematocrit of ≥3 vol% with no change or a decrease in erythropoietin dose or (2) a stable hematocrit with a decrease of ≥25% in the erythropoietin, 2 weeks to 2 months after sodium ferric gluconate infusion. Two dosing strategies were employed: (1) high dose, where single dose sodium ferric gluconate (mg) ≈ calculated iron deficit, and (2) sodium ferric gluconate, 62.5 mg/dose for children 40 kg, infused on eight consecutive hemodialysis runs. There was only one self-limited adverse reaction in 60 doses. Three patients with previous adverse reactions to iron dextran tolerated sodium ferric gluconate without adverse effect. Sodium ferric gluconate was efficacious in eight out of ten patients that received a cumulative dose >5 mg/kg. The mean hematocrit increased 30.3±7.8 to 36.4±4.4 vol% (P=0.04) and the mean erythropoietin dose decreased 251.5±149.1 to 100.7±113.0 units/kg/week (P=0.02). Although sodium ferric gluconate appears to be effective and safe at the doses used, multicenter, prospective pharmacokinetic and clinical trials of sodium ferric gluconate should be conducted in children.
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Sodium ferric gluconate therapy in renal transplant and renal failure patients.
Pediatric nephrology (Berlin Germany), 2000Co-Authors: Peter D. Yorgin, Amir Belson, Minnie M. Sarwal, Steven R. AlexanderAbstract:Intravenous infusion of sodium ferric gluconate (Ferrlecit) has been reported to be effective and safe in pediatric and adult hemodialysis patients with iron depletion. We sought to expand on the previous studies by treating 13 consecutive pediatric renal failure and renal transplant patients with sodium ferric gluconate doses that were higher than previously reported. Efficacy was defined as: (1) an increase in hematocrit of > or = 3 vol% with no change or a decrease in erythropoietin dose or (2) a stable hematocrit with a decrease of > or = 25% in the erythropoietin, 2 weeks to 2 months after sodium ferric gluconate infusion. Two dosing strategies were employed: (1) high dose, where single dose sodium ferric gluconate (mg) approximately calculated iron deficit, and (2) sodium ferric gluconate, 62.5 mg/dose for children < 40 kg, 125 mg/dose for children > 40 kg, infused on eight consecutive hemodialysis runs. There was only one self-limited adverse reaction in 60 doses. Three patients with previous adverse reactions to iron dextran tolerated sodium ferric gluconate without adverse effect. Sodium ferric gluconate was efficacious in eight out of ten patients that received a cumulative dose > 5 mg/kg. The mean hematocrit increased 30.3 +/- 7.8 to 36.4 +/- 4.4 vol% (P = 0.04) and the mean erythropoietin dose decreased 251.5 +/- 149.1 to 100.7 +/- 113.0 units/kg/week (P = 0.02). Although sodium ferric gluconate appears to be effective and safe at the doses used, multicenter, prospective pharmacokinetic and clinical trials of sodium ferric gluconate should be conducted in children.
V. Aroulmoji - One of the best experts on this subject based on the ideXlab platform.
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hydration properties of na k mg Gluconates and gluconate sucrose mixtures and their possible taste effect
Food Chemistry, 2000Co-Authors: V. Aroulmoji, Mohamed Mathlouthi, Gordon G. BirchAbstract:Abstract Density and ultrasonic velocity were measured in aqueous solutions of sodium, potassium and magnesium gluconate as a function of increasing concentration. Apparent molar volume (AMV), apparent specific volume (ASV), isentropic apparent molar (IAMC) compressibility and hydration numbers were calculated from the experimental data. The results show that AMV and ASV increase as the concentration of Gluconates is increased. This is interpreted on the basis of molecular interaction between solute and solvent molecules. These measurements were repeated by adding Na, K and Mg Gluconates to 10 and 20% sucrose solution with the aim of understanding the influence of Gluconates on water association in sucrose solutions. The results show that the values of IAMC decrease as the concentration is increased. Moreover, Mg gluconate shows more negative IAMC than Na and K Gluconates. The observed results are explained on the basis of the hydration of Gluconates in the sucrose-water system. NMR relaxation rates (R 1 and R 2 ) show an increase as the concentration of the gluconate is increased. On the other hand, the results of Na, K and Mg gluconate in 10 and 20% sucrose solutions demonstrated that the effect of Mg gluconate enhances the hydration properties of sucrose water mixtures more than Na and K gluconate. The overall results show the importance of water interactions with sapid molecules and this can lead to a better understanding of their tastes.
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Hydration properties of Na, K, Mg Gluconates and gluconate/sucrose mixtures and their possible taste effect
Food Chemistry, 2000Co-Authors: V. Aroulmoji, Mohamed Mathlouthi, Gordon G. BirchAbstract:Abstract Density and ultrasonic velocity were measured in aqueous solutions of sodium, potassium and magnesium gluconate as a function of increasing concentration. Apparent molar volume (AMV), apparent specific volume (ASV), isentropic apparent molar (IAMC) compressibility and hydration numbers were calculated from the experimental data. The results show that AMV and ASV increase as the concentration of Gluconates is increased. This is interpreted on the basis of molecular interaction between solute and solvent molecules. These measurements were repeated by adding Na, K and Mg Gluconates to 10 and 20% sucrose solution with the aim of understanding the influence of Gluconates on water association in sucrose solutions. The results show that the values of IAMC decrease as the concentration is increased. Moreover, Mg gluconate shows more negative IAMC than Na and K Gluconates. The observed results are explained on the basis of the hydration of Gluconates in the sucrose-water system. NMR relaxation rates (R 1 and R 2 ) show an increase as the concentration of the gluconate is increased. On the other hand, the results of Na, K and Mg gluconate in 10 and 20% sucrose solutions demonstrated that the effect of Mg gluconate enhances the hydration properties of sucrose water mixtures more than Na and K gluconate. The overall results show the importance of water interactions with sapid molecules and this can lead to a better understanding of their tastes.
Peter D. Yorgin - One of the best experts on this subject based on the ideXlab platform.
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Sodium ferric gluconate therapy in renal transplant and renal failure patients.
Pediatric Nephrology, 2000Co-Authors: Peter D. Yorgin, Amir Belson, Minnie M. Sarwal, Steven R. AlexanderAbstract:Intravenous infusion of sodium ferric gluconate (Ferrlecit) has been reported to be effective and safe in pediatric and adult hemodialysis patients with iron depletion. We sought to expand on the previous studies by treating 13 consecutive pediatric renal failure and renal transplant patients with sodium ferric gluconate doses that were higher than previously reported. Efficacy was defined as: (1) an increase in hematocrit of ≥3 vol% with no change or a decrease in erythropoietin dose or (2) a stable hematocrit with a decrease of ≥25% in the erythropoietin, 2 weeks to 2 months after sodium ferric gluconate infusion. Two dosing strategies were employed: (1) high dose, where single dose sodium ferric gluconate (mg) ≈ calculated iron deficit, and (2) sodium ferric gluconate, 62.5 mg/dose for children 40 kg, infused on eight consecutive hemodialysis runs. There was only one self-limited adverse reaction in 60 doses. Three patients with previous adverse reactions to iron dextran tolerated sodium ferric gluconate without adverse effect. Sodium ferric gluconate was efficacious in eight out of ten patients that received a cumulative dose >5 mg/kg. The mean hematocrit increased 30.3±7.8 to 36.4±4.4 vol% (P=0.04) and the mean erythropoietin dose decreased 251.5±149.1 to 100.7±113.0 units/kg/week (P=0.02). Although sodium ferric gluconate appears to be effective and safe at the doses used, multicenter, prospective pharmacokinetic and clinical trials of sodium ferric gluconate should be conducted in children.
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Sodium ferric gluconate therapy in renal transplant and renal failure patients.
Pediatric nephrology (Berlin Germany), 2000Co-Authors: Peter D. Yorgin, Amir Belson, Minnie M. Sarwal, Steven R. AlexanderAbstract:Intravenous infusion of sodium ferric gluconate (Ferrlecit) has been reported to be effective and safe in pediatric and adult hemodialysis patients with iron depletion. We sought to expand on the previous studies by treating 13 consecutive pediatric renal failure and renal transplant patients with sodium ferric gluconate doses that were higher than previously reported. Efficacy was defined as: (1) an increase in hematocrit of > or = 3 vol% with no change or a decrease in erythropoietin dose or (2) a stable hematocrit with a decrease of > or = 25% in the erythropoietin, 2 weeks to 2 months after sodium ferric gluconate infusion. Two dosing strategies were employed: (1) high dose, where single dose sodium ferric gluconate (mg) approximately calculated iron deficit, and (2) sodium ferric gluconate, 62.5 mg/dose for children < 40 kg, 125 mg/dose for children > 40 kg, infused on eight consecutive hemodialysis runs. There was only one self-limited adverse reaction in 60 doses. Three patients with previous adverse reactions to iron dextran tolerated sodium ferric gluconate without adverse effect. Sodium ferric gluconate was efficacious in eight out of ten patients that received a cumulative dose > 5 mg/kg. The mean hematocrit increased 30.3 +/- 7.8 to 36.4 +/- 4.4 vol% (P = 0.04) and the mean erythropoietin dose decreased 251.5 +/- 149.1 to 100.7 +/- 113.0 units/kg/week (P = 0.02). Although sodium ferric gluconate appears to be effective and safe at the doses used, multicenter, prospective pharmacokinetic and clinical trials of sodium ferric gluconate should be conducted in children.
Xiaodong Shen - One of the best experts on this subject based on the ideXlab platform.
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Influence of sodium gluconate on the performance and hydration of Portland cement
Construction and Building Materials, 2015Co-Authors: Shenbiao Zhang, Xiaodong ShenAbstract:Abstract Sodium gluconate is commonly used to delay the setting of cement and concrete. This study investigated the effects of sodium gluconate on the physical properties and structure of Portland cement. Sodium gluconate improved the compressive strength at 3 and 28 days, delayed cement setting and increased the fluidity of the Portland cement mortar. Less than 0.03% sodium gluconate promoted the formation of ettringite (AFt) at early age. A dosage of 1.0% sodium gluconate significantly inhibited the reaction between C3A and CaSO4·2H2O. Sodium gluconate delayed the hydration reaction of C3S, which increased the duration of the induction period. Sodium gluconate had only a slight effect on the hydration reaction of the ferrite phase. The pore distribution and porosity of the cement paste were not improved due to the decrease in hydration.